유두주위게실은 담석의 발생 및 재발에 영향을 주는 위험인자로 보고된 바 있다. 하지만 유두주위게실이 내 시 경 역 행 담 췌 관 조 영 술 ( e n d o s c o p i c r e t r o g r a d e cholangiopancreatography) 시행 중 선택적 담관 삽관의 성공률에 영향을 주는지에 대해서는 논란의 여지가 있다. 다만, 실제 임상에서는 유두주위게실로 인해 선택적 담관 삽관이 어려운 경우가 분명히 존재하며, 이를 해결하기 위한 다양한 방법이 보고되었다. 본고에서는 생검겸자를 이용해 선택적 담관 삽관에 성공한 증례를 보고하고자 한다.

이 연구의 목적은 지난 20년간 국내에서 개최된 세계한상대회의 특성을 고찰 하고 해외에서 처음 개최된 세계한인비즈니스대회와의 비교를 통해 한상네트워 크 특징과 구축과정, 시사점과 향후 개선점을 도출하는 데 있다. 연구 방법은 2023년 LA에서 개최된 세계한인비즈니스대회에 참여하여 총 15명의 한상을 인 터뷰했다. 연구 결과는 다음과 같다. 첫째, 세계한상대회에서 한상네트워크 구 축 활동은 ‘개인적 네트워크 구축 활동’과 ‘소개자를 통한 네트워크 구축 활동’ 등으로 나타났다. 둘째, 이번 미국 LA에서 열린 세계한인비즈니스대회 특징은 주로 재외동포 기업인, 외국인 기업인, 한국광역단체장과 상공인단체 등이 대거 참여한 것으로 나타났다. 셋째, 세계한인비즈니스대회에서 신뢰 관계와 비즈니 스 관계 구축과정은 한민족의 공통된 언어와 문화 기반 신뢰 형성, 한상의 가교 역할 기능, 상호신뢰의 확인 장소, 파트너기업과 비즈니스 거래관계로의 전환 등으로 나타났다. 넷째, 세계한인비즈니스대회는 한상과의 약한 개인 관계에서 상호 비즈니스가 가능한 강한 연대의 거래관계로 발전해 가는 과정을 지원하는 프로그램이지만 실제 대회 현장에서는 개최목적과 비즈니스 성과 사이의 괴리 가 큰 것으로 나타났다. 향후 이러한 문제를 해결해나가기 위한 다각적인 노력 이 필요할 것으로 생각된다. 결론적으로 이번 계기를 통해 세계한인비즈니스대 회가 한상네트워크 구축과정이라는 취지를 명확히 이해하고 이를 바탕으로 향 후 실질적으로 한상 간 네트워크 구축과 실천에 도움이 되는 프로그램으로 보 완해 나갈 필요가 있을 것이다.

PURPOSES : This study aimed to predict the number of future COVID-19 confirmed cases more accurately using public and transportation big data and suggested priorities for introducing major policies by region. METHODS : Prediction analysis was performed using a long short-term memory (LSTM) model with excellent prediction accuracy for time-series data. Random forest (RF) classification analysis was used to derive regional priorities and major influencing factors. RESULTS : Based on the daily number of COVID-19 confirmed cases from January 26 to December 12, 2020, as well as the daily number of confirmed cases in Gyeonggi Province, which was expected to occur on December 24 and 25, depending on social distancing, the accuracy of the LSTM artificial neural network was approximately 95.8%. In addition, as a result of deriving the major influencing factors of COVID-19 through random forest classification analysis, according to the number of people, social distancing stages, and masks worn, Bucheon, Yongin, and Pyeongtaek were identified as regions expected to be at high risk in the future. CONCLUSIONS : The results of this study can help predict pandemics such as COVID-19.

