In Korea, two types of spent nuclear fuels (SNFs) are generated, pressurized light water reactor type (PWR) and pressurized heavy water reactor type (PHWR; CANDU), that differ greatly in size, decay heat, and radioactive characteristics. Technology development for the disposal of SNFs has mainly focused on PWR SNFs that are large in size and have extremely high decay heat and radioactivity. However, CANDU SNFs should be considered differently from PWR SNFs in deep geological disposal systems because their characteristics significantly differ from those of PWR SNFs in terms of their dimensions, number of SNF bundles, and handling systems in nuclear power plant sites. In this paper, after reviewing the status of the CANDU SNF disposal concept by Canada and Korea, concepts related to the direct geological disposal of CANDU SNFs were described, and two concepts were proposed based on the results of the development. The engineered barrier systems developed using these two concepts were comparatively analyzed in terms of disposal safety, disposal efficiency, and technical maturity. Based on the results of the comparative analyses, a vertical-type emplacement disposal concept was determined as a reference concept for the deep geological disposal of CANDU SNFs.
Considering the various health problems associated with obesity in dogs, including renal diseases, joint disorders, and skin diseases, effective management strategies and guidelines are urgently needed. This situation has led to a growing demand for veterinary medications aimed at addressing obesity in dogs. However, the field faces a significant hurdle due to the absence of standardized guidelines for assessing the effectiveness of these anti-obesity medications in dogs. In response to this gap, the Animal and Plant Quarantine Agency (APQA) in Korea has made a crucial step by introducing clinical trial guidelines to evaluate the efficacy of treatments for canine obesity, specifically aimed at approving veterinary medicinal products. The guidelines outlined the selection criteria for target dogs, highlighting the importance of consistency within the control and treated groups. Treatment efficacy is subsequently evaluated by physical examination, body fat reduction, and biochemical indicators. In addition, the guidelines cover dosage and administration, monitoring after dosing, and statistical analysis. By doing so, this guideline not only highlights the significance of the APQA’s initiative in improving the care of obese dogs but also provides practical insights to enhance the standardization and effectiveness of clinical trials in veterinary medicine.
본 연구는 작약의 품종간 개화시기 차이와 저온에서 장기 저 장이 가능한 품종을 선발하여 절화 유통 기간을 연장하기 위하 여 수행하였다. 작약 24품종을 대상으로 2022년 국립원예특작 과학원 시험포장에서 개화시기와 절화 품질을 조사하였다. 봉오 리 상태에서 수확한 작약을 건조 저장법으로 -1℃에서 60일 저장한 후 절화 수명과 절화품질을 조사하였다. ‘의성작약’은 홑 꽃이었고 나머지 품종은 겹꽃이었다. 개화시기는 5월 10일부터 18일 사이였으며, ‘Etched Salmon’, ‘Monsieur Jules Elie’, ‘Gilbert’, ‘Henry Bockstoce’는 개화일이 5월 10일로 가장 빨랐고, ‘Elsa Sass’는 5월 18일로 가장 늦었다. 식물체 키는 74.6∼107.8cm 였고, 절화 무게는 ‘Henry Bockstoce’ 품종 이 89.8g으로 가장 무거웠고, ‘Angel Cheeks’ 품종이 26.7g으 로 가장 가벼웠다. 꽃의 주된 색은 흰색, 빨강색, 분홍색, 자주색 이었다. -1℃에서 60일간 저장 후에 꽃과 잎의 상태가 아주 양 호한 품종은 ‘Kansas’, ‘Ole Faithful’, ‘Sonw Mountain’이 었다. 절화수명은 ‘Nick Shaylor’ 품종이 8일로 가장 길었고, 다음으로 ‘Blush Queen’, ‘Elsa Sass’ 품종이 7일이었으며, ‘Gilbert’, ‘Highlight’ 품종이 1일로 가장 짧았다. 작약은 저온 장기 저장에서 일부 품종을 제외하고는 꽃과 잎에 저온장해 증 상이 발생하였다. 이와같은 결과는 작약재배시에 품종 선택과 수확후 저온 장기 저장을 통하여 유통기간을 연장하고 하고자 할 때 기초자료로 활용될 수 있을 것으로 기대된다.
The diversity of smart EV(electric vehicle)-related industries is increasing due to the growth of battery-based eco-friendly electric vehicle component material technology, and labor-intensive industries such as logistics, manufacturing, food, agriculture, and service have invested in and studied automation for a long time. Accordingly, various types of robots such as autonomous mobile robots and collaborative robots are being utilized for each process to improve industrial engineering such as optimization, productivity management, and work management. The technology that should accompany this unmanned automobile industry is unmanned automatic charging technology, and if autonomous mobile robots are manually charged, the utility of autonomous mobile robots will not be maximized. In this paper, we conducted a study on the technology of unmanned charging of autonomous mobile robots using charging terminal docking and undocking technology using an unmanned charging system composed of hardware such as a monocular camera, multi-joint robot, gripper, and server. In an experiment to evaluate the performance of the system, the average charging terminal recognition rate was 98%, and the average charging terminal recognition speed was 0.0099 seconds. In addition, an experiment was conducted to evaluate the docking and undocking success rate of the charging terminal, and the experimental results showed an average success rate of 99%.
