The Republic of Korea has implemented an obligatory vaccination on major livestock breeds to prevent and eradicate nationwide foot and mouth disease (FMD) since the end of 2010. The government has executed massive serological survey to check the immune level of various herds after vaccination, and seropositive rates against FMD virus (FMDV) structural proteins can be measured to assess FMD immunity level. The purpose of this study is to investigate the FMDV serological level of every cattle breeding farm in the country and to determine whether there is a significant difference between groups classified by time, age, and management authority. A total of 5,781 serum samples was collected in 18 cattle breeding farms from 2020 to 2021, and the seropositive rates were measured using PrioCHECK FMDV Type O ELISA kit. Firstly, the cattle breeding farms were classified by which they are managed: the central government, the local government, and the private agency. Every management authority had a seropositive rate of 99.5% or higher. Secondly, the samples were divided into 6 to 12 months old, 12 to 24 months old, and 24 months or more. The 6 to 12 months old group in 2020 showed a significantly low seropositive rate of 98.1%, but it was improved by implementing the enhanced vaccination policy from 2021 to 100%. In summary, there are considerably high seropositive rates including all groups with time, age, and by which they are managed, which means the FMD vaccination in cattle breeding farms is well-managed.

This study aimed to provide directions and implications for a future program by analyzing studies on diabetes programs from 2000 to 2020. Among the studies with control and experimental groups, the selected studies included ones that provided intervention to patients with diabetes and ones that contained descriptive statistics. Sixteen studies were selected to verify the effectiveness and homogeneity of the data coding meta-analysis. The overall effect size in the diabetes program combined estimate was 0.398 (95% CI: 0.268, 0.425, p=0.000). Among the dependent variables, fasting blood glucose (－0.616) and glycated hemoglobin (－0.442) showed median effect sizes, but the effect of fasting blood glucose was not statistically significant. In terms of the study design, non-randomized control trials (NRCTs) (－0.543) was more effective than randomized control trials (RCTs) (0.719). Among, the counseling and self-management program (－3.241) showed a very large effect size. Furthermore, the cognitive-behavioral (－0.828) and self-management (－0.482) programs were also found to have a positive effect on lowering fasting blood glucose. As the importance of diabetes management increases, further studies based on RCT should be actively performed, and differentiated and specialized diabetes intervention plans need to be established.

근자에 건강불평등 문제가 한국사회의 중요한 사회문제로 대두되고 있다. 건강이 개인적 요인보다는 사회구조적 요인에 의해 더 크게 좌우된다는게 최근의 경험적 연구들의 보고이기 때문이다. 본 연구는 이 점에 착안해 부모의 교육수준(학력)이 아동의 건강에 미치는 영향을 탐색하였다. 특히, 공공 복지 수혜 여부를 기준으로 저소득층과 비저소득층의 차이를 비교분석하였다. 본 연구는 서울아동패널 조사(Seoul Panel Study of Children) 5차년도 자료를 사용하여 단순 빈도분석 및 기술통계 분석, 상관관계 분석, 다중 회귀분석 등을 실시하였다. 연구결과 저소득층 아동들은 부모의 학력이 아동의 건강에 영향을 미치는 것으로 나타났지만, 비저소득층 아동들은 그렇지 않은 것으로 나타났다. 특히, 저소득층 아동들의 경우 어머니의 학력이 높을수록 아동의 주관적 건강상태가 나빠지는 경향이 나타났다. 이는 주양육자인 어머니가 생계의 최전선으로 내몰릴 수밖에 없는 저소득층 가정의 경제상황과, ‘아이는 엄마가 키운다’는 한국의 가부장적 가족문화가 만들어낸 ‘돌봄 공백’이 그 이유라고 본다. 본 연구는 이같은 문제를 해결하기 위하여 양성평등적 돌봄 문화의 정립을 주장함과 동시에 섬세한 정책적 접근의 필요성을 주장한다. 예컨대 초등 돌봄에 대한 지원이 절실한 저소득층 가정을 위하여 지역사회 기반의 초등 돌봄 사회서비스(예컨대 서울시의 우리동네키움센터)의 도입 및 확대가 필요하다고 주장한다.

