This study aimed to investigate the difference that convolutional neural network(CNN) shows in the determining osteoporosis on panoramic radiograph by performing a paired test by inputting the original image and the limited image including the cortical bone of the posterior border of the mandible used by radiologists. On panoramic radiographs of a total of 661 subjects (mean age 66.3 years ± 11.42), the area including the cortical bone of the posterior part of the mandible was divided into the left and right sides, and the ROI was set, and the remaining area was masked in black to form the limited image. For training of VGG-16, panoramic radiographs of 243 osteoporosis subjects (mean age 72.67 years ± 7.97) and 222 normal subjects (mean age 53.21 years ± 2.46) were used, and testing 1 and testing 2 were performed on the original and limited images, respectively, using panoramic radiographs of 51 osteoporosis subjects (mean age 72.78 years ± 8.3) and 47 normal subjects (mean age 53.32 years ± 2.81). The accuracy of VGG-16 for determining osteoporosis was 97%, in the testing 1 and 100% in the testing 2. When determining osteoporosis on the original image, CNN showed sensitivity in a wide range of areas including not only the inferior cortical bone of the mandible but also the maxillary and mandibular cancellous bone, cervical spine, and zygomatic bone. When the same ROI including the lower inferior cortical border of the mandible of the osteoporosis group was applied and the sensitive region was compared between the original image and the limited image, the original image showed wider sensitive region in cancellous bone and cortical bone than on the limited image (p<.05). Since osteoporosis is a disease that affects throughout the skeletal system, this finding seems very valid.

This study was conducted to analyze the productivity and economic feasibility of truss-limited tomatoes (Lycopersicon esculentum L.) grown at a high density in Cambodia during the rainy season. During the rainy season in Cambodia, due to excessive rain and very high temperature, tomatoes cannot grow well in an open field, leading to a greatly reduced yield. High density truss-limited cultivation (HDTLC) of tomatoes can shorten the growing season and increase yields. In conventional cultivation (control), tomatoes were transplanted at a spacing of 70×40 cm and harvested up to the 4th fruit cluster. In HDTLC, tomatoes were transplanted at a spacing of 20×20 cm or 25×25 cm and harvested up to the 2nd fruit cluster. Plant heights in HDTLC were higher than those in the control at 22 days after transplanting (DAT). At 39 DAT, plant heights did not differ between 25×25 cm and control. At 60 DAT, plant height, stem diameter, leaf length, and leaf width of the HDTLC were lower than those of the control. Fruit length and width were also lower in HDTLC compared to those of the control. However, sugar content was more than 19% higher in HDTLC compared to that in the control. Yield per plant of the control was the highest, but yields per ha in HDTLCs were 99% (20×20 cm) and 38% (25×25 cm) higher, respectively, compared to that of the control. No pesticides were used for disease control in this experiment. However, to ensure yield, it is recommended to observe the disease status of plants and spray pesticides at the appropriate time. The disease index (1: disease-free; 5: all leaves were disease-infected) of late blight (Phytophthora indestans) was significantly higher for 20×20 cm (4.5) and 25×25 cm (3.6) groups compared to the control (2.0). Income with 20×20 cm (5,668 thousand KRW) and 25×25 cm (1,863 thousand KRW) were 4.9 and 1.6 times higher, respectively, compared to that with the control (1,149 thousand KRW). So, we want to spread the HDTLC technology, which transplanting of tomato seedlings at 20×20 cm intervals and harvests up to 2nd fruit cluster, to Cambodian farmers.

