This study has three objectives; 1) Evaluate major jobs of hospital workers based on Criterion(Notification number 2003-24 from Ministry of Labor in Korea) for high-risk job for musculoskeletal disorders(MSDs), 2) Relate each jobs in criterion and the hospital jobs considered in this study, 3) Relate each jobs in criterion and MSDs symptoms of hospital workers. A total 141 hospital jobs was evaluated. Most hospital jobs belonged to the numbers 2(Job with repetitive motions by neck, shoulder, elbow, wrist or hand more than 2 hours a day) and 4(Job with unsupported and deviated postures by neck or back more than 2 hours a day) from criterion. Most hospital workers participated in this study thought that the numbers 1(Job with keyboard or mouse work more than 4 hours a day) and 2 from criterion were associated with their jobs. Further study for hospital jobs should be focused on breaking down quantification levels of each numbers in the criterion due to its atypical and non-repetitive job characteristics of hospital jobs.

It has been very important to have an exact evaluation for risk factors in order to prevent WMSDs(Work-related Musculoskeletal Disorders). However, most WMSDs evaluation methods have always been some problems of possibilities associated with subjective evaluation. Therefore, this study tried to conduct a sort of usability analysis on three major evaluation methods(OWAS, RULA, REBA). Specifically, major subjects in the study consisted of three parts as follows; comparison of the results between experienced and inexperienced observers, analysis for the consistency of the results in terms of different evaluation times, and analysis for the consistency of the results in terms of different job characteristics(based on the part of the automobile). The results of the study were summarized as follows; 1) There was statistically significant difference of the results by RULA and by REBA between experienced and inexperienced observers. This might be due to the fact that experienced observers have had better ability to detect the important working posture during evaluation. However, the results by OWAS did not give any significantly different results between experienced and inexperienced observers, 2) All three checklists applied by experienced subjects did not show any single result significantly different in terms of different evaluation times. This might have to do with high intra-observer reliability from some of previous studies, 3) The five parts of an automobile were selected as five major jobs with different job characteristics in the automobile industry. Specifically, they were door part, front part(hood, etc.), inside part(dash board, seats, etc.), rear part(trunk etc.), and bottom part. All three methods did not show any significant differences for the results from each observers. Further study on this subject would eventually provide a sophisticated evaluating guidelines for WMSDs regarding determination of observer-specific evaluation, identification of repetitive number of evaluations for stable results for each checklist, determination of job-specific evaluation methods, and so on.

본 논문에서는 자기효능감(Self-efficacy belief)과 산업재해의 관계에 대한 분석을 수행하였다. 먼저 연구의 예비 단계에서는 크게 세 그룹 즉, 현장의 작업자, 현장 및 안전관련 자문업체에 근무하는 안전 관리자, 그리고 산업안전에 관계되는 정부기관 종사자 등을 대상으로 집중면접(Focus group interview)을 실시하였고, 이 집중면접의 결과를 근거로 하여 연구의 본 단계에서 적용될 설문지를 개발하였다. 본 설문지는 산업안전, 산업

This study tried to focus on nontraditional job that has not been studied in terms of the subjects associated with MSDs(Musculoskeletal Disorders). Specifically, dental procedure was the job to be analyzed in this study. An alternative method as well as a traditional method for viewing teeth while performing simulated dental procedures. Four graduated students did both methods(direct view and indirect view) as the subjects in this study. The method based on indirect view used a video camera and monitor to view the teeth. The experiment was conducted five times for each subject. The major findings in this study were as follows; 1) Job speed was increased with the repetitions for both methods, 2) Difference of Neck flexion between direct and indirect methods was statistically siginificant(Neck flexion for indirect method was dramatically decreased), 3) Difference of job speed between direct and indirect methods was statistically significant(Job speed for direct method was faster than that of indirect method), 4) Difference of error rate between direct and indirect methods was statistically significant(error rate for direct method was lower than that of indirect method), 5) Even though indirect method did not provide better performance in terms of job speed and error rate yet, it seemed to need a trade-off between two methods in the future since indirect method provided better working postures than that of direct method.

