이 연구는 한국해양과학기술원 동해연구소 독도전문연구센터가 동해의 바닷속 펼쳐진 거대한 독도의 해양영토를 밝히고 그 가치를 찾아 한국의 영토로서 확고한 주권확립과 이용관리에 기여하고 있으며, 과학연구 활동으로 많은 성과를 이루어내고 있기 때문에 독도 해양과학연구 성과를 중심으로 홍보현황과 활성화 방안에 대하여 조사와 분석을 한 것이다. 이 독도전문연구센터는 2006년도에 설립되어 올해 16년째 독도 해양과학연구를 꾸준 히 하고 있으며, 축적된 연구 성과에 대하여 홍보를 하였다. 이러한 독도 해양과학연구 성과의 홍보 방법으로는 학술논문, 학술활동, 특허, 서적출간, 언론홍보, 전시회 및 학술행 사, 독도관련 화보집, 총서와 독도체험시스템 등이 있다. 독도전문연구센터의 독도 해양과 학연구 성과의 홍보현황을 보면 2006년부터 2020년까지 학술논문은 82편, 학술발표 226편, 특허 11건, 서적 35종, 언론홍보 1158건, 전시회 32건, 학술행사(워크숍, 세미나, 심포지엄 등) 227건, 대중강연 107건, 견학(방문) 791건, 자료제공 226건 등 약 3천건 정도로 집계되었다. 독도 시민단체와 반크 등 일반인의 독도 홍보활동은 많이 이루어지고 있지만, 독도 해양과학 연구자들의 독도 성과와 홍보에 관한 것은 아직 충분치 않은 실정이 라고 할 수 있다. 그래서 본고에서는 다음과 같은 활성화 방안을 제시하였다. 첫째, 새로운 해양, 해저지형 표기에 있어서 동도, 서도 외 89개 부속 섬의 전체 바위명칭 부여 및 지도, 리플릿 제작 배포가 필요하다. 둘째, 독도 이용개발에 있어서 육상의 경우에는 자연환 경에 의한 풍화작용 등의 영향으로 바위가 훼손되는 현상을 지속적으로 모니터링 해야 한다. 셋째, 독도 해양 및 환경자료 활용을 확대하여 독도 통합관측시스템을 구축 및 운영하 여 실시간 서비스 제공도 지속적이어야 한다.

본 연구는 중학생들의 대인관계능력을 향상시키기 위한 접근으로서 스포츠 참여와 신체적 자기 개념 및 대인관계능력에 대한 인과관계를 검증하여 중학생들의 대인관계능력을 향상시키기 위한 스포츠 참여의 역할과 건전한 자기개념의 인식을 마련하는데 그 목적이 있다. 이를 위해 C도에 거주하고 있는 중학생들을 모집단으로 설정하고 편의표본추출 방법을 이용하여 총 400명을 대상으로 자료를 분석하였다. 설문지는 확인적 요인분석(CFA)을 실시하여 타당성을 확보하였으며, 자료 분석은 구조방정식 모형분석(SEM)을 실시하였다. 연구결과는 다음과 같다. 첫째, 중학생들의 스포츠 참여는 대인관계능력에 직접적인 영향을 미친다. 둘째, 중학생들의 스포츠 참여는 신체적 자기개념에 직접적인 영향을 미친다. 셋째, 중학생들의 신체적 자기개념은 대인관계능력에 직접적인 영향을 미친다. 넷째, 중학생들의 신체적 자기개념은 스포츠 참여와 대인관계능력 사이에서 부분매개역할을 한다.

