파골세포양 거대세포형 미분화 암종은 췌장암의 1%만을 차지하는 흔치 않은 암종으로 알려져 있다. 저자들은 39세 남자에게서 진단된, 수술 및 항암치료를 시행한 1예를 소개하고자 한다.

PURPOSES : Previously, the expansion state of the concrete pavement in which AAR occurred could not be determined. Because the current situation has not been evaluated, it has been difficult to prepare an appropriate response. In this study, a method for calculating the expansion amount of concrete pavement using the stiffness damage test (SDT) is proposed. METHODS : The SDT method was examined through a literature review. For the laboratory tests, specimens that generated AAR were produced based on the mix design (2018) of the Korea Expressway Corporation. SDT was used to calculate various mechanical properties, and their correlation with the expansion amount was reviewed. RESULTS : Using the SDT, various mechanical properties(elastic modulus, hysteresis area, plastic deformation, plastic deformation index, stiffness damage index, and nonlinear index) were calculated based on the expansion rate of the AAR. The elastic modulus was evaluated as the best predictor of the expansion rate. Thus, if the elastic modulus is calculated using SDT, a prediction equation can be used to calculate the amount of AAR expansion. This equation will need to be supplemented by further research. CONCLUSIONS : SDT was used to confirm that the expansion state due to the AAR of the concrete pavement could be indirectly evaluated. Among the mechanical properties related to SDT, the elastic modulus was found to be the most suitable for predicting the amount of expansion.

산업과 기술의 발전으로 인해 수계로의 화학물질 배출이 증가하고, 이로 인해 환경오염과 인체 건강에 부정적인 영향을 미치 는 위험이 더욱 증가하였다. 따라서, 수질을 종합적으로 평가할 수 있는 생태독성평가의 중요성이 강조되고 있다. 본 연구에서는 렌즈프 리 그림자 이미징 기술을 활용한 Cellytics 플랫폼을 소개하며, 화학물질에 의한 로티퍼(Brachionus plicatilis)와 미세조류(Dunaliella tertiolecta) 의 생물학적 변화를 신속하게 측정하고 독성을 분석하는 기법을 제안한다. 이를 위해 로티퍼와 미세조류를 톨루엔에 각각 1분과 5분 동 안 노출한 뒤, Cellytics를 이용하여 로티퍼의 이동성과 미세조류의 형태 변화를 측정하여 독성을 평가하였다. 로티퍼의 이동성과 미세조류 의 형태변화는 모두 110.4 mg/L의 농도에서 대조군과 유의미한 차이를 나타내며(p<0.05), 이는 로티퍼의 생존율로 분석한 톨루엔의 LC50(552 mg/L)보다 낮은 농도였다. 본 연구에 따르면, 로티퍼와 미세조류를 전통적인 방식으로 최소 수 일 간 배양하여 얻을 수 있는 생 태독성평가 결과를 매우 짧은 시간(5분 이내)에 분석하고, 두 생물의 독성평가 결과를 신속하게 제공하여 현장에서 활용 가능한 신뢰성 높은 정보를 제공할 수 있음을 보여준다. 이는 독성평가를 이용하는 다양한 연구의 활용에 기여할 수 있으며, 환경보호 및 인체 건강 관 련 정책 수립에 도움이 될 것으로 기대된다.

Cnidium officinale M. is an important crop that is widely used as a raw material for health functional foods. However, it is experiencing cultivation difficulties due to climate change and abnormally high temperatures. In response to this problem, the characteristics and main causes of the high-temperature damage occurring in C. officinale M. cultivation fields were analyzed. A survey of five farmhouse fields in Jecheon and Bonghwa, major C. officinale M. cultivation areas in Korea in 2018, indicated that about 5% to 37% of the cultivation fields in Jecheon and 5% to 15% of the fields in Bonghwa died from wilting. The high-temperature damage of the C. officinale M. fields is divided into two categories: upper leaves drying due to solar radiation and temperature, and lower leaves dying serially to the radiant heat of the vinyl mulch. Damage caused by radiant heat was typically greater. This is due to the greenhouse effect that occurs in the small space between the black vinyl mulching and the soil. The heat radiated to the surface of the ridge creating an environmental condition that greatly exceeded the atmospheric temperature especially on hot days. As a result, short plants with underground parts, such as C. officinale M., can suffer more high-temperature damage than other plants, so it is considered that it is necessary to develop related technologies such as mulching materials that can reduce pavement temperature in the future.