식용곤충인 갈색거저리 유충이 식품 대체원료로써 식육에 대한 대체 가능성을 타진하고자 갈색거저리 유충 분말을 대체하지 않은 제품을 대조구로 설정하고 1%, 2%, 3% 비율로 대체한 유화소시지를 처리구로 하여 4±1℃에서 1, 8, 15, 22, 29일간 저장하면서 이화학적 특성과 관능적 특성 변화를 측정하였다. 갈색거저리 유충 분말을 첨가한 처리구의 pH는 대조구보다 증가하였고, 보수성(WHC)은 저장기간에 따라 대조구와 처리구 간 유의적인 차이는 크게 나타나지 않았으나, 대체량이 많을수록 보수성이 더 우수하였다(p<0.05). 휘발성 염기태질소(VBN), 지방산패도(TBARS) 는 대조구보다 감소하였으며, 관능검사의 경우 대조구와 유의적 차이가 나타나지 않았다(p<0.05). 따라서, 처리구가 대조구보다 우수한 품질과 저장성을 가지고 있었으며, 기호적인 측면에서도 뒤처지지 않아서 갈색거저리 유충 분말로 식육을 대체하는 것이 가능하다고 판단되어 식용곤충을 식품 대체원료로 제품화하였을 때, 식용곤충에 대한 거부감을 완화하고 소비자들에게 있어 긍정적인 인식의 변화를 이끌어낼 수 있는 기초자료를 제시할 수 있었다.

This study aimed to develop a solid self-nanoemulsifying drug delivery system (solid-SNEDDS) to enhance the formulation of ketoconazole (KTZ), a BCS Class II drug with poor solubility. Ketoconazole, which is insoluble above pH 3, requires solubilization for effective delivery. This SNEDDS comprises oil, surfactant, and co-surfactant, which spontaneously emulsify in the gastrointestinal tract environment to form nanoemulsions with droplet sizes less than 100 nm. The optimal SNE-vehicle composition of oleic acid, TPGS, and PEG 400 at a 10:80:10 weight ratio was determined based on the smallest droplet size achieved. This composition was used to prepare liquid SNEDDS containing ketoconazole. The droplet size and polydispersity index (PDI) of the resulting liquid SNEDDS were analyzed. Subsequently, solid-SNEDDS was fabricated using a spray-drying method with solidifying carriers such as silicon dioxide, crospovidone, and magnesium alumetasilicate. The physicochemical properties of the solid-SNEDDS were characterized by scanning electron microscopy and powder X-ray diffraction, and its solubility, droplet size, and PDI were evaluated. In particular, the solid-SNEDDS containing ketoconazole and crospovidone in a 2:1 weight ratio exhibited significantly enhanced solubility, highlighting its potential for improved medication adherence and dissolution rates.

PURPOSES : This research assesses the influence of emulsified asphalt on vegetation growth by examining parameters such as moisture content, temperature, pH, electrical conductivity, and analyzing the extent of green coverage using image analysis. METHODS : Within this study, sensors were employed to measure the growth environment of vegetation treated with emulsified asphalt. Furthermore, the analysis of the greening rate through image analysis has been incorporated. RESULTS : Research indicates that emulsified asphalt effectively secures seeds to surfaces and maintains moisture content for an extended period. However, the excessive utilization of emulsified asphalt has been observed to reduce germination and greening rates. CONCLUSIONS : The application of an optimal emulsified asphalt content is presumed to promote vegetation growth. To establish objective, it is imperative to conduct comprehensive research on its long-term structural effects regarding growth, greening rate, and slope when integrated with emulsified asphalt.

This study aims to prepare a colloidal silica-containing powder to enhance the solubility and dissolution rate of rivaroxaban using a self-nanoemulsifying drug delivery system (SNEDDS). We investigate the impact of colloidal silica on a nanoemulsion system for preparing powdered SNEDDS. The liquid SNEDDS comprises 30/20/50 (w/w/w) Peceol/ Cremophor RH40/Tween 80, which results in the formation of the smallest droplets. Three powdered SNEDDS formulations are prepared by suspending the liquid SNEDDS formulation using colloidal silica and spray drying. The powdered SNEDDS prepared with liquid SNEDDS and colloidal silica at a ratio of 1/0.5 (w/w) exhibits the highest water solubility (0.94 ± 0.62 vs. 26.70 ± 1.81 μg/mL) and dissolution rate (38.4 ± 3.6 vs. 85.5 ± 3.4%, 45 min) when compared to the drug alone. Morphologically, the liquid SNEDDS is adsorbed onto colloidal silica and forms smaller particles. In conclusion, an SNEDDS containing rivaroxaban, prepared using colloidal silica, facilitates the creation of a nanoemulsion and enhances the water solubility of rivaroxaban. Accordingly, this technology holds significant potential for commercialization.