Periodontal disease (PD) is strongly linked to increased risk of oral squamous cell carcinoma (OSCC); however, the specific mechanism through which the development of PD and OSCC is simultaneously promoted remains unclear. This study explored the impact of periodontal pathogens on OSCC progression and the contribution of periodontal pathogen-stimulated OSCC to PD development. The expression of osteoclastogenesis-inducing factors was assessed using quantitative reverse transcription polymerase chain reaction analysis following stimulation of OSCC with lipopolysaccharide (LPS) derived from the periodontal pathogen Porphyromonas gingivalis (Pg), a pathogen commonly responsible for PD. The cell counting kit-8 assay was used to determine the effects of Pg-LPS on OSCC proliferation and drug resistance to cisplatin and 5-fluorouracil. The effects of conditioned medium (CM) derived from Pg-LPS–stimulated OSCC on osteoclastogenesis was evaluated using tartrate-resistant acid phosphatase (TRAP) staining on bone marrow-derived macrophages (BMMs). Pg-LPS administration in SCC-25 and YD-8 OSCC cell lines induced a significant increase in receptor activator of nuclear factor kappa-B ligand mRNA expression; however, it did not affect cell proliferation. Treatment with CM derived from Pg-LPS–stimulated SCC-25 or YD-8 cells markedly enhanced the formation of TRAP-positive multinucleated cells during osteoclast differentiation of BMMs. Altogether, these findings demonstrate that Pg-LPS–stimulated OSCC promoted osteoclastogenesis through a paracrine mechanism.
국제해사기구는 국제해운의 온실가스 배출을 줄이기 위한 전략을 채택하였으며, 선박 기인 온실가스 배출을 줄이기 위해 보다 강화된 목표를 설정하고 있다. 액체수소를 기화시켜 연료로 사용하는 고분자 전해질 연료전지는 이러한 규제를 준수하기 위한 유망한 기 술 중 하나로 평가받고 있다. 일반적으로 선박시스템 설계는 선급의 규정에 따라야 하지만 환경규제가 강화됨에 따라 새로운 연료와 시 스템의 도입이 가속화되고 있으며, 이로 인해 규정개발이 기술의 도입을 따라가지 못하는 경우도 발생하고 있다. 이러한 격차를 해소하기 위해, 본 연구에서는 수소 연료가스공급 시스템을 대상으로 위험요소 및 운전분석 기법(HAZOP)과 보호계층분석 기법(LOPA)을 결합하여 신기술의 안전성을 검증하는 방법을 제시하였다. 먼저 HAZOP을 통해 위험 시나리오를 식별하고, LOPA를 통해 정성적인 HAZOP 결과를 정량적으로 보완하였다. 초기사건의 빈도와 독립보호계층(IPL)들의 작동 요구시 고장 확률(PFD)을 계산하였다. 기존 IPL의 적절성을 결정 하기 위해, 예상되는 완화 정도를 가정한 허용기준과 비교하였으며, 필요한 경우, 추가 IPL을 권장하였다. 본 연구를 통해서 HAZOP-LOPA 기법이 조선해양 분야에서 신기술의 안전성을 평가할 수 있는 잠재력을 가지고 있음을 확인하였다.
Hangovers, resulting from excessive alcohol intake, manifest hours after drinking, causing symptoms like thirst, headache, and fatigue. Alcohol is metabolized in the liver by alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), with acetaldehyde and reactive oxygen species contributing to toxic effects. Morning Care (MC) products were evaluated in male and female mice to assess their impact on alcohol metabolism and hangover alleviation. The study revealed that pre-administration of MC products led to a significant reduction in blood ethanol and acetaldehyde concentrations postalcohol ingestion. This remarkable finding suggests a potential breakthrough in hangover relief. Enhanced ADH and ALDH activities were observed in blood and liver samples, indicating improved alcohol metabolism. Interestingly, gene expression levels of ADH and ALDH in the liver did not show significant differences, suggesting that MC products likely enhance enzyme activities through post-translational modifications rather than altering gene expression. These findings underscore the potential of MC products to mitigate hangover symptoms by enhancing alcohol metabolism.
Line observations of young stellar objects (YSOs) at (sub)millimeter wavelengths provide essential information of gas kinematics in star and planet forming environments. For Class 0 and I YSOs, identification of Keplerian rotation is of particular interest, because it reveals presence of rotationally-supported disks that are still being embedded in infalling envelopes and enables us to dynamically measure the protostellar mass. We have developed a python library SLAM (Spectral Line Analysis/Modeling) with a primary focus on analyses of emission line data at (sub)millimeter wavelengths. Here, we present an overview of the pvanalysis tool from SLAM, which is designed to identify Keplerian rotation of a disk and measure the dynamical mass of a central object using a position-velocity (PV) diagram of emission line data. The advantage of this tool is that it analyzes observational features of given data and thus requires few computational time and parameter assumptions, in contrast to detailed radiative transfer modelings. In this article, we introduce the basic concept and usage of this tool, present an application to observational data, and discuss remaining caveats.
