Colon cancer has been considered a leading cause of cancer-associated death. Folic acid is a vitamin necessary for cellular physiological functions and cell viability. However, the association between folic acid intake and colon cancer has been examined in several prospective cohort studies are controversial. This study investigated the effects of folate intake on colon carcinogenesis and oxidative stress in an azoxymethane (AOM)/dextran sodium sulfate (DSS) institute for cancer research (ICR) mouse model. Thirty male ICR mice (5 weeks old) were divided into the control group and the experimental group supplied 0.03% folic acid via drinking water (50 mL/week/mouse) for 6 weeks. To induce colonic pre-neoplastic lesions, the animals were subcutaneously injected three times weekly with AOM (10 mg/kg body weight), followed by 2% DSS in drinking water for a week. Folic acid supplementation significantly suppressed the total number of aberrant crypt foci and aberrant crypts. Histological image data showed that folic acid supplementation attenuated neoplastic change. In addition, we measured the thiobarbituric acid reactive substances concentration of dry feces samples to identify the effect of folic acid on reactive oxygen accumulation. The folic acid supplementation group had reduced reactive oxygen species levels in dry feces compared to the control group. In conclusion, these findings indicate that folic acid suppresses colon carcinogenesis and oxidative stress in an AOM/DSS mouse model.

Ocean biogeochemistry plays a crucial role in sustaining the marine ecosystem and global carbon cycle. To investigate the oceanic biogeochemical responses to iron parameters in the tropical Pacific, we conducted sensitivity experiments using the Nucleus for European Modelling of the Ocean–Tracers of Ocean Phytoplankton with Allometric Zooplankton (NEMO-TOPAZ) model. Compared to observations, the NEMO-TOPAZ model overestimated the concentrations of chlorophyll and dissolved iron (DFe). The sensitivity tests showed that with increasing (+50%) iron scavenging rates, chlorophyll concentrations in the tropical Pacific were reduced by approximately 16%. The bias in DFe also decreased by approximately 7%; however, the sea surface temperature was not affected. As such, these results can facilitate the development of the model tuning strategy to improve ocean biogeochemical performance using the NEMOTOPAZ model.

벗초파리기생벌인 A. japonica의 벗초파리 유충의 발육단계에 따른 기생특성과 기생당한 유충과 번데기에서 형태적인 차이를 조사하였다. 또한 A. japonica의 우화기간이 벗초파리 우화일수 보다 더 소요되는 것을 확인하였다. A. japonica는 벗초파리 유충에 효과적인 기생 및 살충 효과를 나타내었으며 벗초파리 방제를 위한 천적으로 활용이 가능할 것으로 보인다.

With the development of the economy and the continuous improvement of people’s living standards, consumers’ increasing demand for safe food has become an inevitable trend of social development. On the one hand, food safety is an urgent social problem needed to be solved in China. On the other hand, the food safety guarantee method based on a traceability system is popular. This paper systematically studies the influencing factors of consumers’ willingness to pay for the extra price of traceable pork in the Yanbian area through empirical analysis. The result showed that consumers’ attitude and subjective norms, and perceived behavior control, have significantly positively affect consumers’ willingness to pay the extra price. Meanwhile, consumers’ perceived risk of traceable pork significantly moderates the effect on consumers’ attitude and willingness to pay an extra price. The results can provide the corresponding reference for government agencies to formulate policies and provide valuable suggestions for enterprises to develop a pork traceability market to realize the development of a pork traceability system in the Yanbian area to ensure consumers’ food safety.

This study employed a bibliometric method to visualize the evolution of corpus-based discourse studies between 1995 and 2019, with a total of 2,174 English-language documents and their 83,184 references collected from Scopus, the Social Science Citation Index, and the Arts & Humanities Citation Index. Co-citation analysis of the predominant authors, references, and publication sources disclosed that the field has expanded over the past 25 years from primary pattern analysis of descriptive and functional grammar to principal investigations of interdisciplinary issues, some of which are central to pragmatics and sociolinguistics. This shift of research focus is also evidenced by keyword analysis. Scholars have been progressively more fascinated by such social issues as news discourse, business discourse, gender and language, and identity. Some emerging topics like social media, media discourse, legal discourse, and the metadiscourse interpersonal model may represent research hotspots and trends in this area. Bibliometric approaches play an important role in providing hands-on evidence-based comparisons and visualizations of previous research outputs using different time bands.

