Health concerns related to particulate matter (PM) pollution are on the rise globally. This study investigates the effects of the main components of PM on human airway epithelial cells (Calu-3), focusing on three distinct types: PM10-bound PAHs (including Benzo[a]anthracene and Benzo[b]fluoranthene), PM10-bound trace elements (containing arsenic and lead), and PM2.5-bound ions (comprising sodium and calcium). Calu-3 cells were exposed to these PM components at concentrations ranging from 2 to 100 μg/mL. Unexposed Calu-3 cells exhibited a 60% increase in metabolic activity after 12 hours. In contrast, exposure to PM components resulted in significant reductions in cell viability, with PM10-bound PAHs and PM10-bound trace elements causing decreases of 54% and 55% respectively, and PM2.5-bound ions leading to a 63% reduction at 100 μg/mL. Additionally, there was found to be a notable rise in the expression of proinflammatory cytokines IL-8 and TNF-α. Specifically, IL-8 levels increased by 456%, and TNF-α levels rose by 660% after 12 hours of exposure to PM2.5-bound ions. These findings indicate that the size and composition of fine dust particles play a critical role in their cytotoxic effects, contributing to increased cell death, membrane damage, and necrosis in airway epithelial cells.

The purpose of this study is to compare and analyze the impact range of explosion damage due to gas leaks at LPG filling stations, focusing on propane and butane, which are components of vehicle LPG. The scenarios were designed based on the explosion incident at an LPG filling station in Gangwon-do, where an actual gas leak accident occurred, resulting in Scenario I and Scenario II. The ALOHA program, developed by the U.S. National Oceanic and Atmospheric Administration (NOAA), was used as the tool to analyze the impact range of the explosion damage for both substances. The results of the study indicated that, under identical conditions, propane had a wider impact range of damage than butane. This is presumed to be due to the greater explosion energy of propane, attributable to its physicochemical properties. Therefore, when preparing for LPG leak accidents, measures for propane need to be prioritized. As safety measures for propane, two suggestions were made to minimize human casualties. First, from a preventive perspective, it is suggested to educate workers about propane. Second, from the perspective of response measures and damage minimization, it is suggested to thoroughly prepare emergency evacuation and rescue plans, evacuation routes, designated shelters, and emergency response teams. This study compares and analyzes the impact range of radiative heat damage based on LPG components. However, hazardous accidents are critically influenced by the type of leaking substance, the form of the leak, and meteorological factors affecting the diffusion pattern of the substance. Therefore, for future research, it is proposed to model various leakage scenarios for the same substance to conduct a comprehensive risk assessment.

Rehmannia glutinosa root and Saururus chinensis plant have been widely used in natural traditional medicines. This study was conducted to investigate the effect of the content of the main components of R. glutinosa root and S. chinensis plant by extraction method. The results of comparative analysis of extraction yield, total flavonoid, and polyphenol content by extraction method indicated that extraction yield had the best performance with hot water extraction for R. glutinosa and ultrasound-assisted extraction for S. chinensis. The total flavonoid and polyphenol content had the best performance with maceration extraction for R. glutinosa and ultrasound-assisted extraction for S. chinensis. ABTS and DPPH activity was excellent with maceration extraction for both R. glutinosa and S. chinensis. The analysis of the main components showed that maceration extraction was most effective for both S. chinensis and R. glutinosa. Specifically, maceration extraction of R. glutinosa yielded 1.5 times more than conventional ultrasound-assisted extraction.

본 연구는 국내 천연 자생 식물인 쥐오줌풀을 정유 추출하여 향기 성분 분석결과를 기반으로 항산화(DPPH, ABTS), 세포생존율(MTS), 항염(Nitric oxide)실험을 수행하였다. 향기성분 분석결과 쥐오 줌풀의 대표 유효 성분인 ester류의 bornyl acetate가 47.88%로 타지역에 비해 높은 함유량을 나타났으며 patchouli alcohol (18.9%), camphene (11.37%), camphene (11.37%), α-Pinene (5.44%), D-limonene (1.11%)등이 동정되었다. 항산화 활성인 DPPH 라디칼 소거능이 250 μl/ml에서 73.62%, ABTS 라디칼 소거능이 250 μl/ml에서 82.17%을 보였으며, 세포독성이 확인되지 않은 5 μl/ml의 농도에서 NO 생성 저해능은 대조군에 대비 62.02%로 감소함을 나타났다. 이를 통해 기능성 제품으로의 활용 가능성을 과학 적으로 검증하여 쥐오줌풀 정유를 활용한 연구분야에 일부 기여할 수 있을 것이라 기대되는 바이다.