Electrochemical water splitting presents an optimal approach for generating hydrogen ( H2), a highly promising alternative energy source. Nevertheless, the slow kinetics of the electrochemical oxygen evolution reaction (OER) and the exorbitant cost, limited availability, and susceptibility to oxidation of noble metal-based electrocatalysts have compelled scientists to investigate cost-effective and efficient electrocatalysts. Bimetallic nanostructured materials have been demonstrated to exhibit improved catalytic performances for the oxygen evolution reaction (OER). Herein, we report carbon aerogel (CA) decorated with different molar ratios of Fe and Ni with enhanced OER activity. Microwave irradiation was involved as a novel strategy during the synthesis process. Inductively coupled plasma mass spectrometry (ICP-MS), X-ray diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS), Scanning Electron Microscope (SEM), Energy dispersive X-ray spectroscopy (EDAX spectra and EDAX mapping), Transmission Electron Microscope (TEM), High-Resolution Transmission Electron Microscope (HR-TEM), and Selected Area Electron Diffraction (SAED) were used for physical characterizations of as-prepared material. Electrochemical potential towards OER was examined through cyclic voltammetry (CV), chronoamperometry, and electrochemical impedance spectroscopy (EIS). The FeNi/CA with optimized molar ratios exhibits low overpotential 377 mV at 10 mAcm− 2, smaller Tafel slope (94.5 mV dec− 1), and high turnover frequency (1.09 s− 1 at 300 mV). Other electrocatalytic parameters were also calculated and compared with previously reported OER catalysts. Additionally, chronoamperometric studies confirmed excellent electrochemical stability, as the OER activity shows minimal change even after a stability test lasting 3600 s. Moreover, the bimetallic (Fe and Ni) carbon aerogel exhibits faster catalytic kinetics and higher conductivity than the monometallic (Fe), which was observed through EIS investigation. This research opens up possibilities for utilizing bi- or multi-metallic anchored carbon aerogel with high conductivities and exceptional electrocatalytic performances in electrochemical energy conversion.
Chlorine is a crucial radionuclide that must be removed in irradiated nuclear graphite. Understanding the interaction between chlorine and graphene-based materials is essential for studying the removal process of 36Cl from irradiated nuclear graphite. In this study, first-principle density functional theory (DFT) was utilized to investigate the adsorption characteristic of chlorine on the original and reconstructed edges of graphene-based materials. Based on the calculation of adsorption energy of the structures after each step of adsorption, the most energetically favorable adsorption routes at four types of edge were determined: Along the armchair edge and reconstructed zigzag edge, the following adatoms would be adsorbed to compensate the distortion induced by the previously adsorbed atom. Meanwhile at the original zigzag edge, chlorine atoms would be adsorbed alternatively along the edge to minimize the repulsion between two adjacent chlorine atoms. The chemical nature of the bonds formed as a result of adsorption was elucidated through an examination of the density of states (DOS) for the two adsorbed chlorine atoms and the carbon atoms attached. Furthermore, to assess the relative stability of the adsorption structures, formation energy of all energetically favorable structures following adsorption was computed. Consequently, the predominant adsorption structure was identified as the reconstructed armchair edge with two chlorine atoms adsorbed. The desorption process of 36Cl2 from the predominant structure following adsorption was simulated, revealing an energy barrier of 1.14 V for desorption. Comparison with experimental results suggests that the chlorine removed from reconstructed armchair edges significantly contributes to the low-temperature removal stage of 36Cl from irradiated nuclear graphite.
The study investigated the influence of website features on the purchase intention of online fashion among Generation Z consumers in South Africa. This topic has received increasing attention against the backdrop of the rapidly growing ‘Digital Generation’, or ‘Millennial consumers’, who are one of the most tech-savvy generations. Despite the benefits that online shopping offers to both the business and the consumer, the act of buying clothes online has presented some challenges to customers. This study therefore aims to gather further insight in an attempt to provide fashion businesses with guidance to better succeed in encouraging customers to shop online. This study selected two visual elements (website aesthetics and product presentation) and two functional website features (website navigation, and security and privacy) and social norms, the test the effect they have on perceived ease of use, attitude and intention to purchase clothing online. The proposed conceptual model tested seven hypotheses of which four were supported. By means of an empirical study, 166 online surveys were collected from individuals within the Generation Z cohort and the analysis was done using SPSS27 by running multiple regression analysis to test the relationships between the variables. The results from this study provide global and local fashion brands with valuable insight into the consumption habits of young consumers in an emerging economy, and factors that drive online fashion consumption.