The occurrence of allergic disease has increased harmfully in the last few decades. Atopic dermatitis (AD) is an allergic inflammation disorder characterized by itchy, red, swollen, cracked skin. Although the pathogenesis of AD is not fully understood, it is assumed that deregulation of T-helper 1 (Th1) and T-helper 2 (Th2) immune responses, a predominance of allergen-specific IgE, and interrupted epidermal barrier function are keys to the pathogenic mechanism. Activated T helper 2 (Th2) immune function is hallmark of various allergic diseases. Oxidative stress implicated in cutaneous damage in various inflammatory skin diseases.
We investigated the effect of fermented soybean (SCGB1) on the improvement of AD. Soybean fermentation was carried out using B. amyloliquefaciense SCGB1 (KCCM11964P), which is known to produce of natural antibiotics. And then, we experiment of SCGB1 and soybean powder (NC) in DNCB-induced AD model. Mice were respectively oral administration of variety dose for 14 days. As a results, it was confirmed that serum Immunoglobulin E (IgE) expression was dose-dependently decreased in SCGB1 and NC compared to negative control, and it was reduced the skin pruritus inducing factor that Interleukin-31 (IL-31) mRNA level. In addition, the inflammatory cells were infiltration in skin for histological analysis. As a result, it reduced that epidermal hyperplasia, cancellation and aveolarization compared to negative control. These results suggest that SCGB1 may be effective for prevention and treatment of AD.
자기 주도적으로 자신에게 맞는 자료와 정보통신 기술을 활용하는 학습유도 정책인 스마트교육은 현재 한국 교육의 중요한 목표중 하나이다. 스마트교육에 적합한 과학교육을 위한 스마트 콘텐츠의 주요 고려사항은 사용자의 수준과 적성을 고려한 자기 주도적이고 흥미로운 콘텐츠를 만드는 것이다. 특히 실험을 통하여 이론을 배우는 과학교육의 특성상 사용자 스스로 실험을 할 수 있는 내용이 포함되어야 한다. 본 연구는 초중등 과학 교과 과정의 교육목표를 충족시키는 실험을 통하여 이론을 학습할 수 있는 스마트교육 콘텐츠 개발에 대한 것이다. 초, 중등 과학 교과과정 중 물리의 기본이 되는 뉴턴의 운동법칙을 연구 대상으로 선정하였다. 전통적인 과학실에서 교사 한명이 다수의 학생을 상대로 교육하는 과학 실험이 가진 시간, 장소, 경제적 제한 그리고 실험시 안전사고의 가능성과 같은 단점들을 보완하고, 모든 사용자에게 평등한 배움의 기회를 가지도록 하는 것을 목표로 하였다. 본 연구에서 개발한 정규 교과과정을 충족하는 시리어스게임 형태의 뉴턴의 운동법칙 실험 콘텐츠를 통해 스마트교육시대의 교육 현장에서, 새로운 방식의 실험 콘텐츠의 가능성을 보여줄 수 있을 것이다.
Chamaecyparis obtusa is one of the economical conifers planted in Korea due to its good quality timber and wood characteristics. Individuals of C. obtusa containing high terpenes (HT) and low terpenes (LT) were selected for by colorimetric method. The HT of C. obtusa was delayed in wilting against various abiotic stresses compared to the LT plants. The HT group exposed to UV did not significant influence the chlorophyll content, and the chlorophyll value was higher in the HT group than the LT group. Also, chilling treatment (5℃) did not significant influence on the chlorophyll content. However treatment at -4℃ showed relatively low chlorophyll content in the LT group than the HT group. Plants exposure to high temperature was not a difference between the HT and the LT group. However, treatment at 38℃ influenced the chlorophyll content that was increased exposure time-dependently. In salt treatments, chlorophyll in the HT group was lower at high concentrations (300 and 500 mM) of NaCl. However, chlorophyll content increased to slightly in treatment time-dependently, which is 6.7% to 40%. H2O2 treatment has been a negative effect on the chlorophyll content in the HT group. All concentration of H2O2 decreased the chlorophyll content of 5% to 35%. Plants containing high terpenoids were resisted against some abiotic stress such as salt and H2O2. Our results implied that terpenoids could cause various abiotic stress resistance. These results could be utilized for efficient management and biomass production during forest silvicultures.
