Lumpy Skin Disease (LSD) and Foot-and-Mouth Disease (FMD) cause substantial economic losses on the livestock industry. Therefore, vaccinations have been implemented as the control strategy in endemic countries. However, the potential adverse effects of administering vaccines for both diseases simultaneously have not been thoroughly evaluated. The aim of this study was to assess the impact of vaccinating dairy cows with either or both LSD and FMD vaccines on milk production and physiological parameters such as milk temperature, rumination time and body weight. The experimental groups were divided into four according to the injection materials: 1) saline, 2) LSD vaccine, 3) FMD vaccine, and 4) both vaccines. The impact of vaccination on milk yield and physiological parameters was evaluated daily until 12 days post-vaccination, and milk components were analyzed twice, once per week. Among the experimental groups as well as each vaccine group, no statistically significant differences (p < 0.05) were observed at milk yield, milk components, or milk temperature. This suggests that simultaneous vaccination of LSD and FMD can be administered without adverse effects.
Additive manufacturing makes it possible to improve the mechanical properties of alloys through segregation engineering of specific alloying elements into the dislocation cell structure. In this study, we investigated the mechanical and microstructural characteristics of CoNi-based medium-entropy alloys (MEAs), including the refractory alloying element Mo with a large atomic radius, manufactured via laser-powder bed fusion (L-PBF). In an analysis of the printability depending on the processing parameters, we achieved a high compressive yield strength up to 653 MPa in L-PBF for (CoNi)85Mo15 MEAs. However, severe residual stress remained at high-angle grain boundaries, and a brittle μ phase was precipitated at Mo-segregated dislocation cells. These resulted in hot-cracking behaviors in (CoNi)85Mo15 MEAs during L-PBF. These findings highlight the need for further research to adjust the Mo content and processing techniques to mitigate cracking behaviors in L-PBF-manufactured (CoNi)85Mo15 MEAs.
This study developed conductive inks composed of carbon black (CB) and silver nanowires (Ag NWs) for cost-effective screen-printing on fabrics. The Ag NW density within the CB matrix was precisely controlled, achieving tunable electrical conductivity with minimal Ag NW usage. The resulting inks were successfully patterned into shapes such as square grids and circles on textile surfaces, demonstrating excellent conductivity and fidelity. Adding 19.9 wt% Ag NWs reduced sheet resistance by ~92% compared to CB-only inks, highlighting the effectiveness and potential of this hybrid approach for cost-effective, high-performance textile-based electronics. The one-dimensional morphology of Ag NWs facilitated the formation of conductive percolation networks, creating efficient electron pathways within the CB matrix even at low loadings. This work advances the field of CB-based conductive inks and provides a scalable and practical method for producing functional, patterned electronic textiles.
This study confirmed the fungal community of rice makgeolli sold in the eastern part of Jeollanam-do using ITS 2 sequence-based metagenome analysis. A total of 18 fungi were found in six makgeolli samples, with Saccharomyces cerevisiae being dominant in all samples at high rates ranging from 96.61~99.96%. The six makgeolli samples were classified into three groups based on the PCoA and UPGMA tree analysis results using the Jaccard distance matrix. Network analysis of the relationships among the 18 identified fungal species helped identify a fungus that demonstrated either a positive or negative correlation with the dominant species, Saccharomyces cerevisiae. This study provides important foundational data for understanding the fungal composition in the makgeolli fermentation process.
Malaria remains a significant public health issue, particularly in regions such as the Korean Demilitarized Zone (DMZ). Effective malaria control and prevention require precise prediction of mosquito density across both monitored and unmonitored areas. This study aimed to develop predictive models to estimate the abundance of malaria vector mosquitoes by integrating meteorological and geographical data. Data from mosquito surveillance sites and NASA MODIS land cover datasets acquired between 2009 and 2022 were utilized. Two predictive models, the Gradient Boosted Model (GBM) and Principal Component Regression (PCR), were employed and evaluated. Model performance was assessed using the coefficient of determination (R²). Results showed that PCR outperformed GBM in predictive accuracy, suggesting that PCR is more robust in handling multicollinearity among variables. However, both models did not show practically-usable level of prediction performance. This study provides a preliminary but foundational framework for extending predictive modeling to broader regions, thereby supporting malaria prevention efforts through improved risk mapping.
