Background : Insulin-like growth factor 1 (IGF-1) appears to enhance the differentiation of osteoblasts and to activate the mineralization of bone. Hence, the aim of this study was to investigate the effects of ginseng complex on the remodeling of rats tibia. Methods and Results : Ginseng complex significantly increased serum IGF-1 by 58% and 34.5% than the control, respectively. Treatment with α-amylase when manufacturing these extracts remarkably increased the concentration of IGF-1 by 63% and 36% above the control, respectively. This ways that this ginseng complex, especially α-amylase treated extracts, contained a higher level of IGF-1 secretion in the ginseng complex groups. In addition, increases of 8% in femuf length were found after 12 weeks of oral administration with ginseng complex (300mg/kg). Conclusion : These results mean that ginseng complex have beneficial effects on bone effects on bone growth via IGF-1.

Background : Our animal model of stress contained two components: (1) acute trauma, immobilization of rats in close proximity to a cat twice in 10 days, and (2) chronic social instability, 31 days of randomized housing of cage cohorts. Here we tested the hypothesis that daily social stimulation would block the development of the stress. Methods and Results : Beginning 24 h after the first cat exposure, adult male rats were given our established stress model, alone or in conjunction with daily social stimulation, in which all rats within a group interacted in a large apparatus for 2 h each day for the final 30 days. All behavioral, for example, anxiety, memory, startle testing, and physiological assessments, for example, body growth, organ weights, and corticosterone levels, took place following completion of the psychosocial stress period. Conclusion : From the above study, V. fauriei possess significant anti-stress properties and can be used for the treatment of stress-induced disorders.

Background : Reactive oxygen species (ROS), whether produced endogenously as a consequence of normal cell functions or derived from external sources, pose a constant threat to cells living in an aerobic environment as they can result in severe damage to DNA, protein, and lipids. The effects of Valeriana fauriei extract and fractions on hydrogen peroxide-induced neuronal cell damage are studied. Methods and Results : Oxidative stress plays an important role in the pathological process of neurodegenerative diseases. Valeriana fauriei extract (VFE) and EA fractions (VFEA) was investigated total phenolic contents using method. VFE of total phenolic contents had 2.54 ± 0.01 mg/g, also, VFEA had a 18.78 ± 0.03 mg/g. High phenolic content of the VFEA is expected to better the inhibition of oxidative stress. VFE and VFEA were experimented to inhibit ROS induced 200 μM 3-morpholinosydnonimine (SIN-1). VFE of inhibit SIN-1 induced-ROS dose dependently and signficantly. In addition, VFEA inhibition was also dose dependant and significant. Moreover, Treatment of SH-SY5Y and SK-N-SH cells with VFEA significantly reduced hydrogen peroxide-induced generation of intercellular ROS. Conclusion : From the above results, we may suggest that VFEA might have useful as a material for functional food and pharmaceutics for the pathological process of neurodegenerative diseases.

Purpose: this study was to gain a full understanding of the experiences of sports counselor trainees during counseling training. For this purpose, this study explored the experiences and the meaning of counselors’ development. Methods: A phenomenological study was utilized and 6 participants who had several experiences of sports counseling were selected for the study. 3 categories, 8 subcategories, and 24 subjects were derived from in depth interviews and focus group interview. Data were analyzed based on the open coding, axial coding, and selective coding procedure of phenomenological theory. Results: First, trainees were motivated to introduce psychological skills to athletes, at the same time they were worried about immaturity of themselves as counselors. Second, trainees faced the difficulties of reality such as doubts about the effectiveness of counseling, differences between on-site and lectures. Also, trainees should apply different counseling techniques depending on the speciality of sport. Third, trainees grew through a variety of experiences as sport counselors. They preached the importance of sport counseling to the organizations such as professional teams and schools. Conclusion: Trainees developed their skills and professional counseling abilities through their training. This research may be used as basic data for counselors to adapt to sports setting, and to achieve better and professional counseling.