Background: Knee osteoarthritis (OA) causes not only pain during walking but also walking disorders. Therefore, intervention for older patients with OA is important. Objective: To study investigated the effects of kinesio taping (KT) on pain and walking ability in elderly persons with knee OA. Design: One group, pre-post design Methods: This study enrolled 12 community-dwelling elderly people with knee OA. KT was applied on the surrounding structures, including the patellar and bilateral lateral ligaments. Assessment was made using the visual analog scale and GAITRite system to measure pain and walking ability during KT and non- KT conditions. Results: In this study, compared to the non-KT condition, the KT condition showed a significant improvement in walking ability and pain reduction during walking (velocity, cadence, step length, and stride length) (p < 0.05). Conclusion: This study demonstrated that knee KT has a positive effect on pain reduction and walking ability of the elderly with OA.

Purpose: Breast cancer survivors(BCS) have memory, attention, processing speed, and/or executive function impairment affecting their quality of life(QOL) and function. Study aims were: (1) compare computer-assisted cognitive training with visual exercises to one with audio+ visual exercises, and (2) gain insight into the relationship between engagement in meaningful activities, cognitive deficits and QOL. Methods: This pilot study used an experimental design with 24 women. Pre and post measures assessed working memory, perceived cognition, QOL and engagement in meaningful activities. Results: Treatment effects were not significant for working memory or engagement in meaningful activities. Visual group participants scored significantly better on perceived cognitive function posttest test(M = 91.62, SD = 21.75) than pretest(M = 74.48, SD = 29.00), p = .010 and significantly higher on QOL posttest(M = 6.42, SD = 1.27) than pretest(M = 5.60, SD = 1.76), p = .004. Pretest perceived cognitive function was significantly associated with pretest(ρ = .617, p < .001) and posttest(ρ = .436, p < .05) QOL. Conclusion: Computer-assisted cognitive training with visual exercises appears to improve perceived cognitive function and QOL for BCS. A positive relationship exists between perceived cognitive function and QOL.

목적 : 본 연구는 지역사회 거주 고령자의 건강과 삶의 질에 영향을 미치는 다면적 라이프스타일을 측정할 수 있는 라이프스타일 프로파일 개발을 위하여 구성요소를 도출 하고자 하였다. 연구 방법 : 2019년 1월부터 2019년 2월까지 노인과 라이프스타일에 관련된 전문가 패널 13명에게 델파 이 기법을 사용하여 의견을 수렴하였다. 본 연구는 총 3차에 걸쳐 설문조사를 수행하였다. 1차 델파이 설문에는 문헌고찰을 근거로 라이프스타일에 대한 정의와 노인의 다면적 라이프스타일을 측정하기 위한 구성요소에 대해 개방형과 폐쇄형 질문을 혼합하여 전문가의 의견을 수렴하였다. 2차 델파이 조사에서는 1차 설문 결과를 반영하여 중복 항목 삭제, 수정 및 재구조화 하였다. 3차 델파이 조사는 2차 설문조사의 응답을 전문가 패널에게 제시한 후 전문가의 의견을 최종 수렴하였다. 결과 : 1차 델파이 결과에서 노인의 다면적 라이프스타일 프로파일 관련 항목으로 총 66개의 항목이 도출되었다. 이후 연구 저자들의 중복 항목 삭제, 수정 및 보완을 거쳐 총 27개의 항목이 도출되었다. 2차 델파이 결과는 내용 타당도 비율 .54를 이하의 값을 보인 5개의 항목 중 연구자 간의 합의에 따라 3개 의 항목만을 삭제하여 총 24개의 항목이 도출되었다. 최종 3차 델파이에서는 총 3항목이 내용 타당도 비율 .54 이하로 선정되었으나, 문헌고찰과 연구자 간의 합의에 근거하여, 최종적으로 24개의 항목을 선 정하였다. 델파이 결과의 평균 내용 타당도 비율은 .83, 안정도는 .14, 수렴도는 .18, 합의도는 .88로 높 게 분석되었다. 결론 : 본 연구를 통해 노인의 다면적 라이프스타일을 측정할 수 있는 항목들을 개발하였으며, 관련 평가 항목의 내용 타당도를 검증하였다. 향후 노인의 다면적 프로파일 개발을 위한 기초자료로 활용되기를 기대한다.

