Epidemic models on disease spread attempt to simulate disease transmission and associated control processes. This study reviewed published papers on epidemiological models for the management of foot-and-mouth disease in the world. In addition, an individual animal-based, spatially-explicit, stochastic disease transmission model, the Davis Animal Disease Simulation (DADS) model, was described in the frame of an international collaborative research project participating three countries: Republic of Korea, USA, and New Zealand. In this project, the Korean team is aiming at developing the most appropriate parameters for livestock and epidemiology of foot-and-mouth disease outbreaks. On the other hand, the purpose of foreign counterparts is validating their models: DADS (USA) and InterSpread Plus (New Zealand). Classification of farm types and preliminary estimations on the frequency of intra-herd contacts were also presented. This research project is expected to provide precious information to plan a strategy that will facilitate the eradication of foot-and-mouth disease from Korea.

Grossly, a lot of soft white nodules, 0.5～1.5 cm in diameter, were randomly scattered in liver of a slaughtered Korean Native Cattle. The surface of liver was roughened by those nodules. Histopathologically the nodules were consisted of numerous mature blood vessels, which had variable size and wall thickness, and which were encircled by much connective tissue. Masson's trichrome stain clearly revealed the proliferated blood vessels and perivascular stroma and, immunohistochemical staining revealed that endothelial cells of proliferated blood vessels were positive for Von Willebrand Factor. Based on gross and histopathological lesions, and immunohistochemical staining, the case was confirmed as hepatic vascular hamartoma and it is the first case report in Korea, as far as we know.

Toxocara (T.) canis, round worm of dogs and cats, is probably the most common gastrointestinal helminthes of domestic canid and is ascarid nematodes in the order Ascaridida, family Toxocaridae. The prevalence of patent toxocariasis is highest in the young dogs and much less common in adult dogs. There are few reports on the status of T. canis prevalence of dogs in Korea. Few cases of human visceral larva migrans also reported in Korea. However, as far as we know, there is no report on the canine toxocariasis case determined by pathological findings in Korea until now. In this research, we diagnosed canine toxocariasis by fecal egg test and pathologic findings in 2-month old two Pointer dogs. Typical T. canis eggs were detected in the fecal test. Numerous adult ascarids in the lumen of small intestine and stomach in one dog and multifocal white necrotic lesions in lung, liver, and kidney in another dog were observed grossly. Histologically, multifocal necrosis, eosinophilic inflammation and intralesional ascarid larva were prominent findings in the lung, liver and kidney.