목 적: 본 연구의 목적은 3D 안경 또는 스마트 글라스와 같은 대량생산형 안경테의 착용감을 평가하는데 있어 EEG 측정의 유용성을 보이는 것이었다. 방 법: 무작위 순서로 2 종류의 대량생산형 안경테(안경테-A와 -B)를 착용하고 있는 동안 40명의 피검자의 뇌파 강도를 주파수에 따라 측정하였다. 2 종류의 안경테에 대해서 측정된 α파의 시간에 대하여 평균 한 상대강도를 서로 비교하였다. 결 과: 안경테 A의 시간에 대하여 평균한 α파의 상대강도가 안경테 B의 시간에 대하여 평균한 α파의 상대강도보다 통계적으로 유의하게 더 강한 것으로 나타났다. 결 론: 시간에 대하여 평균한 α파의 상대강도는 대량생산형 안경테의 착용감을 상대적으로 비교하는데 있어 객관적인 지표로 활용될 수 있다.

This study was conducted to assess the potential of using NIRS to accurately determine the chemical composition and fermentation parameters in fresh coarse sorghum and sudangrass silage. Near Infrared Spectroscopy (NIRS) has been increasingly used as a rapid and accurate method to analyze the quality of cereals and dried animal forage. However, silage analysis by NIRS has a limitation in analyzing dried and ground samples in farm-scale applications because the fermentative products are lost during the drying process. Fresh coarse silage samples were scanned at 1 nm intervals over the wavelength range of 680~2500 nm, and the optical data were obtained as log 1/Reflectance (log 1/R). The spectral data were regressed, using partial least squares (PLS) multivariate analysis in conjunction with first and second order derivatization, with a scatter correction procedure (standard normal variate and detrend (SNV&D)) to reduce the effect of extraneous noise. The optimum calibrations were selected on the basis of minimizing the standard error of cross validation (SECV). The results of this study showed that NIRS predicted the chemical constituents with a high degree of accuracy (i.e. the correlation coefficient of cross validation (R²cv) ranged from 0.86~0.96), except for crude ash which had an R² cv of 0.68. Comparison of the mathematical treatments for raw spectra showed that the second-order derivatization procedure produced the best result for all the treatments, except for neutral detergent fiber (NDF). The best mathematical treatment for moisture, acid detergent fiber (ADF), crude protein (CP) and pH was 2,16,16 respectively while the best mathematical treatment for crude ash, lactic acid and total acid was 2,8,8 respectively. The calibrations of fermentation products produced poorer calibrations (RPD < 2.5) with acetic and butyric acid. The pH, lactic acid and total acids were predicted with considerable accuracy at R²cv 0.72~0.77. This study indicated that NIRS calibrations based on fresh coarse sorghum and sudangrass silage spectra have the capability of assessing the forage quality control

To determine the effect of diabetes on root resorption in periodontitis, we investigated odontoclast formation and root resorption in diabetic rats with periodontitis. Odontoclast formation was observed in three groups of F344 rats: Controls (C) were normal rats without diabetes or periodontitis; the periodontitis (P) group had mandibular first molars to be ligatured; the periodontitis with diabetes (PD) group was intravenously administered streptozotocin (50 mg/kg) to induce diabetes and had mandibular first molars to be ligatured. On days 3, 10, and 20 after ligature, tumor necrosis factor (TNF)-α and receptor activator of nuclear factor-κB ligand (RANKL) expression, odontoclast formation, and root resorption areas were evaluated by immunohistochemistry, tartrate-resistant acid phosphatase staining, and hematoxylin and eosin staining, respectively. The PD group showed frequent urination, weight loss, and hyperglycemia. Numbers of TNF-α- and RANKL-positive cells were higher in the P and PD groups than in the C group. It was more prevalent in PD group on day 3. Odontoclast formation was greater in the P and PD groups than in the C group on days 3 and 10, then decreased to same level as the C group by day 20. Root resorption in the PD and P groups showed increases on days 3 and 10, respectively, compared to the C group. These results suggest that diabetes may transiently increase root resorption on day 3 with high expression of TNF-α and RANKL after periodontitis induction. This study could aid the understanding of root resorption in diabetic patients with periodontitis.

Leptin is one of the adipocytokines produced from adi- pose tissue but its functions in periodontal tissue have not previously been investigated. In our current study, we exa- mined the effects of leptin on the expression of interleukin (IL)-6 and IL-8 in periodontal ligament (PDL) cells and gingival fibroblasts. Leptin receptor expression was evalua- ted by RT-PCR and the production of cytokines was mea- sured by ELISA. The phosphorylation of Akt and Erk1/2 was assessed by western blotting. mRNA of long and short form leptin receptors were detected in both PDL cells and gingival fibroblasts. Leptin was found to increase the pro- duction of IL-6 and IL-8 in both of these cell types, an effect which was not blocked by polymyxin B, an inhibitor of lipopolysaccharide (LPS). Leptin did not alter the pro- duction of IL-6 and IL-8 induced by LPS in PDL cells but increased Akt and Erk1/2 phosphorylation in these cells. These results suggest that leptin acts as an inducer of IL-6 and IL-8 in PDL cells and gingival fibroblasts.