Bamboo forests are fast-growing, renewable resources, and their carbon sequestration potential has attracted increasing attention. Although bamboo can be used for many purposes, bamboo forests in Korea represent a generally underutilized resource. The main objective here was to perform an assessment of the physical and mechanical characteristics of different species of bamboo found in Korea. The main species of domestic bamboo are Phyllostachys bambusoides, P. pubescens, and P. nigra; we measured the air-dried density for each of the species, with obtained values of 0.89 g/cm2, 0.79 g/cm2, and 0.83 g/cm2, respectively, giving the density order of P. bambusoides > P. pubescens > P. nigra, with P. bambusoides having the highest density. We then measured the compressive strength of each species, which were 802.84 kgf/cm2, 624.69 kgf/cm2, and 743.77 kgf/cm2, respectively, in the order of P. bambusoides > P. pubescens > P. nigra, with P. bambusoides having the highest compressive strength. Volume and maximum load decreased with increasing node height in the three bamboo species, whereas air-dried density and compressive strength increased. Our results thus add to the pool of essential knowledge about Korean bamboo species, and consequently to the development of a potentially valuable domestic resource in Korea.
The marine industry contributes a large proportion of the air pollutant emissions along coastal regions, and this air pollution has been strongly linked to cardiovascular diseases and other illnesses. To alleviate the problem, many ports have installed alternative maritime power (AMP) facilities that enable onboard marine auxiliary engines with generators (gensets) to be shut down while a ship is at berth. This study compared the emissions from conventional gensets with those from AMP facilities, focusing on four emission types: greenhouse gases (GHG), sulphur oxides (SOX), nitrogen oxides (NOX), and particulate matter (PM). Both direct (combustion / operation) and indirect (upstream) emissions were considered together for the emission comparison. The results showed that AMP has lower emissions than conventional onboard gensets, and this benefit is highly dependent on the electricity generation mix onshore. On average, GHG emissions could be reduced by about 18.3 %, while the other emissions (SOX, NOX, and PM) would decrease more dramatically (88.4 %, 90.1 %, and 91.5 %, respectively). Additionally, future benefits of the AMP would increase due to the expansion of renewable energies. Thus, this study supports the potential of AMP as a promising solution for environmental concerns at ports worldwide.
The photovoltaic properties of TiO2 used for the electron transport layer in perovskite solar cells(PSCs) are compared according to the particle size. The PSCs are fabricated and prepared by employing 20 nm and 30 nm TiO2 as well as a 1:1 mixture of these particles. To analyze the microstructure and pores of each TiO2 layer, a field emission scanning electron microscope and the Brunauer–Emmett–Teller(BET) method are used. The absorbance and photovoltaic characteristic of the PSC device are examined over time using ultraviolet-visible-near-infrared spectroscopy and a solar simulator. The microstructural analysis shows that the TiO2 shape and layer thicknesses are all similar, and the BET analysis results demonstrate that the size of TiO2 and in surface pore size is very small. The results of the photovoltaic characterization show that the mean absorbance is similar, in a range of about 400-800 nm. However, the device employing 30 nm TiO2 demonstrates the highest energy conversion efficiency(ECE) of 15.07 %. Furthermore, it is determined that all the ECEs decrease over time for the devices employing the respective types of TiO2. Such differences in ECE based on particle size are due to differences in fill factor, which changes because of changes in interfacial resistance during electron movement owing to differences in the TiO2 particle size, which is explained by a one-dimensional model of the electron path through various TiO2 particles.
Background: After stroke, in order to improve gait function, it is necessary to increase the muscle strength and to enhance the propriocetive function of the lower extremity.
Objects: This study aimed to compare the effects of open kinetic chain (OKC) versus closed kinetic chain (CKC) isokinetic exercise of the hemiparetic knee using the isokinetic equipment on lower extremity sensorimotor function and gait ability in patients with chronic stroke.
Methods: Thirty participants with chronic hemiplegia (> 6 months post-stroke) were randomly divided into 2 equal groups: CKC group and OKC group. Patients from both groups attended conventional physiotherapy sessions 3 times a week for 6 weeks. Additionally, subjects from the CKC group performed isokinetic exercise using the CKC attachment, while those from the OKC group performed isokinetic exercise using the OKC attachment. The isokinetic knee and ankle muscles strength, position sense of the knee joint, and spatiotemporal gait parameters were measured before and after interventions.
Results: The knee muscles peak torque/body weight (PT/BW) and hamstring/quadriceps (H/Q) ratio significantly increased in both groups (p<.01). In particular, ankle plantarflexors PT/BW, position sense of the knee, gait velocity, and spatial gait symmetry significantly improved in the CKC group (p<.01, p<.05, p<.01, and p<.01, respectively).
Conclusion: CKC isokinetic exercise can be an effective therapeutic intervention for the improvement of sensorimotor function of the lower extremity and gait functions, such as gait velocity and symmetry. CKC position in isokinetic strength training is effective to improve functional ability in patients with chronic stroke.