The objective of the present study was to estimate the health risk level for children exposed to phthalate and identify the pathways including indoor floor dust, surface wipe and hand wipe in elementary-schools and institutes. The samples of indoor place were collected at children's facilities (50 elementary-schools and 46 academies) in summer (Aug ~ Sept, 2008), winter (Dec 2008 ~ Feb, 2009) and Spring (Mar ~ Apr, 2009) periods. Hazard Index (HI) were estimated for the non-carcinogens and the examined phthalate were diethylhexyl phthalate (DEHP), dibutyl-n-butyl phthalate (DnBP), butylbenzyl phthalate (BBzP). Risk analysis indicates that did not exceed 0.01 (HI) for all subjects in all facilities it's 50^th % and 95^th % value. For DEHP, DnBP and BBzP their detection rates through multi-pathways were high and their risk based on health risk assessment was also observed to be acceptable.

The aim of this study was to calculate the health risks which children were exposed to trace metals through several pathways including air, floor dust, wipe and hand wipes in elementary-schools and academies. The samples were collected at children's facilities (50 elementary-schools and 46 academies) in summer (Aug ~ Sept, 2008), winter (Dec 2008 ~ Feb, 2009) and Spring (Mar ~ Apr, 2009) periods. The lifetime Excess Cancer Risks (ECRs) were estimated for carcinogen trace elements such as As, Cd, and Cr. For carcinogens, the Excess Cancer Risk (ECR) was calculated by considering the process of deciding Cancer Potency Factor (CPF) and Age Dependent Adjust Factor (ADAF) of the data of adults. Hazard Quotients (HQs) were estimated for the non-carcinogens trace metals like Cd, Cr, Hg and Pb. The average ECRs for young children were 1×10^-9~1×10^-8 (50%th percentile) level in all facilities. Non-carcinogens did not exceed 0.1 for all subjects in all facilities. For trace metals their risk based on health risk assessment was also observed to be acceptable.

Risk Assessment, a basis of health and safety management system, is an calamity prevention activity which regularly measure the level of a risk to passively improve potential hazard. A problem, the assessment not being improved to be applied to the construction work site where requires diversity and complexity, causes the assessment to be inefficient to bring quality results. A study on the investigates and compares the surveyed degree of recognitions of workers who works in companies executing the risk assessment By the investigation and comparison, it is expected to bring the better solution for early and efficient application for those companies which are not taking the risk assessment.

The purpose of this study was to investigate the health risk and management of childhood exposure to indoor aldehydes in elementary-schools and academies. The samples were collected at children's facilities (50 elementary-schools and 46 academies) in summer (Aug ~ Sept, 2008), winter (Dec 2008 ~ Feb, 2009) and Spring (Mar ~ Apr, 2009) periods. The overall mean concentration of formaldehyde was 68.3 ㎍ /m³ and 27.2% of exceeded the 100 ㎍/m³ by the school health guideline. The concentration ratio of Indoor air and outdoor air (I/O) of aldehydes exceeds 1.0. The level of indoor air contamination did appear to be high, and 24.6% of the academies evaluated had exceeded the formaldehyde level specified by the public health act (120㎍ /m³). We estimated the lifetime excess cancer risks (ECRs) of formaldehyde, and the hazard quotients (HQs) of non-carcinogens (acetaldehyde and benzaldehyde). In addition, for carcinogens, the excess cancer risk (ECR) was calculated by considering the process of deciding cancer potency factor (CPF) and age dependent adjust Factor (ADAF) of the data of adults. The average ECRs of formaldehyde for young children were 1×10^-6~1×10^-5 level in all facilities. HQs of formaldehyde did exceed 0.1 for all subjects in elementary school.

This study was to assess the lifetime cancer and non-cancer risk on exposure to volatile organic compounds This study was assessed the lifetime cancer and non-cancer risk of volatile organic compounds (VOCs) exposure in young children at elementary-schools and academies in Korea. The samples were collected at children's facilities (50 elementary-schools and 42 academies) in summer (Aug ~ Sept, 2008), winter (Dec 2008 ~ Feb, 2009) and Spring (Mar ~ Apr, 2009) periods, and analyzed by GC-MSD. We estimated the lifetime excess cancer risks (ECRs) of benzene and the hazard quotients (HQs) of non-carcinogens toluene, ethylbenzene, xylene and styrene. In addition, for carcinogens, the excess cancer risk (ECR) was calculated by considering the process of deciding cancer potency factor (CPF) and age dependent adjust Factor (ADAF) from the data in adults. The average ECRs of benzene for young children were 1×10^-7~1×10^-9 level in all facilities. HQs of four non-carcinogens did not exceed 1.0 for all subjects in all facilities.

