This study was conducted to investigate the effectiveness of a nutrition and exercise education program on weight control and nutrition knowledge. The nutrition-exercise educational period was 12 weeks. The subjects were 160 adult women with an average age of 48.1 years. We investigated general characteristics, diet history, eating habits, and intake frequencies of six food groups by survey. A total of 94 women among the subjects participated in the pre and post nutrition knowledge evaluations and anthropometric data assessment. After the program, body weight, body mass index (BMI), and waist circumference significantly decreased. Further, % of body fat decreased, but not significantly. BMI significantly decreased (p<0.001) from 25.14 to 24.80 kg/m2, and waist circumference significantly decreased (p<0.001) from 79.72 to 77.63 cm. The nutrition knowledge scores of subjects significantly increased (p<0.001) from 8.01 to 9.03. However, there was little change in employment. These results suggest that the nutrition-exercise education program may improve obesity index and nutrition knowledge. However, it is necessary to develop a specialized weight control program for workers.

The objective of this study was to investigate the interrelationship of weight and hormonal changes through the administration of vitamin A to first time pregnant heifers. A total of 28 Korean heifers was used for this study. The heifers were divided into two groups - with vitamin A (n=14) and without vitamin A (control) (n=14) in the feed. Body weight increased in vitamin A treated heifers starting 9 months until 15 months. After pregnancy, vitamin A treated heifers were found to maintain higher body weights than the control group. Pre-pregnancy and post pregnancy progesterone levels were not different between the two groups. Serum estradiol levels of heifers at different growth stages showed relatively higher E2 levels than the control. Also, the control during pregnancy may show higher serum E2 levels than the vitamin A treated heifers. The growth phase serum estradiol levels in heifers may be relatively higher than the control. During pregnancy it showed a similar trend. Serum levels of vitamin A treated heifers did not differ from pregnant heifers at 5 months of age. However, after 5 months from conception until 8 months of treatment it showed a high level. Serum cholesterol in pregnant cows was higher in the control group than the treatment from beginning until the end of pregnancy. This is considered to be related to fetus development during pregnancy, as well as the mother's health.

The purpose of this study was to determine the therapeutic effect of slope changes of the treadmill with body weight-supported training on gait characteristics in patients with hemiplegia. The volunteered subjects were divided into 3 groups based upon slope changes: control group (0° incline), 7° group (7° incline), 12° group (12° incline), They were trained the body weight-supported treadmill training (BWSTT) for 8 weeks. All subjects were supported up to 40% of their body weight on the treadmill training and the support was gradually decreased to 0~10% as the subjects were adapted to the training. There were significant improvements of walking velocity, step length of the affected side, the asymmetry ratio of step length in 7° group (57.80 cm/s, 67.25 cm, .14), 12° group (71.00 cm/s, 71.00 cm, .11) than control group (40.62 cm/s, 55.00 cm, .74) (p<.05): there were no differences between group 7° and 12° group in the all outcomes (p>.05). Both 7° group and 12° group scored higher than the control group in those outcomes and finally the effects of slopes changes of the treadmill were effective on gait characteristics of patients. But it s till remains undetermined what degree on the treadmill might be better to train the hemipareric patients. Therefore, more studies are required to look into minutely the changes of slopes of the treadmill influencing on gait characteristics.

Di-n-butyl phthalate (DBP), diisononyl phthalate (DINP) and di-(2-ethylhexyl) adipate (DEHA) are ubiquitously distributed chemicals that are widely used as plasticizers and also found at low levels in foods. The aims of this study were to determine whether perinatal exposure to DBP, DINP and DEHA could alter normal patterns of neonatal development. Dams were provided with pulverized soy-free diet containing 20, 200, 2,000 and 10,000 ppm of DBP, 40, 400, 4,000 and 20,000 ppm of DINP, or 480, 2,400 and 12,000 ppm of DEHA from gestational day 15 to postnatal day 21. Exposure to the high doses of DBP, DINP and DEHA during gestational period significantly decreased food consumption and body weight gain of dams. These chemicals reduced neonatal body weight as well as that of the after maturation. Also, exposure to DINP of all the doses used and the higher doses (2,400 and 12,000 ppm) of DEHA decreased AGD at PND 1 in male neonates, though that to DBP did not affect AGD in males. In female neonates, an increase in AGD was observed in DBP- and DINP-exposed animals at the highest doses. Moreover, these chemicals affected survival rate of pups at PND 5, and delayed onset of eye opening in all chemical-exposed groups at PND 17. These results suggest that perinatal exposure to these chemicals may affect the normal development and / or growth of offspring.

