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        검색결과 57

        41.
        2010.09 구독 인증기관 무료, 개인회원 유료
        Pluripotency of human embryonic stem cell (hESC) is one of the most valuable ability of hESCs for applying cell therapy field, but also showing side effect, for example teratoma formation. When transplant multipotent stem cell, such as mesnchymal stem cell (MSC) which retains similar differentiation ability, they do not form teratoma in vivo, but there exist limitation of cellular source supply. Accordingly, differentiation of hESC into MSC will be promising cellular source with strong points of both hESC and MSC line. In this study, we described the derivation of MSC like cell population from feeder free cultured hESC (hESC- MSC) using direct differentiation system. Cells population, hESC-MSC and bone marrow derived MSC (BM-MSC) retained similar characteristics in vitro, such as morphology, MSC specific marker expression and differentiation capacity. At the point of differentiation of both cell populations, differentiation rate was slower in hESC-MSC than BM-MSC. As these reason, to verify differentially expressed molecular condition of both cell population which bring out different differentiation rate, we compare the molecular condition of hESC-MSC and BM-MSC using 2-D proteomic analysis tool. In the proteomic analysis, we identified 49 differentially expressed proteins in hESC-MSC and BM-MSC, and they involved in different biological process such as positive regulation of molecular function, biological process, cellular metabolic process, nitrogen compound metabolic process, macromolecule metabolic process, metabolic process, molecular function, and positive regulation of molecular function and regulation of ubiquitin protein ligase activity during mitotic cell cycle, cellular response to stress, and RNA localization. As the related function of differentially expressed proteins, we sought to these proteins were key regulators which contribute to their differentiation rate, developmental process and cell proliferation. Our results suggest that the expressions of these proteins between the hESC-MSC and BM-MSC, could give to us further evidence for hESC differentiation into the mesenchymal stem cell is associated with a differentiation factor. As the initial step to understand fundamental difference of hESC-MSC and BM-MSC, we sought to investigate different protein expression profile. And the grafting of hESC differentiation into MSC and their comparative proteomic analysis will be positively contribute to cell therapy without cellular source limitation, also with exact background of their molecular condition.
        4,000원
        43.
        2008.05 KCI 등재 구독 인증기관 무료, 개인회원 유료
        This study was performed to estimate biomass and to provide management plan through population ecological characteristics, including growth parameters, survival rate, instantaneous coefficient of natural and fishing mortalities, and age at first capture of hen clam, Mactra chinensis, in the Dong-li self-regulatory community of Busan. The von Bertalanffy growth parameters estimated from a non-linear regression were SH∞=86.24mm, K=0.12/year, and = -1.37year. Survival rate(s) of the hen clam was 0.515. The instantaneous coefficients of natural mortality(M) was estimated to be 0.232/year and fishing mortality(F) 0.432/year for hen clam. The current biomass of the hen clam in the study area was estimated to be 713mt and the acceptable biological catch(ABC) was estimated under various harvest strategies based on F0.1 and F40%.
        4,300원
        44.
        2006.12 KCI 등재 구독 인증기관 무료, 개인회원 유료
        목적 : 본 연구는 임상적 활용을 위하여 LOTCA-G 번역판을 사용하여 도시지역 노인의 인지기능을 알아보고, LOTCA-G 한국판 개발을 위한 기초자료를 확보하고자 시행되었다. 연구방법 : 연구대상자는 대전광역시에 거주하는 뇌손상의 경험이 없거나 치매로 진단받지 않은 65세 이상의 노인 117명이었으며 직접 면접조사 및 LOTCA-G를 사용한 인지기능평가를 통해 자료를 수집하였다. 자료 수집 기간은 2005년 3월 11일에서 4월 2일까지로 23일간 실시되었다. 결과 : 1. 연구대상자들의 LOTCA-G를 이용한 인지기능 검사 점수는 총점 104점에 평균 92.17±10.66점이었으며, 연령이 낮은 군일수록, 교육수준이 높은 군일수록 인지기능점수가 통계적으로 유의하게 높았다.2. LOTCA-G의 각 하위영역별 평가 점수는 교육수준이 높은 군인 경우에 대부분의 영역에서 유의하게 높았고, 연령이 높은 군일수록 각 영역 별로 점수가 통계적으로 유의하게 낮아졌다.3. LOTCA-G의 각 하위영역 간 관계는 실행력과 주의력/집중력을 제외하고는 모든 영역 간에 유의한 상관관계를 보였다.4. MMSE-K와 LOTCA-G의 총점수를 비교했을 때 유의한 높은 상관관계를 가짐을 알 수 있었으며, MMSE-K의 분류별 점수에 따른 LOTCA-G의 점수는 24점 이상(96.35±5.52), 23-18점(87.72±5.52), 17점(55.40±16.56)으로 각 각 유의한 차이가 있었다. 결론 : LOTCA-G를 사용한 도시지역 노인의 인지기능수준은 연령, 교육기간에 따라 차이가 있었다. 간이신경검사인 MMSE-K와 비교하였을 때 LOTCA-G는 유의미한 상관관계를 가지고 있어 연구에서 사용된 한국어로 번안된 본 도구도 인지기능을 평가하는 데 타당함을 알 수 있었다. 그러나 외국에서 개발된 LOTCA-G를 그대로 번안 하여 사용한 것이므로 문화적, 사회적 차이로 인한 문항 간 차이점이 존재하는 것으로 사료된다. 후속 연구에서는 이러한 점을 수정 및 보완하여 한국판 LOTCA-G를 개발하는 것이 필요하겠다.