Germinated brown rice (GBR, Orysa sartiva L.) has been reported to have anti-obesity and anti-inflammatory effects. However, the mechanisms underlying these effects in adipocytes are not fully understood. Therefore, this study was conducted to explore the anti-inflammatory mechanisms of GBR on lipopolysaccharide (LPS)-stimulated 3T3-L1 adipocytes. 3T3-L1 adipocytes were pretreated with GBR extracts (0-20 mg/mL) 1 h before LPS stimulation. The mRNA expression of adipokines and Toll-like receptor 4 (TLR4) were measured by RT-PCR. The protein expressions of TLR4- related molecules were detected by western blotting and nuclear factor-κB (NF-κB) activation was measured. Our results showed that GBR extract dose-dependently inhibited mRNA expression of LPS-induced tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and monocyte chemoattractant protein-1 (MCP-1). GBR extract was found to inhibit LPS-induced mRNA expression of TLR4 and protein expression of both myeloid differentiation factor 88 (MyD88) and TNF receptorassociated factor 6 (TRAF6). Furthermore, GBR extract significantly inhibited extracellular receptor-activated kinase (ERK) phosphorylation and NF-κB activation. These results suggest that GBR extract has the anti-inflammatory effects on LPSinduced inflammation via inhibition of TLR4 signaling, includingthe ERK and NF-κB signaling pathways, in adipocytes.

This study examined the changes in antioxidant activity and contents of phenolic compounds inblanched, steamed, and autoclaved burdock root (BR). The total polyphenolic and flavonoids contents of raw and cooked BR were determined spectrophotometrically. The antioxidant activity of BR was measured using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2- azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and oxygen radical absorbance capacity (ORAC) assays. The main phenolic compounds in BR were quantified by HPLC (high performance liquid chromatography). Both blanching and steaming treatments significantly increased the antioxidant activities of BR in all groups (5 min, 15 min, and 30 min), whereas in autoclaving treatment, the 30 min treatment only showed an increase in the antioxidant activities of BR. The 30 min blanched BR exhibited the strongest DPPH and ABTS radical scavenging activities and possessed the highest total polyphenol and flavonoid phenolic contents. The 15 min-steamed BR showed the highest ORAC value. The main phenolic compound of the 15 min-steamed BR was CGA (chlorogenic acid). These results suggest that heat cooking methods, such as blanching and steaming, improve the antioxidant activity of BR by increasing the concentration of phenolic compounds.

Aloe-emodin (AE) is the major bioactive component in aloe and known to exhibit anti-inflammatory activities. However, it has not been elucidated whether its anti-inflammatory potency can contribute to the elimination of obesity. The aim of the current study is to investigate the effect of AE on toll-like receptor 4 (TLR4) pathways in the presence of lipopolysaccharide (LPS) in 3T3-L1 adipocytes. 3T3-L1 adipocytes were treated with AE (0-20 μM) for one hour, followed by LPS treatment for 30 min and then, adipokine mRNA expression levels were measured. Next, TLR4-related molecules were measured in LPS-stimulated 3T3-L1 adipocytes. AE significantly decreased the mRNA expression of the tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and monocyte chemoattractant protein-1 (MCP-1) in a dose-dependent manner. Moreover, AE suppressed TLR4 mRNA expression. Further study showed that AE could suppress the nuclear factor-κB (NF-κB) and phosphorylation of extracellular receptor-activated kinase (pERK). The results of this study suggest that AE directly inhibits TLR4/NF-κB/ERK signaling pathways and decreases the inflammatory response in adipocytes.

In this study, we described a suitable prioritisation scheme on these exempted drugs and established fundamental rules for residue monitoring enforcement in Korea. The principles of exempted materials were established. Based on these established criteria, 75 materials with high priority were selected and grouped. Among these materials, we have decided that 25 substances required further review for monitoring. Important factors for determining the priority for monitoring, product factor during the recent 4 years, veterinary medicine factors, including applied symptoms and component conditions, animal factors, including applied animals, and toxicological factors including acceptable daily intake (ADI), establishment of residual quantity permitted (MRL) or withdrawal periods, various provisory clauses and so on were set. High priority substances were acethylsalicylic acid, bromhexine, chlorpheniramine, and acetaminophen. In addition, we surveyed and provided analysis on the above mentioned materials in this study. The derived results will be suggested to the Animal and Plant Quarantine Agency (QIA) for development of guidelines of policy direction and the effective targeting for their monitoring program.

