An increasing trend embracing the 2030 generation mindset through the new word ‘newtro’, which means reinterpreting the past and selling it in the present, has been gaining traction. The 2030 generation who seek new experiences and desserts is growing. The unique dessert market is expected to continue to grow in the future. Thus, this study devised a pine needle madeleine. Madeleines were made by varying the proportions of pine needle powder added to 0%, 1%, 3%, 5%, and 7%, and specific gravity, moisture, color, physical properties, and antioxidant properties were measured. The L-value decreased significantly (p<0.001) as the amount of pine needle powder added increased, and the a-value increased (p<0.001). The total polyphenol content, DPPH, and ABTS gradually increased significantly (p<0.001). Through this study, it was possible to confirm the quality and characteristics of madeleines using pine needle powder, which has excellent antioxidant properties, and it will become basic data for the development of various desserts using pine needle powder.

To improve the shelf-life of Centella asiatica, Centella asiatica was treated with gel packs containing slow-released chlorine dioxide (ClO2) gas at 3-5 ppm for 20 days at 4℃. The weight loss rate, as well as the changes in pH, color, and texture of the treated samples, were investigated. The weight of the control and ClO2 gas-treated samples was decreased during the storage period. The change in weight of the control was slightly faster than that of the samples treated with 3 and 4 ppm ClO2 gas. The pH of the control and the ClO2 gas treated samples were decreased during the storage period and there was no significant difference between the control and ClO2 gas treated samples. Concerning color (lightness, redness, and yellowness) changes of Centella asiatica during the storage period, there was no significant difference between the control and ClO2 gas treated samples. The change in shear force in the leaf and stem of Centella asiatica during the storage period was slightly lower in the 4 ppm ClO2 gas treated samples (in the leaf) compared to the control and 3 and 4 ppm ClO2 gas treated samples (in the stem) compared to the control and 5 ppm ClO2 gas treated sample.

As cholesterol intake increases, the prevalence of hypercholesterolemia is also increasing. With increasing food selection considering health, consumption of functional foods that can help health is also expected to increase. Ginger is rich in minerals (such as potassium and magnesium) and antioxidants. Antioxidants have been shown to be effective in lowering blood cholesterol levels. Therefore, we would like to produce madeleines helpful for hypercholesterolemia by adding ginger syrup to madeleines recently consumed as desserts. In this study, the quality and characteristics were analyzed after making madeleine by adding ginger syrup at 0%, 5%, 10%, 15%, and 20%. Baking loss was significantly reduced as the addition amount increased (p<0.001). The pH value decreased as the addition amount increased except for the 5% added group (p<0.001). The b value of the chromaticity showed a significant increase from the 5% addition group (p<0.001). Regarding textures, hardness (p=0.006), gumminess (p=0.001), and chewiness (p=0.001) all decreased as the addition amount increased. Regarding antioxidant activity, polyphenol, DPPH, and ABTS values were significantly increased as addition amount increased (p<0.001). Consequently, Madeleine using ginger syrup rich in antioxidants is expected to help health.

The restraints are used in the intensive care unit as a way to restrict the movement of the whole body or part of the body for the safety of the patient, such as maintaining medical equipment, preventing falls and patient self tube removal through regulating the patient's behavior. However, the physical restraints are used for the physical safety of the patient, but that is cause a variety of physical and psychological complications. Thus, nurses in intensive care units who apply restraint on face an ethical dilemma in the confrontation between the nurse's duty to improve the patient's health and protect the patient's safety and the value of the patient's autonomy and dignity. We have two examples are proposed to identify the ethical dilemma situation faced by nurses, to induce an active attitude towards elimination by establishing exactly restraint - removal criteria. In addition, it is proposed to seek a balance of individual values through active communication between the patient and the medical staff regarding the application of the restraint.

