This study aims to gain insight into society and culture in the 10th to 7th centuries B.C. by exploring the clothing in Assyria, which was the most powerful force in Mesopotamian civilization at the time. As a research method, literature and empirical studies were conducted in parallel, focusing on a total of 127 Assyrian artifacts held in domestic and foreign museums. The results of this study are as follows. The basic forms of Assyrian clothing are tunics and shawls. The tunics have short sleeves and are knee or ankle length with a special type of tassel decoration. They have a wide belt at the waist, and a decorative panel is attached vertically below with a strap. In addition to the basic clothing, there are loincloths and overskirts, with some having open right sides and fringe decorations to denote a higher status. The overskirt has a third or fourth-tier skirt structure with an open front and fringe decorations on the edges. Most military members, except for archers, wore knee-length tunics as uniforms. As for armor, they wore short-chest or knee-length coat-type lamella armor. Headwear mainly consisted of cylindrical hats and headband-type decorations. In the case of bracelets, mainly rosette-shaped decorations and simple ring-shaped bracelets with three or one turn were worn. For shoes, sandals were mainly worn, and soldiers mainly wore boots. As a result, each costume element is expressed in various ways depending on the wearer’s status, clearly showing Assyrian costume culture.
마비성 패류독소 중독증(paralytic shellfish poisoning; PSP)은 삭시톡신과 그 유사체로 오염된 패류를 섭취했을 때 발생하며, 저림, 구토 등의 증상에서부터 근육 마비와 심각한 경우 호흡 마비로 이어져 사망에 이를 수 있다. 독 성등가계수(toxic equivalency factors; TEFs)는 다양한 마 비성 패류독소의 독성을 표준화하여 위험성을 평가하는 데 사용된다. 마비성 패류독소를 검출하기 위해 사용되던 마우스 생체 실험(mouse bioassay; MBA)에 대한 윤리적 문제가 제기되면서 고성능액체크로마토그래피와 같은 기 기 분석법으로의 전환이 시도되고 있지만, 유사체들의 적절 한 TEF를 설정하기 위해서는 여전히 동물 모델을 통한 생 체 내 독성 데이터가 필수적이다. 본 연구에서는 동물 수를 줄이면서도 신뢰할 수 있는 경구투여 독성 결과를 얻기 위 해 삼단계 반응표면-경로 (three-level RSP) 설계를 사용했다. 인증 표준 물질을 이용하여 각 독소의 초기 용량과 조정 계 수를 결정하고 시험을 진행했으며, STX.2HCl, NeoSTX, dcSTX, GTX1&4, GTX2&3, dcGTX2&3의 반수치사량 (및 TEF) 값은 각각 451.3 (1.00), 306.5 (1.47), 860.9 (0.52), 644.5 (0.70), 915.3 (0.49), 2409.3 (0.19)로 나타났다. 도출된 TEF 값은 2016년 WHO에서 권고한 TEF 값뿐만아니라, 이 전에 보고된 경구 투여 반수치사량을 기반으로 한 TEF 값 과 강한 상관관계를 보였다. 본 연구는 마비성 패류독소 뿐 만 아니라 신규 미관리 해양생물독소에 대해 적절한 TEF를 설정하는 데 있어 삼단계 반응표면경로 설계를 윤리적 우 려와 신뢰할 수 있는 독성 데이터의 필요성 사이에서 효과 적으로 균형을 맞출 수 있는 방법으로 제안한다.
Hydrogen peroxide (H2O2) is widely used in bleaching treatments in the pulp and paper industry, in wastewater treatment, and as a food additive. However, H2O2 solutions are unstable and decompose slowly when subjected to external factors such as light, high temperatures, or metal compounds. Therefore, a simple and reliable method to measure the concentration of H2O2 is required for its proper use in various applications. We determined the concentration of an H2O2 solution by measurement at a single wavelength (249 nm) without any reagents or complex analytical procedures. In the present work, the measurable concentration of H2O2 was as low as 0.015 wt% (4.41 mM) and as high as 0.300 wt% (88.2 mM), with high linearity (99.99% at 249 nm) between the concentration of H2O2 and the optical density (OD) values. In addition, the method could be used to measure the concentration of H2O2 in a peracetic acid solution without interference from acetic acid and peracetate ion.