The psychosocial stress and musculoskeletal disorders(MSDs) have been one of major health problems for hospital workers. This study tried to understand the relationship between symptoms associated with MSDs and risk factors such as working posture, job stress, psychosocial stress and fatigue. A total number of 655 hospital workers participated in this study. Specifically, REBA was applied for evaluating working posture and a checklist prepared by KOSHA(Korean Occupational Safety and Health Agency) was used for symptom survey. A questionnaire from KOSHA was also used for collecting data associated with job stress, psychosocial stress and fatigue. All these data were formulated and modeled by path analysis which was one of major statistical tools in this study. Specifically, path analysis for the data we collected came up with several major findings. As a result, as for body part(neck), (waist) and (arms) the degree of risk of work posture measured with the use of job stress(KOSS), psycho-social stress(PWI-SF) and REBA is significantly more affected by fatigue than muscular skeletal disease related consciousness symptom. However, regarding bod(wrist), the degree of risk of work posture measured with the use of job stress(KOSS) and REBA is directly affected by muscular skeletal disease related consciousness symptom. This study is meaningful in that the study clarified the causal relations of the degree of risk of work posture, degree of fatigue, and muscular skeletal disease related consciousness symptoms by each body part measured with the use of work stress(KOSS), psycho-social stress(PWI-SF) and REBA.

본 연구는 직무 스트레스와 근골격계질환과의 관련성을 알아보기 위하여 단순작업과 반복 작업이 빈번하게 발생하는 전자제품 제조업에 대하여 고용 규모 30인 미만과 300인 이상의 사업장을 구분하여 실시하였다. 연구 대상자 311명은 근골격계질환 관련 자각증상과 한국인 직무 스트레스(KOSS)에 대해 설문 조사 방법을 이용하여 분석하였으며, 그 결과 한국인 직무스트레스(KOSS)영역에서 30인 이하의 사업장이 물리적환경, 직무요구, 직무자율성결여, 직무불안정, 조직체계, 보상부적절, 직장문화의 영역에서 불만족도가 300인 이상사업장에 비하여 스트레스가 높게 나타났다. 근골격계질환 관련 신체 부위별 증상자를 살펴보면 신체부위 목, 허리에 대한 증상 호소자가 가장 많은 것으로 나타났으며, 근로자들이 근무중 회사와의 갈등으로 격는 한국인 직무스트레스(KOSS)에서는 물리적환경, 직무요구, 직무자율성결여, 직무불안정, 조직체계, 보상부적절, 직장문화에 대하여 30인 미만 사업장 소속 근로자들의 스트 레스 노출정도가 높았다. 다만 KOSS부분에서 근로자들의 개인적인 성향을 나타내는 관계갈등부분은 약간의 차이로 300인 이상 고용사업장의 근로자에 대한 스트레스 노 출정도가 높았다. 이에 30인 미만 사업장과 같은 영세업종 근로자들에게 정신사회적 스트레스의 해소를 위한 예방 프로그램이 마련되어야 할 것이다.

The psychosocial stress and musculoskeletal disorders(MSDs) have been one of major health problems for hospital workers. This study tried to understand the relationship between symptoms associated with MSDs and risk factors such as working posture, job stress, psychosocial stress and fatigue. A total number of 655 hospital workers participated in this study. Specifically, REBA was applied for evaluating working posture and a checklist prepared by KOSHA(Korean Occupational Safety and Health Agency) was used for symptom survey. A questionnaire from KOSHA was also used for collecting data associated with job stress, psychosocial stress and fatigue. All these data were formulated and modeled by path analysis which was one of major statistical tools in this study. Specifically, path analysis for the data we collected came up with several major findings. The risk scores from working posture based on REBA had indirect effects via fatigue factor(MFS) as well as direct effects on symptoms. The factors associated with job stress (KOSS) and psychosocial stress(PWI-SF) had significant effects on symptoms. Specifically, indirect effect of job stress factors via fatigue factors(MFS) had bigger than that of direct effect of job stress on symptom.

The psychosocial stress and musculoskeletal disorders(MSDs) have been one of major health problems for hospital workers. This study tried to understand the relationship between symptoms associated with MSDs and risk factors such as working posture, job stress, psychosocial stress and fatigue. A total number of 655 hospital workers participated in this study. Specifically, REBA was applied for evaluating working posture and a checklist prepared by KOSHA(Korean Occupational Safety and Health Agency) was used for symptom survey. A questionnaire from KOSHA was also used for collecting data associated with job stress, psychosocial stress and fatigue. All these data were formulated and modeled by path analysis which was one of major statistical tools in this study. Specifically, path analysis for the data we collected came up with several major findings. The risk scores from working posture based on REBA had indirect effects via fatigue factor(MFS) as well as direct effects on symptoms. The factors associated with job stress(KOSS) and psychosocial stress(PWI-SF) had significant effects on symptoms. Specifically, indirect effect of job stress factors via fatigue factors(MFS) had bigger than that of direct effect of job stress on symptom.

