Countries in the Chinese character cultural sphere share the Chinese Zodiac that assigns twelve animals to each year a person is born based on the order of arrival, so-called Tti. The twelve animals reflect the psychological characteristics of human life and are regarded as more special than other animals. Thus, the animals are used in idiomatic expressions as a vehicle to more properly describe human feelings and thought. This study therefore analyzed the semantic features of the twelve animals to explore the Chinese perception about the animals. The study result can be summarized as below: The representative semantic features of the twelve animals are as follows: [Villain], [Thief], [Misdeed], [Harmful], and [Heinous] for Rat; [Big] for Ox; [Villain], [Ferocious], [Cruel], [Heinous], [Foe], [Causing Fear], [Causing Risk], [Harmful], [Aggressor], and [Predator] for Tiger; [Agile] and [Quick] for Rabbit; [Emperor], [King], [High Status], [Authority], and [General] for Dragon; [Villain], [Aggressor], [Greedy], [Cunning], [Heinous], and [Vicious] for Snake; [War] and [Military] for Horse; [Weak], [Sacrifice], and [Dangerous Situation] for Sheep; [Nominal] for Monkey; [Small], [Slight], [Trifling], and [Useless] for Rooster; [Shabby], [Vulgar], [Bad], and [Foolish] for Dog; and [Shabby], [Vulgar], and [Wicked] for Pig. The negative semantic features were dominant in all animals except the dragon, which is consistent with a tendency that the animals are generally used to emphasize the negative aspects of a person. The semantic features of the animals are also presented in various domains of action, psychology, personality, morality, size, episode, speed, status, position, geographical features, attitude, shape, living, means, situation, etc.

목적: 국민건강영양조사 제7기(2016~2018) 원시자료를 이용하여 관절성 질환이 안질환에 영향을 미칠 수 있는지 와 그 연관성 정도를 파악하고자 하였다. 방법: 국민건강영양조사 제7기(2016~2018) 자료 중 관절성 질환과 안과 질환 진단여부에 응답한 만 50세 이상 의 성인 총 3,243명을 대상으로 두 질병간의 연관성을 분석하였으며, p<0.050인 경우 유의한 것으로 판단하였다. 결과 : 백내장, 녹내장, 황반변성의 주요 3대 안과 질환은 관절염 및 골관절염과 유의한 관련성이 있었다. 모든 변수를 보정한 상태에서 관절염은 1.296배(95% CI: 1.054~1.594) 정도 백내장의 위험을 증가시키는 것으로 나 타났으며, 황반변성은 2.413배(95% CI: 1.172~4.968) 위험을 증가시키는 것으로 나타났다. 또한 골관절염은 2.758배(95% CI: 1.342~5.668) 황반변성의 위험을 증가시키는 것으로 나타났다. 관절염과 골관절염은 녹내장에 영향을 미치지 않는 것으로 나타났다. 결론 : 관절염과 골관절염은 황반변성의 위험을 증가시키는 것으로 나타났고, 관절염은 백내장에도 영향을 미 치는 것으로 나타났다.

목적: 20~70대 성인을 대상으로 각막굴절력이 굴절이상과 동공크기에 미치는 영향에 대해서 확인하고자 하였다. 방법 : 안과질환과 각막굴절교정술 경험이 없는 근시안 그룹(831안, 34.55±13.17세, -2.28±1.37 D), 원시 안 그룹(369안, 47.20±12.24세, +1.22±0.72 D)이 본 연구에 참여하였으며, I-Profilerplus를 사용하여 대상안 의 각막굴절력과 동공크기 및 원점굴절도를 측정해 분석하였다. 결과 : 각막굴절력은 근시안 그룹이 원시안 그룹 보다 약 0.35 D 정도 유의하게 컸으며, 근시안과 원시안 및 전체 굴절이상 그룹에서 원점굴절도가 마이너스(-) 방향으로 높을수록 유의하게 증가하였다(p<0.050). 동공크기 는 근시안 그룹이 원시안 그룹에 비하여 약 0.40 mm 정도 유의하게 컸고 근시안과 원시안 및 전체 굴절이상 그 룹 모두에서 원점굴절도가 마이너스(-) 방향으로 높을수록 동공크기가 컸으며(p<0.050), 근시안과 원시안 그룹을 포함하는 전체 굴절이상 그룹에서 각막굴절력이 플러스(+) 방향으로 클수록 동공크기는 유의하게 증가하였다 (p<0.050). 결론 : 각막굴절력은 굴절이상과 동공크기 측정값에 영향을 주는 것을 확인하였으며, 이 연구 결과는 굴절이상 종류에 따른 동공크기 차이를 이해하는데 도움이 되는 기초자료가 될 것으로 생각한다.

