본 연구는 뇌졸중 후 발생한 삼킴 장애 환자를 대상으로 목근육에 표면 전극을 이용한 전기 자극 치료가 삼킴 장애에 미치는 영향을 알아보고자 하였다. 연구방법 : 본 연구는 연세대학교 원주의과대학 부속 원주기독병원에서 뇌졸중으로 진단 받은 사람으로서 삼킴 장애가 비디오투시검사를 통해 확인된 18명을 대상으로 하였다. 자연회복 여부를 확인하기 위하여 2주 동안 삼 킴 장애 치료를 목적으로 한 어떠한 처치도 받지 않았고, 그 후 전기 자극 치료를 하루 1시간, 일주일에 5회, 4주간 실시하였다. 삼킴 기능의 변화를 알아보기 위하여 2주 통제 기간 전후와 전기 자극 치료 2주후, 전기 자 극 치료 4주 후에 비디오투시검사를 실시하여 각 대상자별 4회의 검사가 실시되었다. 녹화된 동영상을 바탕으 로 연하 곤란 척도와 인두 통과 시간을 측정하였다. 결과 : 대상자들은 통제기간동안 삼킴 기능의 변화가 없었지만(p>.05), 2주간의 전기 자극 치료 후 유의한 삼킴 기능의 향상을 보였으며(p<.05), 4주 전기 자극 치료 후에도 2주 전기 자극 치료 후보다 유의한 삼킴 기능의 향 상이 있었다(p<.05). 그러나 인두통과시간은 2주 치료 후, 4주 치료 후 모두 유의하게 변하지 않았다(p>.05). 삼 킴 후 인두기의 잔여물은 양배꼴동, 후두개곡에서 유의하게 줄어들었다(p<.05). 결론 : 본 연구 결과 대상자들은 2주 기간 동안 삼킴 기능의 자연 회복을 보이지 않았고 전기 자극 치료 후에 유의 한 기능 향상을 보여 전기 자극 치료의 효과를 증명하였다. 대상자들은 2주 전기 자극치료에서 뿐만 아니라 4주 치료 후에도 계속적인 기능 상승을 보였는데 앞으로는 본 연구보다 장기적인 치료의 효과와 이의 지속여부를 확 인하는 연구가 필요할 것으로 생각된다. 또한 인두통과시간은 삼킴 기능의 변화를 민감하게 나타내지 못하였으 므로 인두 통과 시간만을 측정하는 삼킴 기능의 평가는 추후 연구에서도 주의가 필요할 것으로 생각된다.

본 연구의 목적은 로봇의 상용화, 어플리케이션 개발에 대한 이해를 높이고 로봇의 평가 척도 간 연관성 및 개발 트렌드 등을 짚어보는 데 있었다. 인터랙티브 맵핑을 통해, 113가지의 로봇 샘플 자료들을 로봇의 평가척도 7가지에 대해 다양한 배치가 가능하고 각각 아이템에 대한 상세 정보가 참조 가능하도록 구현하여, 시각적으로 보다 면밀한 분석이 가능하였다. 또한 인터랙티브 맵핑을 활용하여 국가별 로봇 개발 성향의 차이를 살펴본 결과, 크게 미국, 유럽의 성향과 일본, 한국의 성향으로 나눌 수 있었다. 미국과 유럽은 공통적으로 로봇을 '도구'라 여기고, 이러한 점이 평가 척도의 다양한 부분에서 반영되었음을 알 수 있었다. 일본, 한국의 경우 로봇을 '파트너' 혹은 '공존하는 관계'라고 여기고, 이러한 점을 만족시키도록 개발하고 있는 것을 발견할 수 있었다.

Liquid crystalline phases were formed from acylglutamate; polyglyceryl-10 myristate and glycerine mixture and they were used as a base material for preparing an O/W emulsion. When an oil phase is added into the liquid crystalline phases, it was inserted into the dispersed liquid crystal droplets rather than stayed outside the liquid crystals, which can be known by the fact that the size of liquid crystal droplets increases with the increasing oil phase content. Along with the increase in the droplet size, the complex modulus increases from 100 to 350 pascals and the loss angle decreases from 60 to 24 degrees, from which it can be known that the increase in the internal phase volume results in the increase in the elastic property of oil in liquid crystalline-phases (O/LC). When the water phase was lastly added into the O/LC phase, the emulsification occurred to form a O/W emulsion and the averaged particle size of the O/W emulsion changes from 22.5nm to 538nm with the addition of water phase. The results from the droplet size measurements and stability tests under accelerated conditions such as high temperature show that the obtained O/W emulsion is very consistent with time.

