This study investigated the anti-obesity effects of Coriandrum sativum L. ethanol extracts in a high fat diet-induced obesity model (DIO). We confirmed the anti-obesity effects by analysing the expression of the related proteins, weight gain, dietary intake, dietary efficiency, blood biochemistry, histological analysis and western blot analysis. After oral administration of Coriandrum sativum L. ethanol extracts at concentrations of 250 and 500 mg/kg, a significant improvement in dietary efficiency, reduction in weight gain, triglycerides, total cholesterol and LDL-cholesterol in blood lipid was observed for 8 weeks. In addition, improvement in blood glucose and metabolism confirmed through glucose tolerance test was observed. Further, the concentration of alanine transaminase (ALT) in blood was significantly decreased, which improved the fatty liver caused by high-fat diet intake as confirmed by liver tissue analysis. This phenomenon was confirmed to decrease the expression of fat accumulation-related PPARγ and FAS protein in the liver tissue. Especially, it is believed that FAS, a liposynthetic enzyme, has a stronger inhibitory effect than PPARγ. Therefore, Coriandrum sativum L. ethanol extract is thought to improve obesity by reducing blood lipids levels, improving glucose metabolism and inhibiting synthesis of the fat that accumulates in the liver in high-fat diet-induced obesity animal models.

The essential oils of three Coriandrum sativum seeds cultivated from India, Russia and America were evaluated for acaricidal toxicities against Dermatophagoides farinae, D. pteronyssinus, and Tyrophagus putrescentiae. The oils of three C. sativum seeds were analyzed by gas chromatography. The oil of C. sativum seeds cultivated from India included substantially linalool (66.8%) and camphor (6.46%). In the fumigant bioassay, based on the LD50 values against D. farinae, D. pteronyssinus, and T. putrescentiae, the oil of C. sativum seeds cultivated from America (LD50, 2.62, 2.74, and 2.88 μg/cm3) was about 3.75, 3.32, and 4.17 times more active higher than benzyl benzoate (9.85, 9.10 and, 12.01 μg/cm3). The acaricidal activity of the oil of C. sativum seeds cultivated from India was 2.27, 2.03, and 2.64 times higher than that of the benzyl benzoate, followed by Russia oil. These results suggest that the oils of three C. sativum seeds might be used as suitable acaricides.

Commercial plant essential oils from 27 plant species were tested for their nematicidal activities against the pinewood nematode, Bursaphelenchus xylophilus. Good nematicidal activity against B. xylophilus was achieved with essential oils of coriander (Coriandrum sativum), styrax (Liquidamber orientalis) and valerina (Valeriana wallichi). Analysis by gas chromatography-mass spectrometry led to identification of 26, 10 and 4 major compounds from coriander (Coriandrum sativum), styrax (Liquidamber orientalis) and valerina (Valeriana wallichi) oils, respectively. These compounds from three plant essential oils were tested individually for their nematicidal activities against the pine wood nematode. Among compounds, benzaldehyde, trans-cinnamyl alcohol, cis-asarone, octanal, nonanal, decanal, trans-2-decenal, undecanal, dodecanal, decanol, and trans-2-decen-1-ol showed strong nematicidal activity. The essential oils and their described herein merit further study as potential nematicides against the pine wood nematode.

Coriandrum sativum L., an annual herbaceous plant of Apiaceae family. The present study evaluated the anti-oxidant activities and anti-inflammatory effects of ethanol extracts of C. sativum. The anti-oxidant activities of C. sativum were measured by total contents of polyphenol, flavonoid, DPPH and ABTS radical scavenging and reducing power activity. And anti-inflammatory effects of C. sativum were measured by LPS-induced RAW 264.7 cells. The results showed that the contents of total polyphenol and flavonoid were 76.03 ± 1.36 mg of gallic acid equivalents/g and 182.23 ± 4.32 mg of rutin equivalents/g at concentration 1 mg/ mL of C. sativum. The DPPH radical scavenging activity was found to be 52.8% at 500 μg/mL. The ABTS radical scavenging activity was shown in 58.3% after exposure to 1,000 μg/mL. Reducing power activity was found to be 66.8% at 2,000 μg/mL. The inhibitory effect of NO production was found to be 65% concentration 500 μg/mL. In the generation quantity of inflammatory cytokines such as TNF-α and IL-1β in cell culture medium, the expression levels of inflammatory proteins in cells were showed decrease with the increase of concentration. Therefore, we suggest that the C. sativum should be a potential source of alternative anti-inflammatory drug with good anti-inflammatory effects.

Background : In recent years, the demand for oriental cuisine has increased due to the increase of multicultural families and dietary changes, and Coriandrum sativum is also consumed steadily. Therefore, this study was conducted to establish the optimum planting density for high-quality seed production of Coriandrum sativum in order to increase the utilization of leafy vegetables and establish a foundation for production throughout the year through house cultivation Methods and Results : This experiment was carried out from March to August 2017 at a house facility located in Namwon-si (500 m above sea level) in Jeollabuk-do. Seeds of Coriandrum sativum were sown on March 10, 2017 and planting density was set at 4 levels of 10 × 5 ㎝, 10 × 10 ㎝, 10 × 20 ㎝, and 10 × 30 ㎝. Seeds were harvested on August 2 and 142 days after sowing. Growth characteristics of C. sativum were investigated on May 16, 66 days after sowing. Plant height, leaf length and leaf width were good at 52.9 ㎝, 3.8 ㎝, and 4.1 ㎝ in planting density of 10 × 10 ㎝, respectively, but there was no statistically significant difference between treatments. As a result of examining the number of leaflets per plant, 20.9 leaves in 10 × 30 ㎝ treatment was the best and the difference was significant. The fresh weight of the overground part was the highest at 2,322 ㎏/10a in 10 × 10 ㎝ treatment. The total fresh weight of the overground and underground parts were 2,633 ㎏/10a and 2,572 ㎏/10a at 10 × 10 ㎝ and 10 × 20 ㎝, respectively. The total weight of seeds per treatment was the highest at 146 ㎏/10a at 10 × 10 ㎝ treatment, but the difference was not significant. Conclusion : As a result of the experiment to determine the proper planting density, the growth characteristics and the total weight of seeds were good at 10 × 10 ㎝ treatment, but there was no statistically significant difference. Therefore, when C. sativum are cultivated for the purpose of seed production, the planting density of 10 × 30 ㎝ is considered to be the most appropriate for seed requirement and labor saving.

This study was conducted to obtain the basic data related to seed characteristics and germination conditions of the Coriandrum sativum L. at different storage condition and temperature. The shape of fruit was oval with light brown color. Fruit was mericarp, biloculate, with one ovule in each locus. The length and width of seed were 1.37 ± 0.067㎜ and 0.52 ± 0.039㎜, respectively. Weight of 1,000 seeds was 6.55 ± 0.15 g. Seeds which were stored at room (15℃) and cold temperature (4℃) in vinyl container showed the highest germination rate (93.3%) under the room temperature germination condition. Percentage of germination in cold and freeze temperature was 20% and 0%, respectively. Germination rate of room storage seeds with paper container increased to about 91.3%, however, decreased in cold (4℃) and freeze storage (−20℃) with paper container (76.7% and 78.0%, respectively). Germination rate of seed in vinyl stock container was better than that of paper stock container. Germination rate of seeds stored at room temperature for 4 years (2010 - 2013) ranged from 80.0% to 91.3%. Therefore, coriander seeds are expected to be stored at room temperature for increasing the germination rate and keeping a long term.