6-Gingerol exerts anti-tumor effects in various cancer cell models. We evaluated the effect of 6-gingerol on the growth of MCF-7 breast cancer cells and MCF-10A breast epithelial cells to determine whether any growth-inhibitory effects found were attributable to apoptosis, and to elucidate the underlying mechanism of action. 6-Gingerol inhibited the viability of both cell lines in a dose- and time-dependent manner; however, the degree of inhibition was greater in MCF-7 than MCF-10A cells. By flow cytometry, induction of dose- and time-dependent apoptosis was found, and the magnitude of apoptosis was also markedly greater in MCF-7 than MCF-10A cells. Expression of caspase-3 and poly (ADP-ribose) polymerase (PARP) was observed in MCF-7 cells treated with 6-gingerol, and further cleavage of PARP occurred in these cells. We suggest that 6-gingerol induces apoptosis in human breast cancer cells mainly by promoting caspase-3 expression and subsequent degradation of PARP.

We identified research trends for freshwater exotic species in South Korea using text mining methods in conjunction with bibliometric analysis. We searched scientific and common names of freshwater exotic species as searching keywords including 1 mammal species, 3 amphibian-reptile species, 11 fish species, 2 aquatic plant species. A total of 245 articles including research articles and abstracts of conference proceedings published by 56 academic societies and institutes were collected from scientific article databases. The search keywords used were the common names for the exotic species. The 20th century (1900’s) saw the number of articles increase; however, during the early 21st century (2000’s) the number of published articles decreased slowly. The number of articles focusing on physiological and embryological research was significantly greater than taxonomic and ecological studies. Rainbow trout and Nile tilapia were the main research topic, specifically physiological and embryological research associated with the aquaculture of these species. Ecological studies were only conducted on the distribution and effect of large-mouth bass and nutria. The ecological risk associated with freshwater exotic species has been expressed yet the scientific information might be insufficient to remove doubt about ecological issues as expressed by interested by individuals and policy makers due to bias in research topics with respect to freshwater exotic species. The research topics of freshwater exotic species would have to diversify to effectively manage freshwater exotic species.

The Plant Extract Bank was established by 21 Century Frontier R&D Program. It has began selling a research plant extract samples to support many Korean scientists since 2001. The plant extracts were tested for insecticidal activities. A total of 19,100 ethanolic and methanolic extracts of differentplant species from 23 nations including Costa Rica, Philippines, India and South Africa were evaluated for their larvicidal activities against Aedes aegypti, the major vector of dangue, dangue hemorhagic fever and yellow fever. The larval mortalities were observed 24h after treating the larvae to the extracts. At 500 ppm, 754 extracts showed >80% larval mortality in the 24h exposure. Among the extracts tested, the highest larval mortality was observed in the methanol extracts of Piper guianense, P. nigrum, P. mocropodum, P. sem-immersum, P. magen and P. pubicatulm.

This study examined relationships among healthy food awareness, behavioral intention toward healthy foods, and actual behavior of Generation Y consumers. This study hypothesized that Generation Y consumers are aware of healthy foods and more likely to eat healthy foods while avoiding junk foods. According to structural equation modeling, all hypothesized paths were statistically significant, meaning that the three constructs in the model showed positive relationships with each other. Results showed that this group of college students is generally aware of healthy foods and have positive intentions toward healthy food choices. Therefore, university foodservice management needs to continue to improve their menus in order to attract this new generation of college student consumers.

Prostate cancer is a leading cause of death among the aging men. Surgical or radio therapy is effective when the cancer is confined to the prostate gland but once the cancer spreads beyond the pelvis, even chemotherapy and hormonal ablation therapy fails in curing this disease. Our previous studies have shown that β-glucan induces apoptosis in prostate cancer cells. Cellular viability of these cells treated with β-glucan was measured by MTT assay. β-glucan induced dose- and time-dependent inhibition of cell viability in LNCaP cancer cells. In flow cytometry analysis, β-glucan induced dose- and timedependent apoptotic activities in LNCaP cancer cells. In addition, increased of expression caspase-3, caspase-9, Bax, and cytochrome C but decreased of expression Bcl-2 was observed in LNCaP cells treated with β-glucan. These results suggest that β-glucan induces apoptosis in LNCaP human prostate cancer cells mediated mainly through the increased of expression caspase-3, -9, Bax, cytochrome C and decreased of expression Bcl-2.

