Forward head posture (FHP) is a musculoskeletal disorder that causes neck pain. Several exercise interventions have been used in South Korea to improve craniovertebral angle (CVA) and relieve neck pain. There has been no domestic literature review study over the past 5 years that has investigated trends and effects of exercise intervention methods for CVA with neck pain. This domestic literature review aimed to evaluate the trends and effects of exercise interventions on CVA and neck pain in persons with FHP. A review of domestic literature published in Korean or English language between 2018 and 2022 was performed. Literature search was conducted on Google Scholar and Korea Citation Index by using the following keywords: “exercise,” “exercise therapy,” “exercise program,” “forward head posture,” and “neck pain.” Ten studies were included in this review. All of the studies showed positive improvements after intervention programs that included exercises. Notably, four of these studies demonstrated significant differences in results between the experimental and control groups. Among the 10 studies, nine measured visual analogue scale or numerical rating scale scores and reported significant reductions in pain following interventions, including exercise programs. Five of these studies showed significant differences in results between the experimental and control groups. Furthermore, six studies that used neck disability index exhibited a significant decrease in symptoms after implementing intervention programs that included exercise, and significant differences in results were found between the experimental and control groups. This domestic literature review provides consistent evidence to support the application of various exercise intervention programs to improve CVA and relieve neck pain from FHP. Further studies are warranted to review the effects of various exercise interventions on FHP reported not only in domestic but also in international literature.

Fungal contaminant in the indoor air is one of risk factors that could damage valuable paper-based records preserved in libraries. In the process of monitoring airborne fungi at the Nara Repository, the National Archives, Seoul, Korea, three fungal strains, DUCC 16098, DUCC 17764, and DUCC17767 were isolated from the archive’s air samples. Fungal identification was performed based on the morphological characteristics and phylogenetic analysis of the internal transcribed spacer (ITS), the 28S LSU rDNA, and β-tubulin gene (BenA), and TEF1-α gene. These DUCC 16098, DUCC 17764 and DUCC17767 strains were identified as Clonostachys farinosa, Penicillium cosmopolitanum, and Cephalotrichum purpureofuscum. These species have not been recorded before in Korea. Information on these fungi will help the monitoring and management of airborne fungi in the archival facilities.

Background: Water deer and sika deer, which breed in the wild environment, are known to have similar reproductive physiology mechanisms. Therefore, this study aimed to analyze the differences in uterine development between water deer and sika deer during estrus. Methods: MMPs and uterine development-related factors were analyzed and morphological differences were compared in the uterus of sika deer captured near Russia near Korea and water deer captured in the wild in Korea. Results: In terms of morphological differences in the uterus, the glands that form villus within the endometrium of the water deer were newly developed, and the formation of small glands was high, but the villus and glands of the sika deer were expanded, and the stroma zone in the myometrium was higher than that of the water deer. Development has increased. Additionally, the expression of PAPP-A and VEGF factors was increased in the endometrium of water deer than in sika deer, but the actions of MMPs were increased in sika deer. Conclusions: As a result of this study, there is a significant difference in the development of glands in the endometrium of water deer and sika deer during estrus, and it is believed that there is a significant difference in the development of the uterus due to the physiological effects of estrus between water deer and sika deer. Additionally, it is believed that there will be differences in the timing at which pregnancy can be decided.

본 연구는 온라인 절화 도매 플랫폼에 대한 이용자 인식, 이용 현황을 알아보고, 본 플랫폼의 발전 방향을 제시하기 위 하여 국내 화훼 장식 종사자 300명을 대상으로 조사 연구하 였다. 연구 결과 화훼 장식 종사자의 99%가 온라인 절화 도매 플랫폼에 대해 인지하고 있었으며, 실제 이용 경험 역시 68% 로 높게 나타났다. 이용자들의 서비스 이용 기간은 1~2년이 46.5%로 가장 많았으며 월평균 구매 횟수는 6~15회가 과반 을 차지하였고, 온라인 절화 도매 플랫폼의 1회 기준 소비 금 액은 15만 원 미만이 62.4%로 나타났으나, 오프라인 절화 도 매시장의 사용 빈도 및 소비 금액이 더 높은 것으로 나타났다 (p<0.001). 화훼 장식 종사자들은 절화의 품질(4.85) 및 상품 의 다양성(4.75)이 절화 구매 시 가장 중요한 고려 요인이었 으며, 온라인 절화 도매 플랫폼에서의 상품 구매 시 과거 구매 경험(3.97)과 상품의 사진(3.87)을 보고 절화 품질을 판단하 는 경우가 가장 많았다. 온라인 절화 도매 플랫폼의 가장 큰 장점으로는 시간을 절약(4.39)할 수 있다는 점으로 인식하고 있었으나, 상품 구매 시 불안 요인으로는 절화 신선도(4.30)와 품질(4.02)에 대한 우려가 높은 것으로 나타났다. 온라인 절화 도매 플랫폼에서 제공하는 서비스 품질에 대해 이용자들은 주 문한 상품과 배송 상품이 일치(4.19)하며, 사용하기 쉬운 페이 지로 구성(4.03)되어 있어 구매 과정(4.00)이 편리하다고 응 답하였으나, 상품 품질에 대한 만족도는 모두 보통 이하로 낮 게 나타났다. 온라인 절화 도매 플랫폼과 오프라인 절화 도매 시장에서의 절화 구매 후 만족도를 비교한 결과 온라인 절화 도매 플랫폼에서는 가격과 반품 처리에 있어 오프라인에 비해 강점을 가지고 있었으나, 가장 중요한 절화 구매 결정 요인인 절화 신선도와 상품 다양성에 있어서 오프라인 절화 도매시장 에 비해 부족함을 보였다. 결론적으로 온라인 절화 도매 플랫 폼의 발전을 위해서는 절화 상품 품질 향상 및 다양성 확보가 필요하며 국내 화훼산업의 지속적인 발전과 성장을 위하여 새 로운 화훼 시장 형태에 대한 다양한 추가 연구가 필요할 것으 로 판단된다.

