It is necessary to understand of temporal and spatial dynamics by establishing a periodical monitoring system for theproper management in small brown planthopper (SBPH). A dataset is including the number of SBPHs by location, collectionmethod [aerial collection net (AeCN) or light trap (LT)] and period (May~Aug.) for five years (2011~2015), and missingvalues were imputed using multiple imputation methods. Of the 15,848 individuals collected, approximately 47% and 52.9%were collected using the AeCN and LT methods, respectively. A high incidence of migratory SBPHs was observed duringJulian days 144-166 using the AeCN method. Generally, the migratory SBPHs from China composed 39.4% of the totalpopulations of SBPHs. These results would provide valuable information to predict the incidence period of migratory SBPHsand establish a proactive management system against SBPH.

The small brown planthopper (SBPH), Laodelphax striatellus, is one of the most serious pest insects of rice plants.Buprofezin has been used to control SBPH for more than a decade, however, the occurrence of buprofezin resistant SBPHwas reported recently. To develop an alternative pest control an alternative pest control strategy, RNA-seq of buprofezin-treatedSBPH was performed to screen the insecticidal target genes for RNA interference (RNAi). Six genes were selected fordsRNA synthesis, and applied to SBPH to assess the insecticidal efficacy. Two and three of those dsRNAs showed moderatedand substantial insecticidal activity up to 60% of mortality in one week, respectively. These results demonstrated the potentialof gene screening strategy for the development of RNAi-based pest management program.

The small brown planthopper (SBPH), Laodelphax striatellus, which transmits rice stripe virus (RSV) is one of thenotorious pests of rice plants. To investigate the factors of vector insect responding to virus introduction, the total RNAof RSV-viruliferous SBPHs was subjected to RNA-Seq to analyze the SBPH-RSV interactome. Based on the transcriptomicchanges of RSV carrying SBPHs, eight cDNA sequences possibly related to RSV replication in SBPH were selected,and dsRNAs targeting those sequences were synthesized and applied to SBPH. Three of those dsRNAs showed over 90%of substantial RSV suppression efficiency in SBPH, that demonstrated a potential of RNAi-based virus-vector managementprogram.

Locomotion can be investigated using visual locomotion scoring or computer-assisted techniques such as force plates or pressure plates. Although visual locomotion scoring is inexpensive, it is subjective and depends on observers. Conversely, computer-assisted techniques are objective and more sensitive than visual assessment. Many studies of gait in large breed dogs have been conducted using these techniques; however, there have been few investigations of small to toy breed dogs. Therefore, the purpose of the present study is to conduct gait analysis in small to toy breed dogs and to suggest normal reference ranges for clinical application. Twenty healthy dogs with no lameness or orthopedic pain weighing from 2 kg to 12 kg were used. The dogs were divided into two groups according to their weight, after which gait analysis was conducted using a pressure plate. The pressure force ratio between the forelimb and hindlimb was significantly lower in group 2 (mean 4.2 kg) than group 1 (mean 10.4 kg), while the stance time ratio between the forelimb and hindlimb tended to increase in group 2, but there was no significant difference. Other numerical values in group 2 tended to decrease, with some significant differences being observed. Overall, the results suggest that there are different gait features in small to toy breed dogs when compared with middle and large breed dogs.

