본 연구는 LS-DYNA 971 을 이용하여 내빙 구조 선박과 빙산 모형 간의 충돌 시험을 수행 후 북극해 운항 선박의 내빙 능력을 분석하였다. 국제선급연합회(IACS)의 Unified Requirements for Polar ship(URI) 규정을 바탕으로 FEM 선박 모형에 내빙 구조를 적용하였으며, 빙산 모형에는 Elastic-perfect plastic 물성과 Tsai-Wu 항복 곡면을 적용하였다. 또한 실험 결과 비교를 위하여 내빙 구조를 갖추지 않은 일반 선박 모형과의 충돌 시험도 수행하였다. 실험 결과 일반 구조 선박의 구형 선수에 빙산 모형에 의해 움푹 들어간 약 1.8 미터 깊이의 선체 손상이 발생하였으나, 내빙 구조 선박의 충돌에서는 약 1.0 미터 깊이의 선체 손상만이 발생하였다. 또한 일반 구조 선박과 충돌한 빙산모형은 원형의 상태를 거의 유지한 반면, 내빙 구조 선박과 충돌한 빙산 모형은 내빙 구조의 구형 선수에 의해 빙산이 일부 파괴되는 현상이 발견되었다.
The effects of printed circuit board electroless nickel immersion gold (ENIG) and organic solderability preservative (OSP) surface finishes on the electromigration reliability and shear strength of Sn-3.5Ag Pb-free solder bump were systematically investigated. In-situ annealing tests were performed in a scanning electron microscope chamber at 130, 150, and 170˚C in order to investigate the growth kinetics of intermetallic compound (IMC). Electromigration lifetime and failure modes were investigated at 150˚C and 1.5×105A/cm2, while ball shear tests and failure mode analysis were conducted under the high-speed conditions from 10 mm/s to 3000 mm/s. The activation energy of ENIG and OSP surface finishes during annealing were evaluated as 0.84 eV and 0.94 eV, respectively. The solder bumps with ENIG surface finish showed longer electromigration lifetime than OSP surface finish. Shear strengths between ENIG and OSP were similar, and the shear energies decreased with increasing shear speed. Failure analysis showed that electrical and mechanical reliabilities were very closely related to the interfacial IMC stabilities.
This is a case reporL of a ra re mi xed odontogenic tumo r, amelob lastic fibro-odontoma in the poste1'ior of r ight ma nd tlbe A 2-year - olcl ma le pa ti enL was referred to our department ['or large tumorous lesion 011 ri ght mandible Radiograph ic examination s howed la rge radi opaque and rad iolu cent lesion with impacted and unerupted tooth, #44‘ #45 , #46 #85 , AJ'Ler s urgi cal enuclea Li on & cu rettage of t he mass , the tumor was confirmed to ameloblastic fibro-odontoma. lt was composed with c1 enta l orga ns a ncl is la nd of odontogeni c epithelium embedded in a cell - ri ch mesenchymal s troma, AIso‘ we ca rri ed out an immunohi stochemical study. The resul ts s howed positive CK7 staining. and showed weekly positi ve for Bcl - 2‘ Ki - 67 s Laining, while CEA, CK8‘ CKl2, CKl6 showed l1egative, Follow-up studies have shown no tumot recurrence for 2 yea rs ,
Background : Stevia rebaudiana (Asteraceae), a perennial plant, has been used as a low caloric sweetener and therapeutic agent for diabetes, hypertension, myocardial, and antimicrobial infections. It has been commonly used leaves and stems because of their high anti-oxidative potential. The present research was carried out to explore anti-oxidative and anti-melanogenic effects of aqueous extract of Stevia rebaudiana Bertoni flos in B16F10 cells.
Methods and Results : Anti-oxidant activity of Stevia flos extract (SFE) was determined by using 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging assay, nitric oxide (NO) radical scavenging method, and reducing power method. The results showed that the total phenolic content of SFE was 63.154 ± 0.0002 ㎍·QE/100㎎ and the total flavonoid was 8.64 1 ± 0.002 ㎍·GAE/100㎎. SFE exhibited a big significant effect on NO radical scavenging activity (IC50: 179.6 ㎍/㎖) comparing with standard ascorbic acid (IC50: 368.6 ㎍/㎖), and showed concentration dependent DPPH radical scavenging activity (IC50: 131.8 ㎍/㎖). Anti-melanogenic effect of SFE was also examined with B16F10 melanocytes. The amount of melanin synthesis followed by α-melanocyte stimulating hormone on B16F10 cells were significantly reduced in the presence of SFE treatment (p < 0.05). SFE also suppressed the tyrosinase activity (p < 0.05) and α-glucosidase activity (p < 0.05).
Conclusion : These results provide evidence Stevia rebaudiana flos has an antioxidant potency and can be used as an anti-melanogenic agent.