This study was conducted to investigate the characteristics of smartphone usage and posture of users during using smartphone. A survey was conducted for 983 smartphone users to understand the association between smartphone usage and including subjective symptoms associated with musculoskeletal disorders. Main results from the survey were as follows; 1) 18.8% of the subjects experienced musculoskeletal symptoms at least at one of body parts. Specifically, 8.1%, 5.6%, 4.1%, and 11.3% of the subjects experienced musculoskeletal symptoms at neck, shoulder, elbow, and hand respectively, 2) The symptoms of musculoskeletal disorders were also associated with amount of text message and time for daily usage of smartphone. Specifically, relative risks of musculoskeletal disorders at hand/wrist/fingers in terms of "amount of text message" and "time for daily usage" for experienced user were 1.425 and 1.368 respectively to inexperienced user. This study identified 'amount of text message' and 'time for daily usage' as the major risk factors of smartphone usage in terms of musculoskeletal symptoms. The results of the study provided a good basis in order to remove or reduce the risks associated with musculoskeletal symptoms due to smartphone usage.

본 연구는 우리나라 남부지방의 대표적 조림 수종인 삼나무(Cryptomeria japonica) 임분을 대상으로 총 15본의 표본목 자료를 이용하여 영급별 줄기밀도 및 바이오매스 확장계수와 바이오매스 추정식을 분석하였다. 본 연구 결과, 영급별(20년 단위) Stand 1, 2, 3의 임목 전체 건중량은 2.93, 168.72, 402.27kg/tree로 나타났고, 지상부 건중량은 6.35, 184.74, 251.35 ton/ha 등으로 나타났으며, 지하부를 포함한 임목 전체 건중량은 7.62, 227.77, 308.14 ton/ha로 나타났다. 줄기밀도는 5% 유의수준에서 영급 단위에 따라 0.38, 0.34, 0.34 g/cm3로 영급이 증가함에 따라 감소하였으며, 바이오매스 확장계수는 각각 3.65∼1.28, 4.07∼1.45로 감소하는 경향을 보였다. 줄기밀도는 통계적 유의성이 나타나지 않은 반면에, 바이오매스 확장계수는 통계적인 유의성이 나타났다.

This study compared data regarding industrial accidents and awareness level for beauty product safety for four main parts of beauty industry such as hair-care, nail-care, skin-care, and make-up. Major risk factors in beauty industry are dust, musculoskeletal disorders, and organic solvent of beauty product in order of percentage. The specific types of industrial accidents in beauty industry are mainly associated with musculoskeletal system such as cuts, sprain, and varicose vein. They are mainly compensated by personal budget. The awareness levels of chemical and heavy metal containment for beauty product by beauty industry employee were 77.2% and 59.1% respectively. Most employee confirmed only important items of labelling requirement of beauty product. Also, most employee did not understand MSDS(Materila Safety Data) for chemicals used in beauty industry. Only 38.1% of beauty industry employee has had safety education while most employee (73.6%) realized that they needed safety education. Also, safety education supervised by KOSHA(Korea Occupational Safety and Health Agency) was the most preferred. This study would be good basis for safe and healthy working environment of beauty industry employee.

This study attempted to evaluate the direct and indirect effect of emotional labor, job and psychosocial stress, and fatigue of beauty industry workers on their musculoskeletal diseases. The findings of this study showed that, among the workers with perceived symptoms of musculoskeletal diseases, the body part with the most commonly occurring symptom was the shoulder, followed by neck, low back, wrist, arm, foot and knee. As for the effect of work-related psychological factors on musculoskeletal diseases, it was found that the workers with musculoskeletal diseases were more affected by emotional labor and fatigue than non-symptom workers. It was also shown that when their job stress increased, the fatigue level also increased, though their psychosocial stress decreased. In addition, it was found that both direct and indirect effects of emotional labor on fatigue were high, and the indirect effect of job stress through fatigue on musculoskeletal diseases was significant.

This study investigated the comprehension of the occupational safety policy direction by job characteristics of the safety managers at 211 workplace selected under the Occupational Safety and Health Act. As for the characteristics of the subjects' firms, there was difference in their perception on the occupational safety policy direction by their region, type, scale, and the existence of labor union. Regarding the job characteristics of the subjects, there was difference in the comprehension of the occupational safety policy direction by their age, experience and department. This study suggests that the government policy as well as the awareness about safety by management and safety managers need to be changed by analyzing the comprehension of occupational safety policy direction by the job characteristics of corporate occupational safety managers.

