This study aimed to examine the effect of a mild elevation in serum cholesterol level in a porcine coronary overstretch restenosis model using a balloon angioplasty catheter or drug-eluting coronary stent. Pigs were divided into two groups and were fed a commercial normal diet (CND, n = 4) or a high-fat diet (HFD, n = 4) for 5 weeks. Coronary overstretch injury by balloon angioplasty or stent implantation was induced in the left anterior descending and left circumflex artery after 1 week of feeding. Histopathological analysis was performed at 4 weeks after coronary injury. During the experiment, the total cholesterol level in the HFD group increased by approximately 44.9% (from 65.9 ± 3.21 mg/dL at baseline to 95.5 ± 9.94 mg/dL at 5 weeks). The lumen area in the CND group was reduced in comparison with that in the HFD group after balloon angioplasty. After stent implantation, the injury score showed no significant difference. There were significant differences in the neointimal area (2.7 ± 0.33 mm2 in the CND group vs. 3.3 ± 0.34 mm2 in the HFD group, p<0.05), lumen area (2.6 ± 0.54 mm2 in the CND group vs. 2.0 ± 0.33 mm2 in the HFD group, p<0.05), and percent area stenosis (52.0 ± 7.96% in the CND group vs. 62.4 ± 5.15% in the HFD group, p<0.05). Body weight change was not different between the two groups. Increased serum cholesterol level activated vascular smooth muscle cell proliferation in the porcine coronary overstretch model.
최근 서비스 산업이 성장하면서 창업활동이 매우 활성화되고 있다. 창업활동은 경제에 새로운 활력을 불어넣어준다는 측면에서 경제성장에 긍정적인 영향을 미친다고 알려져 있지만 어떤 과정을 통해 경제성장률을 제고시키는지에 대한 연구는 매우 부족한 실정이다. 이에 본 연구에서는 금융시스템의 발전단계에 따라 창업활동이 경제성장에 미치는 영향이 어떻게 달라지는지 분석하였다. 분석대상을 고소득 국가군과 중간소득 국가군으로 구분하여 실증 분석한 결과 창업활동은 모든 분석 국가집단에서 경제성장에 유의한 양(+)의 영향을 미치는 것으로 나타났다. 한편, 금융시스템의 발전단계를 고려한 분석결과에 따르면, 고소득 국가군에서는 창업활동이 시장 중심 금융시스템의 발달과 연계하여 경제성장에 영향을 미치고 있었지만 중간소득 국가군에서는 은행 중심 금융시스템과 상호작용하여 경제성장에 영향을 미치는 것으로 나타났다. 하지만 금융시스템의 발전단계와의 상호작용변수의 추정계수는 유의한 음(-)의 값을 보였다. 이러한 결과는 창업활동이 경제성장에 미치는 긍정적인 효과가 금융시스템의 발전에 의해 오히려 약화된다는 것을 의미한다. 따라서 기존의 금융시스템 외에 창업활동을 지원하는 금융 서비스를 정책적으로 강화하는 것이 매우 중요하다고 여겨진다. 그러나 장기적인 관점에서 정책적으로 직접적인 창업자금을 조달하기보다는 시장을 이용한 자본조달 시스템을 강화하는 한편 창업 실패에 대한 안전장치를 마련하는 등의 추가적인 조치를 취하는 것이 바람직할 것이다.
Entomopathogenic fungus Aschersonia aleyrodis naturally occurred on citrus whitefly, Dialeurodes citri nymph was often observed in organic citrus orchards, Jeju. The genus Aschersonia is also known to be toxic against scale insects and other pests. However, little is known about artificial media for mass production of spores of Aschersonia species. Grains are excellent sources of media for mass conidia production of various entomopathogenic fungi. The yeast extract, which converts carbohydrates to carbon dioxides and alcohols, contains a large amount of vitamin B complexes which facilitate the carbohydrate metabolism. The more yeast extract content the more conidia production on artificial medium made from commercial corn flour and corn gluten feed. The number of conidium produced on oat, millet, sorghum, and unhulled barley medium containing 1% yeast extract were 1.8, 1.8, 1.6, and 2.1×1010/plate (90mm × 15mm), respectively. However, the greatest yeast effect among four media showed appeared on sorghum medium, which produced 25 times higher spore production than sorghum alone. Furthermore, the conidia from solid sorghum medium could be easily harvested with cell scraper.
