The objective of this study was to prove the effect of pig slurry application with charcoal on nitrogen use efficiency (NUE), feed value and ammonia (NH3) emission from maize forage. The four treatments were applied: 1) non-pig slurry (only water as a control), 2) only pig slurry application (PS), 3) pig slurry application with large particle charcoal (LC), 4) pig slurry application with small particle charcoal (SC). The pig slurry was applied at a rate of 150 kg N ha-1, and the charcoal was applied at a rate of 300 kg ha-1 regardless of the size. To determine the feed value of maize, crude protein, dry matter intake, digestible dry matter, total digestible nutrient, and relative feed value were investigated. All feed value was increased by charcoal treatment compared to water and PS treatment. Also, the NUE for plant N was significantly higher in charcoal treatments (LC and SC) compared to PS treatment. On the other hand, there is no significant difference for feed value and NUE between LC and SC. The NH3 emission was significantly reduced 15.2% and 27.9% by LC and SC, respectively, compared to PS. Especially, SC significantly decreased NH3 emission by 15% compared to LC. The present study clearly showed that charcoal application exhibited positive potential in nitrogen use efficiency, feed value and reducing N losses through NH3 emission.

The present study was aimed to estimate the effect of ensiling period and bacterial inoculants on chemical compositions and fermentation characteristics on rye silage harvested at delayed stage. Rye (Secale cereale L.) was harvested after 20 days of heading stage (29.4% dry matter, DM). The harvested rye forage was applied with different inoculants following: applications of distilled water (CON), Lactobacillus brevis (LBB), Leuconostoc holzapfelii (LCH), or mixture of LBB and LCH at 1:1 ratio (MIX). Each forage was ensiled into 20 L mini bucket silo (5 kg) for 50 (E50D) and 100 (E100D) days in triplicates. The E50D silages had higher in vitro digestibilities of DM (IVDMD, p<0.001) and neutral detergent fiber (IVNDFD, p=0.013), and lactate (p=0.009), and acetate (p=0.011) than those of E100D, but lower pH, lactic acid bacteria (LAB), and yeast. By inoculant application, LCH had highest IVDMD and IVNDFD (p<0.05), while MIX had highest lactate and lowest pH (p<0.05). The CON and LCH in E50D had highest LAB and yeast (p<0.05), whereas LBB in E100D had lowest (p<0.05). Therefore, this study concluded that LCH application improved the nutrient digesbility (IVDMD and IVNDFD) of lignified rye silage, and longer ensiling period for 100 days enhanced the fermentation characteristics of silage compared to ensiling for 50 days.

Cymbidium is one of the most popular and economically important species cultivated as a commercial ornamental crop. The objectives of this study were to determine the appropriate electrical conductivity (EC) treatments of nutrient solution, which gives the highest spike production and quality. Three-year-old Cymbidium ‘Lovely Smile’ plants were grown in the environmentally controlled Information and Communication Technology (ICT) smart greenhouse at Seoul Women’s University. The EC of the nutrient solution was changed in three distinct stages: vegetative, flower initiation, and flower development. The EC treatments were 1-0-1 (dS·m-1, EC101), 1-1-1 (dS·m-1, EC111), 2-1-2 (dS·m-1, EC212), 2-2-2 (dS·m-1, EC222), 3-2-3 (dS·m-1, EC323), 3-3-3 (dS·m-1, EC333) and the pH was adjusted to 6.0–6.5. Pseudobulb diameter increased in the plants treated with EC 101 and EC111 compared to the plants treated with EC 2.0–3.0 dS·m-1 at the reproductive stage 28 weeks after nutrient solution treatment. Flower spike production per pot and pseudobulb showed the highest values in the plants treated with EC111 of 3.3 and 1.4, respectively. Flower spikes length was the highest in the plants treated with EC 1.0 dS·m-1 and stem thickness, number of flowers, and fresh weight were the largest in the plants with EC 1.0 dS·m-1 among the EC treatments. Flower spikes had the worst quality (e.g., plant growth and flowering quality) in the plants treated with EC 3.0 dS·m-1 among the EC treatments. Floral bud and flower development took place 1–2 weeks earlier in the plants treated with EC 101, 111, and 212 than the other treatments. Flower diameter showed the highest values in the plants treated with EC 1.0 dS·m-1 among the EC treatments and flower color showed higher L* and b* values and lower a* values in the plants treated with EC 3.0 dS·m-1 compared to EC 1.0 and 2.0 dS･m-1. Nutrient solution of EC 1.0 dS·m-1 (EC111) can be recommended to improve flower spike quality and advanced flower development of Cymbidium.