In this study, we collected and analyzed the current status of licenses for the limited fishery business and divided the problems related to licenses for the limited fishery business into partial damage compensation and cancellation compensation areas. In the case of partial damage compensation areas due to existing public water use projects, it is suggested that the issuance of licenses for limited fishery businesses should be reconsidered. In the case of cancellation compensation areas, it is recommended that the disposition of communal fishery businesses that do not require capital investment should be the principle. If capital such as facilities are invested, compensation should be made by Article 52 of the Enforcement Decree of the Land Compensation Act if the licenses for limited fishery business are closed due to other development projects. In addition, we proposed an improvement plan to establish a rational management system for licenses for limited fishery businesses. In addition to these improvement measures, we hope that further investigation and research on licenses for limited fishery business, which have been insufficient so far, will be conducted to promote the comprehensive use of fisheries resources and waters and the sustainable development of fisheries that are the objectives of the Fisheries Act, and contribute to the improvement of the quality of life of the people and the balanced development of the national economy.

Background: Pluripotent stem cells (PSCs) including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) offer the immense therapeutic potential in stem cell-based therapy of degenerative disorders. However, clinical trials of human ESCs cause heavy ethical concerns. With the derivation of iPSCs established by reprogramming from adult somatic cells through the transgenic expression of transcription factors, this problems would be able to overcome. In the present study, we tried to differentiate porcine iPSCs (piPSCs) into endothelial cells (ECs) for stem cell-based therapy of vascular diseases. Methods: piPSCs (OSKMNL) were induced to differentiation into ECs in four differentiation media (APEL-2, APEL-2 + 50 ng/mL of VEGF, EBM-2, EBM-2 + 50 ng/ mL of VEGF) on cultured plates coated with matrigel® (1:40 dilution with DMEM/F-12 medium) for 8 days. Differentiation efficiency of these cells were exanimated using qRT-PCR, Immunocytochemistry, Western blotting and FACS. Results: As results, expressions of pluripotency-associated markers (OCT-3/4, SOX2 and NANOG) were higher observed in all porcine differentiated cells derived from piPSCs (OSKMNL) cultured in four differentiation media than piPSCs as the control, whereas endothelial-associated marker (CD-31) in the differentiated cells was not expressed. Conclusions: It can be seen that piPSCs (OSKMNL) were not suitable to differentiate into ECs in the four differentiation media unlike porcine epiblast stem cells (pEpiSCs). Therefore, it would be required to establish a suitable PSCs for differentiating into ECs for the treatment of cardiovascular diseases.

북한의 군사전략에 대해 기존대로 한반도 전 지역을 석권한다는 군사전 략이 지속되고 있다는 주장과 변화하고 있다는 주장이 아직도 맞서 고 있는 상황이다. 연구 목적은 최근 안보환경의 변화와 김일성－김정일 －김정은으로 이어지는 집권자의 변화 기간 동안 북한 군사전략의 변화 를 분석하고, 핵무력 완성 이후 경제건설에 집중하겠다는 북한의 군사전 략의 변화를 제한전 하 군사전략으로 전망해 보고자 하였다. 연구 방 법은 문헌조사를 통한 질적연구를 주로 실시하였고, 김일성 집권 이후부 터 현재까지의 시기를 망라하여 군사전략의 구성요소를 중심으로 분석하 였다. 연구 결과 김정은은 체제안정을 최우선으로 기존의 전면전 보다는 핵무기 사용을 위협하며 제한전을 추구하는 군사전략을 채택할 것으로 분석되었고, 이를 군사전략의 구성요소를 중심으로 전망해 보았다. 이에 대비하여 한국군은 기존의 전면전 중심에서 북한의 제한전 하 군사전략 에 대응하는 군사전략을 병행하여 발전시킴이 요구되고 있다.

