엑스선유방촬영술은 다양한 유방질환 중 석회화 병변을 진단하는데 가장 효과적인 방법이다. 환자의 의 료피폭 저감과 진단에 필요한 최적의 영상을 얻기 위해서는 성능유지를 지속적으로 관리해야 한다. 엑스선 유방촬영술에서 엑스선을 발생시키는 양극의 경사각도는 중심선을 기준으로 하기 때문에 조사야 내의 위 치에 따라 엑스선관의 유효초점이 미세하게 달라질 수 있어 공간분해능의 차이가 발생할 수 있다. 본 연구 에서는 디지털 엑스선유방촬영장치에서 검출기 위치에 따른 LSF를 측정하여 MTF를 계산함으로써 공간분 해능 변화에 대해서 연구하였다. 와이어 직경에 대한 변화에서 50 ㎛ 직경의 와이어의 경우 가장 높은 공 간주파수 값을 나타냈으며 검출기의 픽셀보다 작은 직경을 갖는 와이어를 사용해야 검출기의 공간주파수 에 따른 응답을 바르게 구할 수 있다는 것을 알 수 있었다. 조사야 내의 검출기의 위치에 따라서 공간주파 수는 중심부분의 와이어가 나머지 와이어보다 우수한 MTF 특성을 보였으나, 그 차이는 미소하게 나타났 다. 또한 중앙부분에서 반치폭 또는 유효초첨이 가장 작게 나타났으며 중앙에서 벗어날수록 반치폭이 증가 하여 공간분해능이 낮아진 것으로 나타났다.

Melanin is produced by melanocytes of the melanoepidermic unit and other cell types. These cells secrete and distribute the melanin pigment, which provides protection from ultraviolet radiation. In this study, the inhibitory activity against tyrosinase and melanin biosynthesis in B16F10 melanoma cells and anti-wrinkling effects on human dermal fibroblasts of Dendrobium speciosum ethanol extract were investigated. The Dendrobium speciosum extract inhibited melanin biosynthesis and tyrosinase activity in a dose-dependent manner in comparison with an untreated control group. Treatment with the Dendrobium speciosum extract suppressed α-MSH-stimulated melanogenesis in B16F10 cells and the dendrite outgrowth of melanocyte/melanoma cells. The α-MSH-induced mRNA expression of tyrosinase-related protein-1 (TRP-1), tyrosinase-related protein-2 (TRP-2) and microphthalmia-associated transcription factor (MITF) was significantly attenuated in a concentration-dependent manner by Dendrobium speciosum treatment. In addition, Dendrobium speciosum treatment increased production of type I procollagen synthesis in human dermal fibroblasts. Dendrobium speciosum ethanol extract exhibited a potent inhibitory effect on melanin biosynthesis, tyrosinase activity and increased procollagen synthesis. These results indicate that Dendrobium speciosum shows promise as an ingredient in cosmeceutical products due to its whitening and anti-wrinkle effects.

It is important that structure's exact damage analysis and decision-making for recovery when natural disasters cause damage on SOC structure. There are many related studies using geo-spatial data like satellite and aerial images. Recently the interest has increasing about utilizing UAV(Unmanned aerial vehicle). But there are little studies related it. Therefore, we present the extraction method of the shape changes of structure damage using UAV images.

In a pretensioned concrete member, the effective prestress is not fully developed in a certain length from the end of the member, which is defined as transfer length. Because of its complex mechanism, previous transfer length models are mostly empirical and provide very different results. In this study, the Adaptive Neuro-Fuzzy Inference System(ANFIS) was introduced to estimate the transfer lengths of pretensioned concrete members. A total of 209 experimental data has been used to train ANFIS, and the trained ANFIS algorithm estimated the transfer lengths of test specimens very accurately.