PURPOSES : In this study, the factors affecting the severity of traffic accidents in highway tunnel sections were analyzed. The main lines of the highway and tunnel sections were compared, and factors affecting the severity of accidents were derived for each tunnel section, such as the tunnel access zone and tunnel inner zone. METHODS : An ordered probit model (OPM) was employed to estimate the factors affecting accident severity. The accident grade, which indicates the severity of highway traffic accidents, was set as the dependent variable. In addition, human, environmental, road condition, accident, and tunnel factors were collected and set as independent variables of the model. Marginal effects were examined to analyze how the derived influential factors affected the severity of each accident. RESULTS : As a result of the OPM analysis, accident factors were found to be influential in increasing the seriousness of the accident in all sections. Environmental factors, road conditions, and accident factors were identified as the main influential factors in the tunnel access zone. In contrast, accident and tunnel factors in the tunnel inner zone were found to be the influencing factors. In particular, it was found that serious accidents (A, B) occurred in all sections when a rollover accident occurred. CONCLUSIONS : This study confirmed that the influencing factors and the probability of accident occurrence differed between the tunnel access zone and inner zone. Most importantly, when the vehicle was overturned after the accident occurred, the results of the influencing factors were different. Therefore, the results can be used as a reference for establishing safety management strategies for tunnels or underground roads.

PURPOSES : It is necessary to implement traffic-control strategies for underground roads. In this study, the application criteria for traffic control were developed to minimize actual traffic congestion on underground roads before it occurs. In particular, the traffic congestion judgement criteria and procedure (TJCAP) were developed. They can specifically classify the possibility of traffic congestion underground. METHODS : A microscopic traffic simulation model was used to analyze different scenarios. With the scenario simulation results, a hierarchical clustering analysis was applied to produce quantitative values from the TJCAP for each experimental network case. RESULTS : For network case (a), it was concluded that the possibility of traffic congestion on underground roads increases when the speed of the ground road connected to the main underground road and the connected ground road after the outflow of the ramp section is low. When the connected road is an interrupted facility after entering the underground roads, the red time is long, and when the section travel speed is 15 km/h, the possibility of traffic congestion underground is highest. A cluster analysis based on these results was performed using two techniques (elbow and silhouette) to verify the final classification. CONCLUSIONS : The TJCAP were designed to operate traffic flow with stricter criteria than traffic congestion management on ground roads. This reflects the difference in the driving environment between underground and above-ground roadways.

Hepatic diseases are divided into two types: alcoholic and non-alcoholic. Non-alcoholic liver injury finally induces fatty liver and damages liver function. Many studies have demonstrated that Ecklonia stolonifera has antioxidative, antiinflammatory, and hepatoprotective activities. We conducted a 12-week double-blind, placebo-controlled, randomized trial to examine the efficacy of E. stolonifera extracts (ESE) on biochemical markers of hepatic function. Sixty-five subjects with mild or moderate liver injuries were randomly allocated to receive either 420 mg/d of ESE or a placebo for 12 weeks. Fifty-five participants completed the trial. No significant adverse events were observed among the subjects during the study. The primary end points were changes in plasma levels of aspartate transaminase (AST), alanine transaminase (ALT), and γ-glutamyltransferase (γ-GT). The secondary end points were changes in lipid profile levels, including total cholesterol (TC), triglyceride (TG), highdensity lipoprotein cholesterol (HDL), and low-density lipoprotein cholesterol (LDL). Compared with the baseline, AST and ALT levels decreased significantly in the ESE group compared to those in the placebo group (P<0.001). In addition, γ-GT levels in the ESE group were significantly lower than those in the placebo group (P=0.016). There were no differences in the TC, TG, HDL, and LDL levels between groups. In conclusion, ESE consumption for 12 weeks improved liver parameters in subjects with liver injury. Regular consumption of ESE could maintain liver health in individuals at risk of hepatic damage.

