Pregnancy-associated plasma protein-A (PAPP-A) is known as an important biomarker for fetal abnormality during first trimester and has a pivotal role in follicle development and corpus luteum formation. And also, it is being revealed that an expression of PAPP-A in various cells and tissues such as cancer and lesion area. PAPP-A is the major IGF binding protein-4 (IGFBP-4) protease. Cleavage of IGFBP-4 results in loss of binding affinity for IGF, causing increased IGF bioavailability for proliferation, survival, and migration. Additionally, PAPP-A can be used as a promising therapeutic target for healthy longevity. Despite growing interest, almost nothing is known about how PAPP-A expression is regulated in any tissue. This review will focus on what is currently known about the zinc metalloproteinase, PAPP-A, and its role in cells and tissues. PAPP-A is expressed in proliferating cells such as fetus in uterus, granulosa cells in follicle, dermis in wound, cancer cells, and Sertoli cells in testis. They have common characteristics of proliferation faster than normal cells with stimulating IGFs action and inhibiting IGFBPs. The PAPP-A functions and expression studies in livestock have not yet been conducted much. Further studies are needed to use PAPP-A as a marker for healthy longevity in animal science.

To clarify the concepts of dialects, vernacular and regional languages used with similar meanings, this study attempted to reveal the usage patterns and concepts of these expressions based on written corpus. The written corpus of printed newspaper articles from the online Naver News Library that archived newspaper articles from 1920 to 1999 and the news article corpus crawled by the online Naver News portal from January 1, 2004 to December 31, 2021 were extracted and analyzed. In particular, this paper analyzed the relationship between collates and keywords based on the corpus linguistic research methodology of the news article corpus for the past eighteen years and how they were being used in official records and press documents by corresponding with the 'dialects, vernacular, and regional languages' in socio-linguistic terms of modern Korean. The results are summarized as follows. First, the concept of linguistic norms that a dialects have terms corresponding to the words or standard languages was established after the 1930s. Second, in the library of newspaper articles published in the 20th century, dialects or vernaculars were perceived as negative objects to be removed in preparation for standard language. Third, it can be seen that the positive value judgment on 'vernacular' has increased in the corpus of news articles over the past decade. Fourth, dialects and vernacular, regional language, and standard language were used to be compatible with each other, and it can been seen that dialects were mainly used in academic contexts and vernacular were mainly used in everyday contexts. Fifth, it can be confirmed that the positive perception of standard language has been maintained in the 20th-century newspaper article corpus and the 21st-century news article corpus for the last eighteen years after the recognition of standard language.

해양사고 예방을 위해서는 사고의 원인과 결과에 대한 분석 및 진단뿐만 아니라, 사고의 발생 패턴과 변화 추이를 예측함으로 써 정량적 위험도를 제시할 필요성이 있다. 선박교통과 관련된 해양사고 예측은 선박의 충돌위험도 분석 및 항해 경로 탐색 등 선박교통 의 흐름에 관한 연구가 주로 수행되었으며, 해양사고의 발생 패턴에 대한 분석은 전통적인 통계 분석에 따라 제시되었다. 본 연구에서는 해양사고 통계 자료 중 선박교통관련 사고의 월별, 시간대별 발생 현황 데이터를 활용하여 해양사고 발생 예측 모델을 제시하고자 한다. 국내 해양사고 발생 현황 중 월별, 시간대별 데이터 집계가 가능한 1998년부터 2021년까지의 통계자료 중 선박교통 관련 데이터를 분류하 여 정형 시계열 데이터로 변환하였으며, 대표적인 인공지능 모델인 순환 신경망 기반 장단기 기억 신경망을 통하여 예측 모델을 구축하 였다. 검증데이터를 통하여 모델의 성능을 검증한 결과 RMSE는 초기 신경망 모델에서 월별 52.5471, 시간대별 126.5893으로 나타났으며, 관측값으로 신경망 모델을 업데이트한 결과 RMSE는 월별 31.3680, 시간대별 36.3967로 개선되었다. 본 연구에서 제안한 신경망 모델을 기 반으로 다양한 해양사고의 특징 데이터를 학습하여 해양사고 발생 패턴을 예측할 수 있을 것이다. 향후 해양사고 발생 위험의 정량적 제 시와 지역기반의 위험지도 개발 등에 관한 추가 연구가 필요하다.