Background: The gastrocnemius tightness can easily occur. Gastrocnemius tightness results in gait disturbance. Thus, various interventions have been used to release a tight gastrocnemius muscle and improve gait performance. Moreover, focal muscle vibration (FMV) has recently been extensively researched in terms of tight muscle release and muscle performance. However, no study has investigated the effects of FMV application on medial gastrocnemius architectural changes. Objects: In this study, we aimed to investigate the effects of FMV on medial gastrocnemius architecture in persons with limited ankle dorsiflexion. Methods: Thirty one persons with <10° of passive ankle dorsiflexion participated in this study. We excluded persons with acute ankle injury within six months prior to study onset, a history of ankle fracture, leg length discrepancy greater than 2 cm, no history of neurological dysfunction, or trauma affecting the lower limb. The specifications of the FMV motor were as follows: a fixed frequency (fast wave: 150 Hz) and low amplitude (0.3–0.5 mm peak to peak) of vibration; the motor was used to release the medial gastrocnemius for 15 minutes. Each participant completed three trials for 10 days; a 30-second rest period was provided between each trial. Medial gastrocnemius architectural parameters [muscle thickness (MT), fiber bundle length (FBL), and pennation angle (PA)] were measured via ultrasonography. Results: MT significantly decreased after FMV application (p < 0.05). FBL significantly increased from its baseline value after FMV application (p < 0.05). PA significantly decreased from its baseline value after FMV application (p < 0.05). Conclusion: FMV application may be advantageous in reducing medial gastrocnemius excitability following a decrease in the amount of contractile tissue. Furthermore, FMV application can be used as a stretching method to alter medial gastrocnemius architecture.

Background: Patients with stroke may show impaired balance due to the limited range of motion of the ankle resulting from abnormal soft tissues surrounding the ankle joint. Changes in the viscoelasticity of soft tissues and decreased mobility of the ankle impair the balance and lead to problems in the daily life of patients with stroke. Joint mobilization and stretching are effective methods of improving balance by increasing the viscoelasticity of soft tissues and range of motion of the ankle. Objectives: To effects of ankle joint mobilization and calf muscle stretching on balance in patients with stroke. Design: A randomized controlled trial. Methods: A total of 20 patients with stroke were randomly assigned into two groups. The joint mobilization group (JMG) underwent anteroposterior joint mobilization of the talocrural joint, while the stretching group (SG) received calf muscle stretching. Functional reach test (FRT), berg balance scale (BBS), and timed up and go test (TUG) were used to assess balance. Results: The FRT, BBS, and TUG results significantly improved in the JMG and SG after invention (P<.05). However, the improvements were greater in the JMG group than those in the SG group (P<.05). Conclusion: Joint mobilization was an effective intervention to improve soft tissue performance and range of motion of the ankle, thereby improving balance in patients with stroke.

Paid search advertising is the most popular online advertising format, and many large firms allocate a considerable amount of their advertising budget to it. In contrast, small and medium-sized firms have a limited advertising budget that potentially forces them to experience the ineffectiveness of paid search advertising. In this study, we identify the various paid search advertising strategies that even small and medium-sized firms can implement and examine the effect of the different advertising strategies on the number of clicks as a primary advertising performance measure. Using the data regarding keyword advertising from a search engine, we find that advertisers can increase the number of clicks not only by increasing their bids, but also by optimal keyword selection, targeting, and active advertisement management. Our findings provide a practical insight that there are many other advertising strategies for the managers to utilize beyond budget efficiently.

여러 센서를 이용한 구조물의 구조 응답을 모니터링하는 사례가 증가하고 있다. 그러나 비용과 관리 문제로 인해 제한된 센서만이 구조물에 설치되어 일부의 구조 응답만을 수집하는 경우가 대부분이다. 이는 구조물의 전체 거동을 분석하는데 장애요소로 작용하게 된다. 따라서 제한된 센서를 이용해 센서가 설치되지 않은 위치에서의 응답을 신뢰할 수 있는 수준으로 예측하는 기술이 필요하다. 본 연구에서는 제한된 정보를 이용해 저층 건물 구조물의 지진 응답을 예측하는 해석적 연구를 수행한다. 활용 가능한 응답 정보는 1층과 최상층의 가속도 응답만을 사용할 수 있다고 가정한다. 두 정보를 이용하면 구조물의 1차 고유진동수를 얻을 수 있다. 1층 가속도 정보는 구조물의 가력 정보로 활용한다. 최상층의 가속도이력응답에 대한 오차와 대상 구조물의 1차 고유진동수 오차를 최소화하는 구조물의 질량과 강성 정보를 유전자알고리즘을 이용해 예측하는 기법을 제시한다. 제약조건은 고려하지 않는다. 탐색공간을 의미하는 설계변수의 범위를 결정하기 위해 인공신경망 기반의 파라미터 예측기법을 제시한다. 또한 유전자알고리즘을 통해 얻게 되는 해를 개선시키기 위해 앞서 언급한 인공신경망을 활용한다. 제시한 기법을 검증하기 위해 5층 구조물 예제를 사용한다.

