Food toxins are regarded as a major source of health risks, serious illnesses susceptible to even death. These dangerous pathogens may lead to significant economic impact worldwide. The food production chain undergoes different stages like harvesting, processing, storage, packaging, distribution, and lastly preparation, and consumption. Therefore, each step is susceptible to risks of environmental contamination. Nowadays, the carbon quantum dots (CDs) are regarded as one of the most widely used hybrid carbon nanomaterials due to their different magical physical and chemical properties. The CDs have a size below 10 nm and show the fluorescent property. The CDs find vast applications in different fields like sensing, food safety, drug delivery, bioimaging, catalyst, energy conversion, etc. Compared to other available methods, the fluorescence detection techniques have low cost, easy handling, and safe operating system. There is a need for a review to compile the fluorescence properties of carbon nanodots used to detect food pathogens. This brief review is addressed in that direction and mostly focused on the synthesis of carbon dots-based fluorescence sensors for detecting pathogens and toxins in foods and beverages. The detailed mechanisms and origin of fluorescence properties of carbon quantum dots are also highlighted herewith.
In order to manufacture a mask to prepare for infectious diseases such as COVID-19 and yellow dust, it is manufactured through the process of input, fusion, cutting, band attachment, defect inspection, and packaging. Domestic mask producers introduced Chinese facilities to keep up with explosive demand due to the rapid spread of COVID-19 in 2020, but serious problems arise in durability. Therefore, domestic processing and tooling companies have developed and supplied molds, but since supply is not smooth compared to demand, research on the development of mask molds with durability reliability is urgently needed to supply masks stably. This technology development aims to supply a mask with excellent quality to a market by applying dots capable of welding and re-painting to a mold for cutting applied to a mask manufacturing process and developing dots optimized for paper angles.
In this study, we intend to develop a control valve with oxidation resistance for hydrogen fluoride that can be applied to the semiconductor production process. Operated Valves currently in use is a form of assembling an air cylinder to the valve body. These valves generally have a cylinder body made of aluminum (Al), so they may corrode depending on the external environment, and the solution leaks along the rod inside the cylinder, causing damage to parts due to corrosion. To solve this problem, the valve plug shape was developed by devising and applying a plug using a valve different from the existing method, and it is possible to block the inflow of hydrogen fluoride into the valve control unit, thereby preventing damage to parts as well as maintaining stable valve operation.
In this study, to develop and verify the Jeju-type groundwater thermal system design program, the energy consumption and system performance derived by input into the design program based on the load calculated on the demonstration site and the groundwater temperature were compared and analyzed with the actual measured values. The theoretical values of energy consumption and heating and cooling COP obtained through the Jeju-type groundwater thermal system design program were 11.24kW, 5.28 for heating, 13.31kW, 3.94 for cooling respectively. The measured values of energy consumption and COP of the Jeju-type groundwater thermal system were 3967.2kW and 4.5, respectively. The error between the theoretical value and the measured value obtained through the design program is 0% and 2.39%, respectively. The errors that occur in the predicted values and the actual values are due to variables that are ignored in the system assumptions. If users consider errors and use it when designing groundwater thermal systems, they can estimate the cost of required drilling works, heat exchangers, and heat pumps and analyze economic feasibility.
The prediction of algal bloom is an important field of study in algal bloom management, and chlorophyll-a concentration(Chl-a) is commonly used to represent the status of algal bloom. In, recent years advanced machine learning algorithms are increasingly used for the prediction of algal bloom. In this study, XGBoost(XGB), an ensemble machine learning algorithm, was used to develop a model to predict Chl-a in a reservoir. The daily observation of water quality data and climate data was used for the training and testing of the model. In the first step of the study, the input variables were clustered into two groups(low and high value groups) based on the observed value of water temperature(TEMP), total organic carbon concentration(TOC), total nitrogen concentration(TN) and total phosphorus concentration(TP). For each of the four water quality items, two XGB models were developed using only the data in each clustered group(Model 1). The results were compared to the prediction of an XGB model developed by using the entire data before clustering(Model 2). The model performance was evaluated using three indices including root mean squared error-observation standard deviation ratio(RSR). The model performance was improved using Model 1 for TEMP, TN, TP as the RSR of each model was 0.503, 0.477 and 0.493, respectively, while the RSR of Model 2 was 0.521. On the other hand, Model 2 shows better performance than Model 1 for TOC, where the RSR was 0.532. Explainable artificial intelligence(XAI) is an ongoing field of research in machine learning study. Shapley value analysis, a novel XAI algorithm, was also used for the quantitative interpretation of the XGB model performance developed in this study.