외국 연구자들이 미국에서 발간되는 학술지에 발표하는 독도관련 연구는 일반적으로 생각하는 것처럼 깊이가 있거나 이론이 정연하지는 않는 것 같다. 이들의 연구는 독도의 영유권 다툼을 다루거나 국제해양법상 일반적인 섬의 지위를 다루면서 독도를 연구하고 있다. 즉, 독도가 해양법상 어떠한 해양관할수역을 갖는지, 혹은 해양경계획정에서 어떠한 효과를 갖는지가 연구의 대상이다. 독도 영유권과 관련하여서는 한국의 주장을 지지하는 학자와 일본의 주장을 지지하는 학자로 나누어지는데, 이들은 대체로 한국과 일본의 정부 입장이나 학자들의 연구를 바탕으로 논거를 마련하고 있다. 그리고 로스쿨 학생들과 같은 연구자들은 심도있는 분석을 하지 않고 선행 연구자들의 주장을 그대로 답습하는 모습을 보이고 있다. 이들이 대체로 한국에 유리한 주장을 하고 있는 것은 나름대로 위안거리라고 하겠다. 한편 독도의 해양법상 지위는 제한적인 것으로 판단하고 있는데, 대체로 배타적 경제수역이나 대륙붕을 갖지 못하는 바위섬으로 취급하고 있으며 또한 일본과의 해양경계획정에서 아무런 효과도 갖지 못할 것으로 전망하고 있다. 한편 외국 연구자들은 독도 영유권 문제를 연구함에 있어 대체로 영어로 된 인터넷 자료를 많이 인용하며 연구하고 있는데, 특이한 점은 일본 주장을 지지하는 연구자는 일본 정부의 주장을 인용하고 있음에 반하여 한국의 입장을 지지하는 연구자는 개인이 운영하는 인터넷 사이트를 인용하고 있다는 것이다. 그리하여 우리의 주장을 영문으로 소개하는 사이트의 적극적인 활용이 요구되고, 또한 한글로 발표된 독도 관련 연구결과물을 외국어로 소개하는 작업도 활발하게 진행할 필요가 있다고 본다.

본 연구는 철근콘크리트 단층 구조물의 구조 부재 위치에 대한 비파괴검사법을 이용한 추정 신뢰도를 알아보기 위해 기둥, 벽체, 보 및 슬래브로 구성된 실험체를 제작하고, 기존 추정식과 비교 과정에서 정확한 분석을 위해 오차율 비교와 모평균 구간 추정을 사용하여 통계적 접근을 통한 신뢰성을 분석하고자 한다. 그 결과, 초음파속도법을 이용하여 압축강도를 추정한 결과와 코어시험 결과를 비교한 전체 평균 오차 율은 18.8%, 반발경도법을 이용하여 압축강도를 추정한 결과와 코어시험 결과를 비교한 전체 평균 오차율은 20.1%가 도출되어 현장 적용성을 확인하였다. 그리고 부재별 신뢰성 부분에서 초음파속도법과 반발경도법을 이용하여 신속하고 효율적인 구조물 안전진단을 하기 위해서 각각 벽체 부재와 보 부재를 중심으로 압축강도 추정 시 신뢰도 높은 결과를 도출되는 것을 확인하였다.

최근 건축물 진단기법 관련하여 관심이 높아지고, 건축물 안전진단 수요가 증가하고 있다. 국토교통부(2018)의 통계에 의하면 30년 이상 된 노후화된 건축물은 전국에 약 267만 동으로, 신속하고 정확한 안전진단을 할 수 있는 시스템 구축이 요구되는 실정이다. 본 연구는 비파괴 검사법인 초음파속도법, 반발경도법 및 충격법을 이용하여 철근콘크리트 구조물의 성능평가를 위하여 정립된 기법을 시스템화하여 구현하는 것 목표이다.

최근 건축물 붕괴사고 빈도수가 증가하면서 안전진단에 대한 수요가 증가하고, 신뢰도 높은 안전진단기법에 대한 요구가 확대되고 있다. 국토교통부(2018) 자료에 따르면 노후건축물 수에 비해 안전진단관련 전문기관이 부족한 실정이다. 본 연구에서는 초음파속도법을 이용한 압축강도 추정 값과 코어 시험을 이용한 콘크리트 압축강도 측정값을 비교하여 추정오차율 비교와 신뢰도 구간 추정을 하고, 최소인원으로 신속하게 효율적인 구조물 안전진단 기법을 제안하는 것을 목표로 한다.

In this study, we analyze the policy related to building safety diagnosis and maintenance management and suggest improvement direction of system for building diagnosis. The US has various test methods and laws and regulations standardized on wide territory, so it is excellent in responding to changes in regulations. In the UK, the technology of the building diagnosis related field is advanced through systematic efforts of diagnosis and maintenance of the building. Therefore, it is necessary to establish and revitalize regulations related to building diagnosis and maintenance management, to revise the laws and regulations of related institutions, and to systematically cultivate manpower through specialized agencies related to diagnosis and maintenance.

