Abstract Purpose : This study investigated the impact of knowledge and awareness of perception of harmful rays on the use of blue light blocking lenses among university students majoring in optometry. Methods : This study targeted 65 optometry students who responded to an online survey from September 2023 to October 2023. The survey used a survey tool with a total of 15 questions, including knowledge and awareness of perception of harmful rays and demands for guidelines. Statistical analysis was performed using SPSS 19.0. Results : The overall knowledge score about UV rays and blue light was 14.00±3.10 for optometry students and 12.30±3.50 for general university students, showing that the optometry students had higher knowledge (p<0.001). In the case of use of UV-blocking lenses, 70.8% of optometry students were found to be using them, which was higher than 51.5% of general university students. The use of glasses to block blue light was found to be 41.5% of optometry students and 36.9% of general university students. The correlation between perception of the importance of blocking harmful rays and the need for guidelines for the correct selection of blue light blocking lenses was r=0.528 (p<0.001). Conclusion : Optometry students' knowledge and perception of harmful rays were found to be higher than those of general university students, and it appears to have an impact on the use of harmful ray-blocking lenses. Therefore, it is necessary to strengthen education and establish guidelines for the correct selection of harmful ray blocking lenses.

목적: 본 연구는 COVID-19의 대유행 동안 20~30대 성인을 대상으로 컴퓨터시각증후군 (CVS, computer vision syndrome) 관련 눈의 자각증상과 시력 관련 불편감을 파악하고, 눈 건강을 위해 사용하는 예방법을 알아보고자 하였다. 방법 : 2021년 12월부터 2022년 2월까지 안경 또는 콘택트렌즈 처방과 상담을 위해 일개 안경원에 내원 했던 20~30대 성인 중에서 전신질환 및 안질환, 안과적 수술 경험이 없는 150명을 대상으로 하였다. 연구도구는 대상자의 일반적인 특성(3문항), CVS 자각증상(16문항), 시력 관리(2문항), 눈의 조절기능 이상(2문항), 청색광 차단 안경사용(2문항), 근거리교정(1문항)으로 총 26문항으로 구성된 설문지를 이용하였다. 결과 : 전체 대상자들의 CVS 자각증상은 “눈물이 많이 발생한다”가 109명(72.7%)으로 가장 높은 빈도를 보였 고, 그다음은 “눈이 아프다”가 104명(69.3%)으로 나타났다. CVS 자각증상 중 시력 관련 자각증상은 “사물이 흐 려보인다”가 106명(70.7%)으로 가장 많았다. 시력 관리방법으로는 “시력의 저하를 느껴서”가 105명(70.0%)으로 가장 많았고, 청색광 차단 안경 사용하는 대상자는 150명(84.7%)으로 80% 이상의 대상자들이 기능을 넣어서 사 용하고 있다. 결론 : CVS 자각증상 16문항 중 14문항에서 50% 이상으로 나타났다. 청색광 차단 안경을 사용하지 않는 대상 자는 CVS 자각증상 중 시력과 관련된 “시력이 나빠지는 것 같다”가 69.6%로 가장 높게 나타났다. COVID-19 대 유행 동안 자각적인 불편증상과 시력저하를 호소하는 대상자가 높게 나타나고 있다. 따라서 안경처방 시 생활환 경, 사용시간 및 자각적 증상에 대하여 문진이 필요하다고 생각된다.