It has been documented that SPA0355 exerts anti-inflammatory effects via the inhibition of nuclear factor¬kappaB activation. In present study, we investigated the inhibitory effects of SPA0355 on periodontitis in an animal model. Periodontitis was induced by ligation of the cervix of the 1st molar in the left mandible in rats. After ligature, the rats were randomly divided into four groups and topically applied with SPA0355 (0.5, 1, and 2%) or the vehicle alone once daily for 10 days. Body weight and food intake were measured daily throughout the experimental period. At day 10 post-ligature, the infiltration of inflammatory cells and distance of the cementoenamel junction (CEJ) to the alveolar bone crest (ABC) in the distal area of ligatured tooth were estimated histopathologically. No changes in body weight or food intake were found between the control and SPA0355 groups. The degree of inflammation was decreased in all three SPA0355 application groups. A decrease CEJ-ABC distance was observed in the 0.5% and 1% SPA0355 groups. These results indicate that SPA0355 inhibits the infiltration of inflammatory cells and alveolar bone resorption and suggests its potential as a therapeutic agent for periodontitis.

The purpose of this study was to investigate the effects of the secondary tasks such as sending text message (STM) and searching navigation (SN) on skin conductance level (SCL) and driving performance of relatively aged and high-experienced drivers. The s

In vitro 항산화 활성을 갖는 율피 추출물의 향장 소재 특성을 조사하였다. 율피로부터의 다양한 추출물 중 총 페놀성 화합물 함량은 60% 메탄올 추출물 및 에틸아세테이트 분획물이 각각 164.82 및 191.14 mg/g으로 가장 높은 것으로 나타났다. 또한, 상기 두 분획물에 의한 in vitro 항산화 활성(DPPH radical scavenging activity, lipid peroxidation 저해)은 농도 의존적으로 증가한다는 것을 확인하였다. 상기 두 분획물은 UV-B(290-320 nm) 영역에서 강한 UV 흡수도를 보여주었다. 특히, 율피 유래 두 분획물은 1000 μg/mL에서 42.88 및 33.02%의 elastase 저해 활성을 나타내어 우수한 주름 개선 특성을 가지는 것을 보여주었다. 아울러, 율피로부터의 60% 메탄올 추출물 및 에틸아세테이트 분획물은 피부 상재균에 대하 여서도 항균 활성을 지니는 것으로 나타났다. 이러한 결과들은 율피에서 추출될 수 있는 물질이 향장 산업 소재로서 활용될 수 있는 가능성을 제시하는 것으로 판단된다.

This study investigated changes in cognitive ability of intellectual and disability people by supplying two different condition of oxygen (21%, and 92%), during visual matching task. 10 males (average 28.7±4.7 years), and 13 females (average 34.1±7.2 years) in intellectual and disability people were selected as the subjects for this study. The each run consisted of four phases, i.e., Rest (2 min.), Adaptation (1 min.), Control (2 min.) and Task (2 min.). The analysis of cognitive performance with 92% oxygen administration when compared to 21% oxygen revealed that the response time decreased. This result supports the hypothesis that hyperoxic air increase oxygen saturation level in the blood, lead to more available oxygen to the brain, thus increase the ability of cognitive processing of intellectual and disability people.

Peripheral nerve injuries are very common in clinics and often result in severe functional deficits. The aim of this study was to evaluate the effect of treadmill running and electro-acupuncture on nerve regeneration and functional recovery of muscle activity following sciatic nerve crush injury in a rat model. A comparative study was conducted over 30 days on 60 adult male Sprague-Dawley rats grouped into sham control (C), electro-acupuncture (EA), treadmill (T), and treadmill plus electro-acupuncture (TEA). The left sciatic nerve was crushed for 30 sec using a hemostatic forceps and functional activity was evaluated with sciatic functional tests, nerve conduct velocity, muscle weight, and histology at 10, 20, and 30 days after injury. Muscle weight was significantly (P<0.05) increased between days 10 and 30 in the TEA group. In histology, the degree of damage was scored as C > TEA > T > EA, although necrosis and fibrosis of muscle was observed only in the TEA group. The EA and TEA groups showed rapid recovery with better myelinated axons on day 10. These results suggest that application of the TEA method with balanced exercise is a useful treatment option for peripheral nerve injury regeneration and muscle activity.