Background: Visual and somatosensory integration processing is needed to reduce pusher behavior (PB) and improve postural control in hemiplegic patients with acute stroke. Objects: This study aimed to investigate the effects of game-based postural vertical training (GPVT) on PB, postural control, and activity daily living (ADL) in acute stroke patients. Methods: Fourteen participants with acute stroke (<2 months post-stroke) who had PB according to the Burke lateropulsion scale (BLS) (score>2) were randomly divided into the GPVT group (n1=7) and conventional postural vertical training (CPVT) group (n2=7). The GPVT group performed game-based postural vertical training using a whole-body tilt apparatus. while the CPVT group performed conventional postural vertical training to reduce PB (30 minutes/session, 2 times/day, 5 days/week for 3 consecutive weeks). The BLS was evaluated to assess the severity of PB. And each subject’s postural control ability and ADL level were assessed using the postural assessment scale for stroke (PASS), balance posture ratio (BPR), and Korean-modified Barthel index (K-MBI). Outcomes were measured preand post-intervention. Results: Comparison of the pre- and post-intervention assessment results showed that both interventions led to the following significant changes: decreased severity of PB scores and increased PASS, BPR, and K-MBI scores (p<.05). In particular, statistical analysis between the two groups, the BLS score was significantly decreased in the GPVT group (p<.05). And PASS, BPR, and K-MBI scores were significantly improved in the GPVT group than in the CPVT group (p<.01, respectively). Conclusion: This study demonstrated that GPVT lessened PB severity and improved postural control ability and ADL levels in acute stroke patients.

Background: Aging reduces cognitive abilities, including visual memory (VM) and visual discrimination (VD). Since common cortical networks subserve eye movement and attention, voluntary eye movement may improve visual attention. Visual selective attention was major role for memory, and visual memory and visual attention are intimately related. Objective: To identify the improvement in VD and VM, after implementing the eye movement program consisting of saccadic eye movement (SEM) and pursuit eye movement (PEM) in the institutionalized healthy elderly. Design: Randomized controlled trial. Methods: The study involved a sample of 36 participants, and the mean age was 79.03 years (range 76~84 years). They were randomly allocated to the experimental group (n=16) and control group (n=20). Participants in the experimental group performed SEM 5 times per week for 4 weeks: twice daily at the same time in the morning and afternoon. The program was carried out for 3 minutes, and it consisted of SEM and PEM. The target’s moving frequency was set at 0.5 Hz. VM and VD at the baseline and post-intervention were measured using Motor-Free Visual Perception test-4 (MFVPT-4). Results: VM significantly improved in the experimental group (p < .01), and significant differences were observed compared to the control group (p < .01). There was no significant change in VD. Conclusion: The eye movement program consisting of SEM and PEM increased VM more than VD. Therefore, eye movement program was feasible interventions for improving VM in institutionalized elderly persons.

This study deals with the microstructure and tensile properties of 600 MPa-grade seismic reinforced steel bars fabricated by a pilot plant. The steel bar specimens are composed of a fully ferrite-pearlite structure because they were air-cooled after hot-rolling. The volume fraction and interlamellar spacing of the pearlite and the ferrite grain size decrease from the center region to the surface region because the surface region is more rapidly cooled than the center region. The A steel bar specimenwith a relatively high carbon content generally has a higher pearlite volume fraction and interlamellar spacing of pearlite and a finer ferrite grain size because increasing the carbon content promotes the formation of pearlite. As a result, the A steel bar specimen has a higher hardness than the B steel bar in all the regions. The hardness shows a tendency to decrease from the center region to the surface region due to the decreased pearlite volume fraction. On the other hand, the tensile-to-yield strength ratio and the tensile strength of the A steel bar specimen are higher than those of the B steel bar with a relatively low carbon content because a higher pearlite volume fraction enhances work hardening. In addition, the B steel bar specimen has higher uniform and total elongations because a lower pearlite volume fraction facilitates plastic deformation caused by dislocation slip.

A pilot-scale biocover was installed at a sanitary landfill for municipal waste, and the removal of volatile organic compounds (VOCs) by the biocover was evaluated for a long period of 550 days. The biocover (2.5 m W × 5 m L × 1 m H) was constructed with the mixture of soil, perlite, earthworm cast and compost (6:2:1:1, v/v). The total VOCs concentration of the inlet gas into the biocover was 820.3 ppb~7,217.9 ppb, and the total VOCs concentration of the outlet gas from the surface of the biocover was 12.6 ppb~1,270.1 ppb. The average removal efficiency of total VOCs was 87.6 ± 11.0% (60.5% for minimum and 98.5% for maximum). Toluene concentration was the highest among the inlet VOCs, followed by ethylbenzene, m, p-xylene and o-xylene. These aromatic VOCs accounted for more than 50% of the total VOCs concentration. Other than these aromatic VOCs, hexane, cyclohexane, heptane, benzene, and acetone were major VOCs among the inlet VOCs. Compared with the VOC profiles in the inlet gas, the relative contribution of dichloromethane to the outlet VOCs emitted from the biocover layer increased from 0.1% to 15.3%. The average removal efficiencies of BTEX in the biocover were over 84% during the operation period of 550 days. The average removal efficiencies of hexane, cyclohexane and heptane in the biocover were 86.0 ± 18.9%, 85.4 ± 20.4% and 97.1 ± 4.0%, respectively. The removal efficiency of VOCs in the biocover decreased not only when the ambient temperature had fallen below 5oC, but also when the ambient temperature had risen above 23oC. Information on the VOCs removal characteristics of the biocover installed in the landfill field can be useful for commercializing the biocover technology for the treatment of VOCs.