Korea represents high suicide rate by poisoning. Especially, since a lot of people died by high concentrated paraquat which has extremely high fatality rate, paraquat sales were prohibited in 2012. We investigated to find out how the prohibition of sales affected occurrence of pesticide poisoned patients and what kinds of influences did it have for severity and death rate. By targeting patients who visited emergency room by pesticide poisoning from 2010 to 2014, we researched insecticides poisoned patients and herbicidal poisoned patients grouped into 9 categories. Before and after 2012, We compared A term (2010, 2011) and B term (2013, 2014)’s pesticide occurrence, especially distribution of herbicide occurrence and compared hospitalization rate, hospitalization period, length of stay in ICU (Intensive Care Unit), severity, and death rate. The number of insecticide patients was 219 (37.4%) and the number of herbicide patients was 367 (62.6%) who visited emergency room in five years and the rate was similar every year. In case of paraquat, there was 70.5% decrease by 105 people for A term and 31 people for B term and increase of double for glyphosate, glufosinate, and other herbicides. The death rate was decreased but hospitalization was increased. There weren’t any difference of rate in ICU admission, intubation and ventilator therapy. By prohibition of using paraquat, the death rate by pesticide poisoning was decreased. However, patients who poisoned by other herbicides were increased, so hospitalization rate increased and there weren’t any difference at patient’s severity rates.

Background : Scopolamine induces cholinergic dysfunction and oxidative stress, and the impairment of memory function. Therefore, oxidative stress and cholinergic dysfunction are important role of the brain pathology of amnesia. In this study, we investigated the impact of Safflower seed against oxidative stress and cholinergic dysfunction on scopolamine-induced amnesic mice. Methods and Results : Mice were orally pretreated with safflower seed (100 ㎎/㎏ body weight) or vehicle for 7 days, and scopolamine (1 ㎎/㎏ body weight) was injected intraperitoneally, 30 min before the behavior tests such as T-maze and novel objective recognition test on first day. To evaluate learning and memory function, the Morris water maze task was performed for 5 days, consecutively. The results showed that spatial perceptive ability and novel object recognition was significantly increased by preadministration of safflower seed compared with scopolamin-induced control mice in the behavior tests. Consistently, immuno blot revealed the elevated expression of superoxide dismutase 1 in the safflower seed pretreated mice, compared to the control mice. Moreover, protein expression of acetylcholinesterase was decreased in safflower seed pre-treated group. Conclusion : Subsequently, our results suggests that the Safflower seed extract improved memory impairment through inhibition of cholinergic dysfunction and oxidative stress.

Background : Excess alcohol consumption can lead to alcoholic liver damage and gastritis. Korean thistle (Cirsium japonicum var. maackii) has been reported that it’s administration protective from liver from lipid accumulation and toxicity. Also, Korean dandelion (Taraxacum coreanum Nakai) has been traditionally used for treating various inflammation-related diseases including ethanol-induced gastritis. In this study, we aimed to determine whether the combination treatment of Korean thistle and Korean dandelion could regulate alcoholic liver damage and gastritis in mice. Methods and Results : Seven-week-old mice were treated with ethanol (5 g/㎏ of body weight) by gavage every 12 h for a total of three doses to induce acute liver damage and gastritis. Ethanol extract of Korean thistle, Korean dandelion or combination was gavaged simultaneously with ethanol for three doses. The results showed that the combination treatment of Korean thistle and Korean dandelion significantly inhibited alcohol-induced increase of serum alanine transaminase and aspartate transaminase levels, liver weight, and hepatic caspase-3 expressions. Hepatic histopathological changes induced by alcohol were also remarkably improved by the combination treatment. The combination treatment inhibited alcohol-induced Morphological changes of gastritis and attenuated the expressions of pro-inflammatory protein, such as inducible nitric oxide synthase. Conclusion : The results of our study suggest that the combination treatment of Korean thistle and dandelion may simultaneously alleviate acute alcohol-induced gastritis and liver damage.