In this study, the design of fuel tank for SUVs (sports utility vehicles) was addressed through structural FE-simulation. For safety evaluation, we performed a shape analysis of fuel tank, discovered improvement measures for weak areas, and reflected them in the fuel tank design. Additionally, a strength analysis was conducted and the analysis results were reflected in the design. As a result of analysis through various design changes, it was possible to propose an appropriate fuel tank shape. Additionally, the effect of changes in the shape of the reinforcement and mounting bracket on the stiffness and strength of the fuel tank bracket was investigated.

In this study, the design of parking brake mounting bracket for SUVs (sports utility vehicles) was handled through structural analysis. For safety evaluation, we conducted a shape analysis of parking brake mounting bracket, discovered improvement measures for weak areas, and reflected them in the design. In addition, a strength analysis was performed and the analysis results were reflected in the design. As a result of analysis through various design changes, it was possible to suggest an appropriate parking brake mounting bracket shape. In addition, the effect of changes in the shape of the reinforcement and mounting bracket on the stiffness and strength of the parking brake mounting bracket was investigated.

Earthquakes of magnitude 3.0 or greater occur in Korea about 10 times on average yearly, and the number of earthquakes occurring in Korea is increasing. As many earthquakes have recently occurred, interest in the safety of nuclear power plants has increased. Nuclear power plants are equipped with many cabinet-type control facilities to regulate safety facilities, and function maintenance is required during an earthquake. The seismic performance of the cabinet is divided into structural and functional performances. Structural performance can be secured during the design procedure. Functional performance depends on the vibration performance of the component. Therefore, it is necessary to confirm the seismic performance of the components. Generally, seismic performance is confirmed through seismic simulation tests. When checking seismic performance through seismic simulation tests, it is difficult to determine the effect of frequency and maximum acceleration on an element. In this paper, shaking table tests were performed using various frequencies and various maximum accelerations. The seismic performance characteristics of the functions of electrical equipment components were confirmed through tests.

In this study, the shape evaluation and design of the spare tire carrier for SUV (sports utility vehicle) were addressed through structural analysis. Spare Tire Carrier analysis was conducted to evaluate rigidity, and strength and improvement measures for appropriate shapes were found and reflected in the design. Through structural analysis of the spare tire carrier, this study was conducted to derive an optimal design plan as the stiffness and strength needed to be increased for stable installation of the spare tire carrier. Compared to the existing model, the bar, which was curved, was changed to a straight line to shorten the length, thereby increasing rigidity. In addition, because the moment was concentrated in the structure of the rear hanger mounting bracket, the side part of the bracket was extended, but the cross member stiffness was relatively weak, so it did not have a significant effect.

In this study, the shape evaluation and design of clamp mount for SUVs (sports utility vehicles) was dealt with through structural analysis. The clamp mount analysis was performed to evaluate stiffness, strength and improvement plans for appropriate shape were found and reflected in the design. In addition, strength analysis and was performed in parallel to solve the problem of rib design around the edge part of the clamp mount and the thickness effect results were reflected in the design. As a result of analysis through various design changes, it was possible to present an appropriate reinforcement design shape. In addition, when the thickness of the fuel tank was changed from 3.2mm to 4.0mm, the stiffness of the fuel tank decreased by approximately 30%, and reinforcement was required.

