비임상시험관리기준에서 독성시험 전 분석법 밸리데이션은 농도 설정 및 시료 제조 측면에서 중요하다. 시험기관에서는 의뢰받은 시험물질 2종에 대한 밸리데이션을 고성능액체크로마토그래피를 이용 하여 수행한 결과 특이성, 시스템 적합성, 직선성, 일내 재현성, 균질성, 안정성, 농도분석, 품질관리를 판정 기준에 만족하는 분석방법을 확립 및 검증하였다. 하지만 의뢰기관의 시험성적서상 표준물질 함량은 시험 기관의 결과보다 1.34배, 1.17배 높은 결과로 나타나 비임상시험관리기준에 적합한 분석법 밸리데이션을 통한 결과 도출이 신뢰성과 안정성 확보 측면에서 중요함을 확인하였다.
A software simulator is developed for verifying the VLBI Correlation Subsystem (VCS) trial product hardware. This software simulator includes the delay tracking, fringe rotation, bit-jump, FFT analysis, re-quantization, and auto/cross-correlation functions so as to confirm the function of the VCS trial product hardware. To verify the effectiveness of the developed software simulator, we carried out experiments using the simulation data which is a mixed signal with white noise and tone signal generated by software. We confirmed that the performance of this software simulator is similar as that of the hardware system. In case of spectral analysis and re-quantization experiment, a serious problem of the VCS hardware, which is not enough for expressing the data stream of FFT results specified in VCS hardware specification, was found by this software simulator. Through the experiments, the performance of software simulator was verified to be efficient. In future, we will improve and modify the function of software simulator to be used as a software correlator of Korea-Japan Joint VLBI Correlator (KJJVC).
Recently, the use of eco-friendly deicer is recommended for solving problem of chloride deicing salts. The laboratory tests are often used to evaluate deicer performance, but they have been shown to correlate poorly to actual field performance. Thus, we would like to introduce the field test method for improving the performance qualification of anti-icing materials.
Field test was carried out to verify the performance of high-performance Weigh-In-Motion system which was developed to enhance the precision and durability. As a result, the overall measurement error has been distributed in the range of 5 % for total weight and axle weight of vehicle.