The purpose of this study was to investigate the short-term effects of lumbar rotational mobilization under the single-leg standing (SLS) position. Fifteen healthy individuals were recruited, and randomized to agroup of trunk rotational exercise (TRE) and lumbar rotational mobilization (LRM). Trunk twist rotational exercise was performed to the TRE group, and mobilization was applied to the LRM group on the lumbar spine. Velocity of the center of pressure (VCOP) and center of pressure (COP) for each participant were measured through SLS. COPs were not significantly increased or decreased after treatment in both groups. VCOPs also did not change considerably except on the right side when the eye was closed. There was no significant difference between COPs and VCOPs in two groups. This study suggests that trunk rotation exercise and lumbar rotation mobilization would have similar effects on balance ability.

Exosomes are Nano-sized lipid vesicles secreted from mammalian cells containing diverse cellular materials such as proteins, lipids, and nucleotides. Multiple lines of evidence indicate that in saliva, exosomes and their contents such as microRNAs (miRNAs) mediate numerous cellular responses upon delivery to recipient cells. The objective of this study was to characterize the different expression profile of exosomal miRNAs in saliva samples, periodically isolated from a single periodontitis patient. Unstimulated saliva was collected from a single patient over time periods for managing periodontitis. MicroRNAs extracted from each phase were investigated for the expression of exosomal miRNAs. Salivary exosomal miRNAs were analyzed using Affymetrix miRNA arrays and prediction of target genes and pathways for its different expression performed using DIANA-mirPath, a web-based, computational tool. Following the delivery of miRNA mimics (hsa-miR-4487, -4532, and -7108-5p) into human gingival fibroblasts, the expression of pro-inflammatory cytokines and activation of the MAPK pathway were evaluated through RT-PCR and western blotting. In each phase, 13 and 43 miRNAs were found to be differently expressed (|FC| ≥ 2). Among these, hsa-miR-4487 (|FC|=9.292005) and hasmiR- 4532 (|FC|=18.322697) were highly up-regulated in the clinically severe phase, whereas hsa-miR-7108-5p (|FC|= 12.20601) was strongly up-regulated in the clinically mild phase. In addition, the overexpression of miRNA mimics in human gingival fibroblasts resulted in a significant induction of IL-6 mRNA expression and p38 phosphorylation. The findings of this study established alterations in salivary exosomal miRNAs which are dependent on the severity of periodontitis and may act as potential candidates for the treatment of oral inflammatory diseases.

Pilot Aptitude Research Equipment (PARE) is a simulator developed to measure or research pilot aptitude and train for student pilots. Design of an ergonomic PARE operation console is required to operate the equipment effectively. This study carried out five steps : (S1) operator questionnaire survey, (S2) anthropometric design formula development, (S3) usability evaluation, (S4) improvement design, and (S5) validation considering both Physical User Interface (PUI) and Graphic User Interface (GUI) of PARE operation console. The operator questionnaire surveyed needs for each PUI and GUI part of the console from two PARE actual operators. In terms of PUI, the anthropometric design formula was developed by using design variables, body dimensions, target population characteristics, and reference posture related to the PARE console. In terms of GUI, the usability evaluation was conducted by three usability testing experts with a 7-point scale (1 : very low, 4 : neutral, 7 : very high) on GUI of the PARE operation console by seven usability criteria. The improved PARE operation console was designed to reflect the optimal values of design variables calculated from design formula, the results from usability testing, and the operator’s needs. The improvement effect was observed by 20 people who had experience with the PARE operation console. As a result of the validation, monitor visibility and cockpit visibility for the improved PUI design and visibility and efficiency for the improved GUI design were significantly increased by more than 90% respectively. The improved design of the PARE operation console in this study can contribute to enhance operation performance of the PARE.

호소수에 대한 막여과 공정 설계 및 운영인자를 도출하기 위하여 부산시 소재 회동 수원지의 물을 원수로 하는 200 m3/일 용량의 정수처리 침지식 막여과 pilot을 운영하였다 (운영기간 : 2018년 1월 ~ 9월). 막여과 공정 운영 관점에서 주요한 원수 수질변화로는 1월 ~ 2월 사이 수온이 5 ℃ 이하를 유지하였고, 6~7월의 평균 탁도는 24±40 NTU 이었으며, 7월 중 태풍 발생으로 인하여 약 229 NTU의 고탁도가 유입되었다. 막여과 pilot 운영결과를 바탕으로 막여과 공정의 주요 설계값인 막여과 유속, 막여과 차압, 약품 세척 주기 및 단위공정의 운전순서를 결정하였다. 운영결과 중에서 특별히 괄목할 만한 관찰점은 막여과 배출수 탁도의 중력침전 제거율이 평균 94±4%로 분석된 것이다.