본 논문에서는 BIM을 활용한 흙막이 시스템을 개발하고 소개한다. 선행 연구 분석을 통해서 흙막이 BIM 시스템을 이루는 기술들 에 대한 조사를 바탕으로 요소 기술들을 개발하였다. 첫 번째 요소 기술로, 선행 연구 및 표준 등을 활용해 BIM라이브러리를 구축하여 범용성과 재사용성을 확보하였다. 두 번째로, 토공 2D 기반의 토공 물량 산출법들을 분석하고 흙막이 BIM 시스템으로 활용하되 추가 로 IDW 보간법을 활용하여 지형 생성 및 토공량 산출 시스템을 구축하였다. 세 번째로, 물량 산출을 위한 4가지 수식을 제안하여 객체 마다 각각 다르게 물량 산출법을 적용하여 개발하였다. 이후, 시스템에서 산출되는 물량산출서와 2D 기반 물량산출서와의 비교와 검 증을 통해서 시스템이 앞으로 나아가야할 방향과 한계에 대해 알아보았다.
본 연구에서는 비닐멀칭된 외두둑에서의 배추 수확을 위한 시작기(A, B-1, B-2)를 설계 및 제작하였고, 시험을 통해 배추 수확을 위한 인발 장치부, 절단 장치부, 이송 장치부 등의 작업공정별 성능과 전체 작업성능을 분석하였다. 이론 분석을 통해 작업속도 0.2 m/s, 이송 벨트 각도 20∼35°, 이론적 이송 벨트의 적정 이송 속도를 작업속도보다 1.5배 빠르게 설정하여 청풍 및 춘광 품종을 대상으로 현장시험을 실시하였다. A형 시험 결과, 인발⋅이송성능은 성공률이 50% 수준으로 낮았으며, 절단성능의 경우 배추의 상품성이 양호한 경우가 35%, 과절단된 경우가 10% 및 미절단된 경우가 55%로 전반적으로 배추의 절단상태가 불량하였다. B형 시험 결과, 스핀들 인발장치는 비닐멀칭된 두둑에서는 감김현상으로 작업이 불가하였으며, 비닐멀칭없는 두둑에서의 인발⋅이송성능은 성공률이 78% 수준으로 A형보다 높아졌으나, 절단성능의 경우 배추의 상품성이 양호한 경우가 7.7%, 과절단된 경우가 15.4% 및 미절단된 경우가 76.9% 로 오히려 배추 절단상태는 더욱 불량해진 것으로 나타났다. 본 시작기의 비닐멀칭된 두둑에서의 현장시험 결과, 배추 인발, 절단 및 이송성능이 불량하게 나타나 인발, 절단, 이송작업에서의 전반적인 구조개선이 필요한 것으로 판단되었다.