Consumers want to express their original unique personality, and even are willing to endure high expenses in order to do this. One noticeable strategy in the market, used by companies to suit for this consumer sentiment, is that of employing limited edition marketing and limited free gifts. This study investigated the effects of limited free gifts on consumer response. Specifically, the present study examined how the need for uniqueness moderated the effects of limited free gifts on brand commitment and attitudes. The online survey method was used to gather the data and a total of 224 data were used to analyze data. The results of the research were as follows. The findings revealed four dimensions of limited free gifts: scarcity/specialty, not for sale, complementarity, and risk. Complementarity positively affected brand commitment, while all four dimensions of limited free gifts positively influenced brand attitude. In addition, the need for uniqueness was proven to be the strongest variable which positively influenced brand commitment and attitudes. Also, when the need for uniqueness was applied as a moderating variable, depending on the levels of the need for uniqueness, the effects of riskiness on the consumer’s response were shown to be different. The findings of this study infer various academic and practical applications.

Recent focus on wastewater treatment includes energy-saving and renewable energy generation for energy-independence of water infrastructures. Aeration and pumping in biological wastewater removal processes account for nearly 30-60% of the total electricity cost in real wastewater treatment plants. In this study, the performance and microbial characteristics were investigated in sequencing batch reactor under typical oxygen and oxygen limited condition. Under typical DO (7.55±0.99 mg/L) and low DO (0.23±0.08 mg/L) conditions, COD removal was stable over 91 % during SBR operation. Ammonia removal efficiency was reduced from 95.6 % to 89.2 % when DO concentration was dropped sharply. Phosphorus removal efficiency also reached 77% at oxygen-limited condition. The results indicated that removal efficiency both ammonia and phosphorus was influenced by DO condition. Microbial analysis revealed that Proteobacteria and Bacteroidetes at phylum level was dominant in typical DO and low DO conditions and DO concentration did not much affect phylum distribution. Population decrease of genera of nitrifying bacteria(Dokdonella) and Dechloromonas spp. affect removal efficiency of nitrogen and phosphorus at low DO condition.

서평

The purpose of this study was to assess the changes in balance and proprioception of adults with limited ankle joint dorsiflexion, after the application of talocrural joint mobilization. The subjects of this study included 23 college students in their twenties with limited ankle joint dorsiflexion. The students were randomly assigned to the ankle joint mobilization group (AJMG, n=12) and the control group (CG, n=11). After 2 weeks of intervention using grade III talocrural joint mobilization in the anterior-posterior movement, the balance and proprioception of the subjects were assessed. Static/dynamic balance capabilities and ankle proprioception were analyzed using paired t-test and independent t-test. The dynamic balance and proprioception of AJMG were significantly improved after intervention (p<.05), In the comparison between the groups after the intervention, the dynamic balance and proprioceptive sense of AJMG were significantly improved compared to the control group (p<.05). This study suggests that AJMG can help improve the dynamic balance and proprioception.

