The alfalfa weevil (Hypera postica) is an important pest that causes significant damages to alfalfa crops, reducing yield and quality, but there’s a solution. This research had two main goals to evaluate the efficacy of insecticides available in Korea for alfalfa weevil control and to provide data for pest management studies. The experiment, conducted from 2023 to 2024 at the National Institute of Animal Science in Cheonan, Republic of Korea, included four treatment plots: control (CON), early-occurrence (EAR), mid-occurrence (MID), and late-occurrence (LAT). It also included two frequency plots with primary and secondary insecticide using 50% fenitrothion emulsion, which made it truly comprehensive study. The primary insecticide was applied at the first observation of the alfalfa weevil larvae, with subsequent secondary applications at specified intervals. The results showed that two-times insecticide applications significantly reduced larvae populations and increased yield and nutrient content compared to a single application. Specifically, control rates ranged from 94 to 94.7% on the third day after treatment and from 72.2 to 93.4% on the seventh day. Plots with two applications had higher yields and crude protein content. The study concluded that the timing and frequency of insecticide applications are critical to maximizing alfalfa yield and quality, emphasizing the importance of optimized application strategies for effective pest control.

Considering the various health problems associated with obesity in dogs, including renal diseases, joint disorders, and skin diseases, effective management strategies and guidelines are urgently needed. This situation has led to a growing demand for veterinary medications aimed at addressing obesity in dogs. However, the field faces a significant hurdle due to the absence of standardized guidelines for assessing the effectiveness of these anti-obesity medications in dogs. In response to this gap, the Animal and Plant Quarantine Agency (APQA) in Korea has made a crucial step by introducing clinical trial guidelines to evaluate the efficacy of treatments for canine obesity, specifically aimed at approving veterinary medicinal products. The guidelines outlined the selection criteria for target dogs, highlighting the importance of consistency within the control and treated groups. Treatment efficacy is subsequently evaluated by physical examination, body fat reduction, and biochemical indicators. In addition, the guidelines cover dosage and administration, monitoring after dosing, and statistical analysis. By doing so, this guideline not only highlights the significance of the APQA’s initiative in improving the care of obese dogs but also provides practical insights to enhance the standardization and effectiveness of clinical trials in veterinary medicine.

This study evaluated the immunogenicity of the Bacillus Calmette-Guérin (BCG) vaccine in a guinea pig model to refine preclinical assessment methods. 24 guinea pigs were divided into four groups for immunohistochemical, histopathological, and molecular analyses, including qRT-PCR and ELISA. The ELISA results revealed significant elevations in interleukin 2 (IL-2), interferon-gamma (IFN- ), and tuberculosis-specific antibodies in vaccinated guinea pigs, particularly γ notable after 6 weeks. Although lung cytokine levels remained unchanged, spleen gene expression showed significant differences in interleukin-17, interleukin-12, interleukin-1β, and C-X-C motif chemokine ligand 10 after 6 weeks. Immunohistochemistry revealed peak IL-2 expression at 8 weeks and significant IFN-γ and TNF-α expression at 6 weeks. This study confirmed the effectiveness of BCG vaccine in guinea pigs, providing crucial insights for future tuberculosis vaccine development and standardizing immune response indicators.

This study aims to contribute to resolving the critical issue of weed management in newly established alfalfa fields, study has been conducted on effective herbicide use. The study evaluated the impact of various domestically available foliar herbicides on alfalfa phytotoxicity, weed control, yield, and nutritive value. The experiment was designed in a randomized complete block design with four treatments. Alfalfa ‘SW 5615’ seeded in the spring of 2024 on a 1 ha field (March 18), with herbicide treatments including fluazifop-P-butyl (FPB), bentazone (BEN), and a mixture of these herbicides (MIX). Herbicide efficacy, alfalfa yield, and nutritive value were assessed 30 days post-application. Results indicated that the MIX treatment achieved superior weed control comparable to hand weeding (HW), although it exhibited higher phytotoxicity, requiring extended recovery periods. While MIX led to lower overall yield, it enhanced alfalfa purity, resulting in higher crude protein (CP) content and relative feed value (RFV) compared to other treatments. The study concludes that despite the potential for increased phytotoxicity, mixed herbicide treatments could offer a strategic advantage in enhancing the quality of alfalfa feed through effective weed management, thereby improving CP and RFV, critical factors for the nutritional value of alfalfa. These findings provide valuable insights for optimizing weed management practices in alfalfa cultivation, suggesting that mixed herbicide application, although associated with increased phytotoxicity on the plants, could improve the overall feed quality by reducing weed competition.