The number of deteriorated buildings is increasing every year, and the number of accidents is increasing due to the lack of timely diagnosis, maintenance, and reinforcement. The number of specialized institutions that can diagnose this is limited compared to the number of deteriorated buildings, and a lot of time and resources are invested in the absence of advanced diagnostic techniques based on the evaluation factors of deteriorated buildings. Therefore, it is necessary to build an improved building diagnosis platform by examining the reliability of existing diagnostic evaluation factors for accurate and rapid building diagnosis.

Background : In the previous results, antidepressants and anxiolytic Effects were reported from the leave extracts of Valeriana fauriei. The major compounds of leave were valeranone and valerianate. The purpose of this study was to the investigation of nerve related bioassay correlation and of low-molecular’s chemical constituents from different parts of V. fauriei. Moorover, we proposed the biochemical pathways from the low molecular’s chemical constituents of V. fauriei. Methods and Results : First, in order to investigate the chemical constituents of V. fauriei, we were analyzed the references of V. fauriei. And, we were analyzed the low molecular’s chemical constituents by using GC-MS from extracts of different parts from V. fauriei. As a result, 39 compounds, which are (+)-8-hydroxypinoresinol, (+)-hydroxipinoresinol, 2S (-)hesperidin, 4a, 10a-epoxy-aromadendrane, 6-methylapigenin, 8-hydroxypinoresinol, acetoxy- valerenic acid, acetylvalerenolic acid, actinidine, anismol A, baldrinal, dihydrode hydrodiconiferyl alcohol 9-isovalerate, E- (-)-3,4-Epoxyvalerenal, E- (-)-3,4-Epoxyvalerenyl acetate, E-valerenyl acetate, E-valerenyl isovalerate, hydroxy- valerenic acid, linarin, mononorvalerenone, orientalol C, pinorespiol, pinorespiol, spatulenol, valdiate, valeranone, valerenal, valerenic acid, valerenol, valerenyl hexanoate, valerenyl n-valerate, valerianine, valtrate, volvalelactone A, volvalelactone B, volvalerenone A, volvatrate A, volvatrate B, Z-valerenyl acetate, Z-valerenyl isovalerate. were reported as the chemical constituents of V. fauriei. And also, hexadecane, propanoic acid, 3-β-hydroxypregn-5-ene-20-carb oxylic acid, spiro [cyclopropane-1,8’ (1H’) methano, from flower, cis-5,8,11,14,17-eicosapentaenoic acid, 1,1-Dimethyl-1-silacyclobutane, oleamide, 3-β-hydroxypregn-5-ene-20-carboxylic acid, per (trimethylsilyl)-D-lyxose from leaf, N- [(-)-jasmonoyl]- (S)-glutamic acid from stem, 9-octadecenamide, 1-ethyl-4- phosphorinanone, thiosemicarbazone, raffinose from root, were detected. We proposed the biochemical pathway from the chemical constituents of V. fauriei. Conclusion : The results of our study suggest that the proposal biochemical pathway of V. fauriei will be useful in the study of correlation of nerve related bioassay.

Background : Osteoarthritis is an inflammatory disorder related with oxidative stress and apoptosis leading to cartilage damage. Recently, Cirsium japonicum var. maackii (CJM) was reported to play a protective role in various inflammatory response. However, the role of CJM in cartilage degeneration and osteoarthritis progression is still unknown. Therefore, this study aims to investigate the protective effect of CJM in a animal model of osteoarthritis and cartilage degradation. Methods and Results : First, in order to determine active ingredient contents of CJM, we were carried out total polyphenolic content and total flavonoid content analyses. As a result, dried aerial parts of CJM were found to contain 149.2 ± 24.1 ㎎·GAE/g dry weight and 27.9 ± 2.0 ㎎·NE/g dry weight in boiling water extraction. Also, the HPLC analysis of CJM showed major compounds identified as cirsimarin and cirsimaritin. In addition, CJM protected against osteoarthritic cartilage destruction in an osteoarthritis mouse model induced by destabilization of the medial meniscus, as demonstrated by histopathological analysis. Conclusion : The results of this study demonstrate that CJM may protect against the osteoarthritis and cartilage destruction. Further study is needed to identify the mechanism for their improvement effects of osteoarthritis and cartilage destruction.