국립원예특작과학원에서는 밝은 화색과 안정적인 화형의 생 육이 우수한 빨간색 스탠다드 장미 품종을 육성하기 위해 진한 적색 스탠다드 장미 품종 ‘엔드리스러브(Endless Love)’를 모 본으로, 꽃잎수가 많고 안정적으로 가시가 적은 밝은 노란색 ‘페니레인(Penny Lane)’ 품종을 부본으로 인공교배하였다. 37 개의 교배실생을 양성해 1, 2, 3차에 걸친 특성검정 및 현장실증 을 통해 꽃이 크고 화형이 안정적이며, 재배안정성 및 생산성, 절화특성이 우수한 ‘원교 D1-390’을 최종 선발하였다. 2023년 ‘루비레드(Ruby Red)’로 명명하여 국립종자원에 품종보호출원·등록되었다. ‘루비레드’ 품종은 밝은 적색(R53C)을 가졌으 며, 꽃잎수가 32.8매, 화폭과 화고는 각각 10.9, 5.9cm로 대조 품종보다 크다. 절화장은 평균 71.7cm, 절화수명은 약 16.7일, 수량은 연간 168대/m2로 대조품종인 ‘레드스퀘어(Red Square)’ 대비 절화장이 길고 절화수명도 2배 이상 길며, 수확량도 1.4배 우수하다. 2023년 국내 육성 장미 품종 서울식물원 관람객 대상 공동평가회에서 스탠다드 장미 중 우수한 평가를 받았으며, 현 장 실증 결과 농가별로 균일하고 우수한 수량과 절화품질을 보 였다. 절화용 장미 ‘루비레드’ 품종은 밝은 적색과 우수한 화형 을 가지는 품종으로 해외 대체 품종으로 국내에서 많이 재배될 것으로 기대된다.
본 연구는 현 시대에 등장하는 일러스트레이션을 하인리히 뵐플린이 제시한 이론의 관점으로 접근하였으며, 시각적 회화와 촉각적 회화로 분류하여 해석하고자 한다. 일러스트레이션에 나타난 표현기법을 통합적으로 살펴보기 위해서 그림책작가를 선정한 후, 인 터넷 사이트나 출간된 서적 등에서 해당 작가의 작품 이미지를 수집하였다. 이들을 시각적 회 화와 촉각적 회화로 분류하였다. 윤곽선의 활용에 대한 부분이 가장 확실한 특징이라고 파악 하여, 윤곽선 활용 유무를 기준으로 분류하였다. 이들 중에서 작가가 각 작품마다 다른 스타일 을 추구하는 경우, 본 연구에서 수집한 작품을 중심으로 분류하였다.
본 연구는 서바이벌 게임에서 맵의 디자인 요소를 분석하고 표준화하는 것을 목표로 했다. 상 용 게임 10개를 조사하여 네 가지 주요 맵 유형을 파악하였고, 이를 바탕으로 유니티 에디터를 사용해 네 가지 유형의 맵을 개발 및 구현하였다. 무작위 위치에 장애물을 스폰하고, 타일 재 배치 시스템을 통해 맵을 무한대로 재배치할 수 있도록 했다. 또한, Update() 메서드를 조정해 타일 변위 오류를 해결했다. 마지막으로, ML 에이전트를 사용해 맵을 테스트했으며, 에이전트 가 환경을 탐색하고 장애물과 적대 대상을 인식 및 공격하며 각기 다른 네 가지 맵에서 효과 적으로 대응하는 모습을 확인했다.