유화 질감은 예술적 표현력을 가진 회화 기법으로 창작자의 고유한 이념과 감정을 표현해내는 주요한 수단이다. 이러한 유 화 질감의 응용을 통해 현대 유화에는 보다 다양한 회화 기법 의 표현이 가능해졌고, 현대 유화의 창작공간과 구상범위가 확 대되었으며, 이는 창작자의 아이디어 혁신을 촉진했다. 유화 질감은 모두 창작자의 고도로 숙련된 표현기술이 반영 되며 동시에 다양한 심리 상태와 정신세계를 드러낼 수 있다. 또한 예술가가 상상한 이미지를 유화 질감을 통하여 창작에 응 용할 때 작품에 대한 인지적 감상 방식이 피동적 감상에서 자발 적이고 능동적인 참여로 전환되며 이러한 참여는 감정적인 특징 을 가진다. 본 연구는 먼저 이형사신의 개념 및 발전과정을 알아보고, 유화 질감의 표현방법을 실제 회화 사례와 결합하여 분석한 후 작가의 감정을 전달할 수 있는 주요한 유화 질감 표현의 세 가 지 방법인 추상적 질감, 구상적 질감, 의상적 질감을 고찰하고 자 한다. 그리고 유화 질감의 표현 방법을 통해 그림 속에 이 형사신이 어떻게 실현되었는지 논의하고자 한다.

The objective of this study is to assess the impact of spray drying conditions on medium-chain triglyceride (MCT) loading, solubility, and release of an MCT-loaded solid self-emulsifying system in a water-insoluble oily substance. MCT-loaded solid self-emulsifying systems are prepared by spray drying with SDS and calcium silicate. The effects of inlet temperature (60, 80, or 100oC) and feed solution composition (0, 10, 50, 90, or 100% ethanol) on physicochemical properties of MCT-loaded solid self-emulsifying systems are studied. The inlet temperature significantly affects the water solubility of MCT. Moreover, the feed solution composition significantly affects water solubility, release rate, and MCT loading. The MCT-loaded solid self-emulsifying system obtained at 60oC using 90% ethanol feed solution shows the best physicochemical properties among the synthesized products and exhibits better water solubility (4.43 ± 0.44 vs. 0 μg/mL) and release (94.4 ± 1.6 vs. 32.8 ± 7.4%, 60 min) than a commercial product. Furthermore, the MCT-loaded solid self-emulsifying system shows an excellent emulsion droplet size (approximately 230 nm).

This study investigated the quality characteristics of emulsion-type chicken breast sausages containing black soldier fly larvae (BSFL) powder. The chicken breast and BSFL powder were added at various mixing ratios (C:chicken breast 56% and BSFL powder 0%, 1%:chicken breast 55% and BSFL powder 1%, 2%:chicken breast 54% and BSFL powder 2%, 3%:chicken breast 53% and BSFL powder 3%). The pH, moisture content, and water holding capacity of the sausages increased with the powder amount. In the instrumental color evaluation, the L* and b* values were significantly different among the samples (p<0.05). However, there was no significant difference in a* value (P>0.05) with the amount of powder added. Volatile basic nitrogen and acid value tended to increase with the amount of BSFL powder. The total phenolic content tended to increase, but the value of IC50 according to DPPH radical scavenging decreased as the amount of powder increased. This study concluded that BSFL powder can be used in meat products processing as a substitute for meat protein and may also improve antioxidant activity.

