간행물
Journal of Biomedical Research
- 발행기관 충북대학교 동물의학연구소
- 자료유형 학술지
- 간기 계간
- ISSN 1976-7447 (Print)2287-7363 (Online)
- 수록기간 2000 ~ 2015
- 주제분류 의약학 > 수의학 의약학 분류의 다른 간행물
- 십진분류KDC 528DDC 636
권호리스트/논문검색
Vol. 9 No. 2 (2008년 6월) 8건
1.
2008.06
구독 인증기관 무료, 개인회원 유료
4,000원
2.
2008.06
구독 인증기관 무료, 개인회원 유료
This study investigated the frequency and distribution of canine patellar luxation (PL) in Bucheon city during January 2003 to December 2006. The 144 dogs with PL were analyzed according to grade, breeds, sex, age, body weight, and existence of concurrent cranial cruciate ligament rupture. Small breed including Yorkshire Terrier (31.65%), Maltese (33.09%) and Poodle (12.23%) had higher distribution of PL. Especially Yorkshire Terrier and Maltese had higher population of PL compared with other breeds. Most of them were diagnosed as II-III grade PL, and only a few dogs had grade I and grade IV PL. Small breed of body weight 2-3 kg (38.88%) had higher population of PL, and most of them were intact female (46.52%) and castrated male (38.19%) dogs. This study showed that clients recognized the necessity of the operation for dogs with PL well when the dogs are 6 months and 3 year-old, and have II-III grade PL. The reason that body weight of 2-3 kg had higher percentage of PL is related to the breeds. In analysis, intact female and castrated male dog had higher distribution of PL. The occurrence of concomitant cranial cruciate ligament rupture was 11%. Patellar luxation is therefore considered having an influence on cranial cruciate ligament rupture.
4,000원
3.
2008.06
구독 인증기관 무료, 개인회원 유료
Saline-tab water (2.5 L) with 0, 2.5, 5, and 10% saline solution contaminated by P. aeroginosa or S. aureus, was electrolyzed with constant electrical current of 2A or 4A for different time durations (1, 2, 4, 8, and 16min). The electrolysis with 2A-4min showed disinfection effect against P. aeroginosa of 105 CFU/㎖ in all saline concentrations. When the electrical current was raised to 4A, P. aeroginosa of 106 CFU/㎖ was disinfected in 4 min. S. aureus of 105 CFU/㎖ was disinfected with 2A-2 min in all saline concentrations. S. aureus of 106 CFU/㎖ was completely disinfected with 2A-8 min. To compare the effect of constant current electrolysis with that of intermittent current electrolysis, solution contaminated with P. aeroginosa of 106 CFU/㎖ was electrolyzed with several pairs of intermittent current of 2A for 2 min followed by 2min pause. Disinfecting effect of intermittent electrolysis was very similar to the constant current electrolysis without pause in 16 min. The present study demonstrated that the direct electrolyzing process with no septum membrane is a convenient and economic sterilization method.
4,000원
4.
2008.06
구독 인증기관 무료, 개인회원 유료
Anti-inflammatory effects of ethanolic extract of Angelica gigas (EAG 50, 150, and 500 mg/kg) were investigated in thermal burn-paw edema model. Immersion of rat hind legs into 48.5℃ water for 50 scincreased the leg volume by 0.46-0.55 ml. EAG attenuated not only the paw volume in a dose-dependent manner, but also blood lymphocyte counts and interleukin-6 level increased by burns, without influence on the level of tumor-necrosis factor-α. Moreover, EAG reduced alkaline phosphatase level, a parameter of hepatic injury, which was increased by thermal burns. The results indicate that EAG attenuates inflammatory aymptoms induced by thermal burn and EAG or its conmarin derivatives could be a promising anti-inflammatory drug candidate in inflammation diseases.
4,000원
5.
2008.06
구독 인증기관 무료, 개인회원 유료
Jin-Joo Hue, Ki-Nam Lee, Myak Miga, Bong Su Kang, Sang Yoon Nam, Byeongwoo Ahn, Young Won Yun, Beom Jun Lee
Phytic acid (PA) is a naturallu occurring polyphosphorylated carbohydrate that is present in substantial amounts in almost all plants and mammalian cells. Recently PA has received much attention for its role in anticancer activity. We investigated the preventive effect of PA on the formation of colonic aberrant crypt foci (ACF), a preneoplastic lesion, induced by azoxymethane (AOM). After acclimation for one week, six-week old male ICR mice were fed on the AIN-93G purified diet and PA (0.5% or 2% PA in water) for 8 weeks. The animals were treated with azoxymethane (AOM, 10 mg/kg b.w.) three times (0, 1, and 2 weeks) to induce colonic aberrant crypt foci (ACF). After sacrifice, the total numbers of aberrant crypts (AC) and ACF in colonic mucosa were counted after staining with methylene blue. Blood and serum were analyzed with a blood cell differential counter and an automatic serum analyzer. AOM treatment without PA induced the total numbers of 85.7 ± 12.9 and 115.2 ± 19.9, respectively. PA at the dose of 2% AC/colon by PA at the dose of 0.5% were 73.4 ± 12.9 and 115.2 ± 19.9, respectively. PA at the dose of 2% significantly decreased the ACF and AC numbers to 56.5 ± 14.6 and 95.4 ± 17.2, respectively (p＜0.01). PA at the doses of 0.5 and 2% decreased the numbers of ACF and AC/colon in a dose-dependent manner. Although some parameters in blood counts and serum chemistry were changed compared with the control, no specific toxicity was found. Theses findings suggest that phytic acid can be a chemopreventive agent for colon carcinogenesis resulting from inhibition of the development of ACF in ICR mice.
4,000원
6.
2008.06
구독 인증기관 무료, 개인회원 유료
The acute and subacute toxicities of copper sulfate were evaluated in zebrafish (Brachydanio rerio). Dipping of fishes for acute toxicity was performed for a period of 24 h, and TLm24h value (median tolerance limit = LC50) was 1.36 ppm. Clubbing of gill filaments due to severe epithelial hyperplasia of gill lamella were oberved. And epithelial edema, fusion and necrosis of renal tubules were presented. The most significant change was mild epithelial hyperplasia of gill lamella in subacute toxicity test which fishes were exposed to 0.15 ppm of copper sulfate for 1 week.
4,000원
7.
2008.06
구독 인증기관 무료, 개인회원 유료
3,000원
8.
2008.06
구독 인증기관 무료, 개인회원 유료
A 13-year-old, male mixed breed dog was presented to Veterinary Medical Center, Chungbuk National University for diagnosis and treatment of enlarged mass in right inguinal region. On hematological test, monocytes and neutrophils were slight increased, but other hematological values were normal. On radiological finding, opacity and size of mass in right inguinal region were increased. The mass and testis were removed surgically. Removed mass was oval-shpae and bulky with 5.6×7.6×5.2 cm. Histopathological finding of the mass revealed large and round to polyhedral cells and it was diagnosed as malignant seminoma. That was diffuse type seminoma near to malignant tumor without metastasis. During the follow-up for 13 months, patient showed normal contition without recurrence.
4,000원