Asymmetrical stance posture, balance, and gait disturbance are common problems in hemiplegic patients. Posterior leaf springs (PLS) are frequently prescribed to correct these problems. Recently, anterior leaf springs (ALS) have also been prescribed, but only limited studies have been performed to investigate the effects of ALS. The purpose of this study was to compare the effects of three conditions, i.e., wearing an ALS, wearing a PLS, and not wearing an AFO (ankle foot orthosis),: on 1) the distribution of weight bearing on the affected side, 2) standing balance, and 3) the gait patterns of hemiplegic patients. Eleven hemiplegic patients (10 men and 1 woman) participated in this study. The data were analyzed by the Friedman test. The results were as follows: 1) More weight bearing on the affected leg was observed in the ALS and PLS conditions than in the condition without an AFO. No significant difference between the ALS and PLS conditions was found. 2) There were statistically significant differences in the composite equilibrium scores (CES) among the three conditions. The CES in the PLS condition was significantly higher than in the ALS condition or the condition without an AFO. 3) Gait patterns improved significantly in the ALS and PLS conditions. No statistically significant difference between the ALS and PLS conditions was found. These results suggest that both ALS and PLS effectively improve the distribution of weight bearing on the affected side, standing balance, and gait patterns of hemiplegic patients. Further study using three-dimensional kinematic analysis and dynamic electromyography is needed to support these findings.

The purpose of this study was to determine the effect of lift to the shoe of the affected limb on gait patterns in subjects with hemiplegia. The subjects of this study were 18 post-stroke hemiplegics. For the study, insole of the paretic side was lifted 10mm higher, and duration of static weight bearing, dynamic weight bearing and stance phase were measured from one cycle of the gait, before and after the lift application. For the measurement of carry-over effect of lift, we got data of those three items prior to and 3 weeks after lift application and 3 days after removal of the lift. Static weight bearing was significantly increased both just after and continuous application of lift for 3 weeks than before. Dynamic weight bearing was significantly decreased in heel contact and footflat phases only when just after application of the lift, without any change after 3 weeks application. In heel-off phase, dynamic weight bearing did not show any significant difference between before and just after application of lift whereas significantly decreased after 3 weeks application. Duration of stance phase was not changed among anytime of application. According to this study, lift applied to the shoe of the peretic limb was effective in inducing static weight bearing in the paretic limb, but did not significantly effect dynamic weight bearing on gait patterns. This study suggests that symmetry, induced by shoe lift applied to the paretic limb, could help correct abnormal posture that would be caused in standing and prevent development of abnormal muscle tone in subjects with hemiplegia caused by unilateral stroke.

The purpose of this research was to determine the effects on the healing of fibular fractures in rabbits of low-intensity pulsed ultrasound (50 and 500 ) applied for periods of 4, 14 and 24 days following fibular osteotomy. Thirty-six male Japanese white rabbits were randomly divided into three groups of twelve for three treatment protocols: (1) ultrasound treatment at intensities of 50 and 500 until the 4th day following fibular osteotomy, (2) ultrasound treatment at intensities of 50 and 500 until the 14th day following fibular osteotomy, and (3) ultrasound treatment at intensities of 50 and 500 until the 24th day following fibular osteotomy. The low-intensity pulsed ultrasound was applied to only one fibula of each rabbit (these served as the experimental group). The other fibula of each rabbit served as the control group. The selection of which fibula was to be treated was made randomly. The animals were sacrificed on the 4th, 14th and 24th day after the start of ultrasound treatments. Percent of trabecular bone area and fibular radiography were carried out to compare the degree of fibular bone healing. A microscope was also used to determine any histologic changes. For statistical differences in radiological changes due to length of treatment period (4, 14 and 24 days respectively), the Wilcoxon signed-ranks test was used to compare the experimental and control groups. For statistical differences in fracture healing due to differences in ultrasound intensity, radiological studies were compared using the Mann-Whitney Test. And, to compute percentage differences in areas of trabecular bone, Two-way analysis of variance (ultrasound intensity x each group) was used. Experiment results were as follows: 1. In animals sacrificed on the 4th day, no difference was found in the radiological studies of the fibulae in the experimental and control groups (p>.05). However, experimental groups showed more rapid bone repair than control group. 2. Both radiographic and percent of trabecular bone area studies showed significant differences in rabbits sacrificed after 14 days. Fracture healing was significantly increased in the experimental group (p<.05) 3. In the animals sacrificed on the 24th day, histologic study showed rapid bone repair but fibular radiologic studies did not show statistical differences between the two groups (p>.05). 4. On the 14th day, bone union on radiograph was significantly more rapid in the treatment group with pulsed ultrasound of 50 than the group with 500 (p<.05). Histologic studies showed that both the 14 and 24 days groups had more rapid bone repair in animals treated with 50 ultrasound intensity than those treated with 500 intensity. In conclusion, it has been shown that the low-intensity pulsed ultrasound has a positive effect on bone fracture healing in the early stage and the range of pulse ultrasound from 50 to 500 is effective for fracture healing. Further study is needed to investigate the influence of pulsed ultrasound on delayed union and non-union in bone fractures and also for the clinical use of low-intensity pulsed ultrasound for bone healing in humans.