본 연구는 기능성 물질인 알로에를 종류별로 첨가함에 따라 유화소시지의 이화학적 특성과 저장성, 그리고 관능성에 미치는 영향을 조사하기 위해 수행되었다. 알로에 베라(AV구)와 알로에 사포나리아(AS구)는 각 3%씩 첨가하였으며, 모든 처리구들은 냉장온도 4±1℃에서 4주간 저장하면서 주 1회 간격으로 실험이 진행되었다. pH는 AV구와 AS구가 대조구보다 유의적(p<0.05)으로 낮았고, 저장기간의 경과함에 따라 대조구 및 모든 처리구는 증가하였다. 보수성에서 AS구는 대조구와 AV구보다 유의적(p<0.05)으로 높은 값을 나타냈으며, 저장기간의 경과함에 따라 대조구 및 모든 처리구는 유의적(p<0.05)으로 감소하였다. 적색도는 AS구가 대조구 및 AV구 보다 낮은 값을 나타내었고, 황색도는 AS구가 대조구, AV구보다 높은 값을 나타내었다. 전단가는 AS구가 대조구보다 낮은 값을 나타냈으며, AV구와는 유의적인 차이가 없었다. 지방 산패도에서 AS구는 유의적 (p<0.05)으로 가장 낮은 값을 나타내었고, 관능 평가의 색은 AV구가 가장 높은 값을 나타냈으며, 선호도는 AV구가 대조구보다 높은 값을 나타냈고 AS구와는 유의적인 차이가 없었다. 이는 알로에 사포나리아의 첨가가 높은 보수성, 알로에 베라 첨가보다 낮은 지방산패도, 유사한 관능성을 나타내 기능성 소시지의 개발에 충분한 경쟁력을 가지고 있으며 향후 알로에 사포나리아를 첨가한 육제품의 일반화 및 대량생산 체계의 확립에 긍정적인 영향을 준다고 판단된다.

Curcumin is not soluble in water. Therefore, curcumin emulsion that can dissolve well in water were prepared using multi-emulsification technology, and the antioxidant activities and physical properties of emulsion were measured. Although curcumin was not dissolved in water, it was confirmed to be well dispersed in water when prepared in an aqueous dispersion curcumin emulsion. After dissolving curcumin using water and ethanol as solvents, respectively, the DPPH and ABTS radical scavenging abilities of the filtrate and the curcumin emulsion were measured. Because it was not dissolved in water, activities were not shown. However, when curcumin was dissolved in ethanol, the activities increased as the concentration of curcumin increased. On the other hand, when the curcumin emulsion was dissolved in water, it was found to have abilities. The curcumin emulsion was nano-homogenized and the size and distribution of the emulsified spheres were measured. It was confirmed to be nano-sized as it appeared as 9.083 nm/100%. In the results of the DPPH radical and ABTS radical scavenging abilities of curcumin nano-emulsion, it was confirmed that there was no change in the antioxidant abilities. In conclusion, water-dispersible curcumin prepared using multi-emulsification technology, and it was confirmed to exhibit antioxidant activity and emulsion stability.

SPG (Shirasu porous glass) 원통형 막을 회전 시키는 회전 막유화를 사용하여 칼슘 알지네이트 미소 구체를 제조 할 때, 단분산 미소 구체를 제조하기 위한 회전 막유화 공정변수들의 최적 조건을 결정하였다. 회전 막유화의 공정 변수로는 막의 회전 속도, 막간 압력차, 연속상에 대한 분산상의 비율, 알지네이트 농도, 유화제의 농도, 안정제 농도, 가교제 농도 및 막의 세공 크기를 설정하고, 이들 변수로 제조된 알지네이트 미소 구체의 크기와 단분산성에 미치는 영향을 검토하였다. 이 결과 회전 막유화의 공정 변수들 중에서 막모듈의 회전 속도, 유화제의 농도, 가교제의 농도가 증가 할수록 미소 구체의 크기 가 감소하였으며, 반면에 연속상에 대한 분산상의 비율, 막간 압력차, 알지네이트 농도가 증가할수록 미소 구체의 크기가 증 가하였다. 세공 크기 3.2 μm인 SPG막을 사용한 회전 막유화에서 공정변수 조절을 통해 최종적으로 입자 크기가 4.5 μm의 단분산 알지네이트 미소 구체의 제조가 가능하였다.