In marine ecosystems, the biosynthesis and catabolism of dimethylsulfoniopropionate (DMSP) by marine bacteria is critical to microbial survival and the ocean food chain. Furthermore, these processes also influence sulfur recycling and climate change. Recent studies using emerging genome sequencing data and extensive bioinformatics analysis have enabled us to identify new DMSP-related genes. Currently, seven bacterial DMSP lyases (DddD, DddP, DddY, DddK, DddL, DddQ and DddW), two acrylate degrading enzymes (DddA and DddC), and four demethylases (DmdA, DmdB, DmdC, and DmdD) have been identified and characterized in diverse marine bacteria. In this review, we focus on the biochemical properties of DMSP cleavage enzymes with special attention to DddD, DddA, and DddC pathways. These three enzymes function in the production of acetyl coenzyme A (CoA) and CO2 from DMSP. DddD is a DMSP lyase that converts DMSP to 3-hydroxypropionate with the release of dimethylsulfide. 3-Hydroxypropionate is then converted to malonate semialdehyde by DddA, an alcohol dehydrogenase. Then, DddC transforms malonate semialdehyde to acetyl-CoA and CO2 gas. DddC is a putative methylmalonate semialdehyde dehydrogenase that requires nicotinamide adenine dinucleotide and CoA cofactors. Here we review recent insights into the structural characteristics of these enzymes and the molecular events of DMSP degradation.

The purpose of this study is to classify the types of decoration techniques used in women’s Chima and Jeogori in traditional Hanbok catalogs from 2010 to 2020, and to analyze the frequency of each type. The method of this study is as follows. This study first investigated the transition of modern Hanbok and decorative techniques by analyzing and classifying such work in previous studies. Based on this, the technique of decorating the Jeogori and Chima that appeared in the traditional Hanbok catalog of the study period was analyzed. The results of the study are as follows. In the case of Jeogori, in the first half of 2010, the decorative technique of a relatively large size was used, and the decorativeness tended to be strong. However, in the late 2010s, the number of decorative techniques used in Jeogori has decreased, and the size of the decorative technique has become smaller and more concise, leading to a tendency to understated decoration. In the case of Chima, techniques to express natural texture by processing threads or fabrics themselves were mainly used rather than techniques to add decoration to the surface, and techniques to express various surface texture tended to develop toward the late 2010s. The change in the decoration technique of Jeogori and Chima appears to be a combination of social, cultural, and economic factors such as a change in consumption culture and a reduction in the wedding market.

테트로도톡신(Tetrodotoxin)은 나트륨 통로를 차단하는 신경독소로 가장 오래되고 강력한 해양독소 중 하나이다. 전통적으로 아시아에서 복어 섭취로 인한 테트로도톡신 중독사고가 많이 발생했었다. 최근 아열대 복어 종과 그 잡종 섭취로 인한 테트로도톡신 중독사고가 아시아 외 지역에서도 산발적으로 발생하고 있다. 그러나 복어 종별 테 트로도톡신 및 유사체의 함량과 기관 내 분포에 대해서는 잘 알려져 있지 않다. 이 총설에서는 식품공전 복어독(테 트로도톡신) 분석법인 쥐를 이용한 생물학적 정량법, 효소 면역측정법, 고압 액체 크로마토그래피-형광검출기, 가스 크로마토그래피-질량분석기를 이용한 분석법의 장단점을 비교하였다. 또한 최근 주로 사용되는 액체 크로마토그래피-질량분석기를 이용한 테트로도톡신과 테트로도톡신 유 사체 분석법을 소개하고 이에 사용된 전처리법, 컬럼 및 이동상을 비교하였다. 또한 복어 종별 테트로도톡신과 그 유사체 함량과 다양한 기관에서의 분포를 정리하였다. 이 총설은 테트로도톡신 분석법과 다양한 복어 종의 테트로 도톡신과 유사체 함량 및 기관에서의 분포를 이해하는데 도움을 줄 수 있을 것이다.