        4,500원
        47.
        2000.10 KCI 등재 구독 인증기관 무료, 개인회원 유료
        The purpose of this study was to obtain normative data and comparing cognitive abilities of patients with stroke and normal population by administering Lowenstein Occupational Therapy Cognitive Assessment (LOTCA). The subjects were 31 patients with stroke and 19 adults in a good health. The results were as follows: 1. The experimental group received statistically lower scores than the control group in all items except for object identification, shape identification and copying geometric forms. 2. There was no significant difference in analysis of items based on affected side. 3. There was a significant difference in the relationship between educational background and visuomotor organization and thinking operation. 4. There was a significant difference in the relationship between treatment period and visuomotor organization. 5. There was no significant difference in the relationship between LOTCA scores and age and onset of the disease. The result shows that there was a significant difference in LOTCA scores between the experimental group and control group. These data are expected to be used as a baseline.
        4,000원
        51.
        1997.06 KCI 등재 SCOPUS 구독 인증기관 무료, 개인회원 유료
        Near infrared JHK magnitudes are presented for two hundred two high proper motion stars. We have observed high proper motion stars in the near-infrared bands(JHK) using the COB detector on the Kitt Peak 1.3m, 2.1m and 4m telescopes. The observations and data reduction procedures are described. The infrared color magnitude diagram and color-color diagrams for the program stars are presented.
        4,200원
        52.
        2015.12 KCI 등재 서비스 종료(열람 제한)
        The purpose of this study is to investigate how the hollowization in rural villages which causes marginal villages appears in Korean rural villages and whether the hollowization has relation with decrease and aging of population or not. For achieving the research objective, survey was carried out focused on Geumsan-gun. As a result, it confirmed that rural out-migration and rural decline especially in 'people', 'land(economic situation)' and 'community' have being progressed. Also variance analysis and regression analysis were executed with using the number of population and the ratio of people over 65 as dependent variables and using each survey contents(variables) as independent variables. The results of analysis showed that the ratio of people over 65(+), the income level per household(-), the rate of fallow lands(+), the number of empty houses(+), programs for urban-rural interchange(+), and the implementing public projects(+), etc. have a relation with the number of population(-) and the number of population(-), the income level per household(-), the rate of fallow lands(+), the number of empty houses(+), activities of communities(+), and the implementing public projects(+), etc. have a relation with the ratio of people over 65(+) (+: increase, -: decrease). So the hollowization in people', 'land(economic situation)' and 'community' has direct relation with decrease and aging of population in rural areas.
        54.
        2011.03 KCI 등재 서비스 종료(열람 제한)
        본 연구에서는 ARIMA(Autoregressive Integrated Moving Average) 모델을 이용하여 농촌관광마을의 월별 관광객을 추정하였다. 단일 마을에 대한 시계열 자료를 경상북도 안동시에 위치한 하회마을을 대상으로 구축하였다. 월별 시계열 자료는 2000년부터 2010년까지 구성되었는데(2008년도 누락), 2000년에서 2007년까지 자료는 최적 모델의 도출에 나머지는 예측치의 검정에 사용되었다. 연구 결과 최적모델에 필요한 시계열 자료의 길이는 6년으로 나타났으며, 최적모델은 계절성을 고려한 SARIMA(2,1,1)(1,1,2)12로 나타났다. 최적 시계열 년수로 나타난 6년을 사용하여 2000-2005, 2001-2006, 그리고 2002-2007의 자료로부터 각각 SARIMA(2,1,1)(1,1,2)12를 도출하여, 차기년도들에 대한 예측결과를 비교한 결과, 높은 R2값을 보였다.
        55.
        2008.08 KCI 등재 서비스 종료(열람 제한)
        Settlement problems in rural area are gradually becoming more intense due to decreasing agricultural income led by market globalization. Rural tourism is considered as one of alternatives for complementing agricultural income. In this study, we analyzed the relation of rural development project and the influx of population on green tourism villages. Results show that the influx of population in rural area is related with project cost, tourism income, visiting numbers, and ratio of labor population. With these results, we modified rural population model for estimating future rural population. Adapted result to Buraemi village by modified model showed that estimation error can be decreased from 7.23% to 0.95%.
        57.
        2003.05 KCI 등재 서비스 종료(열람 제한)
        The purpose of this study is to analyze the impact of land-use and population change in rural area by new expressway. Chungbu expressway constructed in 1987, going through the south area of Kyunggi province from Seoul, was selected as a case expressway, and also 2 cities and 18 subdivisions of county in its surrounding area, as a case study area. To analyze the change characteristics before and after the construction, land-use maps of 1986 and 1996 were collected, including the census data for the years in cities and counties yearbooks. Remote sensing technology was applied to classify the land-use maps with six types of land use. Geographic information system was also used for spatial analysis, such as the land-use and accessibility changes. A 5 km buffer zone from interchange of the expressway showed about two times increase of urbanized built-up area than a 5 km buffer zone from the expressway. Accessibility from Seoul and cities was improved in most areas, which is accessing to Seoul through existing Youngdong expressway. Ten rural areas showed increased population with accessibility of average 52 minutes to Seoul and 19 minutes to cities, while eight areas showed decreased population with average 73 minutes to Seoul and 35 minutes to cities. This shows that the threshold value, which is time distance to Seoul and cities for population increase or decrease, one and half hours, respectively. Urbanized area was increased in most areas, even in population decrease areas, so this indicates that there are thinning rural areas, increasing urbanized area while decreasing population.
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