The aim of this study was to investigate school dieticians’ awareness of the necessity for nutritional education and job satisfaction via qualitative research. For this purpose, in-depth interviews were carried out with 10 school dieticians. Results revealed that all participants said that schools urgently need nutritional education, and dietary attitude and unbalanced eating habits were the most urgent matters to be addressed. They made various suggestions related to revitalization of nutritional education: turning dieticians into nutritional educators, improving awareness of teachers and parents, receiving training on appropriate teaching methods, and so on. In response to their tasks, they considered bargaining with vendors and examination foods as the most burdensome tasks. In response to questions about how participants were treated in their workplaces, all participants reported low job satisfaction due to excessive work, lack of promotion opportunities, and low salary. To improve this, participants recommended creating a task manual, strengthening their role as managers, increasing their salary, and so on. Therefore, institutional support is necessary for dieticians to efficiently handle their excessive workload. In addition, an educational environment where dieticians can effectively carry out nutritional education needs to be created.

In the present study, we conducted in-depth interviews with school dieticians and nutrition teachers to determine the local foods they were aware of and their experiences with local foods. We also aimed to obtain more detailed measures for local food vitalization and suggestions for improvements. In-depth interviews were performed with 8 school dieticians and nutrition teachers, who stated that local food vitalization was needed for school food services, because it could be a foundation for securing safefood products, student healthi mprovements, environmental protection, and the establishment of a general consumption market. However, they were aware of a higher number of disadvantages than advantages in school situations and indicated the deterioration of the quality of food products as the biggest disadvantage. The most-suggested measurement items for local food vitalization in schools included improvement of the food distribution system, expansion of education, information sharing, prevention of monopolies, improvement of food-product quality, and mass production. In addition, it was suggested that school dieticians and nutrition teachers should invest efforts in the development of excellent recipes and varied diets utilizing local foods. Therefore, system supplementation is urgently required in order for school food service officials, and consumers, to efficiently introduce and vitalize local foods. It is also necessary to foster an environment that encourages trust-based relationships with producers to maximize the effect of system supplementation. This would be the foundation for improving the health of students, improving food-service quality, nutrition management, and vitalization of the regional economy in the future, and will positively affect students’ food consumption patterns even after they become adults.

Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis and autoimmune polyradiculoneuropathy. Campylobacter jejuni is the most commonly identified infectious trigger for GBS. A sialic-acid containing lipopolysaccharide (LPS) of Campylobacter is thought to be involved in the triggering of GBS. The galE (UDPgalactoset- epimerase) gene of Campylobacter spp. is involved in the synthesis of LPS. In this study, we detected the galE gene in Campylobacter spp. responsible for triggering the onset of GBS. The PCR assay detected the presence of the gene in 14 of the 25 (56%) Campylobacter isolates from domestic chicken, 20 of the 28 (71.4%) Campylobacter isolates from imported chicken and 50 of the 51 (98%) Campylobacter isolates from human clinical samples. Also, the specific 497-bp region of galE sequence in Campylobacters responsible for triggering the onset of GBS was amplified from GBS patient. These results could provide evidence of the first GBS-related C. jejuni infection in Korea.

Halo coronal mass ejections (CMEs) originating from solar activities give rise to geomagnetic storms when they reach the Earth. Variations in the geomagnetic field during a geomagnetic storm can damage satellites, communication systems, electrical power grids, and power systems, and induce currents. Therefore, automated techniques for detecting and analyzing halo CMEs have been eliciting increasing attention for the monitoring and prediction of the space weather environment. In this study, we developed an algorithm to sense and detect halo CMEs using large angle and spectrometric coronagraph (LASCO) C3 coronagraph images from the solar and heliospheric observatory (SOHO) satellite. In addition, we developed an image processing technique to derive the morphological and dynamical characteristics of halo CMEs, namely, the source location, width, actual CME speed, and arrival time at a 21.5 solar radius. The proposed halo CME automatic analysis model was validated using a model of the past three halo CME events. As a result, a solar event that occurred at 03:38 UT on Mar. 23, 2014 was predicted to arrive at Earth at 23:00 UT on Mar. 25, whereas the actual arrival time was at 04:30 UT on Mar. 26, which is a difference of 5 hr and 30 min. In addition, a solar event that occurred at 12:55 UT on Apr. 18, 2014 was estimated to arrive at Earth at 16:00 UT on Apr. 20, which is 4 hr ahead of the actual arrival time of 20:00 UT on the same day. However, the estimation error was reduced significantly compared to the ENLIL model. As a further study, the model will be applied to many more events for validation and testing, and after such tests are completed, on-line service will be provided at the Korean Space Weather Center to detect halo CMEs and derive the model parameters.