In supply chain, there are a variety of different uncertainties including demand, service time, lead time, and so forth. The uncertainty of demand has been commonly studied by researchers or practitioners in the field of supply chain. However, the uncertainty of upstream supply chain has also increased. A problem of uncertainty in the upstream supply chain is the fluctuation of the lead time. The stochastic lead time sometimes causes to happen so called the order crossover which is not the same sequences of the order placed and the order arrived. When the order crossover happens, ordinary inventory policies have difficult to find the optimal inventory solutions. In this research, we investigate the lead time distribution in case of the order crossover and explore the resolutions of the inventory solution with the order crossover.

Culturally, it is wonderful that they try to integrated their ordinary life on the earth into heavenly spiritual life through their funeral rituals and song so called Yeong-Jang-Sori as same context as in the Pacific. During life, they eat traditional bread ( Bing-Teok) and drink traditional liquor (O-Me-Gi Ssol) and wear persimmon-dyeing Gal-ot healthily and they meet each other in the heaven eternally through happy dying. We are evidently sensitive to the unique cultural heritage of the island. UNESCO’s mission is the promotion of peace amongst peoples and its cultural heritage is also dedicated to working with indigenous peoples’ on their eco-friendlly knowledge of a sustainable planet. As Jeju Island is inscribed in part as both a World Heritage Site and a UNESCO Biosphere, it is important to give due consideration to the natural and cultural heritage of the island, as seen and experienced by the islanders. As such, if there is something useful we can discuss, for example the recognition of the special relationship between Jeju islanders and sacred natural sites on the island.

As Deepfakes phenomenon is spreading worldwide mainly through videos in web platforms and it is urgent to address the issue on time. More recently, researchers have extensively discussed deepfake video datasets. However, it has been pointed out that the existing Deepfake datasets do not properly reflect the potential threat and realism due to various limitations. Although there is a need for research that establishes an agreed-upon concept for high-quality datasets or suggests evaluation criterion, there are still handful studies which examined it to-date. Therefore, this study focused on the development of the evaluation criterion for the Deepfake video dataset. In this study, the fitness of the Deepfake dataset was presented and evaluation criterions were derived through the review of previous studies. AHP structuralization and analysis were performed to advance the evaluation criterion. The results showed that Facial Expression, Validation, and Data Characteristics are important determinants of data quality. This is interpreted as a result that reflects the importance of minimizing defects and presenting results based on scientific methods when evaluating quality. This study has implications in that it suggests the fitness and evaluation criterion of the Deepfake dataset. Since the evaluation criterion presented in this study was derived based on the items considered in previous studies, it is thought that all evaluation criterions will be effective for quality improvement. It is also expected to be used as criteria for selecting an appropriate deefake dataset or as a reference for designing a Deepfake data benchmark. This study could not apply the presented evaluation criterion to existing Deepfake datasets. In future research, the proposed evaluation criterion will be applied to existing datasets to evaluate the strengths and weaknesses of each dataset, and to consider what implications there will be when used in Deepfake research.

This study attempted to interpret the meaning of the U.S.-China hegemony competition based on liberal theory, and predicted future U.S.-China relations by analyzing the hegemony confrontation between the U.S. and China. During the U.S.-China hegemony competition, countries around China, which are directly threatened by China, were divided into continental and maritime national groups, and the characteristics, concerns, and responses of those countries were considered. It proposed a new maritime-new continent global bridge economic block system, suggested strengthening economic cooperation, technical cooperation, cultural cooperation and liberal international order as its effectiveness, and suggested the need of a new international order during the Fourth Industrial Revolution.

Oral squamous cell carcinoma (OSCC) metastasis is characterized by distant metastasis and local recurrence. Combined chemotherapy with cisplatin and 5-fluorouracil is routinely used to treat patients with OSCC, and the combined use of gefitinib with cytotoxic drugs has been reported to enhance the sensitivity of cancer cells in vitro . However, the development of drug resistance because of prolonged chemotherapy is inevitable, leading to a poor prognosis. Therefore, understanding alterations in signaling pathways and gene expression is crucial for overcoming the development of drug resistance. However, the altered characterization of Ca2+ signaling in drug-resistant OSCC cells remains unclear. In this study, we investigated alterations in intracellular Ca2+ ([Ca2+]i) mobilization upon the development of gefitinib resistance in human tongue squamous carcinoma cell line (HSC)-3 and HSC-4 using ratiometric analysis. This study demonstrated the presence of altered epidermal growth factor- and purinergic agonist-mediated [Ca2+]i mobilization in gefitinib-resistant OSCC cells. Moreover, Ca2+ content in the endoplasmic reticulum, store-operated calcium entry, and lysosomal Ca2+ release through the transient receptor potential mucolipin 1, were confirmed to be significantly reduced upon the development of apoptosis resistance. Consistent with [Ca2+]i mobilization, we identified modified expression levels of Ca2+ signaling-related genes in gefitinib-resistant cells. Taken together, we propose that the regulation of [Ca2+]i mobilization and related gene expression can be a new strategy to overcome drug resistance in patients with cancer.