Background : Oxidative stress and inflammatory response are important features of the brain pathology of Alzheimer's disease. Therefore, the purpose of this study was to the antioxidant activity and biochemical characterization of safflower seed. Moreover, we investigated the impact of Safflower seed on scopolamine-induced memory impairment in mice. Methods and Results : First, in order to determine active ingredient contents of safflower seed extract, we were carried out total phenol content and total flavonoid content analyses. As a result, dried safflower seed were found to contain 35.4 ± 0.4 ㎎·GAE/g dry weight and 45.3 ± 7.5 ㎎·NE/g dry weight in boiling water extraction. Also, the major compounds of safflower seed from HPLC analysis were identified as serotonin and serotonin derivatives [N- (p-coumaroyl)serotonin and N-feruloylserotonin]. In addition, the antioxidant activity of safflower seed showed IC50 values of 331.4 and 168.2, respectively, against DPPH and ABTS in vitro. Finally, with regard to the memory improvement activity, the administration of Safflower seed extract significantly restored memory impairments induced by scopolamine in the behavior tests such as novel object recognition and Morris water maze test. Conclusion : The results of our study suggest that the safflower seed extract possess potent memory improvement activity and are also a good source of natural antioxidants. Further study is needed to identify the mechanism responsible for their memory improvement activity.

Background : Rehmannia glutinosa root (R. root) has been used as traditional medicine, and is important resource for natural medicines and functional foods. In Korea, various varieties of Rehmannia glutinosa have been developed, and these have various characteristics depending on the variety. Therefore, this study was performed to compare the antioxidant and anti-aging activities of R. root extracts with various varieties (Jihwang 1ho, Goryeo, Daegyeong, Gogang, Togang, Dagang, Wongang, Yeongang, Hwanggang, and Segang). Methods and Results : R. roots were extracted by reflux extraction method with 70% ethanol-water solution at 40℃, and their extracts were used for total phenolic contents, antioxidant and anti-aging activities. The total phenolic content, ABTS and DPPH radical scavenging activities were highest in Yeongang, and these values were 11.50 ㎎/g, 9.37 ㎍/g TEAC, and 7.13 ㎍/g TEAC, respectively. However, the anti-aging activity on human dermal fibroblast cells treated with doxorubicin was higher in Segang, Dagang, and Goryeo than other varieties, and their senescence ratios were measured at 50.66, 57.16, and 61.36% when treated at 200 ㎍/㎖, respectively. The total phenolic content and DPPH radical scavenging activity were negatively correlated with anti-aging activity. Conclusion : These results indicated that the antioxidant and anti-aging activities of R. root extracts were differed according to variety of Rehmannia glutinosa, and positive correlation between anti-oxidant activities and anti-aging activity was not shown.

Background : Prepared Rehmanniae root (PRR) has been used as traditional medicine, and is one of the most important oriental herbal medicines. However, physical characteristics of PRR are not suitable for use in industry. This study was performed to suggest preparation method of PRR powder, and determine the physicochemical characteristics of PRR powder with different pre-freezing temperatures. Methods and Results : Moisture content, powder yield, particle size, bulk density, compressive stress, extraction yield, and 5-HMF content of PRR powders with different pre-freezing temperatures (-20℃, -40℃, -60℃, and -80℃) were analyzed, and correlation among these factors was determined. Powder yield increased and particle size decreased in a pre-freezing temperature-dependent manner from -20℃ to -60℃. Hausner ratio increased from 1.186 to 1.225 with decreasing temperature from -20℃ to -80℃, and compressive stress showed the opposite trend. Extraction yield and 5-HMF content were not significantly different between PRR and powder. Significant correlations were observed among pre-freezing temperature and physical characteristics (yield, particle size, hausner ratio, and compressive stress). Conclusion : These results suggest that pre-freezing temperature was important factors affecting physical characteristics of PRR powder, and the results of this study are industrially applicable to production of PRR powder.

