The purpose of this study was to evaluate the anti-atopic-dermatitis effect of Angelica keiskei extract using a DNFB-induced animal model of atopic-dermatitis symptoms. A. keiskei was prepared via extraction with DW, 50% ethanol, and 100% ethanol in addition to fresh juice. All the extracts reduced the thickness levels of the ears and ear epidermis against swelling by DNFB inducement, especially in the aqueous-extract-treated group. The mRNA expressions of matrix metalloproteinases (MMPs), however, were not observed, which may indicate that Angelica keiskei extract alleviates the atopic-dermatitis symptoms in an MMP-independent manner. Finally, the level of the inflammatory cytokine IL-4 was inhibited only in the juice-treated group, although the IL-13 level was inhibited in the juice-, 50%-ethanol-extract-, and 100%-ethanol-extract-treated groups in a dose-dependent manner, and was not inhibited in the aqueous-extract-treated group. Taken together, these results suggest that Angelica keiskei extract has an inhibitory effect on atopic dermatitis, and may be a useful biomaterial for the development of cosmeceuticals.

This study was performed to observe the effects of the feeding physiological activity substance in Cordyceps militaris hot-water extract intake on the improvement of lipid components and metabolic enzyme activities in the serum of dietary hyperlipidemic rats (SD strain, male) fed the experimental diets for 5 weeks. The concentrations of cholesterol (total cholesterol, β-lipoprotein, LDL-cholesterol, free cholesterol and cholesteryl ester), atherosclerotic index, triglyceride (TG), phospholipid (PL) and blood glucose in sera were remarkably lower in the Cordyceps militaris extract intake group than in the hyperlipidemic rats. In the ratio of HDL-cholesterol concentration was higher percentage in the Cordyceps militaris extract intake group than in the hyperlipidemic rats. The activities aminotransferase (AST, ALT) in sera were rather lower in the Cordyceps militaris extract administration than in the hyperlipidemic rats. From the above research, Cordyceps militaris extract were effective on the improvement of the lipid compositions in sera of dietary hyperlipidemic rats.

To investigate the anti-diabetic activity of ethanol and aqueous peel and seed extracts obtained from three different grape species (Cambell Early, MBA, and Kyoho), alpha-glucosidase inhibitory activity was examined. All extracts showed anti-diabetic activity, especially aqueous extract exhibited inhibitory effect above 70%. Thus, we used aqueous extract to check the potential hypoglycemic effects in a streptozotocin (STZ)-induced diabetic mice model. The results showed that the blood glucose level of STZ-induced diabetic mice decreased drastically after 3 hr when the aqueous extract of Cambell Early seed was treated to the mice model. The aqueous extract of Kyoho seed lessened blood glucose level by 60%. Together, these data indicate that extracts of grape peel and seed (aqueous or ethanol) may have potential in improving hypoglycemic effects in the diabetic symptoms, suggesting that further investigation on biomarker expressions should be rewarding.

신선초 추출물의 미백활성을 확인하고 이의 소재를 개발하기 위하여, tyrosinase 저해 활성 및 B16F10 세포주를 이용한 melanogenesis 저해능을 확인하였다. 그 결과, 신선초 50% 에탄올 추출물에서 B16F10 melanoma 세포의 멜라닌 생성을 억제하였다. Melanogenesis 억제 활성에 관련이 있는 분자마커의 확인을 위하여 RT-PCR에 의한 mRNA 발현 수준을 검토한 결과, 농도의존적으로 TYR, TYRP-1.

This study has intended to evaluate the subjective landscape of rural region using additive integration index calculation model in Seondong region, Gochang-gun, Jeollabuk-do, Korea. This study consists of the following three steps. First, this study defmed the rural landscape using survey and developed the estimating equation for rural landscape assessment index. Second, this study set up assessment units and assessment indicators, then estimated mean of representative landscape adjectives in accordance with them through residents-participatory evaluation. Third, this study calculated rural landscape assessment index using additive integration index calculation model, and evaluated subjective landscape of rural region in accordance with space types and landscape fields through mapping methodology. The results of this study can be described as follows: 1) satisfaction level for landscape in accordance with village (urban area and residential area) was very high; 2) satisfaction level was very high in both Ye-Jeon reservoir and Hakwon farm, representative landscape resources of the study area.

This study has intended to elicit the definition of rural landscape, to classify rural landscape type, and to develop the evaluation indicators of rural landscape, meeting the definition through delphi expert survey method. The survey was performed five times for 80 days by 20 experts. The delphi expert survey asked experts as follows: 1) to fill out open-ended questions regarding the definition of rural landscape, and classification of rural landscape types, and evaluation indicators; 2) to provide their own feasibility evaluation regarding the results of the previous answer; and 3) to reevaluate the feasibility of the definition, types, and indicators. Based on the survey results, this study has found the appropriate definition of rural landscape like the comprehensive complex of physical (objective) and nonphysical (subjective) factors characterizing natural and/or artificial scenary of rural village itself Also, this study has developed the evaluation indicators of rural landscape in accordance with space types and landscape units classified. The developed indicators included areal ratio, the degree of green naturality, the building coverage ratio for physical landscape field, and skyline, landscape adjectives, color landscape, semantic scale.

본 연구는 검은비늘버섯(CBPM-6호)의 선도유지 효과를 알아보기 위해 포장재(Wrap, PE, PP, AE)및 저장온도(1, 3, 6)을 달리하여 18일간 조사한 결과는 다음과 같다. 저장기간 중 포장재별 중량 감모율은 랩포장시 1에서 18일 후 3.17%이었으나, AF필름에서는 1.08%의 낮은 중량 감모율을 나타내었다. 색도는 저장기간이 연장될수록 명도와 황색도는 약간 증가하는 반면 랩 포장에서는 감소하는 경향을 나타내었다. 버섯 저장 전