Maritime monitoring requirements have been beyond human operators capabilities due to the broadness of the coverage area and the variety of monitoring activities, e.g. illegal migration, or security threats by foreign warships. Abnormal vessel movement can be defined as an unreasonable movement deviation from the usual trajectory, speed, or other traffic parameters. Detection of the abnormal vessel movement requires the operators not only to pay short-term attention but also to have long-term trajectory trace ability. Recent advances in deep learning have shown the potential of deep learning techniques to discover hidden and more complex relations that often lie in low dimensional latent spaces. In this paper, we propose a deep autoencoder-based clustering model for automatic detection of vessel movement anomaly to assist monitoring operators to take actions on the vessel for more investigation. We first generate gridded trajectory images by mapping the raw vessel trajectories into two dimensional matrix. Based on the gridded image input, we test the proposed model along with the other deep autoencoder-based models for the abnormal trajectory data generated through rotation and speed variation from normal trajectories. We show that the proposed model improves detection accuracy for the generated abnormal trajectories compared to the other models.

Nypa fruticans Wurmb (NFW) contains a large amount of phenolic acid and flavonoids, and is popular as a superfood in Myanmar. NFW has various biological activities, such as anti-inflammatory, anti-oxidant, and neuroprotective properties; however, the anti-cancer effect of NFW have not been reported. In this study, we investigated the anticancer activity of water extracts of NFW (WeNFW) and the underlying mechanism in human FaDu hypopharyngeal squamous carcinoma cells. The WeNFW inhibited FaDu cell growth in a dose-dependent manner without affecting normal cells (L929), as determined by an MTT assay and Live and Dead assay. In addition, the concentrations of WeNFW without cytotoxicity (0.025, 0.05, and 0.1 mg/mL) inhibited wound healing and colony formation. Furthermore, WeNFW significantly induced apoptosis through the proteolytic cleavage of caspase-3 and -9, poly (ADP-ribose) polymerase, and downregulation of Bcl-2 and upregulation of Bax in FaDu cells, as determined by DAPI staining, FACS analysis, and western blot analysis. Taken together, these results suggest that WeNFW exhibits potent anti-cancer effects by suppressing the growth of oral cancer cells, wound healing and colony formation activity. Via mitrochondrial-dependent apoptotic pathways in human FaDu hypopharyngeal squamous carcinoma cells. Therefore, WeNFW can provide a natural chemotherapeutic drug for oral cancer in humans.

COVID-19 has been spreading all around the world, and threatening global health. In this situation, identifying and isolating infected individuals rapidly has been one of the most important measures to contain the epidemic. However, the standard diagnosis procedure with RT-PCR (Reverse Transcriptase Polymerase Chain Reaction) is costly and time-consuming. For this reason, pooled testing for COVID-19 has been proposed from the early stage of the COVID-19 pandemic to reduce the cost and time of identifying the COVID-19 infection. For pooled testing, how many samples are tested in group is the most significant factor to the performance of the test system. When the arrivals of test requirements and the test time are stochastic, batch-service queueing models have been utilized for the analysis of pooled-testing systems. However, most of them do not consider the false-negative test results of pooled testing in their performance analysis. For the COVID-19 RT-PCR test, there is a small but certain possibility of false-negative test results, and the group-test size affects not only the time and cost of pooled testing, but also the false-negative rate of pooled testing, which is a significant concern to public health authorities. In this study, we analyze the performance of COVID-19 pooled-testing systems with false-negative test results. To do this, we first formulate the COVID-19 pooled-testing systems with false negatives as a batch-service queuing model, and then obtain the performance measures such as the expected number of test requirements in the system, the expected number of RP-PCR tests for a test sample, the false-negative group-test rate, and the total cost per unit time, using the queueing analysis. We also present a numerical example to demonstrate the applicability of our analysis, and draw a couple of implications for COVID-19 pooled testing.