장미과의 과일 및 관상용 식물은 세계적으로 경제적, 원예적 가치가 뛰어나다. 장미과의 뱀딸기는 관상 및 약용 작물로써 이용가치가 매우 높은데, 증식방법이 마련되어 있지 않은 실정 이다. 뱀딸기의 종자 종자발아 특성을 조사하기 위해 내부형태 관찰, 수분흡수실험, 온도 별 배양, move-along test, GA3처리 실험을 수행하였다. 뱀딸기 종자는 탈리시점부터 성숙한 배를 지닌다. 수분흡수실험 결과, 침지 3시간만에 종자 무게가 초 기무게 대비 100% 이상 증가하였다. 온도 별 배양 실험 결 과, 25/15, 20/10, 15/6, 5, 25, 20, 15°C에서 각각 8주간 배양하였을 때 88, 71, 61, 12, 89, 39, 17%로 나타났다. Move-along test의 T125/15°C(12주)→20/10°C(4주)→ 15/6°C(4주)→5°C(12주)]에서 12주차까지 72%가 발아하였고 T2[4°C(12주)→15/6°C(4주)→20/10°C(4주)→25/15°C(12주)] 에선 20/10°C까지 발아하지 않았고 25/15°C에 도달하고 나서 발아하여 최종발아율은 16%로 나타났다. GA3처리구에선 배양 3주차에 발아를 시작한 반면에 대조구에선 배양 4주차부터 발 아하였다. 따라서 한반도 자생 뱀딸기 종자는 PD로 분류하였다. 뱀딸기속과 Potentilla속 식물은 서로 근연관계이고, 종간의 종 자휴면에 차이가 나타나 종자휴면 특성에 분화가 일어난 것으로 판단된다.
The development of thermoelectric (TE) materials to replace Bi2Te3 alloys is emerging as a hot issue with the potential for wider practical applications. In particular, layered Zintl-phase materials, which can appropriately control carrier and phonon transport behaviors, are being considered as promising candidates. However, limited data have been reported on the thermoelectric properties of metal-Sb materials that can be transformed into layered materials through the insertion of cations. In this study, we synthesized FeSb and MnSb, which are used as base materials for advanced thermoelectric materials. They were confirmed as single-phase materials by analyzing X-ray diffraction patterns. Based on electrical conductivity, the Seebeck coefficient, and thermal conductivity of both materials characterized as a function of temperature, the zT values of MnSb and FeSb were calculated to be 0.00119 and 0.00026, respectively. These properties provide a fundamental data for developing layered Zintl-phase materials with alkali/alkaline earth metal insertions.
Background: Aflatoxin B1 (AFB1) is a toxic metabolite generated by Aspergillus species and is commonly detected during the processing and storage of food; it is considered a group I carcinogen. The hepatotoxic effects, diseases, and mechanisms induced by AFB1 owing to chronic or acute exposure are well documented; however, there is a lack of research on its effects on the intestine, which is a crucial organ in the digestive process. Dogs are often susceptible to chronic AFB1 exposure owing to lack of variation in their diet, unlike humans, thereby rendering them prone to its effects. Therefore, we investigated the effects of AFB1 on canine small intestinal epithelial primary cells (CSIc). Methods: We treated CSIc with various concentrations of AFB1 (0, 1.25, 2.5, 5, 10, 20, 40, and 80 μM) for 24 h and analyzed cell viability and transepithelial-transendothelial electrical resistance (TEER) value. Additionally, we analyzed the mRNA expression of tight junction-related genes (OCLN, CLDN3, TJP1, and MUC2), antioxidant-related genes (CAT and GPX1), and apoptosis-related genes (BCL2, Bax, and TP53). Results: We found a significant decrease in CSIc viability and TEER values after treatment with AFB1 at concentrations of 20 μM or higher. Quantitative polymerase chain reaction analysis indicated a downregulation of OCLN, CLDN3, and TJP1 in CSIc treated with 20 μM or higher concentrations of AFB1. Additionally, AFB1 treatment downregulated CAT , GPX1, and BCL2. Conclusions: Acute exposure of CSIc to AFB1 induces toxicity, and exposure to AFB1 above a certain threshold compromises the barrier integrity of CSIc.
