Background: Ankle sprains occur frequently among humans who undertake various body movements. Diverse walking environments and dual tasks, that can affect ankle sprains, have been studied. However, there is a lack of research on inter-trial variability according to the changes in gait speed. Objects: The purpose of this study was to compare the adaptive ability of walking between the subjects with chronic ankle instability and healthy adults while performing a walking task with different walking speeds. Methods: In this study, 24 people in the chronic ankle instability group and 24 people in the healthy ankle group were selected as subjects. The length of the pre-measurement and the actual walking measurement were both set to 4.6 m. Once the subjects entered the measurement section, they changed their gait speed according to the randomly assigned speed change. Gait was measured twice and the average value was used for the analysis. Results: The coefficient of variation (CV) of cycle time in subjects with chronic ankle instability showed a significant difference in all cases except when the subjects changed their speed from preferred to slow and from slow to preferred. The CV of step length demonstrated a significant difference in all cases except for the change from slow to preferred and from preferred to fast. The cycle time and step length differential showed a significant difference only when the subjects changed the speed from slow to fast. Conclusion: The subjects with chronic ankle instability were found to have significantly reduced walking adaptability while performing inter-trial variability tasks with different gait speeds compared to healthy subjects.

본 연구는 일회성 발목가동성 운동프로그램이 만성적인 발목불안정성(CAI)에 나타나는 발목가 동범위와 통증 수준에 미치는 영향을 확인하는데 목적이 있다. 연구 대상자는 발목불안정성 설문지 검사에 서 좌, 우측 평균 점수가 24점 이하인 성인여성 20명을 선정 하였으며 집단은 일회성 발목 가동성 운동프 로그램 집단(Ankle mobility exercise program, AE, n=10)과 대조군(CON, n=10)으로 구분하였다. AE 처 치는 일회성 운동에 대한 반응을 확인하기 위해 좌·우측 발목을 각각 1회(20분) 실시하였으며 처치 전후 발목불안정성 검사, 통증 및 발목가동범위를 확인하였다. 먼저 AE 프로그램을 실시한 AE 집단의 통증 수 준은 사전과 비교하여 사후 유의하게 감소하는 것으로 나타났다(p<.01). 또한 AE 프로그램 처치한 AE 집 단에서 배측굴곡이 사전과 비교하여 증가하는 것으로 나타났다(p<.05). 이러한 결과를 종합해 보면 일회성 발목 가동성 운동 프로그램은 CAI에서 나타나는 발목 통증과 발목의 가동범위를 개선시켜 결과적으로 발 목 불안정성을 완화시킬 수 있는 효과적인 운동 중재 방법이라고 생각된다.

목적 : 본 연구는 웨스턴 온타리오 어깨 불안정 지수(Western Ontario Shoulder Instability Index: WOSI)를 한국어로 번역하고 측정 속성을 조사하고자 하였다. 연구방법 : 번역은 번역과 역번역 과정을 포함하는 다수의 문헌에서 사용되고 있는 가이드라인에 따라 진행되었다. 연구대 상자는 한국어판 WOSI (K-WOSI)와 Quick Disabilities of the Arm, Shoulder and Hand for Koreans (K-QuickDASH) 검사를 수행하였으며, K-WOSI는 일정한 시간이 지난 후에 같은 대상자에게 반복 측정되었다. 연구자 는 측정결과를 활용하여 내적일치도, 검사·재검사 신뢰도, 동시타당도, 바닥 및 천장 효과를 분석하였다. 결과 : 16명의 환자가 연구에 참여하였으며, 총점 분석 시 내적일치도(Cronbach’s alpha = 0.97)와 검사·재검사 신뢰 도(Pearson’s r = 0.86, Intraclass Correlation Coefficient = 0.92)가 통계학적으로 유의하였다. 평가의 하위 영역 간의 신뢰도 분석 시에도 통계학적으로 유의한 결과가 확인되었다. 또한 K-WOSI와 K-QuickDASH의 상관성이 높았 으며(Pearson’s r = 0.88), K-WOSI의 바닥 및 천장 효과가 발생하지 않았다. 결론 : 본 연구에서 K-WOSI가 어깨가 불안정한 환자들의 삶의 질을 평가하는데 있어 신뢰도와 타당도가 높은 평가로 확 인되었다.