이 연구의 목적은 공공기관이 스마트시티 사업을 수행함에 있어 어느 정도의 수준과 역량을 보유하고 있는지 판단하기 위한 수준진단 프레임워크를 수립하는 것이다. 이러한 연구목적 달성을 위해 기존의 지자체 GIS수준평가 방법과 국토부의 스마트시 티 인증체계 기준, 미래사회의 변화 모습 등 다양한 요소를 검토하여 최종적으로는 스마트시티 인프라역량, 기술 및 데이터 보유역 량, 연계통합역량, 미래의 스마트시티 정책수용역량 등 4개의 분야의 총 50개 세부 항목을 도출하고, 이를 계량화시킬 수 있는 틀을 마련하였다. 이 프레임워크를 공공기관 A, B, C에 적용한 결과를 상호비교하였다. 본 연구에서 제시한 스마트시티 사업수행 수준진단 틀은 각 기관에서 시간이 흐른 후에 역량 변화에 활용될 수도 있고, 각 기관의 특성에 맞게 일부 세부항목을 변경하여 활용될 수 있을 것이며, 각 기관이 스마트시티 분야의 활동계획과 전략을 수립하기 위해, SWOT 분석 대신 활용할 수 있을 것이다
Since the beginning of the second Sino-Japanese war in 1937, the entire Korean Peninsula has entered a full-fledged wartime system. Japan enacted laws that strongly regulate the distribution of various resources for war, and the same was implemented in Joseon. In particular, as iron, copper, lead, tin, and aluminum were mobilized as raw materials for military supplies such as weapons, private distribution decreased significantly, which had a great impact on the construction industry. As the use of metal such as steel as building materials requires permission from the provincial governor, it has become difficult to supply and demand except for some military facilities. In addition, the Japanese Ministry of Commerce and Industry encouraged research and development and manufacturing to promote the so-called “substitute goods industry” to make up for the shortage of supplies. Products with improved performance through chemical treatment by injecting only a small amount of the same raw material than before or using alternative raw materials have been developed. It was intended to overcome the limitations of lack of raw materials through the chemical industry. In terms of building materials, various substitutes were produced due to the incorporation of petrochemicals and the use of synthetic resins. This trend continued even after the end of the war and served as one of the backgrounds for R&D and production of new materials without returning to the “substitute goods.”
The TMD has a simpler structure than other vibration control devices and shows excellent control performance for the standardized vibration occurring in the structure. However, when the vibration cycle of the structure coincides with the vibration cycle of the TMD due to the sudden external loads, the off-tuning occurs, which threatens the structure while increasing the vibration width of the TMD. Therefore, Electromagnetic Tuned Mass Damper (ETMD) was developed as a semi-active TMD that prevents off-tuning while exhibiting excellent control performance like TMD. To verify the control performance of the developed ETMD, the bending behavior control performance evaluation experiment using a simple beam bridge was performed. The experimental method compared the mutual control power by experimenting with the existing TMD method and the developed ETMD under nine excitation frequency conditions. As a result, it was confirmed that the control effect of ETMD was about 4.85% higher than that of TMD at 3.02Hz, which generates the maximum displacement in the simple beam bridge. Also, the off-tuning occurred in some excitation conditions when using TMD, although the off-tuning did not occur when using ETMD. Therefore, the excellent control performance of the ETMD developed in this study was verified.
Magneto-Rheological Fluid (MRF) is a functional fluid in which flow characteristics change into magnetic force due to its magnetic particles. When the semi-active control device does not use MRF for a long time, precipitation of magnetic particles and abnormal control force occur. Thus, Electro Magneto-Rheological Fluid (EMRF), which improves the precipitation of magnetic particles for MRF and exhibits existing control performance, was developed in this study. First, the optimal mix proportion ratio was selected by conducting a precipitation experiment and a controlled force test by varying the content of grease based on the existing MRF components. Also, EMRF was applied to the shear-type damper to evaluate the control performance when applied to the control device. The cylinder-type damper was developed to apply to the structure, and control performance evaluation was conducted. The result confirmed that the precipitation of the magnetic particles was improved, while the damper using EMRF exhibited excellent control performance.
A thermally conductive film can be used to laterally conduct heat along the surface of glass windows, toward its edges where a heat sink could be located, thereby reducing temperature differential between the inside and outside surfaces of the window and thus lowering cross-sectional conductive heat transfer. This technique can offer optimized thermal energy management to modern buildings without the weight and cost of double- or triple-glazed window panels. In this work, a thermally conductive film was developed using carbon dots with inherently high thermal conductivity. Nitrogen atoms were then added to the carbon dots structure to intensify high-frequency phonon that would result in higher lateral thermal conductivity. The nitrogen-decorated carbon dots (NCDs) were prepared by a simple hydrothermal synthesis of citric acid with the addition of ethylenediamine as the N source. The NCDs were added to a cellulose-based solution and drop-casted onto FTO glass resulting in a transparent, laterally thermally conductive film, that also blocks ultraviolet (UV) and high-intensity blue light radiation. The visible-light transmission of the NCDs’ film was found to be up to 65%, comparable to the commercial solar films. The lateral thermal conductivity of the NCDs’ film increases with increasing N content up to an optimum level, suggesting the role of N to “concentrate’ the high-frequency phonons responsible for effective lateral thermal conductivity of the films.