The purpose of this study was to investigate the changes of food habits and anxiety level of obese children on body weight control program. The body weight control program included nutrition education, psychotherapy and exercise for weekly session during 9 months. The results from this study were as follows. A total of 27 obese children(boys 44.4%, girls 55.6%) participated in this study. The average age of children was 11.7 years, average height and weight were 141.7cm and 48.1kg respectively. Rohrer index(RI) of children was significantly decreased from 167 to 163(p〈0.001) and BMI was significantly decreased from 24.5 to 23.9 (p〈0.01) after body weight control program. This study also found obesity index(OI) was significantly decreased from 133% to 128%(p〈0.01) of 18 children after program. There was not significant difference in food habits score but frequency of overeating, and eating frequency of meats were significantly decreased(p〈0.05) after body weight control program. Also depression score significantly decreased after body weight control program(p〈0.001) and there was significant negative correlation(r=-0.552) between food habits and anxiety level. The factors analysis of anxiety items indicated that children had feelings more calm and sate after program(p〈0.05). Therefore continuous and practical nutritional education and psychotherapy to change food habits and anxiety level are necessary to decrease child obesity. These results suggest that body weight control program including nutrition education, exercise and psychotherapy may be effective physiological and psychological body health of obese children.

The purpose of this study was to investigate the changes of obesity and depression level of obese children on body weight control program. The body weight control program included nutrition education, psychotherapy and exercise for weekly session during 9 months. The results from this study were as follows. A total of 27 obese children participated in this study. The average age of children was 11.7 years, 70% of children had regular exercise. Average exercise time was 1.2 hours and watching television time was 1.8 hours. Children's serum composition were within normal ranges. Rohrer index(RI) was significantly decreased to 163 from 167(p<0.001) and BMI was significantly decreased to 23.9 from 24.5(p<0.01) after body weight control program. There was not significant difference in depression score after body weight control program and there was not significant correlation between obesity and depression level. The response tendency of depression items indicated obese children had negative depression feelings and couldn't have hopeful mind to the future. But there were significant increase(p<0.05) in depression and hopeful mind in factor analysis. The suggestion and limitations of this study were discussed. These results suggest that body weight control program including nutrition education, exercise and psychotherapy may be effective for helping obese children.

발효에 의한 헛개열매의 기능성 상승 정도를 검토하고자, 헛개열매열수추출물을 발효시킨 후 급성 및 만성 알코올 투여 간손상 동물모델을 통하여 체중감량 억제, 알코올 분해 및 간기능 개선 효능을 검증하였다. 급성 알코올 투여 동물모델에서 헛개열매발효군(ET-FHWE)은 알코올대조군(ET)에 비하여 혈청 알코올 농도가 유의적으로 감소되었고, 특히 알코올 투여 3시간 후의 알코올 농도는 헛개열매추출액발효물에 의해 46.1%, 헛개열매열수추출물에 의해 19.1% 감소된 것으로 나타났다. 또한 알코올 투여에 의해 증가된 혈청 아세트알데하이드 농도는 헛개열매추출액발효물에 의해 알코올 투여 3시간 후에는 48.7%, 5시간 후에는 39%로 알코올대조군(ET)보다 유의적으로 감소하였고, 이는 헛개열매열수추출물은 발효에 의해 알코올 및 아세트알데하이드 분해능이 증가하는 것으로 사료되었다. 만성 알코올 투여 간손상 동물모델 실험에서 알코올 투여에 의해 상승된 혈청 알코올 농도는 헛개열매열수추출물과 헛개열매추출액발효물 투여에 의해 각각 31%, 41% 유의적으로 감소하였다. 혈청 아세트알데하이드 농도와 γ-GTP 활성도는 헛개열매열수추출물과 헛개열매추출액발효물 투여에 의해 알코올대조군(ET)보다 유의적으로 감소되었으며, 장기간 알코올 투여에 의한 체중 감소 억제 및 간조직 지질수준의 유의적 감소를 나타내었다. 또한 헛개열매추출액발효물은 장기간의 알코올 투여로 인해 감소된 혈당을 유의적으로 증가시키는 것으로 나타났다. 본 연구 결과, 급성 알코올 투여 동물모델에서 헛개열매열수추출물은 발효에 의해 알코올 및 아세트알데하이드 분해능이 증진되었고, 만성알코올 투여 모델을 통한 실험에서는 발효에 의해 헛개열매의 간기능 개선효능이 유지됨과 동시에 일부 효능(혈청 지질 및 혈당 수준 개선능)은 증가하는 것으로 나타났다. 따라서 헛개열매추출액발효물은 급성 및 만성 알코올성 간손상 억제에 있어서 헛개열매열수추출물보다 더욱 강력한 기능성 물질로 활용될 수 있을 것으로 기대된다.