This study was to assess the lifetime cancer and non-cancer risk on exposure to volatile organic compounds (VOCs) and formaldehyde of worker and user at public facilities in Korea. We measured the concentrations of formaldehyde and VOCs in indoor air at 160 public buildings that 5 kinds of public facilities (30 hotel, 30 fitness center, 25 gosiwon, 30 reading-room and 45 video-room) all over the country. There were estimated the human exposure dose and risks with averages of the using-time and frequency for facility users and office workers, respectively. Carcinogens (benzene and formaldehyde) were estimated the lifetime excess cancer risks (ECRs). Non-carcinogens (toluene, ethylbenzene, xylene, and styrene) were estimated the hazard quotients (HQs). HQs of four non-carcinogens did not exceed 1.0 for all subjects in all facilities. Higher HQs of toluene were observed at the reading-room. The average ECRs of formaldehyde and benzene for facility worker and user were 1×10^-4~1×10^-6 level in all facilities. The estimated ECRs for reading-room were the highest and the fitness center and gosiwon were the next higher facilities. Because lifetime ECRs of carcinogens exceeded 1×10^-4 for facility worker in the most facilities, risk management of formaldehyde and benzene in the facilities was necessary. IAQ guidelines should be determined strictly to prevent occurrence of disease caused by poor IAQ beforehand.

This study assessed the health risk of trace elements in indoor children-facilities by multi-pathway measurements (Air, Dust, Wipe, Hand washing). The samples of indoor place were collected at various children's facilities (40 day-care houses, 42 child-care centers, 44 kindergartens, and 42 indoor playgrounds) in summer (Jul~Sep, 2007) and winter (Jan~Feb, 2008) periods, and analyzed by ICP-MS. The lifetime Excess Cancer Risks (ECRs) were estimated for carcinogen trace elements such as As, Cd, Cr and Ni. For carcinogens, the Excess Cancer Risk (ECR) was calculated by considering the process of deciding Cancer Potency Factor (CPF) and Age Dependent Adjust Factor (ADAF) of the data of adults. Both Hazard Quotients (HQs) and Hazard Index (HI) were estimated for the non-carcinogens and children sensitivity trace elements like Cd, Cu, and Cr. The average ECRs for young children were 1×10^-10~1×10^-6 (50%th percentile) level in all facilities. Non-carcinogens and Children's sensitivity materials did not exceed 1.0 (HQs, HI) for all subjects in all facilities. For trace elements their detection rates through multi-pathways were not high and their risk based on health risk assessment was also observed to be acceptable. In addition, through education on the risk of multi-pathway exposure of trace elements for managers of facilities as well as for users the risk control of exposure of children.

Domestic studies for identification of causality between children exposure to toxic chemicals, such as arsenic (As) and resulted hazardous effects were not implemented. This study was conducted to probabilistically estimate dietary As intake and health risk assessment for young children and all age-specific populations from the consumption of As-contaminated rice of Korea. Arsenic intakes for young children (1 to 6 years old) from As-contaminated rice were higher than other age-specific groups, based on a dose-per-body weight basis. Based on the current EPA cancer slope factor for As, estimated cancer risks (to the skin cancer) associated with dietary intake of As-contaminated rice for 1 to 2 years old group and 3 to years old group are 1.76 per 10,000 and 3.16 per 10,000, respectively, at the 50th percentile. Based on possible reference levels (0.005 mg/kg/day) for children, mean and 95th percentile value of HQ from rice for young children are very below 1.0, which is a regulatory limit of non-carcinogenic risks for human.

Chronic exposure to Arsenic (As) causes significant human health effects including various cancers. Total As concentrations from 300 polished rice samples cultivated near the mining areas in Korea were analyzed to estimate a probabilistic assessment of human health risk from As-contaminated rice. The mean of total As concentrations in rice was 0.09 mg/kg and lognormal distribution model was set for total As concentrations. Human health risk for As in rice was estimated using gender-specific rice consumption data and average daily dose (ADD). While cancer risk (CR) and hazard quotient (HQ) were calculated using oral cancer slope factor (OCSF) and Reference dose (RfD) suggested by the U.S. EPA. Mean of CR posed by total As was 2.16 (for male) and 1.83 (for female) per 10,000. The HQ for general population from rice cultivated near the mining areas in Korea was below 1 as the 50th percentile of general population. However, less than 10% of general population consuming rice cultivated near the mining areas would exceed 1.0. This result is similar with those from each gender-specific group.