목 적 : 유방 MRI검사에서 회전 자장(B1)의 불균일성은 코일의 중심에 검사부위가 없고 우측과 좌측으로 나뉘어진 유방의 해부학적 구조의 영향을 많이 받는다. 또한 환자의 유방과 유방사이, 유방과 코일사이의 air-gap이 증가할수록 B1의 불균 일성도 증가하여 영상의 화질을 저하시킨다. 그러나 최근 유방암 환자의 증가에 따라 비대칭유방 환자 및 편측유방 등 small breast 환자들이 증가하고 있다. 이에 본 연구는 자체 제작한 phantom과 다양한 B1 calibration scan parameter를 이용하여 small breast에서 B1 calibration scan parameter의 변화에 대한 평가와 영상화질에 미치는 영향을 알아보고자 하였다. 대상 및 방법 : 검사 대상으로는 Invivo사의 breast phantom과 자체 제작 phantom을 이용하였다. 장비 사에서 권고하는 B1 calibration parameter가 최적의 조건을 나타내는지 평가하기 위한 대상으로 breast coil을 가득 채우는 Invivo사의 breast phantom을 사용하였고, 자체 제작 phantom을 이용하여 small breast일 때 최적의 B1 calibration parameter를 확인하였다. 연구에 사용된 장비는 Philips INGENIA 3.0T(Philips medical system, Netherlands)이고, 신호수집 코일은 16channel Breast coil을 사용하였다. 연구방법은 B1 calibration scan parameter 중 slice thickness(두께)를 5, 8, 12, 15, 20 mm로 Flip angle(FA)을 20, 40, 60, 80, 100 degree로 변화시켜가며 B1 map과 e-THRIVE 영상을 획득하였다. 정량적 평가로 획 득한 영상의 우측(Rt)과 좌측(Lt)에 각각 5개의 ROI를 그려 신호 대 잡음비(signal to noise ratio; SNR)를 비교 분석하였고 one-way ANOVA(SPSS 18.0K for windows)로 통계 검정하였다. 정성적 평가방법으로는 B1 map profile을 통해 B1의 균일성을 비교하였다. 결 과 : Invivo phantom으로 획득한 B1 map과 e-THRIVE 영상의 SNR은 B1 calibration scan parameter의 두께와 FA의 변화에 따라 차이가 있었다(P<0.001). 두께별 변화에서는 8 mm, FA별 변화에서는 60°일 때 가장 높게 나타났다. 자체 제작 phantom에서도 B1 map과 e-THRIVE 영상의 SNR은 B1 calibration scan parameter의 두께와 FA의 변화에 따라 차이가 있었다(P<0.001). 두 영상 모두 두께가 12mm 일 때 가장 높게 나타났으며, FA은 80°일 때 가장 높게 나타났다. B1 profile을 통해 확인한 자체 제작 phantom의 B1 균일도는 두께가 12 mm, FA이 80°일 때 가장 균등한 그래프를 나타냈다. 결 론 : 자체 제작 phantom의 B1 map 분석을 통해 장비사에서 권고된 parameter 변화의 필요성을 제고하고, 최적의 B1 calibration scan parameter를 확인할 수 있었다. 따라서 small breast 환자의 경우에는 B1 calibration scan parameter의 변 경이 필요하며, 이를 통해 SNR과 B1 균일성이 향상된 진단적 가치가 높은 유방 MRI영상을 얻을 수 있을 것이라 사료된다.

Competitiveness of small and medium companies often rely on the competency of their employees. Many employees however try to move to better environments if possible, which results in high uncertainty in maintaining solid human resources. The purpose of this paper is to investigate the influencing factors of turnover intention and organizational loyalty of the early experienced, especially three to five years experienced, employees in the small and medium enterprises. A survey had been conducted using both LMX (Leader Member eXchange) and TMX (Team Member eXchange) as an effort to test the impact of strategic human resource management factors on turnover intension and organizational loyalty. It has been observed that the level of LMX is critical on the turnover intension, while the levels of LMX and TMX are positively related to the organizational loyalty. Especially significant mediation effect affects on the organizational loyalty for TMX via LMX in the serial structure. The human resource management factors become effective under the circumstances where leader and team members exchange activities are activated. These findings can be used in reducing turnover intention and increasing organizational loyalty of early experienced employees by enhancing the leadership training of middle level managers of the small and medium enterprises organizations. Besides, a set of active communication channels should be provided for the young employees so that they can share their work experiences and difficulties within the organization. The key results of this study may help the practitioners set up a management plan to maintain a low turnover rate for their organizations.