Aschersonia aleyrodis was well-known to be a biological control agent for citrus whitefly, Dialeurodes citri. This entomopathogenic fungus is naturally occurred in organic farming citrus orchards in Jeju. Both lime-sulfur and Bordeaux mixtures are extensively used today to control citrus diseases like citrus melanose and citrus scab, especially in organic farming pest management program. The high concentrated lime-sulfur is also used for pest control such as pink citrus rust mite and scale insects. This study was focused to test the conidial germination and sporulation of Aschersonia aleyrodis on potato dextrose agar (PDA) medium containing different concentrations of two fungicides. The conidia of Aschersonia aleyrodis grown on PDA mixed with commercial bordeaux mixtures, CM150-505, at dilution rate 1:200 (water : bordeaux mixture) were well-germinated but not sporulated at all. On the other hand, Aschersonia aleyrodis did not sporulate and germinate on lime sulfur treated PDA medium even at extremely low dilution rate 1:2,048,000 (water : lime sulfur). However, when the mycelial cells grown at 25o C for at least 7 days at soluble starch-tryptone medium were added to PDA, they were well-sporulated even at high dilution rate 1:100 (water : lime sulfur). This result suggested that the spore mixtures of Aschersonia aleyrodis should be applied to field quite long after lime-sulfur spray.
본 연구는 아시아, 유럽, 북미지역에서 두 국가간 자본시장과 금융, 자본재, 소비재, 도 ·소매서비스, 공공산업의 두 국가간 자본시장에서 국제차익거래가격결정 모형(IAPM)의 성립여부와 두 국가간 자본시장 통합여부의 결합가설을 검증하였다. 두 국가간 자본시장의 IAPM 성립여부는 요인분석과 다중회귀분석을 실시하였고, 통합여부는 Chow검증으로 분석하였다. 분석결과, 지역별, 산업별 두 국가간 자본시장이 통합되어있다는 가설을 기각할 수 없는 것으로 나와 지역별, 산업별 두 국가간 자본시장이 통합되어 있다고 밝혀졌다. 이와 같은 연구결과는 지역별, 산업별로 통합된 두 국가 자본시장에서 국제분산투자를 실시함으로써 국내분산투자 보다 더 큰 분산투자효과를 얻을 수 있다는 것을 시사한다.
본 연구는 WTO의 출현 등 세계화가 본격적으로 추진되는 시점에서 글로벌 경쟁에 앞선 일본 기업들익 전략적 선택과 우리 나라 기업들의 전략적 선택을 비교분석하므로써 우리 나라 기업들이 글로벌 경쟁에서 승리할 수 있는 방안을 모색하였다. 구체적으로는 한국 제품에 대한 일본 고객들의 평가와 일본 제품에 대한 한국 기업의 평가 비교를 통해 양국 기업들의 전략적 선택을 비교분석함으로써 기계산업이라 는 주요한 산업에 있어서 한국 기업의 세계화를 위한 전략적 시사점을 도출하고자 했다. 실증분석 결과를 보면 국산 기계는 제품의 기능과 서비스 차별화, 마케팅 차별화 등에 있어서 일본의 구매기업들로 부터 낮은 평가를 받고 있다. 국산기계는 가격 면에서만 비교대상인 일본 기계에 대해 높은 평가를 받고 있다. 일본은 제품의 기능과 서비스 차별화, 마케팅 차별화, 기술이전 등 모든 면에 있어서 한국 기업들보다 높은 평가를 받고 있다. 한편 집락분석 결과는 한국과 일본, 양국의 기계 구매업체들은 가격 경쟁력보다는 제품의 기능, 마케팅 차별화, 서비스 차별화, 기술이전과 같은 비가격 경쟁력을 중시한다는 것을 시사한다. 집락분석의 결과는 또한 양국의 기계 구매기업의 입장에서 볼 때 재구매 의사 결정은 비가격 경쟁력의 어느 한 차원과만 관련되어 있는 것이 아니라 비가격 경쟁력의 모든 차원과 관련되어 있음을 시사한다. 집락분석의 결과는 비가격 경쟁력의 어느 한 측면에서 높게 평가받는 집락이 다른 측면에서도 높게 평가받고 있음을 보여 준다. 회귀분석 결과는 한국과 일본, 양국에서 제품의 기능과 마케팅 차별화가 구매기억의 재구매 의사결정에 영향을 미친다는 것을 시사한다.