저자들은 비파괴시험에 의한 고강도콘크리트의 강도 예측식을 제안하기 위하여 실험적 연구를 수행하였다. 본 연구에서 사용된 콘 크리트의 설계압축강도는 40~80 MPa 범위이며, 압축공시체를 제작하여 반발경도법과 초음파 속도법으로 실험한후 KS기준에 따라 압축강도 실험을 실시하였다. 실험결과는 기존의 연구자들에 의하여 제안된 다양한 실험예측식들과 비교분석하였다. 실험결과 고강도 콘크리트에서도 반발경도법과 초음파속도법의 경우 간편성과 신뢰성에 있어 콘크리트 강도를 측정하기에 충분한 유용성을 확보한 것을 확인할 수 있었다. 기 존식들과의 비교를 통하여 고강도 콘크리트에 적합한 강도예측식을 제안하였으며, 실험결과에 대한 충분한 신뢰성을 확보한 것으로 판단되 어, 향후 고강도 콘크리트 구조물에 적용할 수 있을 것으로 판단된다.

Ground echo is radar return from stationary targets such as buildings and trees. Wind vectors from the wind profile radar in Gangneung are affected by ground echoes due to the complex mountainous terrain located to the west and the south. These ground echoes make a spurious peak close to the direct current (DC) line signal in Doppler spectra. Wind vectors polluted by ground clutters were determined from spectra of oblique beams. After eliminated the terrain echoes, the accuracy of wind vector compared with radiosonde was improved about 68.4% and its relative coefficient was increased from 0.58 to 0.97.

This study investigated the effect of electron beam (EB) treatment on the microbial reduction of dried laver (Porphyra tenera) and identified EB-resistant bacteria from the treated dried laver. After EB treatments of 4 kGy and 7 kGy, the numbers of total bacteria and EB-resistant bacteria were measured using tryptic soy agar and mannitol salt agar, respectively. The morphological and biochemical characteristics of each isolated EB-resistant bacteria were investigated and these bacteria were identified. Compared to the control (1.5±0.2)×106 CFU/g, the total bacterial number was significantly decreased to (5.4±0.5)×104 CFU/g and (1.1±0.6)×104 CFU/g after EB treatments of 4 kGy and 7 kGy, respectively. With a higher EB dosage, the number of red colonies was almost same, whereas the number of yellow colonies was significantly decreased to (3.3±1.2)×103 CFU/g and 0 CFU/g for 4 kGy and 7 kGy, respectively. All red and yellow colonies were gram-positive cocci, catalase-positive, and resistant to 3% and 5% NaCl media. From the 16S rDNA sequence analysis, yellow and red colonies were identified as either Micrococcus flavus or M. luteus, with 99% similarity for the yellow colonies, and Deinococcus proteolyticus and D. piscis, with 99% and 97% similarity for the red colonies, respectively.

청각장애인의 시청각 매체인 TV이용에 있어서 문제가 되는 것은 소리를 들을 수 없기 때문 에 프로그램 내용의 이해도가 현저히 떨어진다는 것이다. 그 이해도를 증대시켜 접근의 편의성 을 높일 수 있는 연구의 필요성을 가지게 된다. 본 논문에서는 자막방송에 대해 자막을 자동으로 생성하는 방법을 제안하였다.

Obesity is a pro-inflammatory state that contributes to the development of metabolic disorders such as hyperlipidemia, insulin resistance, type 2 diabetes, non-alcoholic fatty liver, and cardiovascular disease. In this study, we evaluated the inhibition of adipogenesis in 3T3-L1 cells and in high-fat diet (HFD)-induced obese mice by Peucedanum japonicum Thunberg L. water extract (PJT). Lipid accumulation measurement indicates that PJT markedly inhibited adipogenesis in a dose-dependent manner. RT-PCR results demonstrated that the mRNA expression of adipogenic transcription factors such as peroxisome proliferator-activated receptor-γ (PPARγ) and CCAAT/enhancer binding protein- α (C/EBPα) in 3T3-L1 cells were significantly down-regulated by PJT treatment. Oral administration of PJT (100, 300, and 500 ㎎/㎏, b.w/daily for 4 weeks) was conducted in high-fat diet induced obese mice and C57BL/6 mice. The PJT-administered group of HFD-induced mice had a lower body weight gain, along with decreased serum levels of glucose, triglycerides, and total cholesterol compared with the control mice, however, the HDL-cholesterol/total cholesterol ratio was increased. Furthermore, the elevated mRNA expression levels of adipogenesis related genes in the white adipose tissue of obese mice were significantly suppressed by PJT. These results indicate that PJT exhibits anti-obesity effects in obese mice by decreasing in serum lipid levels and lipogenesis related gene.