This study tried to identify the job stress characteristics of female bank workers and the relationship between their stress and symptoms associated with musculoskeletal disorders(MSDs). The total number of 587 female bank tellers have been participated in this study. Specifically, questionnaire surveys regarding job stress and MSDs symptoms were conducted. On the basis of the results from the survey using Korean version of job stress questionnaire with 24 questions, stress scores associated with job requirement and job flexibility were relatively high. The job stress levels regarding job demand, organizational system, occupational climate at the work place were relatively high for the full time workers while the job stress levels regarding insufficient job control, job stability, interpersonal conflict, lack of reward were relatively high for the part time worker. The workers with longer total work years had relatively high job stress associated with interpersonal conflict, and organizational system while the workers with longer work years at the current job had relatively high job stress associated with occupational climate. Also, the workers with longer working hours a day had relatively high job stress associated with job demand, interpersonal conflict, organizational system, and occupational climate. According to the relationship identified in this study, symptoms at the neck, shoulder, hand, low back. leg were associated with the stress levels in terms of job flexibility, interpersonal conflict, job requirement, job stability. In conclusion, female bank workers are exposed to job stress due to their specific job characteristics and there has been certain relationships between their job stress and MSDs symptoms.

최근 산업안전/보건분야에서 누적외상성질환(Cumulative Trauma Disorders： CTDs)과 직업성요통(Low Back Injury)과 같은 근골격계질환은 산업현장에서 어렵지 않게 발견할 수 있는 신종 산업재해의 일종이다. 특히 미국의 경우, 발생건수와 그로 인한 인적/물적 손실이 급격하게 증가되고 있는 것으로 나타나고 있다. 그러나 미국과 같이 근골격계질환의 폐해를 일찌감치 인식하고 그 해결방안을 연구해온 나라들에서는 현재 환자관리 및 인간공학적인 기준 등을 포함하는 예방지침들이 잘 정착되어 있는 실정이다. 우리나라의 경우에는 작업환경 등의 조건과 상황이 미국과 같은 구미 선전국과 비숫하고, 특히 제조업의 생산체계가 그런 나라들과 매우 유사하여 근골격계질환의 발생과 그로 인한 인적/물적 손실이 적지 않을 것이라고 예상할 수 있지만 아직까지 CTDs에 대한 전반적인 이해가 부족하고, 정확한 실태가 파악되지 못하였으며, 따라서 체계적인 관리 대책 또한 마련되어있지 않은 실정이다. 본 조사에서는 서울 근교의 수송기계관련 사업장의 작업들에 대한 작업자세에 중심을 둔 인간공학평가를 통하여 조사 작업의 근골격계질환에 대한 상대적인 위험도, 위험요인 등을 파악하고, 그에 따른 개선 대책의 방향을 제시하고자 하였다. 특히, 각 부위별 위험점수와 부위별 증상호소율의 상환분석결과, 작업자 개인적 수준에서는 통계적으로 유의한 차는 없는 것으로 분석되었으나, 부서별로 분석한 결과, 작업시 주로 사용하는 오른쪽 상지의 경우, 오른쪽 어깨, 팔꿈치, 손목 순으로 통계적으로 유의하게 관련이 있는 것으로 나타났다. 즉 증상호소율과 해당 신체부위의 위험도 점수는 서로 정적(positive)한 관계에 있는 것으로 나타났고, 상지 중 주로 사용하는 오른쪽 부담의 위험도 자세 점수와 증상호소는 비교적 높은 상관관계에 있는 것으로 나타났다. 따라서 이와 같은 인간공학적 분석결과는 향후 인간공학적인 개선대책의 개발 뿐만 아니라 의학쪽에서 근골격계질환을 접근하는 초기단계에서 매우 유용한 역할을 할 수 있으리라 생각된다.

Background: Ganoderma lucidum cultured on hulled barley was investigated as a potential natural source of antioxidants and antiinflammatory agents. Methods and Results: The yields from Ganoderma lucidum cultured on hulled barley water and ethanol extract were 17.69% and 25.77%, respectively. The antioxidant activity of Ganoderma lucidum cultured on hulled barley extracts was confirmed by various methods including assayss of 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azino-bis-(3-ethylbenzo thiazoline-6-sulfonic acid) (ABTS), nitrite radical scavenging, and Fe3+ to Fe2+ reducing power activity. The ethanol extract of Ganoderma lucidum cultured on hulled barley showed improved DPPH, ABTS and nitrite radical scavenging activity compared with the water extract. After treatment of RAW264.7 cells with Ganoderma lucidum cultured on hulled barley ethanol extracts, the cell viability compared with the control was 92.82%, even at a concentration of 3,000 ㎍/㎖. The ethanol extract inhibited reactive oxygen species (ROS) generation in RAW264.7 cells stimulated with H2O2, even at low concentrations. In addition, the ethanol extract showed an inhibitory effects on the production of lipopolysaccharide-induced nitric oxide (NO) in RAW264.7 cells. Conclusions: This study suggests that the extract of Ganoderma lucidum cultured on hulled barley is a potential source of natural antioxidants and anti-inflammatory agents.