The purpose of this study was to investigate the effects of the secondary tasks such as sending text message (STM) and searching navigation (SN) on skin conductance level (SCL) and deviation of vehicle speed during driving. The participants included 30 he

Strawberry powder was incorporated into Baikseolgi by substituting the non-glutinous rice flour in the range of 0-8% based on the total weight of the non-glutinous rice flour and the effects on physicochemical and sensory properties were investigated. pH decreased significantly with the higher amount of strawberry powder in the formulation whereas titratable acidity showed a reverse trend (p<0.05). Moisture content also decreased significantly with the increasing amount of strawberry. Lightness (L*-value) decreased significantly with higher strawberry powder concentration, indicating that the color of Baikseolgi became dark as also indicated by the visual observation. Redness (a*-value) and yellowness (b*-value), on the other hand, increased significantly with the substitution of strawberry powders up to 8% (p<0.05). Increases in strawberry powder concentration up to 8% in the Baikseolgi formulation significantly increased the intensities of sensory color, flavor, and taste attributes; on the other hand, the intensities of sensory moistness and chewiness decreased significantly (p<0.05). Results from the consumer test revealed that control received the highest acceptability scores in all attributes but 4% sample also obtained the competitive scores. Finally, Pearson correlation analysis revealed several very highly significant linear correlation between the means used to access physicochemical, sensory properties, and consumer preferences.

본 연구에서는 대표적인 퇴행성 신경질환인 알츠하이머성 치매에 대한 마늘 물, 100% 메탄올, 디 클로로메탄 추출물들의 acetylcholinesterase (AChE) 저해 및 신경세포 보호효과를 조사하였다. 마늘 디클로로메탄 추출물은 농도 의존적으로 AChE를 저해하는 것으로 나타났으며, IC50은 36.1 μg/mL로 나타났다. MTT reduction assay를 이용해 amyloid β protein (Aβ) 유도성 신경세포 독성에 대한 신경 세포 보호효과를 측정한 결과, 세 가지 마늘 추출물들은 대부분 40% 미만의 세포생존율을 보였고 이 결과는 Aβ 유도성 신경세포 독성보다 상대적으로 더 높은 세포독성을 보여주었다. LDH assay에 서는 마늘 물 추출물이 37%의 LDH 방출량을 나타내 200 μM의 vitamin C과 유사한 세포막손상 보 호효과를 보였다. 마지막으로 neutral red uptake assay를 실시한 결과, MTT reduction assay와 마찬가 지로 모든 마늘 추출물들에서 세포생존율의 감소를 확인하였으며 특히 디클로로메탄 추출물의 경우 현저하게 낮은 세포생존율을 나타내었다. AChE 저해활성을 갖는 마늘 디클로로메탄 추출물로부터 얻은 column fractionations에 함유된 생리활성물질을 탐색하기 위해 HPLC 분석을 실시하였으며, 마 늘 98:2 fraction의 LC-MS 분석을 통하여 allyl methyl disulfide, diallyl monosulfide, diallyl disulfide로 추정되는 물질군이 확인되었다.

The purpose of this study was to investigated correlation between personal aggression and skin conductance level during watching attack image. Twenty three male (2 1. 4土1. 8 years) college students participated in this experiment. A personal aggression of

자색고구마 추출물의 항산화 효과와 산화적 스트레스로 유도된 PC12 신경세포에 대한 보호효과에 대하여 연구하 였다. 자색고구마 추출물의 총 페놀함량은 44.25 mg/g, monomeric anthocyanin 함량은 2,394 mg/L로 나타났 다. 자색고구마 추출물의 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis-(3-ethylben-zthiazoline- 6-sulfonic acid) (ABTS) radical 소거활성, ferric reducing/antioxidant power (FRAP) 및 환원력은 농도 의존 적으로 항산화 활성이 증가하였다. MTT {3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyl-tetrazoliumbromide} reduction assay를 이용하여 자색고구마 추출물의 신경세포 보호효과를 측정한 결과, 세포 생존율이 두드러지게 증가하는 것으로 나타났다. 산화적 스트레스는 신경세포막 손상 정도를 증가시키기 때문에 lactate dehydrogenase (LDH) release assay와 neutral red uptake assay를 이용하여 세포막 손상 보호효과를 조사한 결과 자색고구마 추출물 처리구는 대조구에 비하여 산화적 스트레스로 유도된 세포막 손상 보호효과가 농도 의존적으로 나타났다. 따라서 자색고구마 추출물은 천연 항산화 소재 및 알츠하이머성 치매와 같은 신경퇴행성 질환의 예방 소재로서의 활용 가능성이 기대된다.