After being subjected to different cooking methods, small black beans (Rhynchosia nulubilis) were investigated in order to assess the effects of the retained bioactive compounds. Using uncooked, pan broiled, boiled, steamed, and pressure cooked beans, the inhibitory effects of MCF-7 cell migration were evaluated at protein concentrations of 40, 160, and 640 μm/mL, using the Boyden's chamber assay. All protein concentrations (40, 160, and 640 μm/mL) of pan broiled beans showed significant reduction (59.83, 32.48, and 21.37%, respectively) in the rate of cell migration to the lower chambers (p-value less than 0.001). Estimated cell migration rates correlated to the exponential decay between experimentally measured cell migration rates and converted samples. The range of estimated cell migration rate for each 100 mg/mL of cooked sample was as follows: pan broiled (21.16%), boiled (22.48%), steamed (22.48%), pressure cooked (29.52%), and uncooked (35.03%) beans. Our study indicated that selective modifications of cooking methods for small black beans, such as pan broiling, ameliorated the inhibitory effects of MCF-7 cell migration. This suggests that optimized cooking methods increase the nutritional contents of the cooked food.

Over the last decades, the global luxury business has become dominated by large conglomerates. Backed by the financial power of their parent companies, formerly small and often family-owned brands have expanded their presence around the globe. They have established themselves in some of the most expensive shopping districts, acquired illustrious testimonials, and sponsored prestigious events. Almost overwhelmed by the omnipresence of luxury, consumers are said to have begun looking for the “genuine” and “unique,” favoring smaller, less homogenized and more intimate luxury brands not necessarily known to the larger public. This study thus looks beyond the well-known players in the luxury market and explores the differentiating strategies used by independent niche luxury companies. It aims to identify factors contributing to their success in a global market otherwise dominated by ever-growing luxury giants.

This paper aims to expand our understanding on the success factors of small businesses, which comprise of more than 90 percent of all businesses in U.S. in 2016. One of the most critical issues behind small business success is the competition, which becomes increasingly intense. Not only small businesses fiercely compete with larger competitors (e.g. Emergence of mega-retailers such as Wal-Mart has intensified the competition in the grocery industry, and, as a result, many mom and pop stores have gone out of business.), but also the competition against each other (i.e. competition between small businesses) becomes increasingly aggressive. Yet, the current literature in marketing have less investigated the issue of competition between small businesses, while issues on competition between small and large businesses have been somewhat explored. Another phenomenon in small business that has not received much attention is the competition between generalist and specialist firms. This phenomenon of specialist versus generalist competition is in fact frequently observed in many industries. Therefore, we study competition between small businesses, focusing on the competition between generalist and specialist small businesses. We examine how competitive intensity, as well as market environmental factors, affect the performance of small businesses. Specifically, we decompose the competitive intensity into two types, one between generalists and the other between specialists, in order to identify the differential effects of competition between generalist and specialist, and examine their impacts on the generalist and specialist performance. Given the research questions above, we develop the following hypotheses based on the past research in marketing. First, we expect competition has a positive effect on generalist performance, while we expect the opposite effect on specialist performance. We also expect that the effect of competition becomes weaker, as the competition becomes more intense. That is, the positive (negative) impact of competition on generalist (specialist) performance becomes less significant as there are more competitors in the market. We further expect that competition between the same type of businesses (e.g. between generalists) has a positive effect on their performance, while competition between the difference types (e.g. between generalist and specialist) has a negative effect on their performance. Moreover, we expect that market environmental factors have differential effects on the performance of generalist and specialist. To test the aforementioned hypotheses on the small business competition between generalist and specialist, we collected data from the health care industry on private physician practices (offices) in Korea. Out data contain, for each practice, monthly sales, number of doctors, number of nurses, type of practice, number of beds and zip code it is located in. We also have data on average consumer spending, average medical spending, percentage of patients over sixty years old for each zip code. Moreover, we have data on competition between the same type of offices (e.g. between generalists and between specialists) and competition between different types (e.g. between generalist and specialist). Note that our data collected from the Korean health care industry fit our research questions well. First, the majority of medical service providers in Korea are small private practices with an average number of two doctors, and the share of generalist and specialist practices are about half-and-half. Second, unlike the U.S. health care industry, generalist physicians in Korea usually practice a number of different fields, while specialist physicians focus on their own specialties. Third, patients in Korea do not usually distinguish between generalist and specialist offices, and they do not usually have a primary care physician. As a result, patients can easily switch between physicians, and in fact the switching is highly likely, as all medical information is centralized by government. Our main findings are as follows. First, we find that competition has a positive effect on generalist performance, while it has a negative effect on specialist performance. Specifically, we find that generalist benefits from competition with both generalist and specialist, while specialist suffers from the competition with both specialist and generalist. As competition becomes intense, meaning the number of physician offices increases, it would attract more patients to visit the area where physician offices are clustered (clustering effect), while it becomes easier for patients to switch from one to the other nearby offices. In particular, as generalist usually treats multiple fields (specialties), generalist tends to benefit from the patients who switch from specialist. In other words, generalists benefit from competition, as they free ride on clustering of physicians including specialists, while specialists would suffer from competition. Second, our findings show that as the competition becomes more intense, its effect on business performance becomes weaker. That is, a high level of competition weakens the benefits and damages imposed on the performance of generalist and specialist, respectively. When there are more physician offices to switch, the effect of free riding becomes weaker, as patients have more options to choose from. Thus, the benefit of generalist from free riding becomes weaker, as well as the negative effect on specialist performance. Moreover, our findings suggest that market environmental factors do influence the business performance. Specifically, the performance of both generalist and specialist improves as the number of doctors increases. However, an increase in the number of nurses has a different effect on generalist and specialist. Employing a larger group of nurses has a negative effect on generalist because it might cause the operation of the office to be less efficient. However, since specialist’s practice usually involves a more technical and sophisticated processes, a larger group of nurses could make the office more efficient having a positive impact on the sales performance. Similarly, we find the effects of other environmental factors have differential impacts on the performance of specialist versus generalist.