PURPOSES : The purpose of this study is to analyze the effect of ions in emulsion asphalt on recycling cold asphalt concrete and suggest the possibility of using anionic and nonionic emulsion asphalt. METHODS : In this study, indirect tensile strength, toughness, tensile strength ratio, and dynamic immersion tests were conducted to determine the effects of cation, anion, and non-ion emulsified asphalt on the cold recycled asphalt mixture. Crack resistance was evaluated through indirect tensile strength and toughness tests and the tensile strength ratio and dynamic immersion test were evaluated through tensile strength ratio and dynamic water immersion test. RESULTS : Indirect tensile strength and toughness measurement results demonstrated that the mixture using anion and non-ion emulsified asphalt tended to be higher than that using cation emulsified asphalt; this is due to the high content of reclaimed asphalt pavement with a cationic or ionic surface, which is related to the use of cation-emulsified asphalt in the mixture and has shown a low strength tendency. The tensile strength ratio measurement demonstrated that the mixture using non-ion emulsified asphalt tended to be approximately 15 % higher than that of the anion mixture. This demonstrated that the chemical additive used in the mixture showed a complete hydration reaction with the distribution to the mixture. The dynamic immersion test indicates that the aggregate film rate of asphalt is highly influenced by the surface electric charge of the new aggregate while the ionicity effect appears to be insignificant, at 75 - 85 %, when circular aggregates are used. CONCLUSIONS : High reclaimed asphalt pavement content in cold recycled asphalt mixture, as well as non-ion and anionic emulsified asphalt, is advantageous, reducing cracking and improving moisture resistance. It is believed that anions and non-ions may be better utilized than applying the existing criteria to the cold temperature recycled asphalt mixture with high reclaimed asphalt pavement content. In addition, if the scope of the emulsified asphalt is expanded, various additives can be used, which will require analysis of materials, such as fertilizers and additives.

This study investigated the substitution effect of phosphate and isolated soybean powder (ISP) by Allomyrina dichotoma larvae powder (AP) in emulsion sausage. The sausages were prepared for five treatments: 1) positive control (PC): sausages manufactured with sodium pyrophosphate (0.3%) and ISP (1%); 2) negative control (NC): sausages manufactured without sodium pyrophosphate, and ISP; 3) phosphate replacement (PR): sausages manufactured with ISP and AP (1%); 4) ISP replacement (IR): sausages manufactured with sodium pyrophosphate and AP; 5) phosphate and ISP replacement (PIR): sausages manufactured with AP. The 1% AP extract showed DPPH radical scavenging (45.65±2.468%) and metal chelating (22.46±3.559%) activity. The high pH value of AP (8.03) increased the pH of the meat batter of PR, IR, and PIR (p<0.05), but there was no inhibitory effect on cooking loss. Cooking loss of IR was not significantly different with PC due to phosphate. The addition of AP decreased the L* and a* values and increased the b* values, and decreased hardness, chewiness, and springiness of PR, IR, and PIR (p<0.05). AP did not inhibit lipid oxidation in sausages, in contrast to phosphate. In sensory evaluation, the addition of AP resulted in low scores for all sensory parameters of the sausages, although most panels had normal or positive awareness (p<0.05). Aroma was more influential on samples than color. Overall, AP did not replace phosphate and ISP in the sausages. Therefore, processes such as eliminating unique aroma and color and increasing solubility through particle size control are necessary to use AP as a protein source.

본 연구에서는 계면막 조성이 유화된 생선기름의 지방질 산화에 미치는 영향을 평가하기 위해, 소수성 부위의 길이는 같지만 친수성 부위의 크기가 다른 비이온성 에톡실화 지방산 알코올 유화제를 혼합하여 에멀션을 제조했 다. 또한 산화방지제의 극성이 에멀션 지방질 산화에 미치는 영향을 평가하기 위해 에멀션에 지용성 산화방지제 (tert-butylhydroquinone (TBHQ)) 및 양친매성 산화방지제(lauryl gallate)를 첨가했다. 생선기름 에멀션의 지방질 산화 속도(lipid peroxid와 thiobarbituric acid-reactive substance (TBARS))는 유화제의 친수성 머리 부위와 농도에 큰 영향 을 받았다. 친수성 부위가 작은 유화제와 큰 유화제를 1:1 비율(몰농도 기준)로 1.00 mM 및 2.93 mM가 되도록 혼 합하여 에멀션을 제조했다. 유화제의 농도가 각 1.00 mM과 2.93 mM로 제조된 에멀션 모두에서 lipid peroxide의 생 성 속도는 차이가 없었지만, TBARS는 유화제의 농도가 1.00 mM인 에멀션에서 더 빠르게 생성되었다. 에멀션의 계면막 조성과 관계없이 lauryl gallate는 TBHQ보다 더 높은 산화방지활성을 보여주었다.