Korea Atomic Energy Research Institute’s Post Irradiated Examination Facility safely stores spent nuclear fuel using a wet storage method to conduct research. Here, in order to remove the radioactivity released into the water, the stored water is passed through an ion exchange resin tower, and the radionuclides are exchanged with the bead-shaped ion exchange resin filled inside to lower the radioactivity concentration. At this time, because the stored water passes in one direction, clogging of the ion exchange resin occurs. If this phenomenon continues, the flow rate of the water treatment process decreases and operation efficiency decreases, so a backwashing process is necessary to re-mix the ion exchange resin and secure the flow rate again. In this study, the flow rate reduction trend according to the lifespan of the ion exchange resin and the flow rate recovery according to the backwash process operation amount were analyzed. The flow rate reduction trend of the ion exchange process was analyzed immediately after the backwashing process was started. In addition, the amount of flow recovery according to the backwash process operation amount was evaluated by the amount of waste generated during the backwash process and the number of days of operation until the backwash process was needed again. As a result, the flow rate of the ion exchange process decreased rapidly right after the backwash process until the position of the ion exchange resins was stabilized, and then stabilized. After that, it gradually decreased and reached the point where the backwash process was necessary. However, the decline trend was analyzed to be the same regardless of the lifespan of the ion exchange resin. In addition, the amount of waste generated during the operation of the backwash process was increased in the order of 400 L, 600 L, 1,100 L, 1,400 L, 3,500 L, and 4,200 L to increase the amount of operation of the backwash process. As a result, the number of days of ion exchange resin operation was 285 days, 338 days, and 342 days, was analyzed as 422 days, 322 days, and 720 days. Based on this study, it was confirmed that the flow rate reduction trend is the same regardless of the lifespan of the ion exchange resin, and as the backwash process operation increases, the number of days the ion exchange process can be operated increases, but there is a turning point where the waste treatment cost exceeds the number of days of operation.

Understanding the dispersion of xenon isotopes following a nuclear test is critical for global security and falls within the remit of both the Comprehensive Nuclear-Test-Ban Treaty (CTBT) and the International Noble Gas Experiment (INGE). This paper aims to show if it is possible to discriminate the source of xenon releases based on the atmospheric dispersion of xenon isotopes using HYSPLIT. Using ORIGEN and SERPENT simulations, four released scenarios are defined with four different fractionation times (i.e., 1 hour, 1 day, 10 days, and 30 days) after a 1kt TNT equivalent 235U explosion event. These time-delayed release scenarios were selected to certify the possibility of mis-determining xenon release source. We use the Lagrangian dispersion model for atmospheric dispersion to predict the concentration distribution of xenon isotopes under each scenario. The model allows us to better understand how these isotopes would distribute over time and space, offering valuable data for real-world detection efforts. To our knowledge, there have been no researches on the analysis of xenon isotopic ratios considering atmospheric dispersion. In this work, we focused on the atmospheric dispersion using HYSPLIT to characterize the xenon isotopic ratios from nuclear tests. In addition, we compared the xenon isotopic ratios obtained from the atmospheric dispersion with those from ORIGEN calculations, which would be helpful to discriminate the source of the xenon releases.

Companies are paying attention to project governance to realize their goal strategies, project success, and project value in a rapid and complex environment due to the development of information technology. This study aims to explore project governance and factors from literature review and practice guides related to project governance and empirically analyze the impact of project governance factors on IT project objective performance. The survey was conducted on project managers, project team members, and project management members with experience in carrying out business IT projects within two years at companies in various industries in Korea. The main conclusion is as follows. Among the project governance factors, disclosure and reporting that uses and reports using appropriate and reliable information about projects related to decision-making activities positively impact the achievement of IT project objectives: business success and stakeholder satisfaction. Among the project governance factors, project sponsorship, a role that effectively connects management and projects, and a project management framework that provides tools, procedures, resources, and techniques for projects positively impact IT project objective performance. This study is of academic and practical significance in that it identifies the definition and factors of project governance through companies in various industries in Korea and the positive impact of project governance factors on IT project objective performance.

Technology innovation companies are focusing on contributing to business performance by R&D project as a strategic tool. Successful R&D leads to corporate competitiveness enhancement, national industrial development, but there are high uncertainty and risks in R&D. Public and private R&D projects are carried out to achieve various purposes. It was verified how the risk management and benefit management of the R&D project affect the detailed R&D project performance between the Public and private domain. The impact of Project Leadership on R&D performance was also analyzed. Those who have participated in the Public and Private R&D projects at companies or research institutes were surveyed. First, it was found that project risk and benefit management have partially an effect on R&D project performance. Second, Public and private R&D Project Leadership showed partially a interaction effect between project management and project performance.

