본 연구는 남한 지역에서 서식하는 멸종 위기 종 2급인 왕은점표범나비의 기후 변화에 따른 서식지 변화를 분석하고자 한다. 이를 위해 단일모델의 장단점을 보완하기 위해서 생물 보전과 동물 생태학 분야에서 널리 사용 되는 앙상블 모델을 활용하여 기후변화 시나리오 자료를 이용하여 현재와 미래 기후 조건에서의 잠재적 서식지 변화를 평가하였다. 연구 결과에 따르면, 미래에는 왕은점표범나비의 서식지가 줄어들 것으로 예상되며, 이 변화 는 기온과 강수량 모두에 영향을 받을 것으로 나타났다. 특히 강수량의 계절적 변동이 가장 큰 영향을 미칠 것으로 분석되었다. 이러한 결과는 기후 변화로 인한 생물종의 서식 분포의 이해를 향상시켜 멸종 위기 종 관리와 생태계 복원과 같은 다양한 분야에서 생물다양성 증진을 위한 중요한 기초 데이터로 활용될 것으로 기대된다.

Biological control in agriculture is an eco-friendly pest management method. Numerous parasitoid wasps have been utilized as natural enemies and biological control agents. However, due to a shortage of fundamental taxonomic information caused by taxonomic impediments, there are challenges in unveiling and developing hymenopteran biological control agents. Braconidae, the second-largest family in Hymenoptera, comprises approximately 25,000 species described and recorded. All known braconids attack only insect hosts, with many members exhibiting high host specificity. Leveraging their unique biology, many braconid species have been tested in biological control research, and some have been developed as commercial products. To create a synergistic effect between biological control and taxonomic research and to discover effective biological control agents, several collaborative research projects have been conducted. In this presentation, these collaborative research projects will highlight the critical role of bridging taxonomic knowledge and biological control expertise, offering potential solutions for more effective and sustainable pest management practices in agriculture.

Background: A decrease in physical activity has been observed due to the global pandemic, resulting in the onset and progression of musculoskeletal disorders as chronic diseases. Objectives: This study aimed to assess the difference in the degree of contraction of the lower limb muscles between the existing vertical vibration method and a new cross-vibration method. Design: Randomized controlled trial. Methods: The exercise program using whole-body vibration equipment was conducted for 12 sessions, 25 min per session, three times per week for 4 weeks. Results: The changes over time showed a significant difference in cross-alternating vibrations (P<.05), except for the lateral gastrocnemius and tibialis anterior, with no significant difference in sonic vertical vibration (P>.05). The interaction between time and group was significant for all muscles (P<.05), except for the biceps femoris, with differences between before the program and at 2 and 4 weeks after the program revealed in the post-hoc analysis. Conclusion: Future studies should further evaluate the use of CAV exercise devices as auxiliary equipment in exercise by assessing different groups and variations in intensity.

This study investigates how native Korean speakers, who moved from Kyungsang province to Seoul, acquire /w/ retainment in Seoul Korean (SK). The specific objective is to examine how mobile speakers adopt the SK-like /w/ retainment and evaluate how linguistic and non-linguistic factors influence this acquisition. Furthermore, the study aims to establish whether having explicit awareness of the SK-like /w/ retainment is a prerequisite for acquiring it. The overall results suggest that most speakers have successfully adopted the SK-like /w/ retention, but there is noticeable diversity among speakers in terms of the extent to which they retain /w/. This variability can be linked to linguistic and non-linguistic factors, such as where /w/ appears in speech and individual attitudes towards SK. This research sheds light on the acquisition of /w/ retainment among native Korean speakers who have relocated from Kyungsang province to Seoul, highlighting the impact of linguistic and non-linguistic factors. It underscores the role of explicit awareness and reveals significant interspeaker variation in the adoption of SK-like /w/ retainment, contributing to our understanding of dialect acquisition dynamics.

Degenerative arthritis is a common joint disease that affects many elderly people and is typically diagnosed through radiography. However, the need for remote diagnosis is increasing because knee pain and walking disorders caused by degenerative arthritis make face-to-face treatment difficult. This study collects three-dimensional joint coordinates in real time using Azure Kinect DK and calculates 6 gait features through visualization and one-way ANOVA verification. The random forest classifier, trained with these characteristics, classified degenerative arthritis with an accuracy of 97.52%, and the model's basis for classification was identified through classification algorithm by features. Overall, this study not only compensated for the shortcomings of existing diagnostic methods, but also constructed a high-accuracy prediction model using statistically verified gait features and provided detailed prediction results.