The injection molding process is a process in which thermoplastic resin is heated and made into a fluid state, injected under pressure into the cavity of a mold, and then cooled in the mold to produce a product identical to the shape of the cavity of the mold. It is a process that enables mass production and complex shapes, and various factors such as resin temperature, mold temperature, injection speed, and pressure affect product quality. In the data collected at the manufacturing site, there is a lot of data related to good products, but there is little data related to defective products, resulting in serious data imbalance. In order to efficiently solve this data imbalance, undersampling, oversampling, and composite sampling are usally applied. In this study, oversampling techniques such as random oversampling (ROS), minority class oversampling (SMOTE), ADASYN(Adaptive Synthetic Sampling), etc., which amplify data of the minority class by the majority class, and complex sampling using both undersampling and oversampling, are applied. For composite sampling, SMOTE+ENN and SMOTE+Tomek were used. Artificial neural network techniques is used to predict product quality. Especially, MLP and RNN are applied as artificial neural network techniques, and optimization of various parameters for MLP and RNN is required. In this study, we proposed an SA technique that optimizes the choice of the sampling method, the ratio of minority classes for sampling method, the batch size and the number of hidden layer units for parameters of MLP and RNN. The existing sampling methods and the proposed SA method were compared using accuracy, precision, recall, and F1 Score to prove the superiority of the proposed method.

The army is concerned about the decrease in enlistment resources due to the low birth rate and the weakening of military combat power due to the shortening of the military service period. Now, the military's quantitative growth is no longer limited and it is a time for qualitative growth. To this end, the Army has been applying the Israeli learning method Havruta to recruit training to improve the quality of training since 2019. After applying Havruta, several scholars have studied the effect of recruit training applying Havruta. As a result, it was verified that recruit training applying Havruta improves the inner motive, creativity, and military service value of trainees. This study investigated how trainees' inner motive, creativity, and military service value affect their satisfaction and achievement. In addition, it was studied whether the effect of recruit training applied with Havruta on achievement differs according to the educational background (high school graduate or higher) and military family (professional soldiers within 4th degree) of the trainees. To this end, a survey was conducted on 472 recruits, and the structural relationship between each variable and the moderating effect were analyzed using the structural equation model. As a result of the study, military service value did not affect training satisfaction. Also, there was a difference in the effect of creativity on training satisfaction according to the educational background of new recruits, and there was a difference in the effect of military service value on training satisfaction and training achievement according to military family members. The purpose of this study is to contribute to the improvement of the army's recruit training development plan and effective training system.

The biological efficiencies of promising Pleurotus spp. were evaluated. Pleurotus ostreatus, Pleurotus tuberregium,and Pleurotus sajor-cajuwere investigated at temperatures of 22oC, 20oC, and 18oC to determine their ability to adapt to temperatures that are likely to be found in subtropical regions. The experiment was conducted using a substrate comprising Popular sawdust 60% + cotton seed 20% + beet pulp 20% under a relative humidity of 65%. The results indicated that there were significant differences in terms of biological efficiency between the species: P. tuber regium 128.84% at 22oC, P. ostreatus 108.41% at 22oC, and P. sajor-caju is 80% at 20oC. The common temperatures at which all species showed the highest biological efficiencies were 22oC and 20oC. Therefore, the production of the evaluated species was equal to or surpassed biological efficiencies reported in tropical environments, thereby demonstrating a potential opportunity to adapt to tropical environments without compromising quality standards.