In rehabilitation programs involving muscle re-education and endurance exercise, it is necessary to confirm when fatigue occurs. It is also necessary to quantify fatigue, to confirm whether the muscle has been exercised sufficiently. In general, as fatigue occurs, the force-generating ability of the muscle is reduced. If the median frequency (MDF) obtained from electromyogram (EMG) power spectrum is correlated highly with work, then the timing and degree of fatigue may be confirmed. This study examined the relationship between work and MDF obtained from the EMG power spectrum during repetitive isokinetic exercise. Surface EMG signals were collected from biceps brachii and vastus lateralis of 52 normal subjects (26 males, 26 females) at and while performing an isokinetic exercise. The exercise was finished at 25% of peak work. MDF data was obtained using a moving fast Fourier transformation (FFT), and random noise was removed using the inverse FFT, then a new MDF data was obtained from the main signal. There was a high correlation between work and MDF during repetitiv isokinetic exercise in the biceps brachii and vastus lateralis of males and the biceps brachii of females (r=.50~.77). However, there was a low correlation between work and MDF in the vastus lateralis of females (r=.06~.19).

The purposes of this study were to investigate the therapeutic effects of an early exercise program after mastectomy and to provide the early exercise program protocol for patients who had undergone mastectomy. The subjects were seventy women who were diagnosed with breast cancer. They were randomly as signed either to a experimental group (n=35) that received early postoperative exercise program or to a control group (n=35) that received only education by nurses. Data were obtained for each patient from goniometric measurements of shoulder flexion, abduction, external rotation, 10 elements of functional performance, and subjective pain evaluation using visual analogue scale (VAS). All variables were measured preoperatively, three days postoperatively, and one month postoperatively. Data were compared by groups using independent t-test and Mann-Whitney U test for parametric or non-parametric data, respectively. There were no significant differences between the groups for all variables preoperatively and at three days postoperatively. But there were significant differences at one month postoperatively. The experimental group showed a statistically significant increases in shoulder flexion, abduction, and external rotation and in the pain VAS at one month postoperatively (p<.05). Also, at one month postoperatively, the experimental group had less difficulty with three elements of functional performance-doing up a 'back' zippered article of clothing, reaching the ipsilateral scapula, and contralateral scapula with the fingers on the operated side-than the control group (p<.05). The results of this study suggest that, after mastectomy, the early exercise program conducted by a well-trained physical therapist can make a significant contribution to the return of more normal shoulder function and activities of daily living and to an increased quality of life.

The purpose of this study was to establish modified physiological cost index (PCI) for predicting energy consumption by heart rate (HR) at isokinetic ergometer exercise testing. The subjects were twenty-eight healthy men in their twenties. All of them performed upper and lower extremity isokinetic ergometer exercise tests which had six loads (400, 500, 600, 700, 800, and 900 kg-m/min) and five loads (400, 500, 600, 700, and 800 kg-m/min) respectively. The exercise sessions were finished when HR was in plateau. HR and oxygen consumption were determined during the final minute. Resting heart rate and oxygen consumption were used for calculating heart rate, oxygen consumption changes and modified PCI. Regression analysis established the relationship between each variable to work load, HR and oxygen consumption. The results were as follows: 1) In the lower extremity ergometer exercise test, oxygen consumption increased continuously as work load increased, but in the upper extremity ergometer test, oxygen consumption only increased until work load was 700 kg-m/min. 2) HR increased as work load increased in both exercise tests, but in the upper extremity ergometer test, HR decreased from the 700 kg-m/min. 3) The modified PCI increased as work load mcreased until the 700 kg-m/min point in the lower extremity ergometer test and until the 500 kg-m/min point in the upper extremity ergometer test when it started to decrease in both tests. 4) In the lower extremity ergometer exercise test, regression analysis established the relation as = -.0215HR - .2141 where is given in l/min and HR in beat/min ( = .2677, p = .000). ln the upper extremity ergometer exercise test. regression analysis established the relation as = -.0115HR + .2746 ( = .1308, p = .000). The results of this study were similar to previous studies but were different under high work load conditions. So modified PCI should be used with only low intensity work load testing. Subjects for upper extremity ergometer exercise testing should complete a prescribed training course prior to testing, and only low intensity work load should be used for safety considerations.