장관은 대통령의 국정 운영 파트너이자, 주요 행정부처의 수장이다. 이 에 본 연구는 민주화 이후 역대 장관의 충원 패턴에 대해 살펴보고, 덧 붙여 정부 운영의 안정성을 위해 장관의 재임 기간에 영향을 미치는 요 인을 전문성 요인과 대통령-장관 연계 요인에 주목하여 경험적으로 분석 하였다. 민주화 이후 장관직을 역임한 총 489명을 대상으로 데이터를 구 축하였고, 분석결과는 다음과 같다. 첫째, 충원 패턴을 살펴본 결과 개인 적 특성 요인에 있어서는 남성이 다수였고, 평균 연령은 약 58세였으며, 학력은 높은 수준이었다. 둘째, 전문성 요인에 있어서 장관들은 대체로 전공 및 경력 등에 있어서 소속 부처와 일치된 전문성을 보유하고 있었 다. 셋째, 대통령-장관 연계 요인과 관련하여 정실주의적 요인으로는 출 신 학교보다는 출신 지역에 있어서 대통령과의 연관성이 다소 나타났으 며, 엽관주의 요인으로 동일 정당 활동 여부가 장관 인선에 영향을 미쳤 을 가능성이 존재한다는 것을 확인하였다. 넷째, 장관의 평균 재임 기간 은 약 1년 3개월로 다른 국가에 비해 짧은 수준이었다. 마지막으로, 장 관의 재임 기간에 영향을 미치는 요인을 회귀분석한 결과, 장관의 전문 성 요인의 영향력이 가장 크게 나타났다.

목적 : 본 연구의 목적은 국내 청소년의 여가참여 빈도에 따른 활동 참여 경향을 잠재프로파일 분석 (LPA)을 통해 잠재계층을 유형화 하고 그 특성을 살펴보고자 하였다. 또한 청소년의 여가참여 빈도에 따른 활동 유형의 각 잠재계층에 따라 청소년의 주관적 복지감과 행복감이 어떠한 차이를 보이는지 파 악하여 청소년의 삶의 질 증진을 위한 기초자료를 마련하기 위해 수행 되었다. 연구방법 : 국내 청소년의 여가참여 빈도에 따른 참여 유형을 파악하기 위해 한국청소년정책연구원에서 제 공한 한국아동ㆍ청소년패널조사, 청소년활동 참여실태조사 9차년도(2018년) 데이터를 활용하여 국내 청 소년 9,041명의 자료를 분석 하였다. 본 자료를 활용하여 잠재프로파일분석(LPA)을 실시하였고, 도출된 각 유형별 특성을 파악하기 위해 χ2 분석, 분산분석을 실시하였으며, 유의한 차이가 있는 경우 집단 간 차이를 알아보기 위해 Scheffe 사후검증을 실시하였다. 결과 : 청소년의 여가참여 빈도에 따른 참여 유형의 잠재프로파일을 분석한 결과 최적의 잠재계층의 수는 5개로 확인 되었다. 분류된 잠재계층을 ‘소극적 참여형’, ‘사회친목지향형’, ‘정적여가지향형’, ‘미술음악 지향형’과 ‘적극적 참여형’로 명명하였다. 또한 여가참여 빈도에 따른 참여 유형의 행복감 및 주관적 행 복감의 차이를 분석 한 결과 잠재계층별 주관적 복지감과 행복감에 통계적으로 유의미한 차이를 보였다. 결론 : 본 연구는 잠재프로파일분석을 통해 청소년의 여가활동참여 유형을 분석 하였고, 이러한 여가활동 의 참여 경향에 따라 각 개인의 주관적 복지감과 행복감에서 통계적으로 유의미한 차이가 나타남을 밝 혔다. 따라서 본 연구를 통해 청소년의 정서적 건강 증진과 삶의 만족도를 위해서 향후 청소년의 여가활 동참여와 관련된 중재프로그램 및 서비스를 제안하고자 할 때 기초자료로 활용되기를 기대한다.