This study was carried out to determine the amount of lignin, cellulose, and hemicellulose in six kenaf cultivars during different harvesting stages. Three mutant cultivars (Jangdae, Jeokbong and Baekma), two original cultivars (Jinju, C14), and one Chinese cultivar (Auxu) were planted on May 14, 2013. Four harvesting times were made at intervals of 20 days from 15 July to 16 September, 2013. The overall growth characters of mutant cultivar ‘Jeokbong’ such as plant height, stem diameter, flowering time, and dry mass were similar with those of the original variety. The mutant cultivar ‘Baekma’ occurred 10-day late flowering in comparison with the original variety and also displayed higher dry mass than the original variety. Jinju, Auxu and Jangdae, mid-late maturing kenaf cultivars, had high dry weight compared to early maturing cultivars such as Jeokbong, Baekma and C14. In all cultivars, the lignin contents were increased by a late harvest. The Mid-late maturing kenaf cultivars showed high lignin content in comparison with those of the early maturity cultivars. There were no significant differences of cellulose, and hemicellulose content between the cultivars, however cellulose content in stems of these kenaf cultivars were significantly decreased by a late harvest. These results may provide valuable information to assist the parental selection of kenaf breeding.
Radiation technologies have been widely used in mutation breeding of crops. Although gamma-radiation has been predominantly applied in radiation breeding, ion beam irradiation is recently emerging as a methodology highly effective in induction of mutations that are useful for plant breeding. Therefore, we investigated the biological effects caused by irradiation of two types of ion beams, which were proton and ion beams, respectively, in pepper. In the evaluation of survival rate, LD50 values were between 300 and 350 Gy, 30 and 40 Gy in irradiation of proton and carbon beams, respectively, while LD50 for gamma-ray was determined to be between 50 and 100 Gy. Growth traits including shoot length, root length, and root width were also examined in pepper seedlings according to does of proton and carbon ion beams to estimate biological effectiveness of each radiation. The result was applied in the construction of pepper mutant population which will be used to develop pepper breeding materials containing novel characteristics.
For QTL analysis of agronomic traits based on cultivation of low and high altitude locations, BC1 F5 181 lines were developed from a cross of Tongil type Gayabyeo and japonica Chhomrong originated from Nepal. Plant materials were grown in both of low altitude area of Milyang, Korea and high altitude area of Khumaltar, Nepal. In QTLs analysis, a total of 42 QTLs were detected in days to flowering, culm length, panicle length, number of panicles/hill, panicle exertion, and spikelet ripening ratio. Although many of the QTLs were coincided between the two locations of Korea and Nepal, several QTLs were revealed as location specific in high altitude area of Khumaltar. Especially, the regions harboring marker RM489-RM14281 on chromo- some 3, RM5642-RM19049 on chromosome 5, and RM2854-RM6696 on chromosome 12 where QTLs were clustered and coincided between the two locations are considered as positive target regions for environmental independent traits. Furthermore, high rate of location specific QTLs such as panicle exertion and spikelet ripening ratio could be considered carefully for understanding the mechanism of cold tolerance based on cultivation of different altitude location.
An unbalance of rice productions and consumptions caused serious problems in both of agricultural area and grain market of korea. In recently, various efforts for rice processing products such as rice noodles and rice wines are in progress to overcome the unstable rice market. Among them, waxy rice is predominant items in processing rice. However, varietal features of starch viscosity are not considered in the processing industries and rice breeding field. In this study, 12 waxy rices and 2 cultivars Ilmibyeo(japonica) and IR72(Indica) were studied for physicochemical and amylogram to characterize the use of waxy rices. The amylose contents of waxy rices were from 7.1 to 8.1% with soft gel consistency and relatively low alkali digestion value(1.4% KOH) compare to Ilmibyeo. In the amylogram analysis(RVU) of waxy rices, unlikely normal rices, very fast peak time(about 3.5 min.) was obtained compare to that of 6.2 min. of Ilmibyeo. And 2 to 3 groups were classified based on peak viscosity and consitency of RVU. Wangchal, Odorokimochi and Hangangchal showed relatively high peak viscosity seemed not suitable for rice cake due to the hardness speed. And most of waxy rices developed in korea were believed to be suitable for oil fried cakes(Hankwa) because of a certain grade of starch degradation speed. And Mochiminori and Midoromochi originated from japan could be a good sources in waxy rice breeding program to improve the cooking properties especially in slow down of hardness speed with very low peak viscosity, hot viscosity and cool viscosity.