Wolfiporia cocos is an edible fungus commercially cultivated in Asia. To investigate metabolic changes of W. cocos mycelia under both light and dark culture conditions, gas chromatography mass spectrometry (GC-MS) and high-performance liquid chromatography (HPLC) analyses were performed. In terms of the total amount of sugars, alcohols, amino acids, organic acids, fatty acids, and purines, there no significant differences between the W. cocos mycelia cultivated under light (L) or dark (D) conditions (p < 0.05). However, there were some differences with respect to the production of particular sugars and proteins. The levels of trehalose (L: 17.2 ± 0.3% vs. D: 13.9 ± 1.6%), maltose (L: 0.9 ± 0.1% vs. D: 0.3 ± 0.1%), turanose (L: 0.7 ± 0.2% vs. D: 0.1 ± 0.1%), glutamine (L: 1.6 ± 0.3% vs. D: 0.7 ± 0.2%), and proline (L: 0.3 ± 0% vs. D: 0.1 ± 0%) were all significantly higher under light condition (p < 0.05). In contrast, the levels of galactose (L: 13.7 ± 1.2% vs. D: 17.6 ± 2.0%), aspartic acid (L: 0.6 ± 0.1 % vs. D: 0.9 ± 0.1%), cystathionine (L: 0.6 ± 0.1% vs. D: 0.8 ± 0 %), and malic acid (L: 0.7 ± 0.1% vs. D: 1.2 ± 0.1%) were higher under the dark condition. It is worth noting that the amount of pachymic acid, a pharmaceutically active compound of W. cocos, was 1.68 times greater under the light condition (p < 0.05).

Following the previous study, the toxicity of a single subcutaneous administration of the Thyrokitty injection (I-131) and the side effects that may occur at therapeutic doses were confirmed. The Thyrokitty injection (I-131) was administered subcutaneously once at a dose of 0, 2.0, 6.0, and 18.0 mCi/kg, 5 male and female rats per group, and mortality, general symptom observation, and weight measurement were performed for 2 weeks, followed by observation of autopsy findings. There were no deaths, and no statistically significant weight change was observed. Mild hair loss, fissures, and crusting were observed by general symptom observation, but it was not a toxic change related to the Thyrokitty injection (I-131). Gastric atrophy and a decrease in the size of the spleen were observed by the autopsy. As a results of single subcutaneous administration of the Thyrokitty Injection (I-131) to rats at a maximum dose of 18.0 mCi/kg, a decrease in the size of the spleen and gastric atrophy were observed as the dose of the Thyrokitty Injection (I-131) increased, which may be related to the test substance. No abnormal findings related to the Thyrokitty injection (I-131) were observed. Therefore, the approximate lethal dose of the Thyrokitty injection (I-131) was 18.0 mCi/kg or more. In addition, as reported for the treatment of feline hyperthyroidism with radioiodine (131I), side effects of the Thyrokitty injection (I-131) are expected to be extremely rare. Temporary dysphagia and fever may occur, but it will recover naturally. It should be administered with caution in cats with diseases such as urinary system, cardiovascular system, gastrointestinal system and endocrine system, especially with kidney disease. And it should not be used in cats who are pregnant, lactating, or likely. It is expected that the Thyrokitty injection (I-131) can be used for clinical treatment in Korea as a veterinary drug.

Radioiodine (131I) has been used for the treatment of feline hyperthyroidism since the 1990s in the USA and Europe, and it is recommended as the most effective treatment for feline hyperthyroidism because it has a high therapeutic effect, small side effects, and does not require anesthesia. In this study, the pharmacological properties of the Thyrokitty injection (I-131), which is being developed as a treatment for feline hyperthyroidism, using radioiodine (131I) as an active ingredient, was tested. The %cell uptake of the Thyrokitty injection (I-131) in FRTL- 5 thyroid cells was 0.410 ± 0.016%, which was about 18 times higher compared to Clone 9 hepatocytes, and it was decreased by 30.7% due to the competitive reaction with iodine (sodium iodide). In addition, the %cell growth of the FRTL-5 thyroid cells was reduced by 25.0% by treatment with the Thyrokitty injection (I-131). As a result of the tissue distribution test, the Thyrokitty injection (I-131) was distributed at the highest concentration at 0.083 hours (5 minutes) after subcutaneous administration to animals in most organs except the stomach, small intestine, large intestine, muscle and thyroid gland, and it was excreted mainly through the kidneys. The stomach and thyroid gland showed a typical distribution pattern observed when radioiodine (131I) was administered. In addition, about 78.45% of the total amount of excretion was excreted within 48 hours, of which more than 85% was excreted in urine. In conclusion, the Thyrokitty injection (I-131) has the same mechanism of action, potency, absorption, distribution, metabolism and excretion characteristics as radioiodine (131I) reported in connection with the treatment of feline hyperthyroidism. In the future, using the results of this study, it is expected that the Thyrokitty (I-131) could be safely used in the clinical treatment of feline hyperthyroidism.