The collapse of reinforced concrete (RC) frame buildings is mainly caused by the failure of columns. To prevent brittle failure of RC column, numerous studies have been conducted on the seismic performance of strengthened RC columns. Concrete jacketing method, which is one of the retrofitting method of RC members, can enhance strength and stiffness of original RC column with enlarged section and provide uniformly distributed lateral load capacity throughout the structure. The experimental studies have been conducted by many researchers to analyze seismic performance of seismic strengthened RC column. However, structures which have plan and vertical irregularities shows torsional behavior, and therefore it causes large deformation on RC column when subjected to seismic load. Thus, test results from concentric cyclic loading can be overestimated comparing to eccentric cyclic test results, In this paper, two kinds of eccentric loading pattern was suggested to analyze structural performance of RC columns, which are strengthened by concrete jacketing method with new details in jacketed section. Based on the results, it is concluded that specimens strengthened with new concrete jacketing method increased 830% of maximum load, 150% of maximum displacement and changed the failure modes of non-strengthened RC columns.

For clothing items that combine the top with the bottom, such as a jumper suit, it is necessary to design original forms to develop clothes in various styles that can satisfy aesthetic and functional needs. Therefore, to determine the original forms of women’s jumper suits, this study aimed to analyze the patterns of women’s jumper suits being sold in the market comparatively and evaluate their fitness. For the study method, this researcher obtained five types of women’s jumper suits from local brands and compared the patterns’ measured sizes, then conducted exterior evaluation on the surplus according to five different movements and analyzed the values of distortion of clothing pressure comparatively. According to the results, in the basic posture, brands A and C received favorable results, while in the other movements, brand B, which had the biggest surplus on the bottom, was evaluated favorably. In conclusion, in the patterns of women’s jumper suits, a bigger surplus is added to either the crotch length or crotch girth rather than the top length, and the top and the bottom tend to have a different surplus according to the design. In addition, based on the values of body surface lengths according to the range of movements, this study suggests that an additional surplus be added to the length.

This study was carried out the estimation on consumption patterns and consciousness of domestic forage for improvement of the quality of domestic forage. Although the cultivated area in South Korea of forage has increased significantly compared to the past, the self-sufficiency rate of domestic forage has increased to around 80% since 2010. Also, livestock farmers prefer to use import forage than domestic due to convenience of use. In Korean beef farms, the ratio of import to domestic forage was higher in domestic forage (import forage 3 : domestic forage 7). In the method of securing domestic forage, purchase of forage (55.6%) was higher than self-cultivation of forage (44.4%). The ratio of use by bailing type was shown in the order of rice staw rice straw (50.5%), domestic hay (15%), imported hay (12.5%), and total mixed ratio (10.7%). The preference of forage was in the order of amount of foreign matter, moisture content, price, feed value in Korean native cattle farm. The result of satisfaction with domestic and import forage showed that the satisfaction of domestic forage price was higher than import forage, while the moisture content and foreign matter of forage were lower than import forage. In addition, in the results of the satisfaction and importance of domestic roughage compared to imported roughage, satisfaction with imported roughage was generally high in all items except for price. As a result, in order to improve the satisfaction of domestic forage in Korean native cattle farm, it is necessary to minimize foreign matter in forage and increase hay production for moisture content uniform in forage.

곤충은 주변환경에 적응하며 발육과 번식을 통해 진화하여 왔다. 온도발육모형을 이용하여 곤충과 응애 분류군별 공통고유최적온도, 발육 최적온도, 산란최적온도를 산출하기 위해 112편의 논문에서 응애류 14종, 딱정벌레목 8종, 파리목 5종, 노린재목 31종, 벌목 7종, 나비목 18종, 메뚜기목 1목, 다듬이벌레목 5종, 총채벌레목 5종의 온도발육과 산란자료를 분석하였다. 분석을 통하여 총채벌레목을 제외하고 공통고유최적온 도는 발육최적온도보다는 산란최적온도와 차이가 적었다. 본 종설을 통해 공통고유최적온도는 발육최적온도보다는 산란최적온도와 밀접한 관계 가 있을 가능성이 높음을 제안하였다.