주암호의 수질변동과 주요 생물 군집 특성을 조사하였다. 수질의 경우, 수온은 3.8~21.2􀆆C, 수소이온농도(pH)는 6.7~8.6, 전기전도도는 64~76 μs cm-1, 용존산소량(DO)은 5.3~13.2 mg L-1, 화학적산소요구량(COD)은 2.5~3.3mg L-1, 부유물질(SS)은 1.0~5.1 mg L-1, 총질소(TN)는 0.622~0.841 mg L-1, 총인(T-P)은 0.007~0.019 mg L-1, Chl-a 농도는 2.8~8.8 mg m-3로 나타났다. 수정 Carlson 지수(TSIm)에 따른 영양단계 평가 결과는 연평균 중영양 상태로 나타났다. 식물플랑크톤 총 출현종수는 53종으로 규조류 28종, 녹조류 13종, 남조류 3종, 기타 9종이 확인되었다. 현존량은 113~2,909 cells mL-1의 범위를 보였다. 동물플랑크톤 총 출현 종수는 16종으로 출현 분류군별로는 윤충류 10종, 지각류와 요각류가 각각 4종과 2종이 확인되었고 현존량은 309~435 ind. L-1의 범위로 나타났다. 저서성대형무척추동물은 총 12목 21과 33종으로 1038개체가 출현하였으며, 우점종은 등 줄하루살이였고 아우점종은 두점하루살이로 나타났다. 수생식물은 총 9종으로 정수식물 8종, 부유식물 1종이 확인되었다. 생태계교란야생식물로는 돼지풀과 물참새피가 출현하였다. 어류는 총 30종 613개체가 확인되었다. 한국 고유종은 10종으로 33.3%의 고유도를 나타냈고, 외래도입어종은 3종으로 침투도 10.0%로 나타났다.

This study demonstrates the investigation of zooplankton communities (e.g. rotifers, cladocerans and copepods) and environmentally related driving factors (e.g. elevation, area size, water depth, types of dike construction, and bottom substrates). We hypothesized that zooplankton community structure and composition would be influenced by ambient driving forces in different scales of the irrigation ponds (Dumbeong). A total of 66 zooplankton species/groups (56 rotifers, 9 cladocerans, 1 copepods) were found and identified at 45 Dumbeong of Goseong region (i.e. Goseong-gun) in 2011. The rotifers occupied 84.9% of the total zooplankton abundance. We could categorize a clear separation of zooplankton communities into 4 different patterns based on cluster analysis. Zooplankton diversities in Dumbeongs were lower than those in natural ponds or wetlands. In addition, community structure of zooplankton was also simpler and had a broken stick distribution based on SHE analysis. Species composition in each Dumbeong was not significantly discriminated each other. The result of canonical correspondence analysis (CCA) pinpointed that significant influential variables upon zooplankton community were dissolved oxygen percent saturation, pH, and Dumbeong’s material. This study indicated that morphological type of the Dumbeong and its water quality could determine the community structure of zooplankton. Furthermore, the connectivity between ambient habitats and materials could be necessary to be rigorously considered in respect to producing the Dumbeongs to subsidize alternative habitats for wetland ecosystem in freshwater landscape.

미소갑각류 군집과 이화학적 요인 간의 관계를 파악하 기 위해 우포늪에서 2001년부터 2010년 동안 2주 간격 으로 조사를 수행하였다. 조사 시간 동안, 총 10속의 지 각류가 동정되었으며, 서식 형태에 따라 구분된 부착성 지각류(Alona, Camptocercus, Simocephalus, Diaphanosoma, Sida)와 부유성 지각류(Bosmina, Ceriodaphnia, Daphnia, Moina, Scapholeberis)의 연 출현이 매우 상이한 것으로 나타났다. 부유성 지각류는 봄과 가을 시기에 높은 밀도로 나타났으며, 부착성 지각류는 여름 시기에 상대적으로 높은 밀도를 보였다. 요각류 성체와 유생 또 한 부착성 지각류와 유사한 계절적 분포 경향을 나타내 었다. 부유성 지각류는 강우량과 이화학적 요인과 상관성 을 보이지 않았으나, 부착성 지각류는 이화학적 요인 중 수온과 뚜렷한 상관성을 보였다(n=120, p⁄0.01). 특히 부착성 지각류 중 Chydoridae는 강우량 및 수온과 양의 상관관계를(n=120, p⁄0.01), 용존산소와 전기전도도와 는 음의 상관관계를 나타냈다(n=120, p⁄0.05). 요각류 군집은 강우량(n=120, p⁄0.01) 및 수온(n=120, p⁄0.05) 과 양의 상관관계를 나타내었다. 결론적으로 우포에서 강 우량은 미소갑각류 군집 분포를 결정하는 매우 중요한 요인인 것으로 파악되었다.