본 연구는 절화 도·소매업자의 판매 행태, 소비자의 소비 행태와 수입산 절화 및 국내산 절화 인식을 조사하여 국내산 절화 경쟁력 강화를 위한 자료로 제공하고자 수행하였다. 설 문 조사는 도·소매업자 102명을 대상으로 2020년 7월부터 9 월까지 진행하였고, 소비자는 200명을 대상으로 2020년 8월 24일부터 25일까지 진행하였으며, 수집된 자료는 빈도 분석, 대응표본 t-test, 다중반응 교차분석을 실시하였다. 도·소매업 자의 판매 행태 조사 결과, 국내산과 수입산 절화 모두 판매하 고 있는 비율이 높았고 판매 시 국내산 절화의 품질보다 수입 산 절화의 품질이 우수하다고 응답하였다. 소비자의 구매 행 태 조사 결과, 주로 선물 목적으로 구매하며 구매 시 내적 품 질(수명)과 외적 품질(형태, 질감, 색상)을 중요시 여기는 것으 로 나타났다. 또한 소비자는 절화 구입 시 원산지를 확인하지 않는 경우가 많았으나 동일 품종일 경우 국내산을 구매한다고 응답하였다. 도·소매업자와 소비자의 절화 인식을 비교한 결 과, 도·소매업자는 국내산 절화가 평범하고 한정적이며, 수입 산 절화는 독특하다고 인식하였으나, 소비자는 국내산 절화가 독특하지만 수입산 절화와 국내산 절화 모두에 평범하고 한정 적이라고 인식하였다. 이러한 판매자와 소비자간 인식 차이는 실제 국가별 절화 품질에 대한 정량적 연구와 국가별 절화에 대한 인식 조사 필요성을 제기한다.

White rot fungus Cerrena unicolor IUM 5400 produced ethanol from diverse sugars, including glucose, mannose, galactose, and cellobiose at 0.38, 0.28, 0.08, and 0.27 g of ethanol per g of sugar consumed, respectively. The fungus produced relatively high amounts of ethanol from xylose (0.28 g of ethanol per g of sugar consumed); however, the ethanol conversion rate of arabinose was relatively low (at 0.08 g of ethanol per g sugar consumed). When cultured in a basal medium containing 20 g/L rice straw or corn stalks, C. unicolor IUM 5400 produced 0.18 g and 0.18 g of ethanol per g of rice straw and corn stalks, respectively. The results suggest that C. unicolor IUM 5400 is a white rot fungus that can effectively hydrolyze cellulose or hemicellulose to sugars and simultaneously convert them to ethanol.

Following the previous study, the toxicity of a single subcutaneous administration of the Thyrokitty injection (I-131) and the side effects that may occur at therapeutic doses were confirmed. The Thyrokitty injection (I-131) was administered subcutaneously once at a dose of 0, 2.0, 6.0, and 18.0 mCi/kg, 5 male and female rats per group, and mortality, general symptom observation, and weight measurement were performed for 2 weeks, followed by observation of autopsy findings. There were no deaths, and no statistically significant weight change was observed. Mild hair loss, fissures, and crusting were observed by general symptom observation, but it was not a toxic change related to the Thyrokitty injection (I-131). Gastric atrophy and a decrease in the size of the spleen were observed by the autopsy. As a results of single subcutaneous administration of the Thyrokitty Injection (I-131) to rats at a maximum dose of 18.0 mCi/kg, a decrease in the size of the spleen and gastric atrophy were observed as the dose of the Thyrokitty Injection (I-131) increased, which may be related to the test substance. No abnormal findings related to the Thyrokitty injection (I-131) were observed. Therefore, the approximate lethal dose of the Thyrokitty injection (I-131) was 18.0 mCi/kg or more. In addition, as reported for the treatment of feline hyperthyroidism with radioiodine (131I), side effects of the Thyrokitty injection (I-131) are expected to be extremely rare. Temporary dysphagia and fever may occur, but it will recover naturally. It should be administered with caution in cats with diseases such as urinary system, cardiovascular system, gastrointestinal system and endocrine system, especially with kidney disease. And it should not be used in cats who are pregnant, lactating, or likely. It is expected that the Thyrokitty injection (I-131) can be used for clinical treatment in Korea as a veterinary drug.