Present study investigates whether the syntactic constraints of English reflexives and pronouns originally proposed in Standard Binding Theory (SBT; Chomsky 1980, 1981, 1986) are well-reflected in written corpus data in British English by using the ICE-GB corpus. Four linguistic factors including structural relations between the reflexives/pronouns and their antecedents were used to analyze 1,000 sentences (400 reflexives and 600 pronouns) extracted from the ICE-GB corpus. The results demonstrated the following: i) The linguistic factors related to binding conditions showed structural differences between reflexives and pronouns in English; ii) English reflexives showed more cases of discourse binding (i.e., binding outside the sentential boundary) than the original expectation of SBT; iii) With the domain of sentential binding, structural constraints such as c-commanding and binding domain (Governing Category: SSC and TSC) were nearly violated with reflexives.

We studied the warming effect induced by Photovoltaic(PV) power plants in rural areas during summer daytime using a simple analytical urban meteorological model. This analysis was based on observed meteorological elements and the capacity of the PV power plant was 10 MWp. The major axis length of the PV power plant was assumed to be 1km. Data of the necessary meteorological elements were obtained from a special meteorological observation campaign established for a over a PV power plant. We assumed that the wind flowed along the major axis of the PV power plant(1 km). As a result, the air temperature on the downwind side of the PV power plant was estimated to invrease by about 0.47 °C.

Inflammation is the first response of the immune system to infection or irritation in our body. The use of medicinal plants has been widely applied as an alternative source for drug development. One of marine natural resources, the anti-inflammatory effect of Ishige sinicola ethanol extract (ISEE), was evaluated by using LPS-induced RAW 264.7 cell and mice model. As a result, the production of nitric oxide (NO) and pro-inflammatory cytokines (IL-6, IL-1β, TNF-α) were inhibited with increasing concentration of ISEE without any cytotoxicity. Furthermore, ISEE suppressed the expression of not only inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), nuclear factor-kappa B (NF-κB) p65, and mitogen-activated protein kinases (MAPKs), including extracellular signal-regulated kinase (ERK) 1/2, p38, and c-Jun N-terminal kinase (JNK) in a dose-dependent manner. In mice ear edema test, the formation of edema was reduced at the highest dosage of ISEE and the reduction of the number of infiltrated mast cells was observed in histological analysis. These results indicate that ISEE has a potent anti-inflammatory activity and can be used as a pharmaceutical material for many kinds of inflammatory disease.

We studied the distribution of air temperature using the high density urban climate observation network data of Daegu. The observation system was established in February 2013. We used a total of 38 air temperature observation points (23 thermometers and 18 AWSs). From the distribution of monthly averaged air temperatures, air temperatures at the center of Daegu were higher than in the suburbs. The daily minimum air temperature was more than or equal to 25℃ and the daily maximum air temperature was more than or equal to 35℃ at the elementary school near the center of Daegu. Also, we compared the time elements, which are characterized by the diurnal variation of surface air temperature. The warming and cooling rates in rural areas were faster than in urban areas. This is mainly due to the difference in surface heat capacity. These results indicate the influence of urbanization on the formation of the daily minimum temperature in Daegu.

The study investigates the validity of ‘subjecthood diagnostics’ in Korean proposed in the previous studies. Based on the studies on subjecthood diagnostics in Korean Single Subject Constructions (non-MSCs) and Multiple Subject Constructions (MSCs), the role of two subjecthood diagnostics―Honorific Agreement (HA) and Plural Copying (PC)―in these two constructions are examined through an empirical syntactic experiment. Seventy Korean native speakers participated in the experiment using acceptability judgment task designed to probe their intuition. The results show (i) that in the Non-MSCs, Honorific Agreement (HA) reliably seems to choose the subject (i.e., the only Nom-marked NP), whereas Plural Copying (PC) does not seem to pick out the subject in a less consistent manner; and (ii) that in the MSCs, neither Honorific Agreement (HA) nor Plural Copying (PC) seems to be a reliable subjecthood diagnostic. Possible reasons for these results are discussed.

The extensive construction works of container terminals progressed since 2006 was converted to small scaled construction works or reclaiming works since 2012 in Busan New Port area. To investigate changes in activity of otters with the change of construction work scales, the linear densities of spraints at 15 localities of 5 areas (I-V) near the Busan New Port construction areas were surveyed during the period from 2012 to 2016. As the results, the average linear density of spraints has a tendency to increase since 2014. That is, the linear densities of spraints have increased at the area II and IV where the reclaiming works have been progressed, although have decreased or unchanged in the areas Ⅰ, Ⅱ and Ⅴ where small scaled construction works have been progressed. Based on the fact that there were habitats at the Honamdo in the area II and the Yeondo in the area IV, otters seemed to restore their activities around the habitats as the center regardless of the reclaiming works.