Persistent left cranial vena cava (PLCVC) is a remnant vessel connected with the coronary sinus and draining into the right atrium. A 3-month-old intact male Bichon Frise was evaluated for the presence of a mechanical murmur auscultation in the local animal hospital. No significant clinical signs were present on physical examination except mechanical murmur. Patent ductus arteriosus (PDA) was diagnosed in the imaging procedure. During the left thoracotomy, PLCVC was found. The vascular malformation made the surgical process difficult by hiding PDA from the left thoracotomy surgical view. PLCVC and the vagus nerve was carefully dissected and lifted to secure a clear surgical view of PDA. The ductus arteriosus was ligated. Computed tomography angiography (CTA) was performed postoperatively. On CTA, left brachiocephalic vein retaining connection with the coronary sinus draining into the right atrium was observed. CTA is highly recommended for dogs with PDA to provide better postoperative results.

This study aimed to examine the effect of a mild elevation in serum cholesterol level in a porcine coronary overstretch restenosis model using a balloon angioplasty catheter or drug-eluting coronary stent. Pigs were divided into two groups and were fed a commercial normal diet (CND, n = 4) or a high-fat diet (HFD, n = 4) for 5 weeks. Coronary overstretch injury by balloon angioplasty or stent implantation was induced in the left anterior descending and left circumflex artery after 1 week of feeding. Histopathological analysis was performed at 4 weeks after coronary injury. During the experiment, the total cholesterol level in the HFD group increased by approximately 44.9% (from 65.9 ± 3.21 mg/dL at baseline to 95.5 ± 9.94 mg/dL at 5 weeks). The lumen area in the CND group was reduced in comparison with that in the HFD group after balloon angioplasty. After stent implantation, the injury score showed no significant difference. There were significant differences in the neointimal area (2.7 ± 0.33 mm2 in the CND group vs. 3.3 ± 0.34 mm2 in the HFD group, p<0.05), lumen area (2.6 ± 0.54 mm2 in the CND group vs. 2.0 ± 0.33 mm2 in the HFD group, p<0.05), and percent area stenosis (52.0 ± 7.96% in the CND group vs. 62.4 ± 5.15% in the HFD group, p<0.05). Body weight change was not different between the two groups. Increased serum cholesterol level activated vascular smooth muscle cell proliferation in the porcine coronary overstretch model.

PURPOSES : Almost every design method for airport concrete pavements considers only traffic loading and not environmental loading. This study proposes a mechanistic design method for airport concrete pavements, that considers both environmental and traffic loading simultaneously. METHODS: First, the environmental loading of concrete pavements in Korean airports was quantified. FEAFAA, a finite element analysis program for airport pavements, was used to calculate the maximum tensile stress (MTS) of the slab, caused by both environmental and traffic loadings. The factors that influence the MTS were identified via sensitivity analysis, and an MTS prediction model was developed using the statistical analysis program SPSS. The ratio of MTS to the tensile strength of slab was calculated using the prediction model. The fatigue model under the AC 150/5320-6E and AC 150/5320-6F standards of the FAA was corrected to make it suitable for the predicted stress-strength ratio. RESULTS : The MTS prediction model and corrected fatigue model were used to redesign the slab thickness and joint spacing of airport concrete pavements originally designed using the AC 150/5320-6D standard, which empirically considers traffic loading only. As a result, different slab thicknesses and joint spacings were redesigned with consideration for environmental loading, specifically the weather conditions of airports. . CONCLUSIONS: The slab thickness and joint spacing can be mechanistically designed at the same time, whereas previously, only the slab thickness was designed, and the joint spacing was determined empirically.