바이오의약품 시장이 성장함에 따라 분리정제공정의 연구를 통해 비용 절감을 위한 연구가 활발히 진행되고 있 다. 본 연구에서는 새로운 정용여과 장치를 개발하여 바이오의약품 제조 공정에서의 완충액 교환 성능 평가를 수행하였다. 해 당 방법은 가변 부피 정용여과의 방식을 사용하였으며 전량여과 방식을 사용하였다. 이를 통하여, 완충액 사용량을 약 55% 감소시킬 수 있었다. 또한 역흐름을 통해 막의 파울링을 제어하여 초기 유량의 70%를 복구하며 유량의 감소를 완화할 수 있 었으며 교반을 통해 공정시간을 약 52.8% 단축시킬 수 있었다. 또한 새로운 정용여과 장치를 사용하여 연속공정으로의 전환 을 제안한다. 공정의 체류량을 감소시킬 수 있으며, 이는 초소형화 공정을 가능하게 한다. 초소형화 공정을 통해 적은 용량을 사용하여 다양한 조건에서의 신속한 공정 설계를 가능하게 한다. 하지만 고농도에서의 추가 실험을 통해 상업용 공정에서의 사용 가능 여부에 대한 증명이 필요하다.

Purpose This study aimed to develop and evaluate a simulation-based autotransfusion device training program to enhance the clinical performance, performance confidence, and educational satisfaction of post-anesthesia care unit (PACU) nurses. Methods: A single-group pretestposttest study was conducted with 30 PACU nurses. The program, based on the ADDIE model, included orientation, simulation training, and debriefing. Data were collected using validated tools before and after the program and analyzed using the Wilcoxon signed-rank test. Results: Clinical performance improved from a median of 30.00 to 43.00 (Z =−4.78, p < .001). Performance confidence increased from 31.00 to 47.50 (Z =−4.71, p < .001), while educational satisfaction rose from 26.00 to 40.00 (Z =−4.73, p < .001). Conclusions: The simulation-based program effectively enhanced the clinical performance, performance confidence, and education satisfaction of PACU nurses. These findings underscore the value of simulation-based training for enhancing nurses’ competence in using complex, high-risk medical devices.

With the rapid expansion of personal mobility (PM) devices as urban transport alternatives, the associated safety risks have increased significantly. Although previous studies have offered insights into user behavior and accident traits, more integrated approaches that consider spatial and administrative contexts are required to better understand the factors affecting accident severity. This study investigated the factors influencing accident severity involving PM devices in Seoul, South Korea by employing a cross-classified multilevel model (CCMM) to account for both police jurisdiction and regional characteristics. Analyzing the 2021 data from the Traffic Accident Analysis System (TAAS), the model showed strong validity (ICC: 15.8%, DIC: 697.2), outperforming the logistic and hierarchical models. Key predictors of higher severity included crashes in non-standard areas (e.g., other than single roads or intersections), helmet non-use, and older age of victims and perpetrators. Violations, such as exceeding passenger capacity, were negatively associated with severity. Industrial areas and high subway station densities reduced the severity, reflecting the benefits of pedestrian-friendly infrastructure. Larger areas covered by police officers significantly increased the severity, revealing enforcement limitations. The 2021 Road Traffic Act revision has had no statistically significant impact. These results highlight the need for integrated policies that combine infrastructure improvements, enhanced enforcement, and behavioral changes to reduce the severity of PM-related accidents in urban environments.

Our study experimentally evaluates the structural characteristics of a Cone-Shaped Friction Isolator (CFI) as part of research on sliding bearings. With its relatively simple configuration and effective restoring mechanism, the CFI has significant practical implications for structural engineering. We designed the shape and components of the CFI, and its operation and restoring mechanisms were theoretically reviewed. A prototype of the CFI was developed, and structural characteristic experiments were conducted, focusing on design parameters such as the cone’s inclination angle, the friction coefficient of the contact surface, the magnitude of the vertical load applied to the isolator, and the horizontal loading frequency. The experimental results provide valuable insights into the structural characteristics of devices in terms of critical shear force and restoring shear force.