목적: 대학생을 대상으로 자외선을 포함한 청색광과 같은 유해광선에 대한 지식과 인식도를 알아보고자 하였다. 방법 : 2023년 4월부터 5월까지 온라인 설문 조사에 응답한 충남지역 대학생 103명을 대상으로 하였다. 설문 은 대상자의 일반적 특성에 관한 문항, 자외선과 청색광 차단렌즈의 착용실태에 대한 문항, 자외선과 청색광에 대 한 지식도 및 인식도 문항, 그리고 차단렌즈 선택을 위한 가이드라인의 요구도 문항으로 구성된 총 15문항의 설문 도구를 사용하였다. 통계분석은 SPSS 18.0을 사용하였다. 결과 : 자외선 차단을 위해 안경이나 콘택트렌즈를 착용하는 비율은 56.3%로 나타났으나 청색광 차단 안경이 나 콘택트렌즈를 사용하는 경우는 35.9%로 상대적으로 낮은 비율로 나타났다. 자외선과 청색광의 유해성에 관한 지식도는 각각 2.58±0.91, 2.44±0.98로 조사되었으며, 자외선과 청색광으로부터 눈 보호가 중요하다고 생각하 는 항목의 평균 점수는 각각 3.49±0.61, 3.35±0.68점으로 조사되어 자외선과 청색광 차단의 중요성에 대한 인 식도는 높은 것으로 나타났다. 결론 : 대학생들의 자외선과 청색광에 대한 지식도와 인식도는 높은 수준이었으나 청색광 차단렌즈에 올바른 선택법에 대한 지식은 낮은 수준을 나타냈다. 이에 청색광 차단렌즈의 올바른 선택을 위한 교육 강화와 가이드라 인의 구축이 필요할 것으로 판단된다.

본 연구에서는 상용화된 로프절단장치 타입 중 국내에 가장 많이 도입되어있는 Scissor type을 대상으로 유한요소해석을 수행하여 다양한 로프 걸림 상황에서 안정성이 확보되는 적합한 구조 형태를 평가하였으며, 수조 실험 및 실선 실험을 통해 효용성을 검증하였다. 연구 결과, 로프 걸림에 의하여 프로펠러축이 회전하지 않을 경우 엔진에서 발생하는 지속적인 토크로 인하여 로프절단장치에 비틀림이 발생하고 유한요소 해석상 자유도가 구속되어 있지 않은 하부의 블레이드에서 가장 높은 변형이 발생하는 것을 확인하였다. 블레이드의 두께가 증가할수록 최대변형량은 줄어들고 최대응력은 낮아져 안전율이 증가하는 결과가 나타났으며, 동일한 블레이드 두께에서 토크의 변화량이 최대응력과 최대변형량에 미치는 영향은 로프절단장치의 외력이 미치는 위치와 무관하며 정비례하게 감소하는 것으로 나타났다. 해석 결과를 토대로 실시한 수조실험 및 실선실험 결과, 모든 조건과 환경에서 로프 및 어망이 원활하게 제거되는 것을 확인하였다.

Hydrogen energy is expanding in range for civil use together with development of pollution-free power sources recently, and it is judged that the use of hydrogen will increase more as a part of carbon dioxide reduction measures according to the Climatic Change Convention. Especially, it is thought that the securement of safety of the used dispenser will be the biggest obstacle in the use of high-pressure hydrogen because the hydrogen station is operated in a high pressure. This study found risks in the process and problems on operation by making use of HAZOP(6 kinds), a qualitative safety evaluation technique, and FMEA(5 kinds), a fault mode effect analysis, for the hydrogen charging system at a hydrogen gas station, derived 6 risk factors from HAZOP and 5 risk factors from FMEA, and prepared measures for it.

For the hydrogen economy system being tried starting with the 21st century, the fields that was not dealt with so far, such as the safety measure for large leakage accidents, the safety problem at infrastructures like a hydrogen station, the safety problem in terms of automobiles depending on introduction of hydrogen cars, the safety problem in a supply for homes like fuel cells, etc., are being deeply reviewed. In order to establish a safety control system, an essential prerequisite in using and commercializing hydrogen gas as an efficient energy source, it is necessary to conduct an analysis, such as analysis of hydrogen accident examples, clarification of physical mechanisms, qualitative and quantitative evaluation of safety, development of accident interception technologies, etc. This study prepared scenarios of hydrogen gas leakage that can happen at hydrogen stations, and predicted damage when hydrogen leaks by using PHAST for this.

