The effect of subcritical water for the extraction of total polyphenols and flavonoids from apple peel was investigated, and then the antioxidant activity of the extracts was estimated. Maximum yields of total polyphenolic compounds(36.4±1.9 mg quercetin equivalent(QE)/g dried material) and flavonoids(9.9±0.8 ㎎ QE/g dried material) were obtained by subcritical water extraction(SWE) with operating conditions of 190℃, 1, 300 psi, and 20 min. Furthermore, the highest antioxidant activity(76.1±1.1%) was observed in the extract obtained from SWE using the same conditions. The flavonoids from the SWE of apple peel were compared to three conventional extraction methods in terms of their extraction efficiency and antioxidant activity. The SWE was significantly more effective than hot water (90℃), methanol, and ethanol extraction for flavonoid yield by 4.7-, 2.2-, and 1.3-fold, respectively, and for antioxidant activity by 11.0-, 4.9, and 2.8-fold, respectively.

In the present study, we aimed to consider the name of twelve main Meridian in order to understand the concept of the Meridian system and to applicate acupuncture theory in the clinical field properly and fundamentally. We referred to several literatures on the matter and we found out that the name of present twelve Meridian was not settled until the period of Yellow Emperor's Classic. In the time of Yellow Emperor's Classic, the two theory of Internal Organ and Meridian system were combined and added new theory of ‘WoonGi'. The general rule of combination is that the component of name of Meridian consist of 'Hand' or 'Foot' , 'three Eum and Yang' and internal organ. The internal organ coupled with the root ki or middle ki of 'three Eum and Yang' and the 'Hand' or 'Foot' depend on the location of internal organ that belongs to meridian. The name of Twelve Meridian is a kind of system formed to analyze the two concepts organically and dynamically. One is material internal organ and the other is immaterial meridian system.

It is said that Dimentia is the state results in obstacle for work or social activity by decreased brain function. This study examined the causes, mechanisms, symptoms and theraphy for dimentia by comparing with references of Oriental & Westren medicine.

There are Governor Vessel(督脈), Conception Vessel(任脈), Thoroughfare Vessel(衝脈), Belt Vessel(帶脈), YIN Heel Vessel(陰蹻脈), Yang Heel Vessel(陽蹻脈), Yin Link Vessel(陰維脈) and Yang Link Vessel(陽維脈) in the category of the Eight Extra Channels. They keep the equilibrium state by controlling the unbalance between qi and blood(氣血), Yin and Yang(陰陽), and irrigate the Twelve Regular meridians(十二經脈). They are independent of the Twelve Regular meridians(channels) in running(流注), and, therefore, have their own running, and symptoms of disease. We have bibliographically studied the running, cross points, and symptoms of the Eight Extra meridians, and described the results as figures. By this study, we could confirm that the Eight Extra meridians have their own running, and symptoms of disease. We'll have to study further the application of this conclusion and the correlation between the Extra meridians(奇經) and the Regular meridians(正經).