본 연구는 프로그램 운영기준을 확인하기 위해 2018년부터 국내외에서 발표된 치유농업 관련 분야의 실험연구 동향을 분석하기 위해 수행되었다. 식물자원 및 치유농업과 관련된 논문은 총 103편으로, 치유농업 프로그램에 참여하는 연구대상자 규모는 31명 이상, 총회기는 11~20회, 단위 활동당 시간은 60분 이내, 단위 활동간 간격은 주 1회, 기간은 2개월이 가장 많았다. 데이터 정보 변인간 관계를 알아보기 위해 논문기초정보와 그에 따른 데이터 정보 변인인 대상자 정보, 프로그램 정보의 유의한 연관성이나 차별성이 있는지 확인하기 위하여 카이제곱 검정을 실시한 결과, 저자전공과 대상자정보·프로그램 정보는 대부분 항목에서 관계가 있었으나 저자소속, 발행연도, 논문구분, 치유유형 등은 1 또는 2개의 항목에서만 관계가 있었고, 종속변수 치유문제-중분류는 저자소속을 제외한 저자전공, 발행연도, 논문구분, 치유유형 항목 모두에서 유의미한 관계를 보였으며, 치유문제-대분류는 저자소속과 발행연도를 제외한 저자전공, 논문구분, 치유유형 3개의 변인과의 관계가 있는 것으로 나타났다. 본 연구결과를 토대로 향후 치유농업 연구에 기초자료로 제공하고 현장에서의 활용도를 높여 치유농업의 신뢰도를 높이는 데 기여하고자 한다.

The Department of Oral and Maxillofacial Pathology was established in March 1970 by Dr. Young Pill Cho. Successive chairpersons of the department have included Dr. Han Kook Cho, Dr. Jaeo Cho, Dr. Eun Chull Kim, and Dr. Sang Wook Kang, who held the position until 2021. The tasks of the Department of Oral Pathology include conducting lectures and laboratory work for undergraduate dental students, as well as for graduate students pursuing MSD and PhD degrees. The department also engages in research within the field of oral pathology and provides diagnostic services for tissues obtained from diseases affecting the oral and maxillofacial regions. The objectives of the department are to equip students with the appropriate knowledge and skills to diagnose and develop accurate treatment plans for diseases affecting oral and maxillofacial structures through lectures and laboratory work after graduation. Since the establishment of the Master's and PhD programs in Oral and Maxillofacial Pathology, a total of 94 individuals have completed the Master's program, 45 individuals have completed the PhD program, and 1 individual has completed the Master-PhD collaboration program. Each participant completed their respective courses and obtained the appropriate degrees following the evaluation of their graduation theses.

The armillary sphere, an astronomical observation device embodying the Orbital Heaven Theory of the Later Han Dynasty in China, holds both historical and scientific significance. It has been produced in various forms by many individuals since its inception in the era of King Sejong in the Joseon Dynasty. A prominent figure in this field was Nam Byeong-cheol (南秉哲, 1817-1863), known for his work 'Uigijipseol' (儀器輯說), published in 1859, which detailed the history, production methods, and usage of the armillary sphere. This text particularly highlights 21 applications of the armillary sphere, divided into 33 measurements, covering aspects like installation, time, and positional measurements, supplemented with explanations of spherical trigonometry. Despite numerous records of the armillary sphere's design during the Joseon Dynasty, detailed usage information remains scarce. In this study, the 33 measurements described in 'Uigijipseol' (儀器輯說) were systematically classified into six for installation, nineteen for position measurement, seven for time measurement, and one for other purposes. Additionally, the measurement methods were analyzed and organized by dividing them into the ecliptic ring, moving equatorial ring, and fixed equatorial ring of the armillary sphere. In other words, from a modern astronomical perspective, the results of schematization for each step were presented by analyzing it from the viewpoint of longitude, right ascension, and solar time. Through the analysis of Nam's armillary sphere, this study not only aims to validate the restoration model of the armillary sphere but also suggests the potential for its use in basic astronomical education based on the understanding of the 19th-century Joseon armillary sphere.

우리는 길앞잡이(Cicindela chinensis)의 장에서 다양한 공생 미생물들을 분리하였다. 그중 다양한 곰팡이 성장 을 억제하는 세균을 동정하였고 “Ch-1”이라 명명하였다. 우리는 Ch-1 균주를 사용하여 10종의 식물 병원성 곰팡 이와 2종 곤충 병원성 곰팡이의 생장 억제를 확인하였다. 또한 8종의 항생제에 대한 저항성을 확인하였다. 동시 에, 본 균주의 genomic sequence를 수행하였고 유전적, 생화학적, 생리적 특성을 조사하였다. Ch-1균주는 특허등 록과 친환경 미생물제제로 등록하였고 향후 생물학적 방제제로써 활용될 수 있을 것으로 판단한다.

