바이러스 여과는 동물세포기반 바이오 의약품 제조에서 중요한 정제 공정으로, 특수하게 설계 및 제조된 분리막 을 사용하여 바이러스를 차단하고 항체 등 바이오 의약 물질을 선택적으로 통과시킨다. 바이러스 필터의 핵심 성능인 바이러 스 제거율과 항체 및 단백질의 회수율은 필터의 기공 구조와 대칭성뿐만 아니라, 여과 조건(표면 다공성, 압력, 유속, pH, 이 온 강도 등)에 따라 달라진다. 특히 단백질 오염은 비가역적 및 가역적 오염으로 구분되며, 추가로 blocking 모델을 통해 정밀 하게 분석하였다. 본 총설에서는 바이러스 필터 및 여과 공정의 이해 및 최적화를 위해 필터 구조, 제거 기작과 막오염 현상 을 소개하고, 바이러스 여과 공정에서 제거성능에 영향을 미치는 다양한 인자를 분석해보고자 한다.

Zinc oxide has attracted attention due to its high functionality, including chemical stability, high biocompatibility, and excellent optical properties. In particular, when the particles are nano-sized, they exhibit new characteristics, making them suitable for application in UV-filters, photo-catalysts and cosmetics. This paper provides an overview of nano zinc oxide used for UV filters, and summarizes domestic and international production technology and the industrial status of zinc oxide nano-powder. First, the concept and principle of the nano-sized zinc oxide manufacturing process is provided, and various types of manufacturing methods are analyzed, namely, wet process, dry process, and powder process. Next, the results of an analysis of the domestic sunscreen market size and company status are provided. The production processes of major domestic companies and their product characteristics, such as particle size, purity, surface treatment, and transparency of the zinc oxide powder being produced, are analyzed and provided. The characteristics of zinc oxide produced for use in sunscreens, both domestically and internationally, can be summarized as follows. Manufactured zinc oxide powder is white or transparent, and particle size typically ranges from 30 to 200 nm on average, although non-nano sized powders have also been developed in recent years. When used as a coating, the surface to be coated is typically treated with substances such as silicone oil or silane, and the powder is formulated into products by dispersing it in oil- or water-based systems.

포도 ‘My heart’의 기내증식과 기외이식 후 생장에 있어서 배양용기에 부착한 미세공극 Filter 처리가 건전한 유묘를 생 산하는데 효과적인 방법을 찾고자 실시하였다. 미세공극 Filter는 환기구 크기별로 White filter type (50.0 mm×3.5 mm)과 Green filter type (50.0 mm×7.0 mm) 으로 구분하여 밀폐 처리와 비교하였다. Shoot tip 배양에 있어서 Green filter type에서 shoot 분화율이 75%로 White filter type 77% 와 밀폐처리 80% 보다 낮았지만 투명화 shoot 발생율은 4% 로 White filter type 13.4%, 밀폐처리 24.7%에 비하여 9.4－ 20.7%가 적었다. 전체 배양묘의 54.9%가 투명화 발생이 되 었을 때 Green filter type으로 90일 동안 계대 배양하고 조사 한 결과 투명화율은 11.8%로 감소하였고 분화한 shoot 수는 89개에서 915개로 증가하였다. Filter type에 따라 IBA 2.0 mg·L-1를 첨가하여 30일 동안 배양을 하였을 때 Green filter type에서 기내 발근율 100%, 뿌리 수 7.3개, 엽수 10.0개로 White filter type과 밀폐 처리보다 좋았다. 기외 이식하고 15 일 후의 유묘 생존율도 Green filter type에서 100%로 다른 처 리에 비하여 1.5－29.5% 더 높았고 초장이 11.0cm, 생체중이 1.7g 으로 가장 양호하였다. 미세공극 Green filter 처리는 포 도 ‘My heart’의 기내배양에서 shoot 투명화를 감소시키고 shoot와 뿌리 생성을 촉진시키고 기외이식 후 생장은 통계적 으로 유의하게 확인되어 건전한 유묘 생산에 효과적이었다.