This study was performed to investigate the concentration of indoor aldehydes in children’s facilities. The samples were collected from various children's facilities (40 playrooms, 42 day-care centers, 44 kindergartens, and 42 indoor playgrounds) in summer (Jul~Sep, 2007), winter (Jan~Feb, 2008) and spring (Mar~Apr, 2008). The ratio of Indoor and outdoor (I/O) of aldehydes exceeds 1.0 and the formaldehyde levels in each child-care facilities were significantly different. We evaluated the lifetime cancer and non-cancer risk of young children due to indoor aldehyde exposure. We estimated the lifetime excess cancer risks (ECRs) of formaldehyde, acetaldehyde and the hazard quotients (HQs) of non-carcinogens (benzaldehyde and formaldehyde). Formaldehyde was evaluated for both carcinogenic and non-carcinogenic risk. The average ECRs of formaldehyde for young children were 1×10^-4~1×10^-5 level in all facilities. HQs of four non-carcinogens did not exceed 1.0 for all subjects in all facilities.

본 연구는 성인남성 수형자 208명과 가정폭력사범 103명을 대상으로 성장기 의 지역사회폭력과 가정폭력의 피해경험, 고위험 환경이 정신건강과 범죄행위 에 영향을 주는지 살펴보았다. 구체적으로, 수형자와 폭력남편들의 정신건강 부 적응 양상을 비교하고, 정신건강 부적응 수준에 과거의 어떤 형태의 외상이 영 향을 주는지 조사하였다. 또 수형자 집단을 대상으로 소년범죄력 유무에 따라 정신건강과 성장기 외상경험이 어떻게 다른지 확인해 보았다. 나아가 수형자와 가정폭력 행위자의 재범행위와 관련된 요인은 무엇인지 찾아보았다. 끝으로 지 역사회폭력 노출의 예측요인을 탐색하였다. 수형자들의 정신건강 부적응에 영 향을 주는 요인은 고위험 환경인 것으로 나타났다. 반면 폭력남편들에게는 지 역사회폭력의 피해경험이 정신건강에 역기능적으로 작용하고 있었다. 소년범죄 경력이 있는 수형자들과 없는 수형자들은 성격특질에서 뚜렷한 차이를 보였다. 소년사건에 연루되었던 수형자들은 상대집단에 비해 반사회성, 건강염려증, 분 열증, 강박증, 히스테리, 우울증이 높았고, 성장과정에서 겪은 외상도 더 심각하 였다. 지역사회나 가정에서의 폭력노출은 수형자들의 실형재범에 영향을 주지 않는 것으로 밝혀졌다. 대신 소년범죄력이 실형재범과 밀접하게 관련되어 있었 다. 가정폭력사범들 경우, 지역사회폭력 피해경험이 폭력범죄를 되풀이하게 하 는데 기여하고 있었다. 지역사회폭력 피해의 예측변수는 자녀폭력 피해경험으 로 조사되었다. 수형자 집단에서는 고위험 환경이 또 다른 예측변수로 발견되었 다. 지역사회폭력 목격을 예견하는 요인은 수형자, 가정폭력 행위자 모두에게서 고위험 환경인 것으로 확인되었다.

To provide the research strategy for protection of children’s health from hazardous chemical, we reviewed the hazardous chemicals can be exposed through maternity, children's life style and living environment. Recently, diseases related with children’s living condition were focused as asthma, atopy, childhood developmental disability, congenital malformations and obesity. Children can be exposed to hazardous chemicals through an ambient air, water, soil, food, toys and other factors such as floor dust. Also children’s health was deeply related with a wrong life style and neglectful caring by a lack of knowledge and information of harmful ones at parents and child care center’s nursers. According to the previous study, the chemical risk factor of children’s health were identified as inorganic arsenic, bisphenol A, 2,4-D, dichlorvos, methylmercury, PCBs, pesticide, phthalates, PFOA/PFOS, vinyl chloride, et al. Domestic studies for identification of causality between children exposure to chemicals and resulted hazardous effects were not implemented. The confirmation of chemical risk factors through simultaneously performing toxicological analysis, human effect study, environmental/human monitoring, and risk assessment is needed for good risk management. And also, inter-agency collaboration and sharing information can support confirming scientific evidence and good decision making.