The primary therapeutic approach for Brucella species infections has mainly been based on antibiotic treatment. However, the development of vaccines for brucellosis control remains controversial. Furthermore, there is currently no licensed vaccine available for human brucellosis. This study aims to evaluate the effect of a combination of recombinant protein vaccines against Brucella (B.) abortus infection using a mouse model. Two B. abortus genes, namely dapB and gpm, were cloned and expressed in competent Escherichia (E.) coli DH5α using the pCold-TF vector. Successfully cloned vectors were subjected to PCR amplification using specific primer pairs. The apparent sizes of dapB and gpm were detected at 807 bp and 621 bp, respectively. Besides, the purified recombinant proteins dapB and gpm were detected using SDS-PAGE electrophoresis with correct sizes of 82.86 kDa and 87.61 kDa, respectively. These recombinant proteins were used to immunize mice as a combined subunit vaccine (CSV) to elicit host immunity against B. abortus infection. Mice immunized with CSV exhibited increased proliferation of CD4+ and/or CD8+ T cells at week 7th and 9th before sacrifice, in comparison to the control group. Notably, CSV immunization showed a significant decrease in bacterial burden in the spleen compared to the control group. Altogether, CSV using dapB and gpm induced host adaptive immune response against Brucella infection, suggesting its potential as an effective new subunit vaccine candidate.

In this review, the regulatory mechanisms of autophagy were described, and its interaction with apoptosis was identified. The role of autophagy in embryogenesis, tooth development, and cell differentiation were also investigated. Autophagy is regulated by various autophagy-related genes and those related to stress response. Highly active autophagy occurrences have been reported during cell differentiation before implantation after fertilization. Autophagy is involved in energy generation and supplies nutrients during early birth, essential to compensate for their deficient supply from the placenta. The contribution of autophagy during tooth development, such as the shape of the crown and root formation, ivory, and homeostasis in cells, was also observed. Genes control autophagy, and studying the role of autophagy in cell differentiation and development was useful for understanding human aging, illness, and health. In the future, the role of specific mechanisms in the development and differentiation of autophagy may increase the understanding of the pathological mechanisms of disease and development processes and is expected to reduce the treatment of various diseases by modulating the autophagic phenomenon.

형식은 텍스트와 컨텍스트 사이의 상호작용으로 발생하여, 이중 어느 하나로도 귀결되지 않는 동시에 이들 사이를 조정한다. 형식은 단순히 텍스트의 부산물이 아니고 비가의 예에서처럼 사회적 관습에 종속된다. 동시에 형식은 컨텍스트와 별개로 독립적인 형식의 패턴을 유지한다. 알리와 멀둔에 관한 이 비교연구는 형식이 가진 이러한 역동성을 전제로 진행된다. 두 시인은 역사적 구체성과 구조적 자율성에 기반한 전통적인 시 형식이 가진 역동성을 사용하여 고국이 식민주의 이후 극심한 분쟁을 겪을 때 노스탤지아적 세계관을 구축한다. 두 시인은 스스로를 망명자로 인식하며 가잘, 소네트, 세스티나, 빌라넬과 같은 시 형식을 통해 노스탤지아적 갈망을 표현한다.

In this study, we examined the antagonistic effects of sprout-borne lactic acid bacteria (LAB) on Salmonella enterica serovar Enteritidis. This antagonism is promoted as a means of controlling contamination during sprout production and provides additional LAB for consumers. We isolated a total of 24 LAB isolates in nine species and five genera from seven popular vegetable sprouts: alfalfa (Medicago sativa), clover (Trifolium pratense), broccoli (Brassica oleracea ssp. italica), vitamin (B. rapa ssp. narinosa), red radish (Raphanus sativus), red kohlrabi (B. oleracea var. gongylodes), and Kimchi cabbage (B. campestris var. pekinensis). Based on 16S rRNA gene sequences, the LAB species were identified as Enterococcus casseliflavus, E. faecium, E. gallinarum, E. mundtii, Lactococcus taiwanensis, Leuconostoc mesenteroides, Pediococcus pentosaceus, and Weissella cibaria, and W. confusa. A total of 16 LAB isolates in seven species including E. faecium, E. gallinarum, E. mundtii, L. taiwanensis, L. mesenteroides, P. pentosaceus, and W. cibaria showed antagonistic activity toward S. enterica. The growth inhibition of sprout LAB on S. enterica was confirmed by co-culture. Unexpectedly, sprout LAB failed to suppress the growth of S. enterica in alfalfa sprouts, whereas all LAB strains stimulate S. enterica growth even if it is not significant in some strains. The findings of this study indicate that S. enterica-antagonistic LAB are detrimental to food hygiene and will contribute to further LAB research and improved vegetable sprout production.