This study compares the abundance and community structure of zooplankton organisms from the littoral and pelagic regions, and considers particularly trophic levels vs. zooplankton abundances. Zooplankton samples, collected every 3 months over a year from 2010 to 2011 at 29 temperate lakes and reservoirs, which belong to two different river basins (Youngsan and Seomjin River). The spatial pattern of rotifers was similar to that of total zooplankton abundance. This reflected the fact that rotifers strongly dominated the zooplankton community. There were considerable spatial variations in total zooplankton abundance (ANOVA, p＜0.01), while there were no significant differences both in littoral and pelagic regions in abundance of zooplankton (ANOVA, p=0.205). The mean abundance of zooplankton in eutrophic systems was much higher than that of mesotrophic systems, while significant difference in number of species and diversity index were not shown in both trophic systems.

2011년 영산강∙섬진강 수계 29개 호소조사에서 동정된 식물플랑크톤은 규조강 161종, 녹조강 157종, 남조강 39종, 기타 67여종으로 총 424종이었다. 조사기간 동안 4차 조사시기에 상대적으로 더 다양한 종이 출현하였으며 대동호, 대동제, 소포제, 군곡제, 개초제, 둔전제 지점에서 다양한 종들이 출현하였고, 영산호를 비롯한 하천형 호소에서는 비교적 빈약한 종이 출현하였다. 각 지점에서 20% 이상의 우점율을 보인 종은 대부분 규조류였고 2차와 3차 조사에서 녹조류와 남조류도 우점의 빈도가 높아졌다. 개체군 밀도는 조사 호소나 시기에 따른 뚜렷한 패턴이 없었고 특정 종의 성장에 크게 의존하는 특성을 나타냈다. 클로로필-a의 농도는 조사호소와 시기에 따른 편차가 매우 컸으며 식물플랑크톤의 개체수와 일치하지 않는 것으로 나타났다. 총질소와 총인의 농도와 클로로필-a의 농도 사이에는 매우 낮은 상관성이 나타났다.

본 연구는 유기 벼 재배시 주로 이용되는 유기질비료가 토양화학성과 벼의 생장 및 수량에 미치는 영향을 구명하기 위해 수행되었다. 전남지역 벼 유기재배지에서 많이 이용되고 있는 유기질비료를 Organic fertilizer(이하 OF) I, 식물성 성분이 많이 함유된 비료(쌀겨 위주)를 OF II, 동물성 성분이 많이 함유된 비료를 OF III, 그리고 식물성과 동물성이 혼합된 비료를 OF IV로 나누어서, 벼 이앙 전에 전층시비로 토양에 골고루 처리하였다. 유기질비료내의 탄질율이 상대적으로 낮았던 OF I과 III이 OF II와 IV에 비교하여 시기별로 유기질비료의 질소 무기화가 빠르게 진행되었다. 토양의 시기별 유기물 함량은 유기질비료 투입량이 많았던 OF II와 IV에서 높게 나타났으며, 수확 후 토양의 화학성은 대체적으로 OF II와 IV에서 높게 나타났다. 벼 생장특성은 처리에 따른 차이는 나타나지 않았다.

The purpose of this study was to examine elderly drivers' driving performances at the intersections, suggested by Bao and Boyle(2009), according to visual information processing skills Visual information processing skills of elderly drivers were measured

낙동강 물금 지역에서 채집된 동물플랑크톤 중 윤충류인 Keratella 속을 대상으로 10년 전후(1995, 1997, 2005 그리고 2007)의 종조성 변화를 분석하고, 피갑형태에 다양한 변화를 보이는 K. cochlearis의 피갑 크기, 후돌기의 발현 여부 및 길이 그리고 후두돌기 길이의 연도와 계절에 따른 변화를 측정하였다. Keratella 속의 밀도는 봄에 높고 겨울에 낮은 뚜렷한 계절성을 보였다. 군집 내에서 K. cochlearis가 우점종이었으며 상대풍부도는 1995년과 1997년보다 2005년과 2007년에서 높게 나타났다. 연도별 K. cochlearis의 피갑 폭은 유사하였으나, 피갑 길이의 경우 여름에 감소하고 겨울에 증가하는 특징을 보였다. 모든 연도에서 후돌기를 발현하는 개체의 비율이 낮았고 특히 여름과 가을에 출현빈도가 낮았다. 후돌기의 평균 길이는 여름에 짧고 겨울에 길었으며 후두돌기 평균 길이는 겨울에 가장 짧은 것으로 나타났다.