Sweetpotato (Ipomoea batatas L.) is a globally important food crop that is susceptible to infestation with the root-knot nematode, Meloidogyne incognita, which causes substantial crop losses. Previous transcriptomic and proteomic analyses identified several genes that displayed differential expression patterns in susceptible and resistant cultivars in response to root-knot nematode (RKN) infection. As a result of previous study, RKN infection was confirmed in the RKN-susceptible sweetpotato cultivar Yulmi. Transcriptome analysis confirmed that among the genes that respond in this process, there are many genes related to ethylene biosynthesis. Therefore, in this study, we focused on the ACC oxidase (ACO) gene, the final enzyme of ethylene biosynthesis, and analyzed the expression patterns under various abiotic stress conditions. Using transcriptome data from our previous study, various expression changes in the four ACO genes used in this study were confirmed during RKN infection. The expression of G25011|TU41034 decreased during RKN infection compared to the untreated control, while the expression of G31097|TU51009, G28360|TU46486, and G15447|TU25395 genes increased in the early stages of RKN infection. Expressions of four ACO genes in leaves of sweetpoato were investigated under abiotic stress conditions such as wounding, high salinity, dehydration, and low temperature stress treatment. Expression of the G25011|TU41034 was significantly increased under abiotic stress conditions except low temperature. G31097|TU51009 was hardly expressed under abiotic stress conditions. Although the expression pattern of G28360|TU46486 and G15447|TU25395 was slightly different depending on the type of abiotic stress, an overall increase in expression was observed. It is expected that this study will be used as basic data on how ethylene biosynthesis responds not only to nematode infection but also to various abiotic stress conditions and will be helpful in functional studies of various crops.
InP quantum dots (QDs) have attracted researchers’ interest due to their applicability in quantum dot light-emitting displays (QLED) or biomarkers for detecting cancers or viruses. The surface or interface control of InP QD core/ shell has substantially increased quantum efficiency, with a quantum yield of 100% reached by introducing HF to inhibit oxide generation. In this study, we focused on the control of bandgap energy of quantum dots by changing the Zn/(In+Zn) ratio in the In(Zn)P core. Zinc incorporation can change the photoluminescent light colors of green, yellow, orange, and red. Diluting a solution of as-synthesized QDs by more than 100 times did not show any quenching effects by the Förster resonance energy transfer phenomenon between neighboring QDs.
Sprout products, such as broccoli, alfalfa, and cabbage, have positive health effects. Thus far, sprout foods have attracted attention owing to their good bioavailability. In particular, young broccoli sprouts exhibit anti-inflammatory, antioxidant, and anti-cancer effects. They contain 100 times more chemoprotective substances than adult broccoli. This study examined the anti-inflammatory effects of freeze-dried young sprout broccoli (FD-YB) in vitro using RAW264.7 macrophage cells. The FDYB powder antioxidant ability test showed that the radical-scavenging activity and superoxide dismutase enzyme activity increased in a dose-dependent manner. In addition, FD-YB was not cytotoxic to RAW264.7 cells, and nitric oxide production decreased after the FD-YB treatment of lipopolysaccharide-stimulated RAW264.7 cells in a dose-dependent manner. Furthermore, FD-YB significantly decreased the expression of inflammation-related proteins (Cyclooxygenase-2, Inducible nitric oxide synthase, and Prostaglandin E Synthase 2) and cytokines (Tumor necrosis factor- and Interleukin-6). In conclusion, FD-YB can be a potential nutraceutical for preventing and regulating excessive immune responses during inflammation.
