Purpose: This was a qualitative study using a phenomenological research method. It was conducted to investigate the essential meaning of nursing students’ experiences participating in simulation education with standardized patients. Methods: This study’s research participants included 16 senior employees in the nursing department of two universities. They had experiences participating in simulation education with standardized patients. This study was conducted from June 1 to December 31, 2021, and the data were analyzed using Colaizzi’s (1978) phenomenological method. Results: After analyzing the meaning of simulation experiences with the standardized patients, 101 meaning formations were deduced. From this, 13 theme, 4 theme clusters and 2 categories—effective lesson, tasks to solve. Conclusion: Simulation with standardized patients is a recent approach that has been actively applied in simulation-based learning in nursing colleges. This study conducted qualitative research on students’ experiences with standardized patients and analyzed essential meaning of the experiences. Therefore, it is recommended that simulation education content with standardized patients is developed. This can be achieved by optimizing the advantages of standardized patients with various clinical cases in other subjects besides psychiatry.

본 연구는 국내외 수중레저활동 관련 법률을 분석하여 국내 수중레저법에 대한 개선방안을 다음과 같이 제안한다. 첫째, 수중 레저활동자는 ‘수중레저사업자로부터 계약을 통해 수중레저활동 서비스를 제공받으며 수중레저활동을 하는 사람’으로 개정되어야 한다. 둘째, 수중레저활동구역을 설치하는 주체는 ‘수중레저사업자 및 수중레저활동자 등’으로 확대되어야 한다. 셋째, 레저 테크니컬 다이빙은 나이트록스 또는 혼합 가스 등을 사용하므로 가스 종류가 명확히 기재된 스티커 또는 밴드를 부착하도록 규제가 추가되어야 한다. 넷째, 다이빙 필수 장비에 수면표시부표(SMB)를 추가하고 공기통에 대한 일상 관리 및 정비방법에 대한 규제조항이 추가되어야 한다. 다섯째, 수중레저활동자의 다이빙 보험가입을 적극 권유하도록 제도화 할 필요가 있다. 이외에도 수중레저활동자의 안전을 확보하기 위해 수중레저사업자의 응급절차와 다이빙 가이드라인을 구체적으로 명시할 필요가 있다.

IgG4 연관 질환은 다양한 조직의 섬유 경화성 반응과 연관되어 IgG4 양성의 형질세포와 임파구가 침착되는 염증 반응을 특징으로 하는 전신 침범 자가면역 질환이다. 이 중 IgG4 연관 경화성 담관염은 IgG4 연관 질환의 담관 침범을 말한다. IgG4 연관 경화성 담관염에 대한 대부분의 증례 보고는 단기간의 임상 경과만을 보고하였고 이 단기간의 경과의 대부분은 스테로이드 치료 후 담도 협착과 황달의 호전을 보였다. IgG4 연관 경화성 담관염의 장기적 예후와 자연 경과는 아직 잘 보고되지 않았으며 국내에서는 아직까지 IgG4-SC 환자가 간경변으로 진행되었다는 보고는 없다. 저자들은 IgG4-SC 환자가 제대로 치료를 받지 않고 오랜 시간 지났을 때 자연 경과로서 비대상성 간경변으로 진행하고 더 이상 스테로이드에 반응하지 않은 1예를 경험하여 문헌고찰과 함께 보고하는 바이다.

The structure of nitrogen adsorption complex of fully dehydrated Cd2+ ion exchanged zeolite-X, |Cd46(N)18|[Si100Al92O384], was determined in the cubic space group Fd3 at 21(1) ℃ [a = 24.863(4) ] by single crystal X-ray diffraction analysis. The crystal was prepared by ion exchange in a flowing steam of 0.05 M aqueous solution Cd(NO3)2 : Cd(O2CCH3)2 = 1:1 for five days, followed by dehydration at 500℃ and 2×10-6 Tor. for two days, and exposured to 100 Tor. zeolitically dry nitrogen gas at 21(1) ℃. The structure was determined in atmosphere, and was refined within F0 〉 4Σ(F0) using reflection for which the final error can appear in indices R1 = 0.097 and wR2 = 0.150. In this structure, Cd2+ ions occupied four crystallographic sites. Nine Cd2+ ions filled the octahedral site I at the centers of hexagonal prisms (Cd-O = 2.452(16) a). Eight Cd2+ ions filled site I' (Cd-O = 2.324(19) a). The remaining 29 Cd2+ ions are found at two nonequivalent sites II (in the supercages) with occupancy of 11 and 18 ions. Each of these Cd2+ ions coordinated to three framework oxygens, either at 2.159(15) or 2.147(14) a, respectively. Eighteen nitrogen molecules were adsorbed per unit cell and three per supercage.

The structure of a carbon monoxide sorption complex of dehydrated fully Ca2+-exchanged zeolite X, |Ca46(CO)27|[Si100Al92O384]-FAU, has been determined in the cubic space group Fd 3 at 21℃ (a = 24.970(4) ) by single-crystal X-ray diffraction techniques. The crystal was prepared by ion exchange in a flowing stream of 0.05 M aqueous Ca(NO3)2 for three days, followed by dehydration at 400℃ and 2×10-6 Torr for two days, and exposure to 100 Torr of zeolitically dry carbon monoxide gas at 21℃. The structure was determined in this atmosphere and was refined, using the 356 reflections for which Fo 〉 4Σ(Fo), to the final error indices R1 = 0.059 and wR2 = 0.087. In this structure, Ca2+ ions occupy three crystallographic sites. Sixteen Ca2+ ions fill the octahedral site I at the centers of hexagonal prisms (Ca-O = 2.415(7) a). The remaining 30 Ca2+ ions are found at two nonequivalent sites II (in the supercages) with occupancies of 3 and 27 ions. Each of these Ca2+ ions coordinates to three framework oxygens, either at 2.276(10) or 2.298(8) a, respectively. Twenty-seven carbon monoxide molecules have been sorbed per unit cell, three per supercage. Each coordinates to one of the latter 16 site-II Ca2+ ions: C-Ca = 2.72(8) a. The imprecisely determined N-C bond length, 1.26(14) a, differs insignificantly from that in carbon monoxide(g), 1.13 a.

Mechanical properties of nanocrystalline Al-5at.%Ti alloy were investigated through high temperature compression test. Al-5at.%Ti nanocrystalline metal powders, which had finer and more equiaxed shape than those produced at room temperature, were produced by mechanical alloying at low temperature. The powders were successfully consolidated to 99fo of theoretical density by vacuum hot pressing. XRD and TEM analysis revealed that intermetallic compounds formed inside powders and pure Al region with coarse grains formed between powders, especially at triple junction. Mechanical properties in terms of hardness and strength were improved by grain size refinement, but ductility decreased presumably due to the formation of the weak interfaces between Al pool and powders.

본 연구는 생쥐의 난소 및 정소 조직에서 발달 단계에 따라 나타나는 일주기성 clock유전자의 발현과 단백질의 발현 양상을 알아보고자 하였다. 생쥐의 난소 및 정소에서 일주기성 변화와 연관된 유전자(Period1(Per1), Period2(Per2), Period3(Per3), Cryptochromel(Cry1), Cryptochrome2 (Cry2), Clock, Bmall)와 시교차 상핵에서 분비되어 표적 조직 또는 기관으로 전달되는 물질로 알려진