본 논문에서는 모바일 RPG 장르의 튜토리얼의 구성요소를 분석하고, 이를 바탕으로 모바일 RPG 튜토리얼 제작시 고려해야 하는 요소들에 관해 고찰하였다. 이를 위하여 먼저, 모바일 게 임의 UI 속성을 살펴보고, 게임 요소에 대한 선행연구를 통해 RPG 구성요소를 확인하였다. 다 음으로 이를 바탕으로 모바일 게임 <리니지M>과 <리니지2M>, <리니지2 레볼루션>, <검은사 막 모바일>과 PC 게임 <로스트아크>, <검은사막>의 초기 튜토리얼 구성요소를 비교 분석하였 다. 마지막으로, 분석 결과를 바탕으로 모바일 RPG 튜토리얼 구성요소에 대해 제안하였다. 첫 째, 모바일이나 PC 환경과 상관없이 RPG 튜토리얼 구성요소에 모두 포함되는 요소인, RPG 튜토리얼의 기본적인 요소를 포함한다. 둘째, 모바일 RPG의 경우 가상 인터페이스를 통한 게 임 플레이의 비중이 크다는 점을 고려하여 가상 인터페이스를 활용한 매개적 소통 방법에 대 한 요소를 게임에 맞게 포함한다. 셋째, 가상 인터페이스를 통한 게임 플레이가 게임 세계 자 체에 대한 몰입을 방해하는 부작용을 초래하지 않도록 플레이어의 직접적인 행동에 따른 NPC 리액션에 대한 요소를 강화하고, NPC Status와 몬스터에 대한 배경 스토리 정보를 포함한다.

The tribology characteristics of the graphene coated PA6 were evaluated with scratch experiments. As a result, the following conclusions were obtained. The PA6 of the graphene coating shows a 0.1 improvement in friction coefficient and a lower abrasion depth than PA6 in the variable pressure-type scratch experiments. PA6 of the graphene coating showed a lower friction coefficient of 0.2 or more than PA6 in the friction coefficient in the static pressure scratch experiments, indicating that wear resistance was improved. In both the variable and the static pressure type scratch experiments, the tip depth of graphene-coated PA6 shows a thinner wear depth than PA6, showing the effect of graphene. The graphene content showed excellent tribology characteristics at 3%, and there was no difference in tribology characteristics at higher contents.

The purpose of this study was to investigate nutritional and functional ingredients and antioxidant activity after fermenting rice bran using Lactobacillus brevis for 24, 36, and 48 hours. The results of the analysis of the nutritional ingredients revealed that there was no significant difference in the carbohydrate, crude protein, crude fat and ash content regardless of the fermentation process and fermentation time. The amount of dietary fiber was significantly different between the unfermented and fermented rice bran and was observed to be the highest after a 48-hour fermentation. The -oryzanol, gamma-aminobutyric acid (GABA) and total phenolic contents were significantly higher in the fermented rice bran compared to the unfermented rice bran (p<0.05) and the GABA and total phenolic contents increased significantly as the fermentation time increased (p<0.05). The 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis-3-ethylbenzothiazoline-6- sulfonic acid (ABTS), superoxide and hydroxyl radical scavenging activities used to measure antioxidant effects significantly increased as the fermentation time increased (p<0.05). From these results, it was confirmed that the antioxidant effect and functional components, namely -oryzanol, GABA, and the total phenolic content of rice bran improved with fermentation. Based on these results, fermented rice bran could be presented as a functional material for use in high value-added industries.

수인성 질산 노출에 대한 향어의 독성 영향을 확인하기 위해 96시간 동안 0, 4, 20, 100, 500 및 2,500 mg NO3 -/L의 수인성 질산에 노출을 실시하였다. 질산 96시간 급성 노출에 의한 향 어의 반수치사농도(LC50)는 1,433.54 mg NO3 -/L로 나타났다. 혈액학적 성상을 통해 수인성 질 산 노출이 향어에게 미치는 생리학적 변화를 평가하였으며, RBC count는 유의적인 감소를 나 타내었다(p < 0.05). 혈장 무기성분을 통해 수인성 질산 노출에 따른 향어의 이온 조절 능력 변화를 평가하였으며, 혈장 무기성분에서 calcium과 magnesium은 유의적으로 감소하였다(p < 0.05). 혈장 유기성분을 통해 수인성 질산 노출로 인한 향어의 건강도와 스트레스 상태를 평 가하였으며, 혈장 유기성분인 glucose는 유의적인 증가를 나타내었다(p < 0.05). 혈장 효소성분 을 통해 수인성 질산 노출로 인한 간 손상도 및 효소 활성의 변화를 평가하였으며, 혈장 효소 성분인 AST, ALT 및 ALP는 높은 수준의 수인성 질산 노출에서 유의적으로 감소하였다(p < 0.05). 본 연구의 결과는 C. carpio nudus에 대한 수인성 질산 노출이 생존율, 혈액학적 성상 및 혈장성분에 독성으로 영향을 미칠 수 있음을 의미한다.