Background : Irregular meals and insufficient exercise are major modern lifestyle-related risk factors for constipation. This study aimed to examine the effects of the aqueous extract of Dendrobium speciosum var. (DM) on the improvement of intestinal function and prevention of constipation in rats. Methods and Results : Constipation in rat was induced by loperamide (4 ㎎/㎏) injection for 5 days and rats were randomly assigned to the following groups: normal control rats (NOR), constipated rats (LOP induced) and constipated rats supplemented with dulcolax-S (POS), DMSG, 100 ㎎/㎏ (DMSG-100), 300 ㎎/㎏ (DMSG-300) and 500 ㎎/㎏ (DMSG-500). The DMSG groups showed increments in the frequency and amount of stools compared to the LOP group. Loperamide treatment markedly reduced the water content of feces, whereas DMSG administration significantly increased fecal water contents. Moreover, DMSG improved intestinal transit speed in constipated-rats. Alcian blue staining revealed increased mucus production by crypt cells and mucus contents in feces and the mucosal surface. Conclusions : In summary, DM extraction significantly improves intestinal function in rats, which indicates the effectiveness of this extract in the prevention and treatment of constipation.

This study analyzed fluctuations of ground water level of ground water wells developed in Seongsan watershed of Jeju Island until 2013 using MODFLOW, a numerical analysis model. Ground water level shows greater fluctuations from increase of pump capacity compared to the number of ground water wells. The development of ground water at the top of watershed was found to have direct influence on ground water level. Ground water wells developed until 2013 were used to continue pumping for 50 days, and ground water level of coastal region was reduced below 50% compared to the standard water level. In addition, the range of fluctuation of water level was large in the east coast region, which represents the direction of flow of ground water.

확률강우량은 수공구조물 설계와 도시방재를 위한 기준 등으로 활용되고 있어, 확률강우량의 산정은 매우 중요하다. 특히 소방방재청에서는 확 률강우량으로 우리나라 시·군 단위로 지역방재성능목표를 설정하고 이에 대한 방재성능평가 및 방재성능목표 달성을 위한 개발계획 수립 시 활용 하고 있다. 본 연구에서는 현재 시·군 단위로 설정되어 있는 목표 강우량을 구(區) 단위로 산정하고자 기상청의 지상기상관측지점(SSS, Surface Synoptic Stations)과 방재기상관측지점(AWS, Automatic Weather Stations)의 강우자료를 활용하여 지점빈도해석 및 지수홍수법을 이용한 지역빈도해석을 통해 지속시간 1시간, 2시간, 3시간 목표강우량을 산정하였다. 이는 서울지역의 지자체별 방재성능 평가 및 방재관련 업무에 참고 자료로 활용할 수 있을 것으로 판단되며, 향후 방재성능목표 설정에 크게 기여할 것으로 판단된다.

본 연구는 고강도 섬유보강 시멘트 복합체(UHSCC) 접착성능을 평가하는 것이 목적이다. Direct shear test를 통해 압축전단접착강 도를 측정한 결과 NC(보통강도콘크리트)+ NC 실험체(150×150×150)에서는 모든 수준에서 유사한 압축전당접착강도를 나타내었고, 반 면 UHSCC+UHSCC에서는 지연타설 30분 후부터 0분에 비해 압축전단접착강도가 낮아지는 것을 확인할 수 있었다. 이를 통한 접착면의 파괴 모드를 분석한 결과 NC+NC 에서는 모든 수준에서 비계면 파괴를 보였고 UHSCC+UHSCC에서는 30분, 60분, 90분 시험체에서 계면파괴가 일 어났다. NC 및 UHSCC의 타설면을 XRD 시험을 통해 분석한 결과 NC 시험체에 비해 UHSCC의 시험체 에서 많은량의 SiO2의 성분이 검출되 는 것을 알 수 있었고 UHSCC에서 나타난 코팅막의 주성분의 대부분은 SiO2로 사료된다. 따라서 본 연구에서 사용된 UHSCC는 지연타설 30분 후 부터는 접착성능의 저하로 구조체로서의 사용이 어렵다고 판단된다. 금후 연구에서는 콜드조인트 발생 부위의 면처리 방법을 통한 접착성 능 향상이 필요하다고 사료된다.