This research investigates the power use in self and collective interests of retailers and small apparel suppliers’ relationships. Our findings highlighted that power use of fast fashion retailers in self-interest and collective interest related goals are evident mainly in the areas of capability development, production processes and innovation in asymmetric relationships with Turkish apparel suppliers.

This preliminary qualitative research investigates how stylistic innovation affects sales performance of small arts and crafts firms in business-to-business and business-to-consumer markets in Taiwan. Specifically this research examines entrepreneurial cognitive complexity, which is the cognitive structure of an entrepreneur on his or her social world, and its interplay with stylistic innovation, particularly the changes of design in appearance or symbolic meaning of products, and strategic decisions of five Taiwanese small arts and crafts firms. Applying cognitive mapping to determine the cognitive contents, structures and also their relations of the entrepreneurs in making decision related to stylistic innovation, this research examines how owners of small Taiwanese arts and crafts firms specifically seek, interpret and internalize information and knowledge on style and design in the new product development and innovation processes. Research results show that the domain specific cognitive complexity of the entrepreneur influences the selection of relevant and appropriate dimensions in stylistic innovation. Entrepreneurs’ strategic decision to target at the business-to-consumer (customer-oriented or designer-driven) or business-to-business (mainly designer-driven) markets and also the buyer-seller relationship will affect the seeking, interpretation and internalization of information and knowledge in the process of stylistic innovation. Respondents targeting at business-to-business markets tend to have a higher level of cognitive complexity, compared with those targeting at business-to-consumer markets. Research results tend to suggest that the higher level of cognitive complexity, the greater the sales turnover. Future research should determine the relationship between cognitive complexity and marketing performance.