Background: Aflatoxin B1 (AFB1) is a toxic metabolite generated by Aspergillus species and is commonly detected during the processing and storage of food; it is considered a group I carcinogen. The hepatotoxic effects, diseases, and mechanisms induced by AFB1 owing to chronic or acute exposure are well documented; however, there is a lack of research on its effects on the intestine, which is a crucial organ in the digestive process. Dogs are often susceptible to chronic AFB1 exposure owing to lack of variation in their diet, unlike humans, thereby rendering them prone to its effects. Therefore, we investigated the effects of AFB1 on canine small intestinal epithelial primary cells (CSIc). Methods: We treated CSIc with various concentrations of AFB1 (0, 1.25, 2.5, 5, 10, 20, 40, and 80 μM) for 24 h and analyzed cell viability and transepithelial-transendothelial electrical resistance (TEER) value. Additionally, we analyzed the mRNA expression of tight junction-related genes (OCLN, CLDN3, TJP1, and MUC2), antioxidant-related genes (CAT and GPX1), and apoptosis-related genes (BCL2, Bax, and TP53). Results: We found a significant decrease in CSIc viability and TEER values after treatment with AFB1 at concentrations of 20 μM or higher. Quantitative polymerase chain reaction analysis indicated a downregulation of OCLN, CLDN3, and TJP1 in CSIc treated with 20 μM or higher concentrations of AFB1. Additionally, AFB1 treatment downregulated CAT , GPX1, and BCL2. Conclusions: Acute exposure of CSIc to AFB1 induces toxicity, and exposure to AFB1 above a certain threshold compromises the barrier integrity of CSIc.
Salinity stress is a major threat to plant growth and development, affecting crop yield and quality. This study investigated the effects of different salinity levels on photosynthetic responses and bulb growth of Lilium LA hybrid “‘Serrada’.” Plants were irrigated with 1 L of 0, 200, and 400 mM NaCl solutions every two weeks for 14 weeks in a greenhouse. At the end of the cultivation period, the substrate pH decreased, and electrical conductivity increased with increasing salinity. Regardless of salinity levels, the days to flowering and number of flowers were similar among treatments. In contrast, the flower width, plant height, number of leaves, and leaf area decreased with increasing NaCl concentrations. Although there were no differences in the photosystem II (PSII) operating efficiency and maximum quantum yield of PSII, net CO2 assimilation rates (An) and stomatal conductance (gs) were significantly reduced at 200 and 400 mM NaCl solutions compared to the control. At 400 mM NaCl solution, bulb diameter and weight significantly decreased at the end of the experiment. These results suggest that bulb growth inhibition could be attributed to limiting photosynthetic rate and stem growth. This finding suggests that salinity mitigation is necessary to maintain plant growth and photosynthetic capacity in lily cultivation on salt-affected soils.
Helicobacter pylori are known as a causative agent of gastritis, gastric duodenum and peptic ulcer, and gastric cancer, and multiple drug use is associated with various side effects in patients. The discovery of antibacterial substances against H. pylori from Korean resource plants is an important substitute for antibiotics. 52 species of Korean resource plants were collected and extracted with 50% ethanol, and antibacterial activity against H. pylori was measured using the disk diffusion method. The toxicity of plant extracts to human gastric adenocarcinoma(AGS) cells was measured by MTT assay, and the level of IL-8 secreted when gastric epithelial cells were inoculated with H. pylori was measured. As a result of measuring the antibacterial activity of H. pylori, antibacterial activity was confirmed in 38 plant extracts. The plant species with the strongest antibacterial activity were Chrysanthemum indicum, Rheum rhabarbarum, Patrinia scabiosaefolia and Petasites japonicus. C. indicum was not cytotoxic to H. pyroli-infected AGS cells and showed anti-inflammatory effects. This study's results can be used to develop healthy, functional foods and medical materials.
Rehmannia glutinosa root and Saururus chinensis plant have been widely used in natural traditional medicines. This study was conducted to investigate the effect of the content of the main components of R. glutinosa root and S. chinensis plant by extraction method. The results of comparative analysis of extraction yield, total flavonoid, and polyphenol content by extraction method indicated that extraction yield had the best performance with hot water extraction for R. glutinosa and ultrasound-assisted extraction for S. chinensis. The total flavonoid and polyphenol content had the best performance with maceration extraction for R. glutinosa and ultrasound-assisted extraction for S. chinensis. ABTS and DPPH activity was excellent with maceration extraction for both R. glutinosa and S. chinensis. The analysis of the main components showed that maceration extraction was most effective for both S. chinensis and R. glutinosa. Specifically, maceration extraction of R. glutinosa yielded 1.5 times more than conventional ultrasound-assisted extraction.