갯까치수염은 다육성의 2년생 초본 자생식물로서, 제주도, 울릉도를 비롯하여 남해안 지역에서 자라며 자생지의 환경에 맞게 내염성이 크다는 특징이 있고, 다양한 환경에 적응하며 관상가치가 높다. 관련 문헌을 보면 발아조건과 개화조절에 대한 연구만 보고되었고 그 중간단계인 재배에 관한 연구가 부족하여 대량생산을 위한 공정육묘법 개발의 일환으로 이 실 험을 수행하였다. 실험은 플라스틱온실 내에서 발아시킨 1cm 전후의 묘를 50, 128, 200구 트레이에 이식하여 한국원시표 준액(N-P-K-Ca-Mg, 15-3-6-8-4)을 각각 권장 EC농도의 0, 0.5, 1, 2배 농도로 매일 5분간 순환식으로 저면 관수하여 6주간 재배 후 초장, 근장, 엽수, 뿌리수, SPAD, 생체중, 건물 중을 측정하였다. 갯까치수염 생육은 플러그 셀 크기 50셀에 서 생육이 가장 높았다. 양액농도에 따른 갯까치수염의 생육 은 0.5배액에서 초장과 근장의 수치가 가장 높았으며, 모든 생육지표가 양액 농도변화에 따른 차이가 발생하는 것으로 나 타났고 실질적인 총 생산량의 지표라고 할 수 있는 지상부와 지하부의 건물중에 영향을 미치지 않았다는 결과가 나온 것으 로 미뤄 육묘단계에서 양액의 농도가 셀 크기보다 갯까수치염 의 묘 생육에 더 영향이 큰 것으로 보인다. 갯까치수염의 조직 충실도 면에서 0.5, 1, 2배액의 200구에서 가장 높은 결과값 들이 나왔다. 결과적으로 기존 원시표준액에 비해 생장에 유 리한 결과를 보이며 비료도 절약할 수 있는 0.5배 양액처리조 건이 갯까치수염 육묘 재배에 더 효율적이였다.
In order to predict the process window of laser powder bed fusion (LPBF) for printing metallic components, the calculation of volumetric energy density (VED) has been widely calculated for controlling process parameters. However, because it is assumed that the process parameters contribute equally to heat input, the VED still has limitation for predicting the process window of LPBF-processed materials. In this study, an explainable machine learning (xML) approach was adopted to predict and understand the contribution of each process parameter to defect evolution in Ti alloys in the LPBF process. Various ML models were trained, and the Shapley additive explanation method was adopted to quantify the importance of each process parameter. This study can offer effective guidelines for fine-tuning process parameters to fabricate high-quality products using LPBF.
The n-type Bi2-xSbxTe3 compounds have been of great interest due to its potential to achieve a high thermoelectric performance, comparable to that of p-type Bi2-xSbxTe3. However, a comprehensive understanding on the thermoelectric properties remains lacking. Here, we investigate the thermoelectric transport properties and band characteristics of n-type Bi2-xSbxTe3 (x = 0.1 – 1.1) based on experimental and theoretical considerations. We find that the higher power factor at lower Sb content results from the optimized balance between the density of state effective mass and nondegenerate mobility. Additionally, a higher carrier concentration at lower x suppresses bipolar conduction, thereby reducing thermal conductivity at elevated temperatures. Consequently, the highest zT of ~ 0.5 is observed at 450 K for x = 0.1 and, according to the single parabolic band model, it could be further improved by ~70 % through carrier concentration tuning.