The baculovirus expression system (BES) utilize the p10 or polyhedrin promoter, a very late promoter that exhibits strong transcriptional activity primarily at the end of viral infection, to produce useful recombinant proteins. The burst sequence of the very late promoter is essential for strong transcription, and VLF-1 is a transcription factor that binds specifically to the burst sequence, and it has been reported that it can regulate the amount and timing of expression of protein by the very late promoter. Recently, a VLF-1 constitutively expressing cell line was constructed to increase the production of the target protein, but the effect was minimal. In this study, to find the optimal VLF-1 expression conditions to increase target protein production efficiency, we controlled the expression of VLF-1 through various promoters and evaluated the target protein expression efficiency by the p10 promoter accordingly.

동물의 종 유지에 있어서 교미행동은 매우 중요한 위치를 차지함. 교미과정에서 수컷의 경우 모든 암컷에 대해 성행동을 보이는반면, 암컷은 가장 적절한 교미의 시기를 정하며, 적절한 수컷을 선택하고 교미행동을 보이기 때문에 암컷의 교미행동을 유도하는 과정은 생물학에서 매우 중요한 의미를 지님. 본 연구에서는 초파리 (Drosophila melanogaster) 전자현미경자료와 총신경망분석 (Connectomics)을 이용하여 초파리 뇌에서 암컷의 교미행동을 조절하는 것으로 알려진 pC1신경의 하부신경 pC1b,c가 성적 성숙과정에서 교미를 하고자 하는 욕구 (sexual drive)를 증가시키는 기능을 하는 것을 처음으로 밝힘. 본 연구에서는 처음으로 pC1b,c 신경 내의 cAMP 수준이 교미의 욕구변화를 보여주는 중요한 물질이라는 것을 밝혔고 cAMP의 수준이 오르기 위해서는 신경펩티 드인 Dh44와 그 수용체 GPCR인 Dh44R1과 Dh44R2가 필요하다는 것을 확인함. 또한 cAMP의 변화는 신경내의 CREBB를 통하여 하위 유전자인 pyx (pyrexia)의 발현을 유도한다는 것을 밝힘. 본 연구로 종 유지 메커니즘을 좀 더 이해할 수 있음.

Acetylcholinesterase (AChE) is a key enzyme that terminates impulse transmission by rapidly hydrolyzing the neurotransmitter acetylcholine at cholinergic synapses. Previous studies have discovered a transiently opening channel referred to as the “back door” in Torpedo californica AChE. Previously, we observed that substituting the Tyr391 residue with a Phe residue significantly decreased the catalytic efficiency of recombinant Apis mellifera AChE1 (AmAChE1), while the reverse substitution restored it. Interestingly, substitution of the Tyr391 residue with a Phe residue in AmAChE1 disrupted the formation of the backdoor, while the reverse substitution restored it. This finding suggests that the Tyr-to-Phe substitution impairs backdoor formation, thereby leading to a significant reduction in the catalytic activity of AmAChE1. This serves as one of the driving forces for the functional transition from AmAChE1 to AmAChE2. In this experiment, we also confirmed the gradual restoration and increase in AChE activity by substituting Phe391 in AmAChE1 with Ser, Trp, Thr, Ile, Asn, and Tyr residues through kinetic assay and molecular dynamics simulation.

The genus Megastylus is a moderate group of the subfamily Orthocentrinae, comprising 38 species in two subgenera from worldwide. The subfamily Orthocentrinae is a high proportion of the genera are cosmopolitan in distribution. Orthocentrines are known as almost solitary koinobiont endoparasitoids. We report this genus for the first time from South Korea. In this study, descriptions of some new species, photographs of diagnostic characterists are provided.

The genus Hypsopygia was established by Hübner, 1825, with type species Phalaena costalis Fabricius, 1775. Hypsopygia is characterized by the elongated uncus and valva, and pointed saccus in the male genitalia. It consists of 105 described species (Nuss et al., 2003–2024) in the world, and 11 species have been recorded in Korea (Kim & Paek, 2020; Shin et al., 2023). In this study, we reported one newly recorded species in Korea. Illustrations of adults provided, with information of host plants of all examined species.

Native to southern Europe, Lepisiota frauenfeldi (Mayr, 1855) is an invasive species that has been introduced worldwide through cross-border trade. It has been documented to be distributed in the Mediterranean, Middle East, Africa, and Indo-Malaya. This species, also known as Browsing ant, was first found around a warehouse in Gwangyang, Jeollanam-do, South Korea, and was probably introduced into the country via cargo. The external morphology and gene sequences were checked for taxonomic identification, and it was identified as Lepisiota frauenfeldi based on comparative analysis of the morphological classification key and NCBI data. This study is the first report of a newly invasive alien ant and provides basic data on the species, including external morphological and ecological features and sequencing results.