Background : Lactuca sativa (LS) is a member of lactuca genus and the Asteraceae family. To its usual purpose as an edible leafy vegetable, lettuce has had a number of uses in ancient times as a medicinal herb. Depending on the variety, lettuce is an excellent source vitamin K and vitanin A. Methods and Results : The objective of this study is to find out the antioxidant and oxidative DNA damage prevention capacity of LS for both water and ethanol extract. The total phenolic and flavonoid contents have been estimated in this study. The extracts have been tested to assess the 1, 1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2ʹ -azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and nitrite scavenging activity. We have also evaluated the reducing power activity of LS. LS extracts showed a good radical scavenging activity on DPPH and ABTS free radical as concentration dependent manner. The IC50 values on DPPH radical scavenging activity were 0.75 mg/mL and 0.54 mg/mL for water and ethanol extract respectively. ABTS radical scavenging activity ranges from 38-89 % for water extract and 33-96% for ethanol extract. Although ethanolic extract showed a higher radical scavenging activity as compared to the water extracts. All the extracts exhibited reducing power activity, dose dependently. Moreover, when the DNA was treated with the extracts, supercoiled DNA was restored in a concentration-dependent manner. Conclusion : According to the results, we suggest that LS contains considerable amount of phenolic and flavonoid content and could be used as a source of natural antioxidant substances and oxidative DNA damage preventer.

Background : Achyranthes japonica Nakai (AJ) is a perennial herb with a wide distribution in East Asia including Korea, China, and Japan, and it is mainly used as a medicinal plant. In Korea, AJ has been widely used to control pain and improve symptoms in OA patients. AJ contains several important phytochemicals such as saponins, inokosterone, ecdysterone, and oleanolic acid bisdesmoside. Methods and Results : The aim of this work was to investigate the antioxidant and anti-inflammatory activities of fermented and ethanol extracts of Achyranthes japonica Nakai (AJ). The extracts showed strong reductive power and nitrite scavenging, hydroxyl radical scavenging, superoxide radical scavenging, and DNA damage prevention activities. Treatment of RAW 264.7 macrophages with AJ inhibited lipopolysaccharide (LPS)-induced NO secretion and iNOS expression without affecting cell viability. AJ also inhibited cyclooxygenase 2 (COX-2) expression, leading to the suppression of COX-2-derived prostaglandin E2 production. These inhibitory effects of AJ were accompanied by reduced production of tumor necrosis factor-α and interleukins (IL)-1β, -6, and -10. Furthermore, AJ suppressed LPS-induced phosphorylation of extracellular signal regulated kinase, c-Jun N-terminal kinase, and p38. Moreover, AJ inhibited malondialdehyde production and myeloperoxidase activity in LPS-stimulated RAW 264.7 cells. Conclusion : The antioxidant activity of plants is closely related to their medicinal properties and is widely used as a parameter to determine the bioavailability of medicinal plants. The antioxidant and biological activities of AJ extracts might be due to the synergistic actions of multiple bioactive compounds. It can be concluded that AJ extracts are a potential source of biologically important drug candidates.

Background : ROS produced by oxidative stress damaged endothelial cells, and cause a variety of vascular complications. In diabetic hyperglycemia state, ROS increase. The polyol pathway occur in diabetic complications, the excess glucose is absorbed into the polyol pathway when aldose reductase increased, NADPH changes it to sorbitol. Glutathione (GSH) removes ROS. GSH level is reduced by glutathione reductase, using NADPH as an electron donor. Activation of the polyol pathway decrease NADPH, and GSH also reduced. As a result, ROS is increased. In diabetic hyperglycemia state, Glycolysis increases. Effects of increased glycolysis, protein kinase C (PKC) is increased. NAD(P)H oxidase, stimulated by PKC-dependent pathway, increases ROS in the cell. In this study, we measured the ROS scavenging activity of 5 natural products (Lycii fructus, Astragalus membranaceus, Cassia Tora, Polygonatum odoratum, Rubus Coreanus), to confirm the efficacy as diabetic antioxidants. Methods and Results : We extracted 5 natural product by distilled water and ethanol. DPPH radical scavenging activity was significantly higher in Lycii fructus, Rubus coreanus. ABTS radical scavenging activity was better Rubus coreanus, Lycii fructus, Cassia Tora. In addition to, Rubus coreanus, Cassia Tora, Lycii fructus was comparatively higher reducing power activity than other natural products. And total phenolic and flavonoid contents were much higher in Rubus coreanus compared with other extracts. Conclusion : These results suggest that Lycii fructus, Rubus coreanus can be applied as diabetic antioxidant that prevent vascular complications caused by ROS.