In recent years, there has been an increase in the morbidity of gastritis in Korea due to lifestyle factors mostly changes in eating habits and stress. Gastritis is more likely to progress to gastric cancer, and therefore it is important to prevent and manage gastritis through lifestyle adjustment and treatment at an early stage. In this study, cabbage, which was found to be effective in gastritis, was mixed and fermented with other crucifer plants such as kale and broccoli to evaluate the overall efficacy of fermented brassica puree on alcoholic acute gastritis. Based on our results, fermented brassica puree alleviated gastric injury induced by 150 mM HCl/60% ethanol. In addition, it was confirmed that PGE2, a gastric mucosal protective factor, was increased, and other positive effects such as an increase of MUC1 and regulation of PKC were observed. The results of this study suggest that fermented brassica puree can relieve acute alcoholic gastritis by regulating PGE and the expression of MUC1, a gene related to mucus secretion, and activating PKC, which is related to mucosal cell activity.

Probiotics improve the immune system. However, the effects of its lactic acid bacteria on atopic dermatitis relief and inflammation improvement is not fully understood. Recently, one of the probiotics, Lactobacillus helveticus HY7801 (HY7801), was found to have an anti-inflammatory effect. In this study, we investigated the effects of HY7801 on atopic dermatitis-induced animal models. After four weeks of oral administration, the group treated with HY7801 showed amelioration of the atopic dermatitis compared to the group receiving placebo. In the HY7801 treated group, the epidermal hyper-proliferation and collagen deposition were inhibited compared to the placebo group, and the secretion amount of the inflammatory factors, such as TNF-α, IL-4 were reduced. In conclusion, these results suggest that HY7801 acts as a functional probiotic via amelioration of the atopic dermatitis such as a decrease of epidermal hyper-proliferation, and collagen deposition and anti-inflammatory effects.

축산 관련 작업 시 미세분진, 곰팡이, 세균, 가축의 배설물 등, 축사현장 환경여건이 작업자에게 위해한 영향을 미칠 우려가 있어 본 연구에서는 인수공통질병(병원성 대장 균, 살모넬라균 등)과 동물 병원성 바이러스 등에 의한 질병의 방역, 살처분 작업현장 및 축산업 종사자들이 사용하는 1회용 피복제로 외부로부터 인체 내로 접촉 또는 침투 되는 입자상물질(aerosol, particle, virus)과 방역 시 사용되는 액상 및 입자상 소독약 품의 유해화학물질(글루타르 알데히드, 구연산, 복합염류, 탄산소다, 가성소다) 감염예 방 및 생물학적 위해요인으로부터 보호하기 위한 내수도, 투습도, 내화학 특성이 우수한 PTFE membrane 복합 방역보호복 개발하고자 한다. 방역보호복 제품 3종을 실험 결과 병원성대장균 E. coli 0157에서는 PTFE 복합원단이 99.999%이상, 시험군인 국 내제품은 99.996%, 수입제품은 99.999%로 시험군보다 PTFE 복합원단이 99.999%이 상 병원성대장균을 Capturing하는 결과를 보였고. S. gallinarium에서는 PTFE 복합원 단이 99.999%이상, 시험군인 국내제품은 99.997%, 수입제품은 99.999%로 시험군보 다 PTFE 복합원단이 99.999% 병원성대장균을 Capturing하는 결과를 보였으며 S. typhimurium에서는 PTFE 복합원단이 99.999%이상, 시험군인 국내제품은 99.996%, 수입제품은 99.995%로 시험군보다 PTFE 복합원단이 99.999%이상 병원성대장균을 Capturing하는 결과를 보였다. 원충2종 실험에서 Eimeria coccidium과 Toxoplasma gondii에서는 PTFE 복합원단이 99.999%이상, 시험군인 국내제품은 99.999%이상, 수 입제품은 99.999%이상으로 PTFE 복합원단과 국내제품, 수입제품 모두가 99.999%이 상 원충을 Capturing하는 결과를 보였다. 마지막으로 Influenza virus A 실험에서는 PTFE 복합원단이 99.999%이상, 시험군인 국내제품은 99.944%, 수입제품은 99.937%로 시험군보다 PTFE 복합원단이 99.999%이상 바이러스를 Capturing하는 결 과를 보였다. 본 실험결과 개발제품인 PTFE membrane 복합 방역보호복 소재가 병원 성바이러스 3종과, 원충 2종, 바이러스가 보호복에 붙었을 경우, 특수한 결합에 의해 보호복이 병원균을 잡아주는 역할을 하여 2차 감염을 예방하는 효과가 있는 것을 확인하였다.

The anti-diabetes mechanism of silkworm Bombyx mori L. powder and extracts was found to inhibit the activity of α-glycosidase. The major functional component of silkworm powder was 1-deoxynojirimycin (1-DNJ), which exerts a blood glucose-lowering effect. In this study, we aimed to compare the effects of the supplements, including red ginseng extract on the functional components of silkworm. Fifty silkworm larvae were divided into the control group (Con, N=50), group A (A, artificial diet 95% and mulberry leaf powder 5%), group B (B, artificial diet 95% and mulberry powder 5%), group C (C, artificial diet 95% and Rubus coreanus remainders 5%), group D (D, artificial diet 95% and red ginseng extract 5%), and group E (E, artificial diet 95% and yeast powder (Saccharomyces cerevisiae). Body weights and length of silkworm larvae showed significant improvement in group A, D. In particular, the growth rate in group D (artificial diet 95% and red ginseng extract 5%) was larger than that of Con. In addition, the results showed that 1-DNJ concentration was significantly largest in group D. From these results, it is concluded that the addition of red ginseng extract may be effective for larval growth and 1-DNJ accumulation in silkworm rearing with an artificial diet.