The purpose of this study lies on reinterpreting the geography books in Joseon dynasty as records of the cities and consequently suggesting directions for further urban research. Geography books of Joseon dynasty are valuable references to understand the national policy, and imply that the focus of the contents is on the system. Especially, military system is an important concept to understand city type in that period, relationships between cities, selection of location, etc. The results of review are as following: First, military system is not a permanent fixture and therefore reflects changes in urban policies along with the history. The system suggests valuable clues on urban development as it is state-run, and closely associated with national land development. Second, counties and prefectures under jurisdiction of district called Eupchi(邑治) had cities as important as or even more important than local government such as Yeong-a(營衙), Jinbo(鎭堡), Yeok(驛: administrative cities). Such special regions need to be studied as other type of cities in Joseon dynasty by defining their architectural characteristics and roles. Third, the relationship of cities such as Eupch, Yeong-a, and Jinbo, was reorganized according to the local military system. Eupchi, administrative city, along with Yeong-a and Jinbo evolved into a military city as it became systematically organized. The characteristics of Yeok needs to be reconsidered in the context of such new inter-city relationship. Fourth, considerations which should be reviewed in the geography based on this concept can be mainly classified into architecture and landscape. This will also lay the foundation, and suggest new directions for further research for Eupchi, Yeong-a, Jinbo, and Yeok. Fifth, description of the geography looks simple at first sight, but with thorough understating on the system, there are chances to interpret objective reasoning of position and landscape in the overall flow of region, area, etc. Bongsu(烽燧), signal-fire, can be an object of comparison with geographical features and position. Furthermore, advantageous position is a historical and geographical element showing the major context of the region.

해외직접투자를 실시하기로 결정한 기업은 어느 국가 시장에, 언제, 어떠한 형태로 진입할 것인가 하는 문제에 직면하게 된다. 이 세 가지 사안에 따라 자원투입 수준과 해외직접투자의 궁극적인 성과에까지 영향을 미치게 되는 만큼 매우 중요한 문제이다. 그러나 다른 두 가지 문제에 비해 진입 시기에 대한 연구는 충분한 관심을 받지 못했다. 이러한 배경 하에, 본 연구는 국가시장의 불확실성이 진입시기와 진입방식에 미치는 영향을 분석함으로써 해외직접투자의 중요한 세 가지 사안을 연결시키고자 한다. 즉 진입 국가의 불확실한 환경이 진입시기와 진입방식에 미치는 효과를 실증적으로 조사하고, 이러한 관계 내에서의 기업자원이 가지는 조절효과 가능성을 발견하며, 진입시기와 진입방식이 상호작용하여 성과에 미치는 영향을 조사하여 기업의 해외시장 진입전략에 관한 결정요인과 결과를 포함하는 통합적인 프레임워크를 제시하고자 한다. 본 연구의 표본은 한국증권거래소에 상장된 기업들의 해외시장진출케이스로 구성되었으며, 가설검증을 위해 중재회귀분석을 실시하였다. 분석 결과, 기업들은 불확실성이 높은 시장으로는 진입시기를 늦추는 경향이 있지만, 기술적 자원이 풍부한 기업에서는 이러한 관계가 약해지는 것으로 나타났다. 한편, 진입시기와 기업성과의 관계에서는 진입방식의 조절효과가 발견되었다.

Recurrence-metastasis status of squamous cell carcinoma of tongue is a challenging oncologic problem. This study examined the expression of E-cadherin/β-catenin cell adhesion complex in squamous cell carcinoma of the tongue through an immunohistochemical study. Twenty samples from 15 patients with squamous cell carcinoma of the tongue, who were treated at the Department of Oral and Maxillofacial Surgery, consisted of primary or recurrent tumors along with matched metastatic lymph nodes were retrieved for immunohistochemical staining and grouped based on recurrence-metastasis status.Differences in stain localization were noted in E-cadherin, β–catenin and phospho β–catenin staining between different tumor groups based on the recurrence-metastasis status. The number of phospho β-catenin stain positive cells was found to have a significant role in survival. E-cadherin confirms its role as a powerful individual differentiation indicator and the role of β-catenin specially the phospho type elicts interest

A blood test is a laboratory analysis performed on a blood sample that is usually extracted from a vein in the arm using a needle, or via fingerprick. They are used to determine physiological and biochemical states, such as disease, mineral contents, drug effectiveness, and organ function. Although the term blood test is used, most routine tests (except for most haematology) are done on plasma or serum, instead of blood cells. Main advantage of using saliva in diagnostics is easy and non invasive sample taking compared to peripheral blood. According to the study published, saliva contains more than 20 percent of the proteins found in blood. The purpose of present study is to compare biochemical enzymes in saliva and in blood serum and to evaluate the usefulness of saliva specimens instead of blood in dental clinic. The saliva from 215 healthy over 50 years of aged people lived in Dong-gu district, Gwangu city was collected and the analysis was performed by six enzyme-linked immunosorbent assays (ELISA). ELISA results were compared with blood chemistry results. The values or patterns on Alanine Aminotransperase (ALT), Aspartate Aminotransperase (AST), Cholesterol and Triglyceride in saliva were not correlated with those in blood serum. However, Albumine and γ-glutamyl transpeptidase (γ-GTP) were followed the positive relationship with blood chemistry. These result showed that detection and identification of Albumine and γ-GTP level could be established by saliva ELISA analysis, so that ELISA assay on saliva could be useful alternative to serum testing.