Tulsi (Ocimum sanctum), commonly known as Holy Basil is a revered herb with a rich history in traditional medicine systems, particularly in Southeast Asia. For its medicinal properties, Tulsi has been regarded as an “Elixir of Life” and has been used to treat various ailments. However, the comprehensive investigation of Tulsi extracts and their potential pharmacological benefits, specifically in relation to antioxidant activity remains limited. Hence, the objective of this study was to evaluate the antioxidant activity of Tulsi leaf and stem extract using various screening methods. We investigate the antioxidant activity exhibited by the extract using three different methods involved the utilization of the total polyphenol content assay, the ferric reducing power assay and 2, 2-diphenyl-1-14 picrylhydrazyl (DPPH) assays. The results revealed that the Tulsi leaf extract (TLE) exhibited significantly higher antioxidant activity when compared to the Tulsi stem extract (TSE) in all the performed assays. The higher content of phenolics in TLE may have contributed to its superior antioxidant activity. The HPLC (high performance liquid chromatography) analysis of TLE revealed the presence of eugenol, active compound for several therapeutic properties. These findings provide an understanding of the bioactive compounds present in Tulsi extracts and their potential antioxidant benefits.

Background: Efficient gene editing technology is needed for successful knock-in. Homologous recombination (HR) is a major double-strand break repair pathway that can be utilized for accurately inserting foreign genes into the genome. HR occurs during the S/G2 phase, and the DNA mismatch repair (MMR) pathway is inextricably linked to HR to maintain HR fidelity. This study was conducted to investigate the effect of inhibiting MMR-related genes using CdCl2, an MMR-related gene inhibitor, on HR efficiency in HC11 cells. Methods: The mRNA and protein expression levels of MMR-related genes (Msh2, Msh3, Msh6, Mlh1, Pms2), the HR-related gene Rad51, and the NHEJ-related gene DNA Ligase IV were assessed in HC11 cells treated with 10 μM of CdCl2 for 48 hours. In addition, HC11 cells were transfected with a CRISPR/sgRNA expression vector and a knock-in vector targeting Exon3 of the mouse-beta casein locus, and treated with 10 μM cadmium for 48 hours. The knock-in efficiency was monitored through PCR. Results: The treatment of HC11 cells with a high-dose of CdCl2 decreased the mRNA expression of the HR-related gene Rad51 in HC11 cells. In addition, the inhibition of MMR-related genes through CdCl2 treatment did not lead to an increase in knock-in efficiency. Conclusions: The inhibition of MMR-related gene expression through high-dose CdCl2 treatment reduces the expression of the HR-related gene Rad51, which is active during recombination. Therefore, it was determined that CdCl2 is an inappropriate compound for improving HR efficiency.

간 동적 조영검사에 사용하고 있는 VIBE 시퀀스의 고식적인 방법과 딥러닝 방법에 관한 선행된 연구가 부족하여 영상의 평가와 검사의 방향성 및 타당성을 제시하고자 한다. ACR 팬텀 실험은 30회 반복 실험하였고, 저 대조도 분해능 평가영역 에서 syngo.via View&Go를 이용하여 신호대잡음비와 대조대잡음비를 평가하였고, 공간분해능 평가영역에서 MATLAB 을 통해 신호강도의 높이와 반치폭으로 공간 분해능을 평가했다. 팬텀 실험을 기준으로 Matrix 352를 설정하여 30명의 환자 실험을 했다. 간 실질, 간 문맥, 내림 대동맥에서 대조대잡음비를 평가했고, 공간 분해능은 간 문맥, 내림 대동맥의 경계면을 평가했다. 결과 분석은 이원배치 분산 분석으로 진행하고, 사후 분석은 Duncan을 사용했다. 통계분석은 정량적 으로 p-value 0.05 미만으로 유의한 것으로 판단했다. 팬텀 실험의 신호대잡음비와 대조대잡음비 결과는 Matrix 416 이하에서 유의하였으며, 공간분해능 결과는 고식적인 방법 Matrix 352 이하, 딥러닝 방법 288 이하에서 평가할 수 없었 다. 환자 실험 결과는 신호대잡음비, 대조대잡음비, 공간분해능 모두 유의했다. 본 연구는 고식적인 방법보다 딥러닝 방법 이 영상은 더 향상되었고, 획득 시간은 평균 4초(22.4%)가 단축되었다. 딥러닝 방법에서 Matrix 352를 적용하였을 때 검사 시간의 감소로 재현성과 호흡에 의한 인공물 감소가 있었다. 이에 딥러닝 방법에서 Matrix size 적용의 방향성을 제시할 수 있었다.