본 연구에서는 3D 프린팅 FDM 방식의 적층 방향에 따라 기계적 물성이 달라지는 이방성 특성을 확인하고 이를 이용하여 위상 최 적설계를 수행하였다. 벤치마크 문제인 자동차 현가장치 부품 중 하나인 로어 컨트롤 암에 대하여 밀도법 기반 위상 최적설계를 수행 하였으며, 외부 하중과 이방성 특성에 따라 위상 최적결과가 다르게 나타나는 것을 확인하였다. 이를 이용하여 최적화된 모델에 대하 여 3D 프린터로 적층 방향을 달리하여 2가지 시험품을 제작하였으며 인장시험을 수행하였다. 시험시 3D 비접촉 변형률 측정기를 이 용하여 변형률을 구하였으며 이를 CAE 응답해석으로 얻은 변형률과 비교한 결과가 정량 및 정성적으로 일치하는 것을 확인하였다. 3D 프린팅 적층 방향을 고려한 위상 최적모델의 인장 실험 결과를 통해 해당 최적설계 방법론의 유효성을 검증하였다.

The fish community in the Seomjin River-Seomjin River Estuary-Gwangyang Bay coast continuum was investigated three times from March 2019 to October 2019. The collected species at the eight sites during the survey period were 49 species belonging to 31 families, including two endangered species. According to Bray-Curtis similarities, observations were divided into four groups based on the fish community composition; two groups (group 1, 2) and two uncategorized groups (group 3, 4). ANOSIM based on spatial and temporal groupings indicated that the spatial differences in fish communities (R=0.398, P=0.001) were relatively more important than the temporal differences (analysis of similarities, R=0.273, P=0.002). In particular, there were significant differences between groups 1 and 2 (analysis of similarities, R=0.556, P=0.001), and similarity percentage analysis revealed that Argyrosomus argentatus (9.4%), Favonigobius gymnauchen (6.9%) and Konosirus punctatus (5.9%) contributed to these differences of fish assemblages for each group. The fish fauna distributed in the Seomjin River-Gwangyang Bay ecosystem were spatially divided and the number of species and number of individuals showed seasonal differences. This study could be a basis for understanding changes in the fish community and implementing conservation and management strategies on major species within a continuous environment of the river-estuary-ocean continuum.

돌기해삼 Apostichopus japonicus는 주요 양식 대상 무척추동물로서 우리나라 연안 해역에 서 식하고 있다. 본 연구는 방류 방법에 따른 단기간의 생리학적 스트레스 정도를 평가하기 위하 여 heat shock protein 90 (HSP90) 유전자의 발현 변화를 실시간 정량적 중합효소연쇄반응법 으로 조사하였다. 어린 돌기해삼을 비닐봉지에 산소 포장하여 30분간 수송하거나 방류 해역의 간조기에 1시간 공기 중에 노출된 실험군의 HSP90 유전자 발현은 대조군의 HSP90 유전자 발현에 비하여 통계학적으로 유의미하게 증가하였다(수송 후 실험군 p=0.001; 간조기 실험군 p=0.032). 어린 돌기해삼을 방류 후 6시간까지 분석한 결과, 선상에서 씨뿌림 방식으로 방류된 6시간째의 개체 및 호스를 통과하여 수중으로 방류된 2~6시간째의 HSP90 유전자 발현율은 대 조군에 비하여 약간 감소하는 경향을 보였다(씨뿌림 실험군 p=0.069; 호스 방류군 p=0.093). 한 편, 잠수부에 의해 수중에서 방류된 어린 돌기해삼은 방류 후 시간이 경과할수록 HSP90 유전 자 발현율은 증가하는 패턴이 관찰되었다(p=0.061). 이상의 결과는 방류된 어린 돌기해삼의 단기간 스트레스 반응 연구와 효과적인 방류 방법의 개발에 HSP90 유전자 발현이 유용하게 사용될 수 있음을 시사한다.

본 연구에서는 2021년 전남, 전북을 대상으로 23개소에서 어류 4종(향어, 비단잉어, 참붕어, 금붕어) 총 1,115마리에 대하여 병원체 감염 여부를 조사하였다. 법정전염병 3종(SVC, Spring viraemia of carp, EUS, Epizootic ulcerative syndrome, and KHVD, Koi herpesvirus disease)을 분 석한 결과, 조사한 모든 시료에서 법정전염병이 검출되지 않아 전라권에서 조사한 잉어과어 류는 청정국 또는 청정지역 선언에 중요한 정보를 제공할 것이다.