본 연구는 웹툰 IP 기반의 게임의 성공과 실폐 사례를 분석하고 안정적인 웹툰의 게임화를 위 해 웹툰 장르별 특성에 맞는 텍스트 기반 게임 유형을 제안한다. 로맨스, 판타지, 액션, 스릴러, 드라마, 코미디 등 다양한 웹툰 장르와 인터랙티브 소설, RPG, 턴제 전투게임, 텍스트 어드벤처 등 게임 장르를 매칭하여 각 장르의 핵심 요소를 게임 메커니즘으로 전환하는 방안을 제시한 다. 또한 텍스트 기반 게임의 장점으로 상상력 자극, 깊이 있는 스토리텔링, 상호작용성 증대 등을 언급하며, 이를 통해 웹툰 IP의 확장과 팬 참여 촉진 가능성을 탐구한다.

현재 존재하는 인공지능 기반 음악 생성에 관한 여러 모델과 연구는 수동 텍스트(Text) 기반 음악 생성에 대해 다루고 있다. 본 논문은 사용자의 편의성을 높이고, 창의적인 음악 생성 과정 을 더욱 원활하게 할 수 있도록 텍스트(TEXT) 프롬프트(Prompt) 자동화를 통한 음악 생성시 스템 방안을 제안한다. 그 방안으로 음원 파일을 통해 수집한 음악 분석 및 데이터화와 가사 정보에서 추출한 키워드를 기반한 장르, 가수, 앨범 등의 정보가 포함된 데이터셋(Dataset)을 구축 후, 파이썬(Python)의 자연어 처리 방법인 Konlpy를 사용하여 가사 데이터를 토큰화하고, TF-IDF(Term Frequency-Inverse Document Frequency) 벡터화를 통해 중요한 단어를 추 출한다. 또한, MFCC, 템포 등의 특징 데이터셋을 통하여 모델을 통한 감정을 예측하고, CNN 모델 및 Chatgpt를 활용한 텍스트 프롬프트를 자동생성하는 방법을 구현하여, MusicGen 모델 을 사용한 자동화 생성 프롬프트 기반 음악을 생성한다. 본 텍스트 프롬프트 자동 생성 화를 통한 음악 생성 연구의 결과는 음악 데이터 분석 및 생성 분야에 기여될 것으로 기대한다.

현대 사회에서 음악은 일상생활에 깊숙이 자리 잡아, 개인의 음악적 취향과 감정 상태에 맞는 콘텐츠를 손쉽게 찾고 소비하는 것이 중요해지고 있다. 콘텐츠 소비 증가와 더불어 제작 속도 및 효율 또한 중요한 요소로 부상하고 있다. 그러나 기존 음악 콘텐츠 제작 방식은 주로 기존 음악을 플레이리스트로 만들고 간단한 애니메이션이나 이미지를 영상으로 추가하는 방식이다. 이러한 한계를 극복하고자, 인공지능(AI) 기술을 활용하여 사용자 맞춤형 음악을 생성하고 콘 텐츠를 제공하는 어플리케이션을 개발하였다. AI 모델을 통해 사용자의 감정 상태를 분석하고, 이를 기반으로 음악적 요소를 최적화하여 개인화된 음악 콘텐츠를 생성하는 것에 목표를 두었 다. Mel-frequency cepstral coefficients(MFCC)와 템포 분석을 통해 음악 데이터의 특징을 추출하고, 이를 기반으로 사용자 감정에 부합하는 프롬프트를 생성하였다. 생성된 프롬프트는 MusicGen 모델에 입력되어, 사용자의 감정 상태와 음악적 취향을 반영한 새로운 음악을 생성 하는 데 활용하였다. 또한, ComfyUI를 활용하여 텍스트-이미지-비디오 변환 파이프라인을 구 축함으로써, 생성된 프롬프트를 기반으로 다양한 멀티미디어 콘텐츠 제작을 가능하게 하였다. 기존 음악 콘텐츠 제작 방식의 시간 및 비용 문제를 해결하고, 사용자에게 보다 정교하고 개 인화된 음악 경험을 제공하는 데 기여할 수 있을 것으로 기대된다. 향후 다양한 분야에서의 응용 가능성을 제시한다.

After the permanent shut down of Kori Unit 1, various decommissioning activities will be implemented, including decontamination, segmentation, waste management, and site restoration. During the decommissioning period, waste management is among the most important activities to ensure that the process proceeds smoothly and within the expected timeframe. Furthermore, the radioactive waste generated during the operation should be sent to a disposal facility to complete the decommissioning project. Square and cylindrical concrete re-package drums were generated during the 1980s and 1990s. The square, containing boron concentrates, and cylindrical, containing spent resin, concrete re-package drums have been stored in a radioactive waste storage building. Homogeneous radioactive waste, including boron concentrates, spent resin, and sludge, should be solidified or packaged in high-integrity containers (HICs). This study investigates the sequential segmentation process for the separation of contaminated and non-contaminated regions, the re-packaging process of segmented or crushed cement-solidified boron concentrate, and re-packaging in HICs. The conceptual design evaluates the re-packaging plan for the segmented and crushed cement-solidified waste using HICs, which is acceptable in a disposal facility, and the quantity of generated HICs from the treatment process.