This study developed and evaluated a non-coagulant dredged sediment treatment system as an eco-friendly river dredging and management technology. From 2014 to 2023, heavy rain damage in South Korea amounted to approximately 2.8 trillion KRW, with a sharp increase since 2020. River dredging has been recognized as a crucial countermeasure, and this study aimed to minimize the environmental impact of conventional dredging methods by introducing a non-coagulant treatment system. The developed system utilizes a remotely operated vehicle (ROV) to suction dredged sediment, which is then processed through sedimentation and filtration to separate solids and discharge treated water. Field tests were conducted in Seohwa Stream, Okcheongun, Chungcheongbuk-do. Results showed that the turbidity increase within the ROV operation area was minimal at 3.8%, and the suspended solids (SS) removal rate was 100%. Additionally, the system is akinetes discharge concentration was confirmed to be 0 cells g-1, demonstrating its effectiveness in water quality restoration. These findings confirm that the non-coagulant dredged sediment treatment system reduces environmental impact while ensuring efficient dredging and water quality enhancement. The proposed technology is expected to serve as a sustainable solution for river dredging and management.

We developed a filling seal ring packing machine and carried out the conveying distance and container airtightness tests, and obtained the following results. As a result of testing whether the packaging paper is within 25mm of conveying distance and whether it is suitable for achieving the goal, the prototype with the target feeding distance of 23mm was shortened to 16.4mm for the right pavement line and 20.4mm for the left line, saving 80% compared to the existing one. As a result of the test of the automatic packaging machine for filling and sealing the air tightness of the container, it was confirmed that the air tightness was 100% maintained.

Water-soluble substances like hydrogen fluoride, generated in semiconductor manufacturing, pose serious health and environmental risks, underscoring the need for effective capture devices. Vertical liquid capture devices help by aggregating and discharging hazardous substances with water, but their design can lead to backflow during abnormal operations, causing unintended releases and impacting efficiency and safety. This study seeks to improve a vertical liquid collection device’s containment performance by optimizing its geometry. The vertical wall was rotated at various angles and directions, and turbulent kinetic energy and streamline distribution were analyzed to assess vortex formation and flow characteristics. These structural modifications identify optimal conditions to control hazardous substance migration, offering insights for future pollutant removal device designs.

In this study, we aim to classify personal mobility (PM)-related traffic crash data into four categories: PM-to-vehicle, PM-to-pedestrian, PM-single, and vehicle-to-PM crashes, and analyze the factors influencing the severity of each crash type. To overcome the limitations of existing studies in explaining the impact of independent variables on ordinal dependent variables, a random forest model was combined with the Shapley additive explanation technique. This approach visualizes the influence of independent variables on a dependent variable, providing clearer insights and enhancing interpretability. The analysis of PM traffic accidents, categorized into at-fault, single-vehicle, and victim accidents, revealed distinct key factors for each type. The main contributors to the severity of crashes caused by PM are traffic violations by teenagers and collisions with elderly pedestrians. Single-vehicle accidents were predominantly caused by overturn incidents, with inadequate driving skills among PM users aged 40 years and older, and significantly increasing severity. Victim accidents primarily occur at intersections, where the behavior of the at-fault driver and age of the PM user are critical factors influencing the severity. We identified various factors influencing the severity of PM crashes by type, highlighting the need for tailored policy measures. Proposed policies include physically separating bicycle–pedestrian shared spaces and strictly regulating illegal PM sidewalk riding, introducing PM licenses for teenagers to ensure compliance with traffic rules, and implementing regular safety education programs for all age groups. Although this study applied a new analytical technique, it relied on limited crash data, thus limiting the results to estimates.

Toilet liquid-type cleaners utilize operating technology that employs buoyancy mechanism to inject uniform amount of cleaning solution. Flow characteristics of velocity and pressure distributions in the flow field of toilet flush cleaner injection device have been analyzed with CFD method. The flow rate decreases near the inlet of the system, where it contacts the container of the cleaning liquid bottle. It then increases near the injection device stopper and decreases again as it moves toward the system outlet The height of the cleaning solution decreases from 12 cm to 3 cm when using the spray device, the average outlet velocity decreases by approximately 73%. The solution level difference increases from 1.616 cm to 3.216 cm, the inlet velocity decreases by approximately 4.1%~5.6%. These predicted results can be widely applied as basic conceptual design data for highly efficient toilet flush cleaner injection device.