Many children with physical disability have feeding difficulties. In cases of children with cerebral palsy, feeding difficulties can be seen in abnormal oral motor activity and defective swallowing coo rdination. These problems originate from neurological lesions. The purpose of this study was to i nvestigate the effect of trunk and neck position on the following aspects of swallowing: stages of oral preparation, pharyngeal swallowing reflex, pharyngeal clearing and aspiration. Sixteen subjects with quadriplegic cerebral palsy were examined to assess their swal-lowing abil ity using videofluoroscopy(VFS). Subjects were evaluated in four different positions 1) trunk erect with the neck flexed 30°2) trunk reclined 30°posteriorly with the eck positioned neutrally 3) trunk re clined 30°posteriorly with the neck flexed 30° 4) trunk in supine with the neck flexed 30°. Friedman's test was used to analyze the effect of posi tion of the neck and trunk on swallowing. The results were as follows: 1. Ability of oral preparation was significantly better with the subject's trunk recli-ned 30°poste riorly and the neck flexed 30°than with the trunk erect and the neck flexed 30°(p < 0.05). 2. Ability of pharyngeal clearing was significantly better with the subject's trunk er-ect and the neck flexed 30° than in supine with the neck flexed 30°(p < 0.05). 3. Incidence of swallowing reflex was not significantly different among the four posi- tions (p > 0.05). 4. Prevention of aspiration was significantly better with the subject's trunk reclined 30°posteriorl y and the neck flexed 30° than with the trunk reclined 30°posteriorly and the neck neutrally positi oned or in supine with the neck flexed 30°(p < 0.05). These results suggest that positions of both the neck and the trunk have an effect on swallowi ng in children with cerebral palsy. The position with the trunk reclined 30°posteriorly and the n eck flexed 30°was found to be optimal for oral preparation and prevention of aspiration. Further r esearch to study swallowing ability in conjunc- tion with respiratory function is indicated.

아스코빅애씨드(비타민 C)는 스킨 케어 조성물에 널리 사용되어 왔다. 아스코빅애씨드는 항산화, 콜라겐 생합성 촉진, 피부미백효과 등 특별한 효과를 나타내며, 안티-에이징 활성성분으로 사용되고 있다. 하지만, 화장 료 조성물에서는 아스코빅애씨드의 산화, 갈변, 변취와 같은 불안정한 문제가 있어 높은 함량을 적용하기에는 문제가 많다. 우리는 폴리올을 사용하여 아스코빅애씨드를 녹인 무수제형 조성물로 안정화를 진행했다. 무수제 형은 아스코빅애씨드의 산화를 효과적으로 억제할 수 있는 조성물이다. 하지만, 5 ℃ 이하의 온도 조건일 때 무 수제형 내에서 결정화가 일어나는 문제점이 있다. 우리는 수계에 아스코빅애씨드를 안정화하여 결정화 문제를 해결하고자 하였다. 본 연구에서는, 징크설페이트, 글루타치온, 강황뿌리추출물과 같은 항산화제를 사용하여 아 스코빅애씨드를 안정화할 수 있는 최적의 비율을 찾고자 하였다. 조성물은 – 16 ℃, 5 ℃, 25 ℃, 40 ℃, 50 ℃ and cycle(5 – 40 ℃) 인큐베이터를 사용하여 8주에 걸쳐 안정도를 확인하였다. 안정성 분석은 색상, 향, 상 분리, 침강 정도를 검토하였다. 아스코빅애씨드의 안정성은 HPLC 분석을 통하여 확인하였다.

Mt. Deoktaesan(1,113 m) is located in Jinan-gun Baekun-myon and Jangsu-gun Chunchun-myon. Investigated area was decided to include Mt. Deoktaesan, Mt. Seongaksan and its neighbor area, and this study was conducted from March to October, 2015 in 12 days. Based on the voucher, vascular plants in Mt. Deoktaesan were 108 families 341 genera 525 species 4 subspecies 64 varieties 14 forms, totally 607 taxa, which is 12.4% of total Korean flora. Korean endemic plants were 15 species. Among these species, Populus tomentiglandulosa T.B.Lee, Campanula takesimana Nakai and Forsythia koreana (Rehder) Nakai are verified as planted species. Rare and endangered plants of designated by Korea Forest Service were 10 taxa, such as Peucedanum hakuunense Nakai, Paeonia japonica (Makino) Miyabe & Takeda, Koelreuteria paniculata Laxmann, Eranthis stellata Maxim., Eranthis stellata Maxim., Viola albida Palib., Chionanthus retusus Lindl. & Paxton, Campanula takesimana Nakai, Tricyrtis macropoda Miq. and Iris ensata var. spontanea (Makino) Nakai, respectively. Phytogeographical special plants were totally 41 taxa, which were grade 17 taxa of garde I, 12 taxa of grade Ⅱ, 12 taxa of grade Ⅲ, 8 taxa of grade Ⅳ, and 1 taxon of grade Ⅴ.