Muscle satellite cell (SC) is responsible for postnatal muscle growth, repair, and regeneration. Satellite cell is an im-portant source of multi-potent stem cell process and differentiation into adipogenic, myogenic, and osteoblastogenic. The objective of this study was to identify alter of transcriptome during differentiation in porcine satellite cell and to elevated transcriptome at different stages of postnatal development to gain insight into the differences in differ-entiated PSC. We used RNA-seq technique to investigate the transcriptomes during differentiation in pig muscle. Sequence reads were obtained from Illumina HiSeq2000. Differentially expressed genes (DEG) were detected by EdgeR. Gene ontology (GO) terms are powerful tool for unification among representation genes or products. In study of GO biological terms, functional annotation clustering involved in cell cycle, apoptosis, extracellular matrix, phosphoryla- tion, proteolysis, and cell signaling in differences stage. Taken together, these results would be contributed to a better understanding of muscle biology and processes underlying differentiation. Our results suggest that the source of DEGs could be better understanding of the mechanism of muscle differentiation and transdifferentiation.

Satellite cells were derived from muscular tissue in postnatal pig. Satellite cell is an important to growth and development in animal tissues or organs. However, the progress underlying induced differentiation is not clear. The aim of this study was to evaluate the morphologic and the transcriptome changes in porcine satellite cell (PSC) treated with insulin, rosiglitazone, or dexamethasone respectively. PSC was obtained from postnatal muscle tissue. In study 1, for study the effect of insulin and FBS on the differentiated satellite cells, cells were cultured at absence or presence of insulin treated with FBS. Total RNA was extracted for determining the expression levels of myo-genic PAX3, PAX7, Myf5, MyoD, and myogenin genes by real-time PCR. Myogenic genes decreased expression levels of mRNA in treated with insulin. In study 2, in order to clarify the relationship between rosiglitazone and lipid in differentiated satellite cells, we further examined the effect of FBS on lipid accumulation in the presence or absence of the rosiglitazone and lipid. Significant differences were observed between rosiglitazone and lipid by FBS. The mRNA of FABP4 and PPARγ increased in rosiglitazone treatment. In study 3, we examined the effect of dexame-thasone on osteogenic differentiation in PSC. The mRNA was increased osteoblasotgenic ALP and ON genes treated with dexamethasone in 2% FBS. Dexamethasone induces osteoblastogenesis in differentiated PSC. Taken together, in differentiated PSCs, FABP4 and PPARγ increased to rosiglitazone. Whereas, no differences to FBS and lipid. These results were not comparable with previous reports. Our results suggest that adipogenic, myogenic, and osteoblasto-genic could be isolated from porcine skeletal muscle, and identify culture conditions which optimize proliferation and differentiation formation of PSC.

Muscular satellite cell (SC), which is stem cell of postnatal pig, is an important for study of differentiation into adipogenesis, myogenesis, and osteoblastogenesis. In this study, we isolated and examined from pig muscle tissue to determine capacity in proliferate, differentiate, and expression of various genes. Porcine satellite cells (PSC) were isolated from semimembranosus (SM) muscles of 90∼100 days old pigs according to standard conditions. The cell proliferation increased in multi-potent cell by Masson’s, oil red O, and Alizarin red staining respectively. We per-formed the expression levels of differentiation related genes using real-time PCR. We found that the differentiation into adipocyte increased expression levels of both fatty acid binding protein 4 (FABP4) and peroxisome proliferator- acti-vated receptor gamma (PPARγ) genes (p<0.01). Myocyte increased the expression levels of the myosin heavy chain (MHC), myogenic factor 5 (Myf5), myogenic regulatory factor (MyoD), and Myogenic factor 4 (myogenin) (p<0.01). Osteo-blast increased the expression levels of alkaline phosphatase (ALP) (p<0.01). Finally, porcine satellite cells were indu-ced to differentiate towards adipogenic, myogenic, and osteoblastogenic lineages. Our results suggest that muscle satellite cell in porcine may influence cell fate. Understanding the progression of PSC may lead to improved strat-egies for augmenting meat quality.