The sewage and wastewater (SAW) are a well-known major source of eutrophication and greentide in freshwaters and also a potential source of thermal pollution; however, there were few approaches to thermal effluent of SAW in Korea. This study was performed to understand the behavioral dynamics of the thermal effluents and their effects on the water quality of the connected streams during winter season, considering domestic sewage, industrial wastewater and hot spring wastewater from December 2015 to February 2016. Sampling stations were selected the upstream, the outlet of SAW, and the downstream in each connected stream, and the water temperature change was monitored toward the downstream from the discharging point of SAW. The temperature effect and its range of SAW on the stream were dependent not only on the effluent temperature and quantity but also on the local air temperature, water temperature and stream discharge. The SAW effects on the stream water temperature were observed with temperature increase by 2.1~5.8℃ in the range of 1.0 to 5.5 km downstream. Temperature effect was the greatest in the hot spring wastewater despite of small amount of effluent. The SAW was not only related to temperature but also to the increase of organic matter and nutrients in the connected stream. The industrial wastewater effluent was discharged with high concentration of nitrogen, while the hot spring wastewater was high in both phosphorus and nitrogen. The difference between these cases was due to with and without chemical T-P treatment in the industrial and the hot spring wastewater, respectively. The chlorophyll-a content of the attached algae was high at the outlet of SAW and the downstream reach, mostly in eutrophic level. These ecological results were presumably due to the high water temperature and phosphorus concentration in the stream brought by the thermal effluents of SAW. These results suggest that high temperature of the SAW needs to be emphasized when evaluating its effects on the stream water quality (water temperature, fertility) through a systematized spatial and temporal investigation.

Thermal effluent of the hot spring has long been a field of interest in the relationship between temperature gradient and freshwater algae in geology, limnology and aquatic ecology throughout the world. On the other hand, many artificial hot springs have been developed in Korea, but the research on them has not been still active. This study was performed every month from December 2015 to September 2016, to elucidate the spatiotemporal effects of thermal wastewater effluent (TWE) on the ecosystem of benthic algal assemblage in four stations (BSU (upstream), HSW (hot spring wastewater outlet), BSD1~2 (downstream)) of the upstream reach of the Buso Stream, a tributary located in the Hantan River basin. During the survey, the influencing distance of temperature on TWE was <1.0 km, and it was the main source of N·P nutrients at the same time. The effects of TWE were dominant at low temperature and dry season (December~March), but it was weak at high temperature and wet season (July~September), reflecting some seasonal characteristics. Under these circumstances, the attached algal communities were identified to 59 genera and 143 species. Of these, the major phylum included 21 genera 83 species of diatoms (58.0%), 9 genera 21 species of blue-green algae (14.7%) and 25 genera 32 species of green algae (22.4%), respectively. The spatiotemporal distribution of them was closely related to water temperature (5℃ and 15℃) and current (0.2 m s-1 and 0.8 m s-1). In the basic environment maintaining a high water temperature throughout the year round, the flora favoring high affinity to PO4 in the water body or preferring stream habitat of abundant NO3-PO4 was dominant. As a result, when compared with the outcomes of previous algal ecology studies conducted in Korea, the Buso Stream was evaluated as a serious polluted state due to persistent excess nutrient supply and high thermal pollution throughout the year round by TWE. It can be regarded as a dynamic ecosystem in which homogeneity (Summer~Autumn) and heterogeneity (Winter~Spring) are repeated between upstream and downstream.

The purpose of this study is to review the relationship between managerial system and incremental innovation, and the mediating effect of knowledge transfer in small business. In order to verify and achieve the purposes mentioned above, questionnaire data were gathered and analysed from 255 enterprise managers in western Kangwon-do province. Empirical survey's findings are as follows; First, CEO's support and education/training appeared to be positively related with knowledge transfer. Second, managerial system and knowledge transfer appeared to be positively related with incremental innovation. Third, knowledge transfer had mediating effect on the relationships of CEO's support-incremental innovation and education/training-incremental innovation.