Ticks and tick-borne pathogens are among the main sources of interest in veterinary medicine and public health. This review aimed to cover published data on tick species and their geographical distribution in Korea. Over 143 articles regarding ticks were published between 1966 and 2022, and reporting at least 29 species belonging to the family Ixodidae and five belonging to the family Argasidae. Among these, Haemaphysalis longicornis, H. flava, and Ixodes nipponensis were the main genera distributed nationwide, whereas Amblyomma was mostly identified in the southern region. Conversely, only a limited number of Argasidae ticks were present, including the genera Argas and Ornithodoros. Considering the changes in tick distribution patterns due to global warming, continuous nationwide monitoring of ticks is required.

Diabetic encephalopathy is a major complication with cognitive impairment and neurodegeneration in patients with type 1 or type 2 diabetes mellitus (DM). DM-induced glucolipotoxicity is a risk factor for Alzheimer’s disease–like phenotype, including amyloidogenesis, tau hyperphosphorylation, and neuronal apoptosis. Although the detailed mechanism underlying the pathogenesis of diabetic encephalopathy remains unclear, mitochondrial oxidative stress is emerging as a key factor for diabetic complications and neurodegeneration. A deeper understanding of the regulatory mechanism of mitochondrial oxidative stress under hyperglycemic conditions will provide insights into the development of therapeutic strategies for diabetic encephalopathy. Here, we review the role of mitochondrial oxidative stress in diabetic encephalopathy and the regulatory mechanisms by which high glucose induces the generation of mitochondrial reactive species oxygen species in neuronal cells. This review also summarizes the mitochondrial-dependent and -independent pathways (O-linked-N-acetylglucosaminylation, calcium, and glycogen synthase kinase 3β signaling) that regulate mitochondrial oxidative stress in a DM model.

Automatic question-answering is a classical problem in natural language processing, which aims at designing systems that can automatically answer a question, in the same way as human does. The need to query information content available in various formats including structured and unstructured data has become increasingly important. Thus, Question Answering Systems (QAS) are essential to satisfy this need. QAS aim at satisfying users who are looking to answer a specific question in natural language.Moreover, it is a representative of open domain QA systems, where the answer selection process leans on syntactic and semantic similarities between the question and the answering text snippets. Such approach is specifically oriented to languages with fine grained syntactic and morphologic features that help to guide the correct QA match. Furthermore, word and sentence embedding have become an essential part of any Deep-Learning-based natural language processing systems as they encode words and sentences in fixed-length dense vectors to drastically improve the processing of textual data. The paper will concentrate on incorporating the sentence embedding with its various techniques like Infersent, ElMo and BERT in the construction of Question Answering systems, and also it can be used in game play.

James S. Gale (1863-1937), a Protestant missionary to Korea (1888~1927), was well-known for his extensive and profound influence on Korean studies and for his translation of the Cloud Dream of Nine (九雲夢), which was the first Korean classical novel translated into English by a Westerner. However, it is not well-known that Gale published a translation of the Great Learning (Daxue, 1924) and arranged for the publication of the Mean of the Doctrine, the Analects and Mencius. This is because it was known that Gale regarded Chinese characters and Confucian scriptures as obstacles to establishing the Christianity during his early period of mission in Korea. This paper examined the change of Gale’s perspective of Chinese characters and the characteristics of Gale’s Daxue. The analysis compares Gale and James Legg in their translations of the Chinese characters ‘命,’ ‘天,’ ‘明’ and ‘君子’ He employed the pure Korean word ‘Hananim’ for ‘God’ from a traditional Korean religion and its Korean etymology, while he rejected the use of Sino-Korean ‘Sangje上帝’, or ‘Chunju天主’ in the Korean Bible. Gale subsequently translated Daxue from a Korean point of view. However, his Korean perspective is mingled with Christianized concepts, which are illustrated in his translation of ‘命’ as ‘God’s command’ ‘天’ as ‘God’ ‘明’ as ‘glory,’ and ‘君子’ as ‘good man’ and ‘godly man.’

This study addresses the lack of comprehension data in second language acquisition research by focusing on English existential there-constructions (ETCs) with a locative extension (e.g., there is an X on the Y). The post-copular noun X used in the present study consisted of two types: actual and nonsense. Participants included 40 native speakers, as well as 40 advanced and 40 intermediate Korean learners of English, who completed an online picture selection task. In one picture, X was placed on the nearby Y; in another picture, X was placed on the far Y. The choice of both pictures was the correct response because ETCs are used to describe the existence of something regardless of its distance. There was a statistically significant relationship between English proficiency and the interpretation of ETCs. However, there was no relationship between the noun type and the interpretation of ETCs. In the Korean English curriculum, the distinction between expletive there and locative there must be emphasized.