본 연구는 산림, 하천, 자연 녹지 등 자연생태환경과 격리된 도심 속의 생태적 패치를 분석하고 이해하여 생태적 가치가 높은 생태 환경을 조성하는 방안을 모색해 보고자 실시하였다. 분석 대상지역은 도심 속의 생태적 패치로 다양한 입지 조건으로 조성되어 활용되고 있는 국립과천과학관(경기도 과천시 상하벌로 110일원) 일대를 중심으로 선정하였다. 생태적 패치(patch) 입지별 4개의 구역으로 구분하였고 각 조사 구역 별 결과에서 곤충상은 Ⅰ구역에서 61과 135종, Ⅱ구역에서 31과 46종, Ⅲ구역에서 31과 42종, Ⅳ구역에서 13과 14종 등으로 구분되었다. 전체 조사구역의 군집 분석 결과, 다양성 지수 4.30, 종풍부도 22.74, 균등도 0.84 등으로 구분되었다. 조사 결과, 수환경과 키 작은 수목을 중심으로 하고 경작 및 원예가 재배되는 Ⅰ구역에서 종 조성이 다양하게 분포하였고 소규모 생태적패치를 조성할 경우 수환경과 원예화원, 소규모 경작지 등이 분포할때 종 다양성이 높고 생태적으로 안정된 양상이 될 것으로 기대된다.

서평

Background:Research efforts to improve the pulmonary function of people with limited chest function have focused on the diaphragmatic ability to control breathing pattern. Real-time ultrasonography is appropriate to demonstrate diaphragmatic mechanism during breathing.Objective:The purpose of this study was to investigate the effects of diaphragmatic breathing training using real-time ultrasonographic imaging (RUSI) on the chest function of young females with limited chest mobility.Methods:Twenty-six subjects with limited chest mobility were randomly allocated to the experimental group (EG) and control group (CG) depending on the use of RUSI during diaphragmatic breathing training, with 13 subjects in each group. For both groups, diaphragmatic breathing training was performed for 30-min, including three 10-min sets with a 1-min rest interval. An extra option for the EG was the use of the RUSI during the training. Outcome measures comprised the diaphragmatic excursion range during quiet and deep breathing, pulmonary function (forced vital capacity; FVC, forced expiratory volume in 1-sec; FEV1, tidal volume; TV, and maximal voluntary ventilation; MVV), and chest circumferences at upper, middle, and lower levels.Results:The between-group comparison revealed that the diaphragmatic excursion range during deep breathing, FVC, and middle and lower chest circumferences were greater at post-test and that the changes between the pretest and post-test values were greater in the EG than in the CG (p<.05). In addition, the subjects in the EG showed increased post-test values for all the variables compared with the pretest values, except for TV and MVV (p<.05). In contrast, the subjects in the CG showed significant improvements for the diaphragmatic excursion range during quiet and deep breathings, FVC, FEV1, and middle and lower chest circumferences after the intervention (p<.05).Conclusion:These results indicate that using RUSI during diaphragmatic breathing training might be more beneficial for people with limited chest mobility than when diaphragmatic breathing training is used alone.

Two dimensional finite element method with quadrilateral basis functions was applied to the spherical high order filter on the spherical surface limited area domain. The basis function consists of four shape functions which are defined on separate four grid boxes sharing the same gridpoint. With the basis functions, the first order derivative was expressed as an algebraic equation associated with nine point stencil. As the theory depicts, the convergence rate of the error for the spherical Laplacian operator was found to be fourth order, while it was the second order for the spherical Laplacian operator. The accuracy of the new high order filter was shown to be almost the same as those of Fourier finite element high order filter. The two-dimension finite element high order filter was incorporated in the weather research and forecasting (WRF) model as a hyper viscosity. The effect of the high order filter was compared with the built-in viscosity scheme of the WRF model. It was revealed that the high order filter performed better than the built in viscosity scheme did in providing a sharper cutoff of small scale disturbances without affecting the large scale field. Simulation of the tropical cyclone track and intensity with the high order filter showed a forecast performance comparable to the built in viscosity scheme. However, the predicted amount and spatial distribution of the rainfall for the simulation with the high order filter was closer to the observed values than the case of built in viscosity scheme.