The importance of indoor air quality has significantly increased after the COVID-19 pandemic. This study analyzed the energy consumption of a ventilation system based on various operating methods considering indoor and outdoor conditions. From March to May 2024, experiments were conducted on ventilation systems installed in a hospital in Incheon, comparing the experimental and control groups. The results showed that using the bypass mode in the experimental group reduced total energy consumption by 25.34% compared to the control group. Additionally, utilizing the air-cleaner mode further reduced energy use. This study demonstrates that optimal use of bypass and air-cleaner modes can enhance energy efficiency. Further research is needed to verify long-term applicability under diverse conditions.

This study developed an unmanned autonomous moving algae collection device (HAMA-bot) to remove high-density algae concentrated in the waterfront of urban agricultural reservoirs, and analyzed the effect of algae removal after field application to medium-sized urban reservoir. The algae reduction effect (Chl-a) of the study site in the reservoir by the HAMA-bot operation showed an average 18.5% higher in the treatment area compared to the control area before operation, while the average reduction of 24% in the treatment area after operation. In addition, the Chl-a removal rate, which directly analyzed the influent and effluent of HAMA-bot, showed a very high level with an average of 96.9% (94.7~99.2%). Currently, it is optimized for urban reservoirs and manufactured on a small scale, but it is a useful tool that can be applied on a large scale to large dams and rivers, and it is considered that the field applicability would be improved with the optimized scale.

본 연구는 금속성 물질로 인해 발생하는 자화율 인공물(susceptibility artifact)의 정확한 길이 측정을 위해 자체 제작한 팬텀을 이용하여 분석하였다. 치과용 임플란트 고정체를 자체 제작한 아크릴 팬텀에 위치시키고, T2 강조 영상을 통해 자화율 인공물을 검사하였다. 자화율 인공물의 길이를 팬텀 기반 측정법과 선 프로파일 기반 측정법을 사용하여 분석하였고 팬텀 기반 측정법을 기준값으로 선 프로파일 기반 측정법으로 도출된 결과와 비교하였다. 결과 적으로 선 프로파일 기반 측정법에서 배경 신호 기준 25% 허용 범위를 설정했을 때 팬텀 기반 측정법과 가장 유사한 데이터를 얻을 수 있었다. 이를 통해 선 프로파일 기반 측정법이 자화율 인공물 길이의 정량적 측정에 적합할 수 있는 가능성을 확인하였다. 추후 미흡한 부분을 보완한 추가 연구를 통해 자화율 인공물 연구에서 객관적인 데이터 제공이 가능할 수 있게 되기를 기대한다.

In this study, a performance evaluation was conducted on a composite elastic asphalt precast expansion joint developed to replace steel expansion joints that frequently suffer from various damages, such as blow-up owing to increased traffic volume and abnormal weather. Two types of elastic asphalt binders were prepared by mixing a latex-based modifier, and their basic properties and performance were evaluated. Elastic asphalt binders were mixed with 8–13 and 13–19 mm aggregates to prepare elastic asphalt joint mixtures, and their permanent deformation and adhesive performance were evaluated using Hamburg wheel-tracking and direct-shear tests. Elastic asphalt joint blocks and internal reinforcement for crack prevention were applied to produce the elastic composite expansion joints, and their performance was evaluated through contraction–extension tests to determine fatigue cracking, maximum load during contraction– extension, and repeated contraction–extension tests. As a result of the performance evaluation of the developed elastic asphalt binder, both the high- and low-temperature performances were improved, and the temperature sensitivity was superior to that of general asphalt binders, exhibiting high resistance to cracking. In addition, the joint block specimens manufactured by mixing the elastic asphalt binder with 13–19 mm aggregates exhibited excellent permanent deformation in the dynamic stability and Hamburg wheel-tracking tests, and they had higher adhesive performance than the method of repairing with rapid-hardening concrete materials at low and room temperatures, where significant contraction of the concrete joint occurs. We confirmed that when a compression spring-type reinforcement was applied, the compressive force for contraction decreased significantly compared with the unreinforced state, and the tensile force for extension increased, thereby reducing the stress applied to the mixture itself. The composite elastic asphalt precast expansion joint developed in this study is expected to have superior durability against cracks and secure continuity with the road surface through the tensile force dispersing effect using expansion reinforcement. Thus, it has better drivability than the existing steel expansion joint and can absorb shocks such as vibrations and noise applied to a structure.