본 연구의 목적은 경남 산청 지역에 분포하는 40년생 리기다소나무 임분을 대상으로 지상부 바이오매 스와 순생산량에 대하여 분석하고자 하였다. 본 연구의 결과에 의하면, 지상부 바이오매스량은 127.7 Mg ha-1으로 나타났고, 줄기 103.1 Mg ha-1, 가지 17.2 Mg ha-1, 잎 7.4 Mg ha-1으로 나타났으며, 바 이오매스 함량은 줄기목질부 (71.1%) > 가지 (13.5%) > 줄기 수피 (9.6%) > 잎 (5.8%) 순으로 나타났다. 또한 지상부 순생산량은 10.4 Mg ha-1로 나타났고 줄기 3.6 Mg ha-1, 가지 2.2 Mg ha-1, 1년생 소지 1.3 Mg ha-1, 잎 2.8 Mg ha-1로 나타났다. 순생산량 함량은 줄기 목질부 (34.6%) > 잎 (26.9%) > 가지 (21.2%) > 소지 (12.5%) > 줄기 수피 (4.8%) 순으로 나타났다.

Diabetic patients tend to exhibit delayed bone formation and osteoblast differentiation, which results in osteopenia. Recently, numerous clinical reports suggest that 635-nm light irradiation improves bone regeneration and wound healing, and reduces pain in patients suffering from diabetes. The purpose of the present study was to test the hypothesis that 635-nm irradiation can influence bone formation by MC3T3-E1 osteoblasts cultured on high concentrations of glucose(25mmol/L D-glucose) in the presence or absence of phorbol 12-myristate 13-acetate(PMA), and to establish an in vitro pathological model of bone formation. The effect of 635-nm irradiation on bone formation was investigated using Alizarin Red S staining, and alkaline phosphatase enzyme activ ity and calcium deposition assays. In addition, gene expression of the o steogenic markers BMP-2, osterix and osteocalcin were assayed by RT-PCR. Calcium deposition by MC3T3-E1 cells was reduced in the presence of high concentrations of glucose or by PMA supplementation. However, 635-nm irradiation led to an increase in calcium deposition by MC3T3 cells, followed by increased bone mineralization. mRNA expression of BMP-2 and osterix at an early stage and of osteocalcin at a late stage was significantly upregulated by 635-nm irradiation in MC3T3-E1 cells supplemented with high concentrations of glucose. Irradiation at 635 nm increases bone mineralization in MC3T3-E1 cells cultured in vitro on high concentrations of glucose and alters osteogenic gene expression, which accelerates bone formation in hyperglycemic conditions.

본 연구는 전북 무주지역 36년생 리기다소나무 임분을 대상으로 지상부 바이오매스 추정식을 개발하 고, 줄기밀도와 바이오매스 확장계수를 산출하고자 하였다. 리기다소나무의 흉고직경을 독립변수로 하고 바이오매스를 종속변수로 하는 상대생장식을 추정한 결과, 잎 (78%)과 가지 (83%)를 제외하면 모든 부 위에서 결정계수가 95% 이상의 높은 설명력을 나타냈다. 리기다소나무의 바이오매스량은 줄기 목질부 65.9 Mg ha-1, 줄기 수피 9.5 Mg ha-1, 가지 19.6 Mg ha-1, 잎 7.0 Mg ha-1, 전체 102 Mg ha-1로 나 타났으며, 바이오매스 구성비는 줄기목질부 (64.6%) > 가지 (19.2%) > 줄기 수피 (9.3%) > 잎 (6.9%) 순으로 나타났다. 리기다소나무의 줄기밀도 (g/cm3)는 0.453으로 나타났고, 바이오매스 확장계수는 1.344로 나타났다.