During the last glacial–interglacial transition, there were multiple intense climatic events such as the Bølling–Allerød warming and Younger Dryas cooling. These events show abrupt and rapid climatic changes. In this study, the climate events and cycles during this interval are examined through wavelet analysis of Arctic and Antarctic ice-core 18O and tropical marine 14C records. The results show that periods of ~1383–1402, ~1029–1043, ~726–736, ~441–497 and ~202–247 years are dominant in the Arctic region, whereas periods of ~1480, ~765, ~518, ~311, and ~207 years are detected in the Antarctic TALDICE. In addition, cycles of ~1019, ~515, and ~209 years are distinct in the tropical region. Among these variations, the de Vries cycle of ~202–209 years, correlated with variations in solar activity, was detected globally. In particularly, this cycle shows a strong signal in the Antarctic between about 13,000 and 10,500 yr before present (BP). In contrast, the Eddy cycle of ~1019–1043 years was prominent in Greenland and the tropical region, but was not detected in the Antarctic TALDICE records. Instead, these records showed that the Heinrich cycle of ~1480 year was very strong and significant throughout the last glacial–interglacial interval.

Coronal Mass Ejections (CME), which originate from active regions of the Sun’s surface, e.g., sunspots, result in geomagnetic storms on Earth. The variation of the Earth’s geomagnetic field during such storms induces surface currents that could cause breakdowns in electricity power grids. Hence, it is essential to both monitor Geomagnetically Induced Currents (GICs) in real time and analyze previous GIC data. In 2012, in order to monitor the variation of GICs, the Korean Space Weather Center (KSWC) installed an induced current measurement system at SINGAPYEONG Substation, which is equipped with 765 kV extra-high-voltage transformers. Furthermore, in 2014, two induced current measurement systems were installed on the 345 kV high-voltage transformers at the MIGEUM and SINPOCHEON substations. This paper reports the installation process of the induced current measurement systems at these three substations. Furthermore, it presents the results of both an analysis performed using GIC data measured at the SINGAPYEONG Substation during periods of geomagnetic storms from July 2013 through April 2015 and the comparison between the obtained GIC data and magnetic field variation (dH/dt) data measured at the Icheon geomagnetic observatory.

There have been many suggestions and much debate about climate variability during the Holocene. However, their complex forcing factors and mechanisms have not yet been clearly identified. In this paper, we have examined the Holocene climate cycles and features based on the wavelet analyses of 14C, 10Be, and 18O records. The wavelet results of the 14C and 10Be data show that the cycles of ~2180-2310, ~970, ~500-520, ~350-360, and ~210-220 years are dominant, and the ~1720 and ~1500 year cycles are relatively weak and subdominant. In particular, the ~2180-2310 year periodicity corresponding to the Hallstatt cycle is constantly significant throughout the Holocene, while the ~970 year cycle corresponding to the Eddy cycle is mainly prominent in the early half of the Holocene. In addition, distinctive signals of the ~210-220 year period corresponding to the de Vries cycle appear recurrently in the wavelet distribution of 14C and 10Be, which coincide with the grand solar minima periods. These de Vries cycle events occurred every ~2270 years on average, implying a connection with the Hallstatt cycle. In contrast, the wavelet results of 18O data show that the cycles of ~1900-2000, ~900-1000, and ~550-560 years are dominant, while the ~2750 and ~2500 year cycles are subdominant. The periods of ~2750, ~2500, and ~1900 years being derived from the 18O records of NGRIP, GRIP and GISP2 ice cores, respectively, are rather longer or shorter than the Hallstatt cycle derived from the 14C and 10Be records. The records of these three sites all show the ~900-1000 year periodicity corresponding to the Eddy cycle in the early half of the Holocene.

The importance of atmospheric conditions for the assessment of an air pollution situation has been demonstrated by their influence on the various compartments of an air pollution system, comprising all stages from emission to effects. Especially, air pollutants dispersion phenomenon are very sensitive according to wind data. But the discussions of how to apply representative meteorological data in air pollution dispersion model are not frequent in Korean environmental assessment processes. In this study, we investigated the difference of air pollutants dispersion phenomenon using U.S EPA ISCLT3 model according to applying the different meteorological data observed at two points for Seongseo industrial complex of Daegu. Two points are the spot site of Seongseo industrial complex and Daegu meteorological observatory. The winds speed of the spot site were smaller than those of Daegu meteorological observatory. In the winter season, the differences came to about 64% for the period(1 February 2001～31 January 2002). Wind directions were also fairly different at two points. The air pollutants dispersion phenomenon estimated from our numerical experiments were also fairly different owing to the meteorological conditions at two points.