This study investigated the conditions under which consumer participatory corporate social responsibility (CSR) campaigns could be effective and focused on power as the key variable. Specifically, based on motivational intensity theory, the interaction effect between participation effort and power was examined on CSR attitude and participation intention. In addition, this study tested the mediated moderating effect of power through self-efficacy in order to examine the mechanism behind the interaction effect. Results of two experimental studies (Study 1 and Study 2) showed a significant the interaction effect of participation effort and power on participation intention. When the consumer's power was low, participation intention was lower for those in the high effort condition compared to those in the low effort condition. On the other hand, when power was high, there was no difference in participation intention according to the level of participation effort. This study has significance in that it reaffirms and furthermore expands the existing academic results and presents practical implications.

목적 : 본 연구에서는 다양한 방법의 시각적 수행을 실시하는 시기능 훈련에 있어서 원, 근거리 외사위를 가진 남녀의 시기능훈련 전, 후 성별 차이에 따른 주시시차에 미치는 영향에 대하여 알아보고자 하였다. 방법 : 대상자는 20대의 성인 남녀 총 30 명으로 교정시력은 양안 1.0 이상이며 사시자는 실험에서 제외되었 다. 시기능훈련 전, 후 양안시기능 검사와 주시시차 검사를 실시하였고 그 중 외사위를 가진 대상자의 시기능훈련 전, 후 외사위량 감소와 주시시차의 향상도를 남녀 성별에 따라 비교 분석하였다. 결과 : 원거리 시기능훈련 전, 후 남녀(남자: 11명, 여자: 16명)에 따른 외사위 감소량은 남자일 때 시기능훈련 후 외사위량이 1.50±0.79Δ으로 유의하게 감소하였고(p=0.046), 여자일 때 시기능훈련 후 외사위량이 1.56±0.50Δ 으로 유의하게 감소하였다(p=0.005). 반면, 주시시차에서 남자는 6.70±2.29로 유의한 감소를 보였으나(p=0.042), 여자의 경우 3.49±0.89로 유의한 감소는 없었다(p=0.655). 근거리 시기능훈련 전, 후 남녀(남자: 14명, 여자: 14명) 에 따른 외사위 감소량은 남자일 때 시기능훈련 후 외사위량이 5.50±1.56Δ으로 유의하게 감소하였고(p=0.036), 여자일 때 시기능훈련 후 외사위량이 4.28±0.88Δ으로 유의하게 감소하였다(p=0.004). 반면, 주시시차 검사에서 남자는 4.96±1.03으로 유의한 감소를 보였으나(p=0.031), 여자의 경우 3.37±0.92로 유의한 감소는 없었다 (p=0.655). 결론 : 남녀 성별에 따른 외사위의 주시시차는 시기능 훈련 후 여성보다 남성에서 주시시차가 감소되었음을 유 의미하게 확인할 수 있었다.

본 연구는 민간기업과는 다른 특성을 보이는 공공기관 HRD의 평가지표 도출이 필요하다는 문제의식에 서 출발하였으며, 공공기관 HRD 체계의 타당한 평가 준거 개발을 목적으로 한다. 이를 위해 CIPP 모형을 활용하여 공공부문 HRD체계와 과정 준거를 개발했던 연구사례를 분석하고, 국내 공공기관 인적자원개발 실무자 6인 대상의 심층 인터뷰를 실시하여 15개 평가영역, 41개 평가항목, 56개 평가지표로 구성된 평가 준거 초안을 도출하였다. 평가준거 초안에 대한 타당성을 확보하고자 학계, 실무, 컨설팅 전문가 12인을 대상으로 2차의 델파이 조사를 거쳐 평가 준거를 확정하였다. 최종적인 평가 준거는 요구분석, 기관장 리더 십, HRD 인력 전문성, 경영성과 등 15개 영역, 37개 항목, 45개 지표로 도출되었다. 본 연구는 공공기관의 양면적 성격을 반영한 공공기관 HRD 체계의 평가 준거를 제시했다는 데 의의가 있다. 본 연구는 다양한 공공기관의 사업 특성을 감안한 평가 준거 보완이 필요하다는 점을 제언하였다.