Preserving intact genetic material and delivering it to the next generation are the most significant tasks of living organisms. The integrity of DNA sequences is under constant threat from endogenous and exogenous factors. The accumulation of damaged or incompletely-repaired DNA can cause serious problems in cells, including cell death or cancer development. Various DNA damage detection systems and repair mechanisms have evolved at the cellular level. Although the mechanisms of these responses have been extensively studied, the global RNA expression profiles associated with genomic instability are not well-known. To detect global gene expression changes under different DNA damage and hypoxic conditions, we performed RNA-seq after treating human cervical cancer cells with ionizing radiation (IR), hydroxyurea, mitomycin C (MMC), or 1% O2 (hypoxia). Results showed that the expression of 184–1037 genes was altered by each stimulus. We found that the expression of 51 genes changed under IR, MMC, and hypoxia. These findings revealed damage-specific genes that varied differently according to each stimulus and common genes that are universally altered in genetic instability.

Purpose: 본 연구의 목적은 본 연구의 목적은 2주간의 회전근개의 강화운동이 회전근개의 근육 두께, 견봉하 공간, 어깨 불안정성에 미치는 영향을 알아보고자 하는 것이다. Methods: 근골격계 질환이 없는 대상자 35명을 대상으로 수행하였으며, 횡격막 호흡을 하는 그룹과 횡격막 호흡을 하지 않는 그룹으로 나누었으며, 두 그룹 모두 필라테스를 수행하였다. 실험에 사용한 기기로는 Ultrasonography(US), Pulmonary function tests(FEV1 / FVC), Bioeletic Impedance Analysis, Sit and reach test를 사용하였다. 근골격계 질환이 없는 대상자 20명이 실험에 참여하였다. 근력 강화 운동은 2주 동안 주 5세트, 총 50세트 실시하였으며, 운동은 풀캔, 빈캔, 외회전 운동으로 진행하였다. 초음파를 이용하여 극상근과 극하근의 근육 두께와 견봉하 공간의 변화를 확인하였다. CSMI는 가시위근과 가시아래근의 근력을 평가하는 데 사용되었다. 정규성 검증을 실시한 후, 반복측정분산분석 (repeated measures of ANOVA)를 사용하여 운동 전, 1주후, 2주후를 비교하였다. 사후 분석을 위해 Fisher’s LSD를 실시하였다. Results: 근력의 비교에서 운동 2주 후 측정 시 내회전에서 유의한 차이가 있었다 (P <0.05). 외회전에서는 유의한 차이가 없었다 (P >0.05). 근육두께에서는 가시위근과 가시아래근의 근육 두께는 유의한 차이가 없었다 (P >0.05). 또한 봉우리밑 공간에서도 유의한 차이가 없었다 (P >0.05). Conlusion: 결론적으로, 빈캔 운동과 풀캔 운동, 측면 외회전 운동은 어깨관절 안쪽돌림의 근력 강화에 긍정적인 효과가 있었다

Background: Since chronic ankle instability (CAI) can adversely affect postural control, core stability exercises have been investigated to improve postural control. However, only a few studies have focused on kinetic chain exercises. Objectives: To investigate the effects of open kinetic chain (OKC) and closed kinetic chain (CKC) core stability exercises on static and dynamic balance abilities and vertical jump height in CAI patients. Design: Randomized controlled trial. Methods: The 18 participants enrolled in this study were randomly divided into the OKC group (n=9) and CKC group (n=9). Static and dynamic balance abilities and vertical jump height were measured before and after the intervention. The intervention program comprising OKC or CKC core stability exercises depending on the groups was conducted for 30 min twice a week for 6 weeks in 12 sessions. Results: In the OKC group, static measured with the eyes open or closed and dynamic balance abilities were significantly improved after the intervention (P<.05). In the CKC group, dynamic balance ability was significantly increased (P<.05). A significant difference was observed in static balance ability measured with the eyes open between the two groups (P<.05). Vertical jump height was significantly increased after the intervention in both groups (P<.05). Conclusion: OKC and CKC core stability exercises improve static and dynamic balance abilities and vertical jump height in CAI patients. Specifically, the OKC core stability exercise was more effective in enhancing static balance ability than the CKC core stability exercise.