The time series data of rotifer community focusing on the species number and total density were collected from 29 reservoirs located at Jeonnam Province from 2008 to 2016 quarterly. The reservoirs had similar weather condition during the study period, but their sizes and water qualities were different. To analyze the temporal dynamics of rotifer community, the medians, ranges, outliers and coefficient of variation (CV) value of rotifer species number and abundance were compared. For the temporal trend analysis, time series of each reservoir data were compared and clustered using the dynamic time warping function of the R package “dtwclust”. Small-sized reservoirs showed higher variability in rotifer abundance with more frequent outliers than large-sized reservoirs. On the other hand, apparent pattern was not observed for the rotifer species number. For the temporal pattern of rotifer density, COD, phytoplankton abundance fluctuation, and cladoceran abundance fluctuation have been suggested as potential factor affecting the rotifer abundance dynamics.

The aim of this study was to develop a body type suitable for adult men aged from their 20s to their 40s and to present a method of drafting related patterns. To this end, the somatic surface pattern data from previous studies were used. The research method involved drafting torso patterns for each type by setting and distributing the ease to the somatic surface pattern. Appearance evaluation was performed with virtual clothing. Then, the torso pattern for each body type was completed and presented as a draft method. SPSS was used for data analysis in this study. The research results are as follows. Types 1, 2, and 3 were set to 7%, 6%, 5%; 7%, 6%, 4%; and 6.5%, 7%, and 6% for chest, waist, and hip circumference measurements, respectively. The ratio of front to back was 50%:50%, 50%:50%, and 50%:50% of the spare for each body part for Type 1; 70%:30%, 50%:50%, and 60%:40% for Type 2, and 60%:40%, 70%:30%, and 60%:40% for Type 3. A tight-fit torso pattern for each body type suitable for adult males in their 20s to 40s was drafted, which was modified and supplemented through the evaluation of the first and second virtual wear. Considering the practicality of this approach, for generalization of the patterns, the items of the pattern were converted into a drafting method and presented as a draft method.

Depression is one of the most important psychiatric disorders worldwide. Most depression-related data mining and machine learning studies have been conducted to predict the presence of depression or to derive individual risk factors. However, since depression is caused by a combination of various factors, it is necessary to identify the complex relationship between the factors in order to establish effective anti-depression and management measures. In this study, we propose a methodology for identifying and interpreting patterns of depression expressions using the method of deriving random forest rules, where the random forest rule consists of the condition for the manifestation of the depressive pattern and the prediction result of depression when the condition is met. The analysis was carried out by subdividing into 4 groups in consideration of the different depressive patterns according to gender and age. Depression rules derived by the proposed methodology were validated by comparing them with the results of previous studies. Also, through the AUC comparison test, the depression diagnosis performance of the derived rules was evaluated, and it was not different from the performance of the existing PHQ-9 summing method. The significance of this study can be found in that it enabled the interpretation of the complex relationship between depressive factors beyond the existing studies that focused on prediction and deduction of major factors.

본 연구는 염화나트륨에 의한 비생물적 스트레스가 생육과정 중의 느타리에게 미치는 영향을 자실체의 생육특성, 그리고 구성아미노산함량과 향기패턴 분석을 통해 확인하였다. 농도별로 염화나트륨을 처리한 톱밥배지에서 수확한 느타리 자실체의 생육특성을 조사한 결과, 처리구별 수량은 무처리구 대비 염화나트륨 0.5%처리구에서의 값은 비슷 했으며, 염화나트륨 처리 농도가 1.0%에서 2.0%으로 증가하면서 수량이 확연히 감소하였다. 자실체의 구성아미노산함량 분석결과, 무처리구 대비 모든 염화나트륨 처리구에서 glutamic acid과 proline을 제외한 aspartate, threonine, serine, glycine, alanine, methionine, valine, isoleucine, leucine, phenylalanine, tyrosine, lysine, histidine, arginine의 14종 구성아미노산의 함량이 낮음을 확인하였다. 자실체의 향기패턴 분석결과, 염화나트륨 처리구에서 버섯고유의 향을 나타내는 octane compound로 추정되는 물질의 intensity가 감소하였음을 chromatography상에서 확인하였다.