Insect cuticular extracellular matrices (ECM) including the eggshell and exoskeleton play vital roles in protecting them from natural environmental stresses. However, these chitinous ECMs must be degraded at least in part during embryonic and post-embyonic molting periods to accommodate continuous growth all the way to the adult stage. In this study we investigated the functions of groups I and II chitinases, TcCHT5 and TcCHT10, in turnover of the eggshell and cuticle in Tribolium castaneum. RNAi and TEM analyses revealed that TcCHT10 is required for digestion of chitin in the serosal cuticle for embryo hatching as well as in the old cuticle during post-embryonic molts including larval-pupal and pupal-adult metamorphosis. However, although TcCHT5 is apparently involved in these vital physiological events, TcCHT10 could substitute for TcCHT5 except during the pupal-adult molting when both enzymes are indispensable to degrade chitin in the old pupal cuticle.

This study reports the first Korean records of the genus Acerocnema Becker, 1894, with one new species, Acerocnema saurischia sp. nov., and one newly recorded species, A. flavifrons. A key to the Korean Scathophagidae is provided with morphological diagnosis and images of habitus and male genitalia structures. To assist in species identification, mitochondrial cytochrome c oxidase subunit I (COI) gene sequences were obtained from all specimens to conduct DNA barcoding.

서부마른나무흰개미(신칭)는(Incisitermes minor) 미국 서부와 멕시코 북부를 포함하여 북미 서부가 원산인 종이며 주택을 포함한 목조 구조물에 치명적인 해충이다. 국내에선 2023년 9월 외래생물신고센터를 통해 경남 창원시 진해구의 한 가정집에서 흰개미 유시충이 발견되었다는 민원 신고로 처음 확인되었다. 그 이후 주변 지역 조사 결과 민원인 주택 주변에서 군집비행하는 흰개미 유시충 및 목재 피해 흔적을 통해 군체를 발견 확인하였다. 또한, 최초발견지에서 약 1km 떨어진 한 아파트 단지의 정자 및 그 일대에서 추가 군체가 확인되었다. 본 연구에서 는 채집된 흰개미의 형태와 유전자 정보를 통해 대상종을 확인하였고, 발견 및 피해 상황 정보를 통해 향후 해당 종의 관리를 위한 기초자료를 제공하고자 한다.

Indian meal moth, Plodia interpunctella (Lepidoptera: Pyralidae), is a serious pest of stored products. We assessed the efficacy of combined application of Beauveria bassiana AAD16 and azadirachtin against P. interpunctella under laboratory conditions by using filter paper dipping method. P. interpunctella larvae showed lowest LT50 in combined application of AAD16 and azadirachtin compared to the application of only azadirachtin. The mycosis rate of P. interpunctella larvae was 100% after 14 days of the combined application while AAD16 only application showed 93%. These findings suggest that B. bassiana AAD16 and azadirachtin combined solution can be an effective controlling technique against P. interpunctella larvae.

The subgenus Oropeza Needham, 1908 (Diptera: Tipulidae: Dolichopeza) comprises 27 described species distributed across the Holarctic region. Certain Oropeza species have been reported in neighboring countries of the Korean Peninsula―6 species in Japan, 3 species in China, and 4 species in Russia. Some researchers, such as Byers (1961) and Savchenko (1983), suggested that the distribution of Oropeza cover the East-Palearctic regions, including the entirety of the Korean Peninsula. However, previous records of Oropeza from the Korean Peninsula have not been accepted because of the lack of comprehensive species-level investigations in this region. In this study, we present a new record of the species Dolichopeza (Oropeza) satsuma (Alexander, 1918) in South Korea, with redescription and photographs: general habitus, wing veins, and male genitalia. This finding marks the rediscovery of the subgenus Oropeza in the Korean Peninsula.

The family Erebidae (Lepidoptera: Noctuoidea) is known as one of the largest families in Lepidoptera, comprising about 1,760 genera and more than 24,569 described species worldwide. Within this family, the genus Plecoptera Guenée, 1852, belonging to the subfamily Anobinae, has been documented across the Palaearctic, Oriental, and Afrotropical regions. Here, we introduce the subfamily and genus for the first time in Korea, along with a new species. The diagnosis, description and photographs of adult and genitalia are provided here.