Flipped learning research has been applied in various educational fields since 2015 and the educational effects have been discussed in previous literature. In the beauty field, flipped learning research is insufficient; in particular, it is difficult to find research on flipped learning specifically concerning nail beauty education. The purpose of this study is to develop a model for applying flipped learning to nail beauty education which should involve practical training based on theory. Such an approach is considered effective. Data were collected and analyzed focusing on previous studies with flipped learning applied as a research method. The subject of the research is “Nail Color Design 1”, a common nail major elective subject at J college. The “Nail Color Design 1” course is a practice-oriented course in the form of theory and practical classes. Consequently, the flipped learning education model for nail beauty was designed by reflecting learners’ needs through the ADDIE instructional design model. It was applied based on the education structure of the Pre-class, In-class, and Post-class of the PARTNER instructional learning model. This study deviates from the traditional practical education model, and has educational significance as a practical model in which flipped learning is applied to nail beauty subjects and self-reflection is derived through project practice.
다양한 동물 모델이 인간 질병, 의약품의 효능 및 작용 메커니즘을 연구하는 데 사용되고 있다. Zebrafish(Danio rerio)는 여러 가지 장점이 있어 인간 질병에 대한 중개 연구의 모델로 점점 더 폭넓게 활용되고 있다. 본 논문은 Pubmed, Google Scholar, Scopus에서 2020년 12월까지 최근 10년간 zebrafish 모델, 천연물(한약), in vivo 스크리닝의 키워드를 사용하여 저널에 게재된 논문을 검토하여 필 요한 정보를 얻었다. 이 리뷰에서 우리는 천연물(한약) 연구에 대한 다양한 제브라피쉬 질병 모델의 최 근 경향에 대해 논의하였다. 특히, 암, 안질환, 혈관 질환, 당뇨병 및 합병증, 피부질환에 중점을 두었고, zebrafish 배아를 사용하여 이들 질병에 대한 의약품의 분자 작용 메커니즘에 관해 언급하였다. Zebrafish는 실험실에서 임상 연구까지의 격차를 줄이는 데 중추적 역할을 할 수 있는 중요한 동물 모 델이다. Zebrafish는 의약품이나 화장품 개발, 질병의 병인론을 이해하기 위해 사용되고, 이로 인해 생의 학 연구에서 설치류의 사용을 줄이는 데 크게 기여하고 있다.
The goal of this study was to develop a curriculum based on practice and job competency, reflecting opinions on the required job competence of nail practitioners and professionals related to nail beauty. Through in-depth interviews with nail experts, the research focuses on developing nail beauty competency-based curriculum and curriculum profiles that reflect practitioners’ needs of job competence in the field. In-depth interviews with 11 field experts and surveys of 154 people were conducted to develop a competency-based curriculum for beginner nail hairdressers. The results of this study show that the existing 38 National Competency Standards (NCS) job competencies were reduced to 21 job competencies. In addition, based on the common opinions of experts who reflect the current trend, two tasks on “eyelashes” and “waxing” were added, and they were modified and supplemented with 23 core competencies. The development of a competency-based curriculum and educational programs for nail beauty was performed based on the requirements of the core competencies investigated and the development of a systematic map for the core competencies of beginner nail technicians and hairdressers. In conclusion, the need for professional education and training for nail hairdressers is growing, and it can be seen that a curriculum building multi-faceted abilities is needed for their qualifications as experts. This study found that it is necessary to develop interpersonal communication skills that include marketing elements other than practical skills such as personality and customer response methods in the nail beauty curriculum.
This study aims to develop the designs and patterns of yoga tops that are better adjusted to suit females in their 30s and 40s. After conducting a comparative analysis of three different popular yoga garments, one yoga top currently on the market was selected. Subsequently, a fit evaluation was conducted on Trail 1-garment α, which was developed body analysis performed based on selected yoga top C, followed by the production of the Trial 2 garment after making adjustments according to the comparative observation results. Based on these results, garment C with the longest top length was evaluated as the best. The results of the evaluation of appearance and fit conducted of Trial 1-garment α compared to those of C showed that Trial 1-garment α was superior in both evaluations. Trial 2-garment β was produced after making improvements on Trial 1-garment α and then placed under identical comparative evaluation condition as Trial 1-garment α. Results showed a significant improvement compared to Trial 1-garment α, and the Trial 2 garment with an additional arm pattern was shown to be superior in shoulder strap width stability, shoulder strap pressure, chest stability, degree of waist pressure, waist comfort, general fitting, and supportiveness.