Background: Postural control deficit is a major characteristic in patients with chronic ankle instability (CAI). Elastic ankle tapings are commonly used to facilitate postural control in patients with CAI as well as prevent relapse of a lateral ankle sprain. However, equivocal evidence exists concerning the effect of elastic ankle taping on postural control. Objects: This study aimed to evaluate the effects of elastic ankle tapings using kinesio taping (KT) and dynamic taping (DT) on static and dynamic postural control in patients with CAI. Methods: Fifteen subjects with CAI were participated in this study. The participants performed tests under three conditions (barefoot, KT, and DT). Static postural control was evaluated using the one-leg standing test (OLST) and dynamic postural control using the modified Star Excursion Balance Test (mSEBT). One-way repeated-measures analysis of variance was used to compare center of pressure (CoP) data and normalized mSEBT reach distances among the three conditions (with α = 0.05). Results: The CoP parameters (path length, ellipse area, and mean velocity) of the OLST significantly decreased on applying KT and DT compared with those when barefoot. The normalized reach distances in the anteromedial (AM), medial (M), and posteromedial (PM) directions of the mSEBT significantly increased with DT compared to that in the control condition. Further, the higher reach distances with KT compared with those in the control condition were obtained in the M and PM directions of the mSEBT. No significant differences were identified in any of the OLST and SEBT parameters between the two different taping applications. Conclusion: KT and DT improved static postural control during the OLST compared with the control condition. Moreover, these tapes improved dynamic postural control during the mSEBT compared to the control. Therefore, elastic ankle tapings are useful prophylactic devices for the prevention and treatment of ankle sprain in people with CAI.

연소실 내 공조현상으로 인해 발생되는 열음향 불안정성은 안정적인 연소시스템을 구현하기 위해 해결해야 하는 고질적인 문제로 제기되어 왔다. 열음향 불안정성은 크게 1차 2차 열음향 불안정성으로 나뉘며, 본 연구에서는 열음향 불안정성 중 2차 열음향 불안 정성의 천이에 관해 열손실이 미치는 영향에 대한 실험적 연구를 진행하였다. 2차 열음향 불안정성을 발생시키기 위해 한쪽 끝이 열린 1/4 파장 공명기를 채택하여 수직으로 설치하였고, 공명기 내부에는 예혼합 가스를 주입하였다. 또한 공명기 상단으로 발생하는 열손실 효과를 비교하기 위해 추가적으로 외부 동축류 관을 설치하였다. 연료 농후조건의 예혼합 가스만을 채택하여 주입하였기 때문에 동축관 에 주입되는 기체에 따라 공명기 상부에 추가적인 확산화염이 형성될 수 있다. 그 결과 확산화염이 발생되었을 경우 공명기 상단으로의 열손실이 감소하며 2차 열음향 불안정성이 발현되었으며, 확산화염이 억제되어 공명기 상단으로의 열손실이 증가하였을 경우 2차 열음향 불안정성의 발현이 억제되는 결과를 도출하였다.

Background: Repetitive damage to the ankle joint causes chronic ankle instability, and studies comparing the effects of exercise in open and closed chains as a treatment method are very rare. Objectives: To investigate the effects of open and closed kinetic exercises on muscle activity and dynamic balance of ankle joint in adults with chronic ankle instability. Design: Single-blind randomized controlled trial. Methods: The selected 30 subjects are randomly divided into open kinetic chain exercise experimental group (EGⅠ, n=10), closed kinetic chain exercise experimental group (EGⅡ, n=10), and stretching control group (CG, n=10). Open and closed kinetic exercises lasted 30 minutes three times a week for six weeks and stretching exercises performed four actions for 20 seconds and five sets. The measurement tools using surface electromyography to measure muscle activity in the ankle joint. The dynamic balance of the ankle was evaluated using the Y-Balance test. Results: Following the intervention, closed and open kinetic chain exercise group showed significant difference in tibialis anterior and gastrocnemius muscle activity and dynamic balance (P<.05). However, no significant difference in tibialis anterior and gastrocnemius muscle activity and dynamic balance between closed and open kinetic chain exercise group (P<.05). Conclusion: This study provides evidence that closed and open kinetic chain exercise can be presented as an effective exercise for the muscle activity of ankle muscle and dynamic balance of the subject with chronic ankle instability.