Radioiodine (131I) has been used for the treatment of feline hyperthyroidism since the 1990s in the USA and Europe, and it is recommended as the most effective treatment for feline hyperthyroidism because it has a high therapeutic effect, small side effects, and does not require anesthesia. In this study, the pharmacological properties of the Thyrokitty injection (I-131), which is being developed as a treatment for feline hyperthyroidism, using radioiodine (131I) as an active ingredient, was tested. The %cell uptake of the Thyrokitty injection (I-131) in FRTL- 5 thyroid cells was 0.410 ± 0.016%, which was about 18 times higher compared to Clone 9 hepatocytes, and it was decreased by 30.7% due to the competitive reaction with iodine (sodium iodide). In addition, the %cell growth of the FRTL-5 thyroid cells was reduced by 25.0% by treatment with the Thyrokitty injection (I-131). As a result of the tissue distribution test, the Thyrokitty injection (I-131) was distributed at the highest concentration at 0.083 hours (5 minutes) after subcutaneous administration to animals in most organs except the stomach, small intestine, large intestine, muscle and thyroid gland, and it was excreted mainly through the kidneys. The stomach and thyroid gland showed a typical distribution pattern observed when radioiodine (131I) was administered. In addition, about 78.45% of the total amount of excretion was excreted within 48 hours, of which more than 85% was excreted in urine. In conclusion, the Thyrokitty injection (I-131) has the same mechanism of action, potency, absorption, distribution, metabolism and excretion characteristics as radioiodine (131I) reported in connection with the treatment of feline hyperthyroidism. In the future, using the results of this study, it is expected that the Thyrokitty (I-131) could be safely used in the clinical treatment of feline hyperthyroidism.

본 연구에서는 국내에서 재배되는 스탠다드 절화 장미의 품질 경쟁력을 갖추기 위해 국내에서 재배되어 유통되는 품종과 수입되고 있는 대표적인 품종을 대상으로 외∙내적 품질 비교 분석을 실시하였다. 외적 품질 분석 결과, 국내에서 주로 재배 되는 적색 장미 ‘Fuego’ 은 국내로 수입되고 있는 콜롬비아산 ‘Freedom’, 에티오피아산 ‘Upper class’ 과 비교 시 노화 시점까지 개화가 지속되어 화폭이 증가하고 꽃이 만개하였으며, 노화 발생이 적어 절화수명이 3일 이상 연장되었다. 분홍색 장미 또한 ‘Hera’와 콜롬비아산 ‘Mandela’, 에티오피아산 ‘Visu’ 와 비교 시 수명이 다소 연장되었으며, ‘Fuego’, ‘Hera’ 모두 향기가 다소 진하였다. 내적 품질 분석 결과, 절화수명과 유사 하였으나, 적색과 분홍색 장미 모두 에티오피아산 품종의 수분 흡수량이 다소 높았다. 그러나, 박테리아 발생량은 유의차 가 없었으며 ‘Fuego’는 꽃의 당 함량이 다소 높았다. 또한, 개화단계, 엽록소 함량, 꽃과 잎의 당 함량과 절화수명은 양의 상관관계를 보였다. 따라서, 적색 장미 ‘Fuego’는 수입산 절화 와 비교 시 품질 경쟁력을 갖출 수 있을 것으로 보이나, 수분 흡수를 원활히 하기 위해서는 농가에서 채화하는 직후부터 소비자 판매단계까지의 단계적정 보존용액 처리가 필요할 것으로 판단된다.

한약재로 사용되는 더덕과 도라지에 표고의 유용성분을 함유한 소재를 개발하고자 더덕표고균사발효물(FCLM)과 더덕도라지균사발효물(FPLM)을 제조하였다. 두 가지 발효물의 일반성분, 유리당, 유기산, β-glucan, ergothioneine, ergosterol, vitamin D2 함량 및 3T3-L1 지방전구세포의 분화에 미치는 영향을 연구하였다. 일반성분 분석결과, FCLM에서 조섬유와 조지방함량이 FPLM에 비하여 높게 나타났으며, FPLM은 조단백질과 가용성무질소물의 함량 이 FCLM에 비하여 높게 나타났다. 유리당은 FCLM과 FPLM 모두 arabinose, glucose, sucrose 3종이 검출되었으며, 총 유리당 함량은 FPLM에서 높게 나타났다. 유기 산 함량은 발효 전 더덕과 도라지에 비하여 발효 후 FCLM과 FPLM에서 낮게 나타났다. β-Glucan 함량은 FCLM과 FPLM 두 발효물에서 대조구로 사용한 표고보다 높은 함량을 보였다. 항산화 물질로 알려진 ergothioneine의 함량은 FCLM이 FPLM보다 높게 나타났다. Ergosterol 함량은 대조구로 사용한 표고에서 가장 높게 나타났으며, 발효물들은 비슷한 함량을 나타내었다. Vitamin D2는 발효물들에서만 검출되었으며, FPLM (0.58±0.01 mg%)가 FCLM (0.47±0.01 mg%)보다 높은 함량을 보였다. 더덕과 도라지 표고균사발효물인 FCLM과 FPLM는 3T3-L1 지방전구세포에 대하여 발효 전 더덕과 도라지에 비하여 높은 수준의 세포 생존율을 나타내었다. 또한 FCLM과 FPLM은 3T3-L1 지방전구세포 분화를 발효 전 더덕과 도라지에 비하여 높은 수준으로 억제하여, 비만 억제 효과 가 있는 것으로 기대된다.