This study aims to identify DNA marker related to health index which is derived from fatty acid composition of Hanwoo meat. We investigated a genetic association between two SNPs (-867G>C and 878C>T) of SCD gene and health indexes. Two health index values (index of atherogenicity and index of thrombogenicity) were derived from a combination of fatty acid composition. Phenotypic correlation indicated that oleic acid (C18:1) was negatively correlated to index of atherogenicity (-0.84) and index of thrombogenicity (-0.91), respectively. Statistical analysis revealed that 878T>C SNP was significantly associated with IA (index of atherogenicity, p=0.012) and IT (index of thrombogenicity, p=0.006). There was no association between the regulatory SNPs (-867G>C and -877Gdel) and health indexes. Haplotype analysis detected 4 main haplotype (GdelT; 0.004, GdelC; 0.344, CGT; 0.350 and CGC; 0.261) in Hanwoo. The GdelT haplotype was significant on IA and IT. The effect of GdelT haplotype showed increasing IA and IT values, while GdelC haplotype has a decreasing IA and IT value in Hanwoo. In conclusion, the 878C>T SNP in the SCD gene seems to have an effect on this health index and might be implemented into animal breeding program.

치과 콘빔 전산화단층 검사 시 갑상선 부위의 방사선 피폭선량을 최소화하기 위하여 보루스 (Bolus)를 이용한 차폐체를 제작하고, 방사선 차폐 효과와 영상의 적정성을 평가하였다. 치과용 콘빔 전산화단층검사 장비를 사용하여 치과방사선 두부 팬텀을 대상으로 갑상선의 좌, 우측 부위에 유리선량계를 부착시켜 방사선량을 측정하였다. 차폐체의 두께를 각각 10 mm, 20 mm, 30 mm로 다르게 하여 각 차폐체별로 흡수선량을 측정하여 차폐체를 사용하지 않았을 경우와 비교하였다. 8명의 평가자가 진료영상의 적정성을 여부를 평가하였다. 왼쪽 갑상선 부위에 30 mm Bolus 차폐체를 사용한 경우에는 결과값이 평균 342.67 μ㏉로 Bolu s 차폐체를 사용하지 않고 측정한 결과값의 평균 431.22 μ㏉보다 20.7% 감소하였고, 오른쪽 갑상선 부위에 30 mm Bolus 차폐체를 사용한 경우에는 평균 424.56 μ㏉로 21.9%의 선량감소효과를 보였다. 진료 영상의 적정성은 평가자 모두 사용 가능하다 판단하였다. 결론적으로, 치과 콘빔 전산화단층검사 시 갑상선 부위의 방사선 피폭선량을 최소화하기 위해 제작된 Bolus 차폐체는 장해음영 없이 적정한 진단 영상 처리가 가능하고, 방사선차폐 효과가 있어 유용한 차폐체로 적용 가능할 것으로 사료된다.

Atrial fibrillation (AF) is a common, benign, and transient type of supraventricular arrhythmia encountered during the early postoperative period after a pulmonary resection. However, it sometimes might result in hemodynamic deterioration. We report on a case of new-onset atrial fibrillation in a 74-year-old male patient after right lower lobectomy, which was not controlled with intermittent bolus injection of esmolol and diltiazem. Successful pharmacological cardioversion was achieved with intravenous (6 mg/hr for 2 hours) followed by oral (90 mg q day) diltiazem 20 hours after this treatment. The literature on the risk factors and management of atrial fibrillation after pulmonary resection is reviewed.

Central venous catheterization can induce cardiac arrhythmias, such as, premature atrial or ventricular complexes, which are typically transient events. However, sometimes it initiates supraventricular tachycardia (SVT) with hemodynamic repercussions. We present a case of supraventricular tachycardia with cardiovascular collapse during central venous catheterization in a 32-year-old woman with an ovarian mass who required exploratory laparotomy. At first, the guide wire was withdrawn and carotid sinus massage attempted, but the patient did not return to sinus rhythm. Eventually, reversion to sinus rhythm was achieved after injecting adenosine.