Background : Rehmannia glutinosa root (R. root) has been used as traditional medicine, and is important resource for natural medicines and functional foods. However, R. root have catalpol which have bitterness, and undigested sugars, including stachyose, raffinose, and verbascose as main compounds, and these compounds can cause diarrhea and abdominal pain. Therefore, this study was performed to determine the changes in reducing sugar producted from undigested sugars and catalpol contents as a bitter taste compound in R. root with aging treatment conditions. Methods and Results : R. root was treated at 10 - 70℃ for 0 - 48 h, and extracted with 50% ethanol solution. Their catalpol content was analyzed using HPLC-UVD, reducing sugar content generated from undigested sugars was measured by the Nelson-Somogyi methods, and these reaction rates were calculated from their variation according to aging time and temperature. During aging treatment, reducing sugar content increased and catalpol content decreased. Their formation and degradation rates were highest at 50℃ and 30 - 40℃, and their rates were 1.89 ㎎/g·h and 23.09 - 23.33%/h, respectively. Conclusion : These results indicated that aging treatment can positively affect the sweetness and digestibility of R. root slurry. Therefore, aging treatment could be considered for improving the sensory qualities and digestibility of R. root.

This study is a case of construction after bridge demolition due to the aging of bridges operating the railway. Due to the influence of the pier vibration on the railway, the influence of the railway line, the construction period, etc., the P.B.S technique was applied to the coping pile foundation. It was completed in 5 days per 1 bridge pier by the PBS method. Since it is constructed in the dry season (from October to April) without vibration and noise, it can be installed safely on the rail rail of the pier of the bridge .

Background: Rehmanniae radix preparata (RRP) has been used as a traditional medicine and is one of the most important oriental herbal medicines. However, the physical characteristics of RRP are not suitable for use in industry. The present study was undertaken to determined the preparation method of RRP powder and the physicochemical characteristics of RRP powder by milling under different pre-freezing temperatures. Methods and Results: Moisture content, powder yield, particle size, bulk density, compressive stress, extraction yield, and 5-HMF content of PRR powders by milling with pre-freezing temperatures (−20, −40, −60, and −80℃) were analyzed, and correlation among these factors was determined. Powder yield increased and particle size decreased in a pre-freezing temperature-dependent manner from −20 to −60℃. The Hausner ratio increased from 1.186 to 1.225 with decreasing temperature from −20 to −80℃, whereas compressive stress showed the opposite trend. Extraction yield and 5-HMF content were not significantly different between RRP powder. Significant correlations were observed among pre-freezing temperature and physical characteristics (e.g., yield, particle size, Hausner ratio, and compressive stress). Conclusions: These results suggest that the pre-freezing temperature is an important factor affecting the physical characteristics of PRR powder and applicable to the industrial production of RRP powder

본 연구의 목적은 과업집중 분석법을 통한 우수 초등영어 수업의 관찰 및 분석을 통하여 효과적 인 과업조건을 파악하는데 있다. 수업 관찰 대상은 초등학교 6학년 과업 중심 수업으로 과업 중 활동을 연습(practice), 발표(presentation)와 퀴즈(quiz)의 세 단계로 나누어 과업집중도를 도출하 였다. 또한 과업조건 유형은 정보의 흐름에 따른 단방향 과업과 양방향 과업의 분류 및 과업결과 일치여부에 따른 수렴 과업과 발산 과업의 분류에 따라 과업집중도를 산출하였다. 분석 결과, 본 수업에서의 과업집중도는 비과업집중도에 비해 매우 높은 것으로 나타났다. 과업의 단계에서는 교 사 중심적 활동보다 학생 주도적 활동에서 과업집중도가 소폭 상승하였다. 과업조건별 과업집중도 에서는 단방향 과업에 집중한 비율이(43.58%) 양방향 과업에 집중한 비율(56.42%) 보다 낮았으며, 수렴 과업에 집중한 비율(69.73%)은 발산 과업에 집중한 비율(30.27%) 보다 높게 도출되었다. 언 어 기능별 과업집중도는 듣기(48.43%)가 가장 높았으며, 읽기(19.13%), 쓰기(18.28%)와 말하기 (14.16%)의 순서로 나타났다. 본 수업의 분석 결과를 바탕으로 우수한 초등영어 수업의 과업 양상 을 파악하고 추후 효과적인 과업조건을 구성하기 위한 지표로 활용할 수 있을 것이다.