본 논문은 종교적 언어가 신을 나타낼 수 있음을 보여주고자 한다. 종교적 체험과 종교적 언어의 관계성에서, 중요한 주제들 중의 하나는 신적 체험을 전달 하는데 사용되는 언어가 인간의 조건과 존재론적으로 명확히 구별되는 신을 나타낼 수 있는가의 문제를 다루는 것이다. 신과 세계의 사이에는 차이 혹은 간격이 있다. 왜냐하면 초월적 존재로서 신은 인간이 이해할 수 없는 존재의 측면을 가지고 있기 때문이다. 신에 대한 이해불가능성은 아마도 인간 언어가 지니고 있는 한계점들을 암시하고 있을 것이다. 즉 인간 언어는 인간이 이해할 수 없는 것을 표현할 수 없는 한계점이 있다. 그러나 세계가 신을 나타낼 수 있는 중요 한 영역들 중의 하나는 바로 경험의 세계이다. 한 개인은 바로 경험의 역동성을 통해서 신을 만나게 된다. 신에 대한 인간의 체험을 전달하는 것은 바로 인간의 언어이다. 그리고 이러한 인간의 언어는 현존하는 것뿐만 아니라 부재하는 것도 드러낼 수 있다. 따라서 본 논문은 어떻게 종교적 언어가 신을 나타낼 수 있는 가에 대해서 보여주고자 한다. 전통과 공동체의 중요성, 종교적 언어의 본질, 그리고 종교적 언어의 변화적 힘 등이 논의될 것이다.

The 17th APEC Future Education Forum (AFEF) and the 19th International ALCoB Conference were held from 28 September (Tuesday) to 1 October (Friday) in a virtual manner. The annual forum and conference serve as an invaluable opportunity to discuss future directions of education and human resources development in the Asia-Pacific region. Since 2005, the forum and conference have served their role as the largest and longest thematic meeting in the APEC Human Resources Development Working Group (HRDWG). The 2021 forum and conference have gathered 780 participants from 20 APEC member economies, guest economies and international institutions. Under the theme “Strengthening lifelong competencies and skills development for individuals’ career, education, training, and life cycles”, the forum and conference reflected the current educational agenda from 21 APEC member economies and other international organizations such as G20, UNESCO. As a way forward, the forum and conference speakers recommend APEC to 1) consider individual and industrial needs for curriculum development, 2) expand lifelong learning policies and practices at both domestic and international level and 3) develop a public-private partnership to prepare its future talents with adequate competencies. This review explains the 17th AFEF and the 19th International ALCoB Conference background, summary and outcomes. The review also briefs on collective actions member economies can take as future steps to continue the forum and conference discussions.

This article suggests the machine learning model, i.e., classifier, for predicting the production quality of free-machining 303-series stainless steel(STS303) small rolling wire rods according to the operating condition of the manufacturing process. For the development of the classifier, manufacturing data for 37 operating variables were collected from the manufacturing execution system(MES) of Company S, and the 12 types of derived variables were generated based on literature review and interviews with field experts. This research was performed with data preprocessing, exploratory data analysis, feature selection, machine learning modeling, and the evaluation of alternative models. In the preprocessing stage, missing values and outliers are removed, and oversampling using SMOTE(Synthetic oversampling technique) to resolve data imbalance. Features are selected by variable importance of LASSO(Least absolute shrinkage and selection operator) regression, extreme gradient boosting(XGBoost), and random forest models. Finally, logistic regression, support vector machine(SVM), random forest, and XGBoost are developed as a classifier to predict the adequate or defective products with new operating conditions. The optimal hyper-parameters for each model are investigated by the grid search and random search methods based on k-fold cross-validation. As a result of the experiment, XGBoost showed relatively high predictive performance compared to other models with an accuracy of 0.9929, specificity of 0.9372, F1-score of 0.9963, and logarithmic loss of 0.0209. The classifier developed in this study is expected to improve productivity by enabling effective management of the manufacturing process for the STS303 small rolling wire rods.