Background: Ankle sprain is one of the most common musculoskeletal injuries in the sports population or during usual daily life activities. The sprain can cause functional ankle instability (FAI), and it is very important to treat FAI. However, the optimum intervention method for FAI has yet to be determined. Objects: This study investigated the impact that virtual reality (VR) training program on balance with ankle kinesio taping for FAI. Methods: Twenty-two people were selected for the study and randomly divided into the experimental (n = 11) and the control group (n = 11). The experimental group had attached kinesio taping on the ankle and then implemented a virtual reality exercise program for 30 minutes a day. Nintendo Wii Fit Plus was used for the VR intervention three times a week for four weeks. The control group performed only two measurements without intervention. Results: There were no statistically significant differences in overall, anterior-posterior (AP), medial-lateral (ML) index of the static balance, and significant differences in overall, AP, ML index of the dynamic balance when taping and VR exercise were applied at the same time (p < 0.05). There were no significant differences in overall and ML index of static and dynamic balance compared with before and after assessment between the experimental and the control group, and found differences in AP index of static and dynamic balance (p < 0.05). Conclusion: Kinesio taping may not influence the balance of FAI as great as people expected. VR approach does not affect the static balance of FAI, but it influences dynamic balance in overall, AP, ML index. The authors suggest that VR-based exercises can be used as an additional concept in clinicians for FAI or as part of a home program because the exercises still have limitations.

Background: Chronic ankle instability is a common injury that decreases balance and negatively affects functional movements, such as jumping and landing. Objectives: To analyze the effect of taping types and jump heights on balance with eyes open and closed during jump landings in chronic ankle instability. Design: Within-subject design. Methods: The study involved 22 patients with chronic ankle instability. They performed both double-leg and single-leg drop jump landings using three conditions (elastic taping, non-elastic taping, and barefoot) on three different jump platforms (30, 38, and 46 cm). Balance was measured using the Romberg's test with eyes open and closed. Results: Interaction effect was not statistically significant. Balance with eyes open and closed was significantly improved in both the elastic taping and non-elastic taping conditions compared to the barefoot condition. There was no significant difference according to the jump height. Conclusion: Individuals with chronic ankle instability demonstrated increased balance ability with eyes open and closed when jump landing. Elastic taping and non-elastic taping on the ankle joint can positively affect balance during landing in individuals with chronic ankle instability.

Background: Ankle sprain in the Lead Leg Side (ALLS) is common in fencing athletes, and studies comparing the ankle range of motion (ROM) and strength of both legs are insufficient. Objectvies: To compare the ankle ROM and hip strength between two legs in fencing athletes who has ankle instability in the lead leg side. Design: Cross-sectional design. Methods: Seven fencing athletes with ankle instability participated in this study, and they randomly assigned into ankle in the Lead Leg Side (ALLS) and ankle in the Rear Leg Side (ARLS). Instability was determined by the Cumberland Ankle Instability Tool (CAIT), and then joint ROM and hip muscle strength were measured. Results: There were significant differences in dorsiflexion ROM, hip strength (extension and abduction) between the ALLS with ankle instability and ARLS (P<.05). Conclusion: This study suggests that the ankle ROM and hip muscle strength of ARLS are greater than ALLS in fencing athletes with ankle instability.

1,3,5-benzenetricarbonyl trichloride는 3개의 아실클로라이드가 벤젠고리 1,3,5에 위치한 화학물질로, 높은 가교도 를 통한 물리적⋅화학적 특성을 요구하는 곳에 사용하는 중요한 화학물이다. 특히 일정 기공크기를 갖고 있는 3차원 구조체 형성이 가능하여, 다양한 분리 정제 분야에 사용되고 있다. 하지만 아실클로라이드의 높은 반응성은 반응속도가 빠른 장점을 갖고 있지만, 다른 측면에서는 일정한 성능을 가질 수 있도록 화학적 제어가 어려운 점도 있다. 따라서 본 연구에서는 1,3,5- benzenetricarbonyl trichloride의 화학적 변화가 어떻게 분리막 성능에 영향을 주는지 관찰하였다.