The purpose of this study is to develop Korean clothing designs that can satisfy future consumer’s needs based on the elements extracted through the content analysis method in a study on the design elements expressed in traditional outfits in the 2010s. To this end, data analyzing Hanbok in wedding magazines were used, and after extracting design elements, research methods for empirical design development were used. After subclassifying the major design elements, factors with a steady increase in frequency and appearance rate were identified. Through this, five elements capable of aesthetic sampling were extracted by complex expression methods and expressed in a total of seven combinations. The types extracted from the design elements are items, silhouette, top shape, skirt shape, skirt length, mixed items with increasing frequency. In the element of color, the adjacent color harmony, which showed the highest frequency of color, and the white-blue harmony, which showed an increase among them, were extracted. When using materials, top and skirt have similar usage rates of the same and different materials, so both contents were extracted, and many patterns were arranged in the top and the whole, but these three were extracted because there were increasing cases where there were no patterns. In the case of decoration, embroidery, pintuck, sakdong, applique, lace, ribbon on the top, silver foil and print on the skirt were extracted. Through this study, it was possible to propose a future Korean costume design model.
On October 22, 2021, the Ministry of Commerce of the People’s Republic of China (PRC) promulgated the Development Plan for the Utilization of Foreign Capital during the 14th Five-Year Period. The plan has attracted wide attention from investors and scholars at home and abroad. The global economic recovery is full of unpredictable challenges due to the spread of Covid-19, so absorbing foreign investment is critical to the economic development in most countries. The plan was based on the 14th Five-Year Plan for National Economic and Social Development and the Outline of Long-term Objectives for 2035. China is changing the direction of attracting investment from manufacturing industry to service industry. This article discusses China’s current utilization of foreign capital and analyzes the newly promulgated plan, including its key features, overall objectives, and basic tasks. It also examines the opportunities and challenges China faces in its future utilization of foreign capital.
This paper aims to examine the progressive development process of the ASEAN under the UN 2030 Agenda for sustainable development. As of 2022, the ASEAN Member States have a total population of 622 million people and a combined GDP of USD 3.2 trillion. The ASEAN’s main focus is integration by connectivity which has been facilitated by “the ASEAN Way.” The ASEAN connectivity was upgraded into a single community through the ASEAN Vision 2020 comprehensively formalized by the Bali Concord II in 2003. The ASEAN has been geographically expanding towards Northeast Asia (ASEN+3) and then Oceania with India (ASEAN+6). It was also connected to the Regional Comprehensive Economic Partnership (RCEP) which is the biggest mega FTA in the contemporary world. With the Vision 2025, furthermore, the ASEAN Community reset its direction to sustainable development goals which are the main objective to attain for the Association under the Master Plan 2025.
Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1) is an N6-methyladenosine (m6A) RNA modification regulator and a key determinant of premRNA processing, mRNA metabolism and transportation in cells. Currently, m6A reader proteins such as hnRNPA2/B1 and YTHDF2 has functional roles in mice embryo. However, the role of hnRNPA2/B1 in porcine embryogenic development are unclear. Here, we investigated the developmental competence and mRNA expression levels in porcine parthenogenetic embryos after hnRNPA2/B1 knock-down. HhnRNPA2/B1 was localized in the nucleus during subsequent embryonic development since zygote stage. After hnRNPA2/B1 knock-down using double stranded RNA injection, blastocyst formation rate decreased than that in the control group. Moreover, hnRNPA2/B1 knock-down embryos show developmental delay after compaction. In blastocyste stage, total cell number was decreased. Interestingly, gene expression patterns revealed that transcription of Pou5f1, Sox2, TRFP2C, Cdx2 and PARD6B decreased without changing the junction protein, ZO1, OCLN, and CDH1. Thus, hnRNPA2/B1 is necessary for porcine early embryo development by regulating gene expression through epigenetic RNA modification.