Recently, the importance of preventive maintenance has been emerging since failures in a complex system are automatically detected due to the development of artificial intelligence techniques and sensor technology. Therefore, prognostic and health management (PHM) is being actively studied, and prediction of the remaining useful life (RUL) of the system is being one of the most important tasks. A lot of researches has been conducted to predict the RUL. Deep learning models have been developed to improve prediction performance, but studies on identifying the importance of features are not carried out. It is very meaningful to extract and interpret features that affect failures while improving the predictive accuracy of RUL is important. In this paper, a total of six popular deep learning models were employed to predict the RUL, and identified important variables for each model through SHAP (Shapley Additive explanations) that one of the explainable artificial intelligence (XAI). Moreover, the fluctuations and trends of prediction performance according to the number of variables were identified. This paper can suggest the possibility of explainability of various deep learning models, and the application of XAI can be demonstrated. Also, through this proposed method, it is expected that the possibility of utilizing SHAP as a feature selection method.

The study investigated the individual coaching effect on TOEIC learning among college students. The participants were the 145 college students in Incheon who had taken TOEIC reading comprehension classes for two semesters. Two series of simple TOEIC tests were executed to measure the students’ English proficiency on the first day of each semester. Individual coaching was conducted through counseling and learning guidance for 25 students with the lower scores (3~7 points out of 25 based on the first simple TOEIC test). Among them, eight students participated in the in-depth interview at the beginning of each semester. When comparing the simple TOEIC test results of the two groups, the difference between the averages of the two groups was clear only with regard to the first semester. The t-test showed no proven statistical differences in the second semester outcomes. The results of paired-sample t-test on the change in the simple TOEIC scores before and after individual coaching in the individual and class coaching mixed group was also statistically verified. Individual coaching in this study was to find an appropriate learning process for the students with low language fluency, and it took place for a relatively long time. The interaction between the students and the professor in individual coaching created a special rapport between them.

고치벌과에 속하는 Microgastrinae 아과의 Diolcogaster perniciosa (넓적다리도랑꼬마고치벌)을 한국에서 처음으로 보고한다. 본 종의 재기 재, 진단, 분포정보, 그리고 삽화를 제공한다.

Laser cladding a surface treatment process that grants superior characteristics such as toughness, hardness, and corrosion resistance to the surface, and rebuilds cracked molds; as such, it can be a strong tool to prolong service life of mold steel. Furthermore, compared with the other similar coating processes – thermal spray, etc., laser cladding provides superior bonding strength and precision coating on a local area. In this study, surface characteristics are studied after laser cladding of low carbon steel using 18%Cr-2.5%Ni-Fe powder (Rockit404), known for its high hardness and excellent corrosion resistance. A diode laser with wavelength of 900-1070 nm is adopted as laser source under argon atmosphere; electrical power for the laser cladding process is 5, 6, and 10 kW. Fundamental surface characteristics such as crossectional microstructure and hardness profile are observed and measured, and special evaluation, such as a soldering test with molten ALDC12 alloy, is conducted to investigate the corrosion resistance characteristics. As a result of the die-soldering test by immersion of low carbon alloy steel in ALDC12 molten metal, the clad layer's soldering thickness decreases.

Background: Physical activity and quality of life (QOL) influence the health status of older adults. Recently, the use of wearable devices to monitor physical activity has increased. Objects: This study examined the relationship between the amount of physical activity, measured using a wearable device, and QOL among older adults. Methods: In total, 71 older adults (aged ≥ 65 years) were enrolled. The amount of physical activity was measured using a wearable device with a wrist strap, and daily physical activity was classified according to intensity (sedentary, light, moderate, or very active). Self-reported QOL was evaluated using the Short Form 36 (SF-36) questionnaire. Pearson and Spearman correlation analyses were conducted to analyze parametric and non-parametric variables, respectively. The relationship between amount of daily physical activity and SF-36 scores was assessed. Results: The correlation analyses revealed positive correlations between the amount of moderate- intensity and very active physical activity (minutes/day) and SF-36 scores (p < 0.05). Conclusion: Physical activity of at least moderate intensity is associated with better QOL in older adults. Further studies are required to verify the effects of increased physical activity on QOL in older adults.

Since the Japanese government recently unveiled a plan to release radioactive water into the ocean, the neighbouring countries have expressed concerns. In particular, certain environmental groups claimed that the execution of this operation would have a significant impact on the marine environment in the region. In light of significant potential risks, this article argues that such an operation is likely to trigger an international dispute at an international court or tribunal for several reasons. Accordingly, this article would like to explore the highly likely international litigation. First, the background of this potential international litigation, including the reasons why the operation may end up at an international court or tribunal are addressed. Subsequently, certain legal and factual issues that are expected to be contested between the parties at the court or tribunal are discussed. Finally, this article discusses some of the expected outcomes of this likely international litigation, including reparation.