본 논문에서는 지진 하중으로 인한 급격한 구조손상탐지를 수행하기 위해 분산점 칼만필터(Unscented Kalman Filter, UKF)와 파티 클 필터(Particle Filter)를 소개하고 지진 손상 시나리오에 적용 및 비교･검토하였다. 이때, 비선형 전단 빌딩을 모사하기 위해 Bouc-Wen 모델을 사용하였고, 급격한 변화를 추정하기 위해 추가적으로 적응형 기법(Adaptive rule)인 Adaptive Jumping Method를 두 필터 모두에 적용하였다. 적용 결과 두 오리지날 필터 모두 급격한 손상 시점과 정도를 파악하지 못하였고, 적응형 기법을 반영하였 을 경우에만 시점 파악이 가능하였다. 하지만, 여전히 손상 정도를 정확히 파악하지 못하였고, 두 방법 모두 제안된 적응형 기법을 새 로이 조정하였을 경우에 정확한 추정이 가능함을 확인하였다. 최종적으로 계산시간을 고려하였을 때, 새로운 형태의 적응형 기법을 적용한 UKF 사용을 제안하는 것으로 비교 검토를 수행하였다.

Air conditioner filters purify the air of indoor environments by removing air pollutants and supporting the efficiency of the unit’s cooling function. However, an air conditioner filter can become a microenvironment in which some fungi can grow as dust continues to accumulate and favorable humidity conditions are formed. Fungal growth in air conditioner filters could lead to fungal allergies or fungal diseases, in addition to emitting a foul odor. In an effort to understand what species causes this malodorous problem, we investigated the diversity of fungi found in air conditioners. Fungi were sampled from the collected air conditioner filters and grown on DG18 agar media. After purification for pure isolates, species identification was undertaken. Colony morphology was observed on PDA, MEA, CYA, and OA media. Microstructures of fruiting body, mycelia, and spores were examined using a light microscope. Molecular identification was performed by PCR and sequencing of PCR amplicons, and molecular phylogenetic analysis of sequenced DNA markers, including the Internal Transcribed Spacer (ITS), the 28S large subunit of the nuclear ribosomal RNA (LSU rDNA), the β-tubulin (BenA) gene, the Calmodulin (CaM) gene, and the DNA-directed RNA polymerase II subunit 2 (RPB2) gene. Through this identification process, we found two fungal species, Aspergillus miraensis and Dichotomopilus ramosissimus, which are unrecorded species in Korea. We will now report their morphological and molecular features.

For motor controller designers, building a simulation environment is not a difficult process. After verifying the controller by simulation, it is common to select 20kHz for the current control loop, 1kHz for the speed loop, and 100Hz for the position loop when implementing the actual HW embedded system. This is because maximized cycles (20kHz) for each control loop are unnecessary in control theory and are a waste of cost and HW resources. However, in a simulation environment, each loop will often have the same control cycle (20kHz maximum). This is because we think it is unnecessary to reflect this part in the simulation. In this paper, it is shown that the difference in the sampling time of each control loop makes a big difference in the simulation result, and as a solution, it is proposed to apply LPF to the position loop output stage. In the process, the reasons for the differences were analyzed, and the effect of LPF, the reason for application, and the feasibility of implementation were proved by actual software coding.

Porous ceramics are used in various industrial applications based on their physical properties, including isolation, storage, and thermal barrier properties. However, traditional manufacturing environments require additional steps to control artificial pores and limit deformities, because they rely on limited molding methods. To overcome this drawback, many studies have recently focused on fabricating porous structures using additive manufacturing techniques. In particular, the binder jet technology enables high porosity and various types of designs, and avoids the limitations of existing manufacturing processes. In this study, we investigated process optimization for manufacturing porous ceramic filters using the binder jet technology. In binder jet technology, the flowability of the powder used as the base material is an important factor, as well as compatibility with the binder in the process and for the final print. Flow agents and secondary binders were used to optimize the flowability and compatibility of the powders. In addition, the effects of the amount of added glass frit, and changes in sintering temperature on the microstructure, porosity and mechanical properties of the final printed product were investigated.

The SLA 3d printer is the first of the commercial 3D printer. The 3D printed output is printed hanging on the bed that move to the upper position. Sandblasted bed is used to prevent layer shift. If sandblasting is wrong, the 3D printed output is layer shifted. For this reason, 3D printer manufacturing companies inspect the bed surface. However, the sandblasted surface has variety of irregular shapes and craters, so it is difficult to establish a quality control standard. To solve problems, this paper presents a standardized sandblasting histogram and threshold. We present a filter that can increase the classification rate.