Reuse of industrial effluents through the cooling systems in a petrochemical complex was described. The partial oxidation of the effluents from the biological treatment plant was examined, using Fenton`s reagent as a pretreatment step prior to a next treatment of the effluents. Next tertiary treatment using fixed-film reactor resulted in marked reductions in COD and suspended solids. The continuous fixed-film process with Fenton oxidation pretreatment showed a 23% increase in the COD removal efficiency when compared to that without pretreatment of Fenton oxidation under the volumetric organic loading rate of 0.1 ㎏ COD/㎥/day. The Fenton oxidation treatment seemed to be a possible method for tertiary biological treatment to reduce the residual toxicity with the enhanced biodegradation of the effluents.