본 연구의 목적은 전라북도 고창군 일대의 소나무림을 대상으로 바이오매스 추정식을 개발하고 이를 바 탕으로 바이오매스 및 순생산량, 줄기밀도와 바이오매스 확장계수를 분석하고자 하였다. 유령임분과 성숙 임분의 경우 평균 임령이 각각 10년과 48년으로 나타났으며 임목 전체 건중량은 8.59 kg, 166.66 kg으 로 나타났고 임분밀도를 고려한 단위면적당 지상부 건중량은 17.55 Mg/ha, 122.05 Mg/ha으로 나타났다. 지하부를 포함한 임목전체 건중량은 21.48 Mg/ha, 154.16 Mg/ha으로 나타났다. 부위별 바이오매스 구성 비는 유령임분에서 성숙임분으로 갈수록 줄기목질부, 줄기 수피, 뿌리는 증가하는 경향을 보이는 반면, 잎, 가지 구성비는 감소하는 경향으로 나타났다. 지상부 순생산량은 유령임분에서 6.30 Mg/ha으로 나타 났고 임목 전체에서는 6.95 Mg/ha으로 나타났으며, 성숙 임분에서 11.61 Mg/ha, 임목전체에서 13.19 Mg/ha으로 나타났다. 줄기밀도(g/cm3)는 유령임분과 성숙임분에서 각각 0.338, 0.448로 나타났으며, 임 령이 증가함에 따라 증가하는 일반적인 경향으로 나타났다. 바이오매스 확장계수는 유령임분과 성숙임분 에서 각각 2.304~2.508, 1.318～1.644의 범위로 나타났다.

Human gingival fibroblasts (hGFs) were reported to play an important role in inflammatory reactions to lipopolysaccharide (LPS) from P.gingivalis in the periodontal connective tissue. Although the biostimulatory effects of hyperbaric oxygen therapy, such as anti-inflammatory activity, have been reported, the pathological mechanism is not completely understood. This study examined the changes in the inflammatory cytokine profiles, which are produced after exposure to hyperbaric oxygen in P.gingivalis LPS-treated human gingival fibroblasts, and subsequently to examine the mitogen activated protein kinase (MAPK) pathway involved in cytokine production. Gingival fibroblasts with or without P.gingivalis LPS were exposed to hyperbaric oxygen, and the cytokine profiles in the supernatant were observed using a human inflammation antibody array. The expression of cyclooxyginase-2 (COX-2) protein, phosphorylation of extracellular signal-regulated kinase (ERK1/2), p38, and c-Jun-N-terminal kinase (JNK) MAPK by western blot analysis, and the amount of prostaglandin E2 (PGE2) in the supernatant by an enzyme-linked immunoassay were determined. COX-2 protein expression and PGE2productionwereincreasedsignificantlyintheP. gingivalis LPS-treated group, and were decreased by treating P. gingivalis LPS with hyperbaric oxygen. Treatment of P. gingivalis LPS in the gingival fibroblasts led an increase in the amount of pro-inflammatory-related cytokines interleukin-6 (IL-6) and IL-8 released, whereas hyperbaric oxygen inhibits the irrelease. Ananalysis of the MAPK signal transduction showed that hyperbaric oxygen induced a significant decrease in the level of P38 phosphorylation regardless of the presence or absence of LPS. In addition, hyperbaric oxygen promoted JNK phosphorylation, significantly in the presence of LPS. Hyperbaric oxygen can inhibit pro-inflammatory cytokines and mediate the MAPK signal pathway, and appears to be useful as an anti-inflammatory tool.

본 연구는 2007년도 조사된 국가산림자원조사 자료를 이용하여 충북지방에 분포하는 주요 수종에 대하여 평균 연륜생장량과 연륜생장량에 영향을 미치는 인자들과의 상관관계를 분석하고자 하였다. 충북지역에서 조사된 고정표본점은 총 56개소로 다양한 수종이 분포하였으며 그 중 개체수 분포 비율이 높은 10개 수종에 대하여 총 800본의 연륜생장량이 조사된 목편 자료를 대상으로 분석하였다. 충북지방에서 평균 연륜생장량이 가장 높은 수종은 아까시나무(2.30mm/yr)로 나타났고, 그 다음으로는 졸참나무(2.27mm/yr)>산벚나무(1.98mm/yr)>일본 잎갈나무(1.98mm/yr) 순으로 나타났다. 대부분 주요 수종들의 경우, 영급과 임분밀도가 증가함에 따라 평균 연륜생장량은 감소하는 경향으로 나타났다.

본 연구는 2007년도 국가산림자원조사 자료 중 충청남도 지역에서 조사된 주요 수종별 연년 직경생장량의 특성에 대하여 분석하고자 하였다. 2007년도 충남지역에서 조사된 고정표본점은 총 49개소이며, 직경생장량 조사를 위해 목편을 채취한 개체목으로 총 717본의 표준목이 측정되었다. 주요 수종들의 연년 직경생장량은 임령과 임분밀도가 증가함에 따라 감소하는 일반적인 경향을 보였다. 연년 직경생장량을 분석한 결과에 의하면, 산벚나무가 약 2.14㎜/yr로 연년 직경생장량이 가장 높았고, 그 다음은 졸참나무(2.10㎜/yr), 해송(2.03㎜/yr), 소나무(1.91㎜/yr), 그리고 밤나무(1.90㎜/yr) 순으로 나타났다. 이와 같은 정보는 충남지역에 분포하는 주요 수종의 연년 직경생장량 특성을 이해하는데 중요한 정보를 제공해 준다.