Diversification to develop oak pruned neck utilization technology reduction of operation cost of cheonma( Gastrodia elata) farmers is the purpose of this research, but the results of the experiment are as follows. The soil chemistry of the plantation was very weak in 2015 when the pH was 5.7, weakly acidic and EC was 0.41 (ds/m), but the faux spring area was very sunny, but at the end of May, early June, late July And so on were at a maximum temperature of 25oC or more, and underground temperature fell below freezing in late January 2016. In the content of the survey of the harvested volume, treatment with a diameter of 6 to 10 cm appeared in 1,366 g total weight and in treated plots with a diameter of 20 cm or more, appeared in 1,542 g, confirming that the number and weight of the interspaces from the small neck is higher than the practice.

본 연구는 현대교회의 전도 패러다임 중에 소그룹 중심의 전도 전략과 방법을 주로 다루고 있다. 믿지 않는 사람들과 연결 할 수 있는 다리 역할을 하는 것이 전도소그룹이다. 본 연구에서는 소그룹 중심의 전도에 대한 기본적인 개념과 이해를 제시하였고, 또한 초대교 회에서 소그룹의 중요한 원리를 발견하였다. 또한 소그룹 중심의 전도 형성과정이 무엇인지를 밝히었고, 구체적인 실천 방안으로 전도소그룹 의 내용을 소개하였으며, 미국의 뉴호프커뮤니티교회(New Hope Community Church) 대전 제자들교회의 전도소그룹을 소개하고 분석함으로써 효과적인 전도소그룹의 전도방법과 전략에 대하여 설명 하였다. 전도소그룹에서는 훈련된 평신도 지도자와 구성원들이 함께 소그룹 안에서 구도자를 위해 어떻게 초대하고 전도해야 할지 논의하 고, 기도하며 예배하는 모임이 되어야 한다. 한국교회는 현재 전도소그 룹으로 전도패러다임의 전환이 요청되고 있다. 교회 전도사역의 우선순 위를 전도 소그룹에 두고, 평신도들을 훈련하여 전도를 생활화 할 때, 한국교회는 건강한 사도적 교회로 성장해 나갈 것이다.

Although assisted reproductive technology (ART) has been developed in many mammalian species including cows, the only embryo preservation technology that is available is cryopreservation. In the present study, small molecules were used to preserve embryos at room temperature. The basic medium for embryo preservation consisted of 1% BSA non-cryopreservation medium (BNC) instead of fetal bovine serum (FBS). To maintain survival and prevent damage during embryo storage, three candidate small molecules were selected—CHIR99021, Y-27632 and Thiazovivin—and their concentrations were optimized. Then, the embryos in the small molecule supplemented preservation medium were stored at room temperature. The viability and hatching rate of embryos stored at 10°C were greater for Y-27632-BNC and CHIR99021+Y-27632-BNC compared to BNC. However, the rate was lower for Thiazovivin-BNC compared to BNC. Although there were no surviving embryos after storage at 20°C, the viability and hatching rate of embryos significantly increased in Y-27632-BNC and CHIR99021+Y-27632-BNC compared to BNC. The mechanism by which small molecules enhance survival of embryos during storage was investigated, and expression of heat shock protein 70 was observed to increase. The findings of this work may be useful in improving ART in the agricultural field.

Through density functional theory calculations, to provide insight into the origins of the catalytic activity of Au nanoparticles (NPs) toward oxidation reactions, we have scrutinized the oxygen adsorption chemistry of 9 types of small unsupported Au NPs of around 1 nm in size (Au13, Au19, Au20, Au25, Au38, and Au55) looking at several factors (size, shape, and coordination number). We found that these NPs, except for the icosahedral Au13, do not strongly bind to O2 molecules. Energetically most feasible O2 adsorption that potentially provides high CO oxidation activity is observed in the icosahedral Au13, our smallest Au NP. In spite of the chemical inertness of bulk Au, the structural fluxionality of such very small Au NP enables strong O2 adsorption. Our results can support recent experimental findings that the exceptional catalytic activity of Au NPs comes from very small Au species consisting of around 10 atoms each.