This study was to assess the health risk of VOCs in indoor air under uncontrolled Korean-IAQ regulation. We measured the concentrations of formaldehyde and 5 VOCs (benzene, toluene, ethylbenzene, xylene, and styrene) in indoor air at 232 public buildings for four kinds of public facility (32 wedding halls, 17 Gymnasiums, 20 Galleries, and 166 Welfare facilities) around the country. There were estimated the human exposure dose and health risk used average time and frequencies of questionaries for subjects such as facility users and office workers. There were estimated the lifetime excess cancer risk (ECR) for carcinogens (formaldehyde and benzene) and hazard quotient (HQ) for non-carcinogens (toluene, ethylbenzene, xylene and styrene). For the facility user, the average levels of ECRs were 10-4∼10-5 and 10-5 ∼10-6, respectively, for formaldehyde and benzene in all facilities. HQs of four non-carcinogens were not exceeded 1.0 in all facilities and subjects. In addition, there was showed the highest ECR in the smoking facility.

For indoor air quality at a newly built apartment before move-in, we monitored formaldehyde and VOCs and assessed human exposure and probabilistic health risk. We selected 801 newly built apartments all over the country. The results of the research on the condition show the mean concentrations of formaldehyde 294 ㎍/㎥, 210(median) 1497㎍/㎥(maximum), benzene 6㎍/㎥, (4 and 92㎍/㎥), toluene 1003㎍/㎥(773 and 5013 ㎍/㎥), ethylbenzene 120㎍/㎥, (62 and 1192㎍/㎥), xylene 287㎍/㎥(138 and 2723㎍/㎥) and styrene 64㎍/㎥, (42 and 531㎍/㎥). Formaldehyde from carcinogen and toluene and xylene from non-carcinogen were assessed the risk for human health. The excess cancer risk of formaldehyde for human beings between carcinogens is per 1.36 of average 1000 persons. This implies that it is over a level per 1.00 of 1000 persons demanding active risk reduction. Hence, we strongly need the active reduction plan and accurate source assumption. Among a variety of factors affecting indoor air quality for householders, closing construction or density of indoor air processing additional interior construction and indoor area, indoor air quality with a variety of districts show significant. The excess cancer risk for human beings of formaldehyde between carcinogens is per 1.36 of average 1000 persons. Non-carcinogen toxicity rate for human-beings with toluene and xylene among non-carcinogens is over HQ 1 from Seoul to local area.

This study performed and re-analysed the articles of exposure assessment for the indoor environment of houses in many environment-related journals published. in Korea since 1990. Based on this comparative study, we estimated the unit health risk on indoor environment. The objective of this study was to offer scientific data for decision-making policy for improvement and management of indoor air quality on Korean house in. The pooled concentrations for the critical air pollutants in the house were 13.93±13.91㎍/m3 (PM10), 680±226 ppm for (CO2), 1.9±1.6 ppm (CO), 419±158 CFU/m3 (bacteria), 0.036 ± 0.002 ppm (NO2), and 104.935 ± 16.424 Bq/m3 (Rn), The pooled concentrations for the volatile organic compounds were 6.9±6.7㎍ /m3 (benzene), 39.3±55.1㎍/m3 (toluene), 4.2±4.0㎍/m3 (ethylbenzene), 11.4±8.3㎍/m3 (m, p-xylene), 4.2 ±1.5㎍/m3 (styrene) and 6.3±4.5㎍/m3 (o-xylene). The unit cancer risk for men and women by inhalation of benzene was 3.7 × 10-5 and 4.8 × 10-6, respectively. In additio

Currently, Ministry of Environment has promulgated and executed 'the legislation of indoor air quality for public facilities' but the data of indoor air pollutant for public facilities of this law was very insufficient. Therefore, collection of data for indoor air pollutants and execution for risk assessment in order to offer scientific data for decision-making of policy to present reasonable standards and preventive techniques of engineering were required. Therefore, this study collected and re-analysed the articles of exposure assessment for indoor environment in journals related environment in Korea since 1990 and estimated the safety factor on residents in public facilities. The objective of this study was to offer scientific data for decision-making of policy for improvement and management of indoor air quality in Korea. As the results of this study, the risk assessment for the critical pollutants in CTE (central tendency exposure) showed that safety factors according to pollutants were less than 1 which means safe level in micro-environments. It was investigated that the safety factors of CO in hospital, NO2 in terminal, PM10 and NO2 in subway station respectively were over than 1 in RME (reasonable maximum exposure). Through the results, it was investigated that health risk by inhalation of criteria and guideline air pollutants in domestic public facilities was not high. It should be considered effect of inhalation by other hazardous air pollutants because this study was examined just partial pollutants. Presentation of scientific data for expansion of study is requisite and active research of health risk assessment about indoor air quality.

There has recently become one of the major concern expressed the general public and regulation agencies concerning health risks associated with indoor air pollution in Korea. A new indoor air quality program under "Legislation of Indoor Air Quality Management for Public Facilities" is enforced to act on the end of May, 2004 by the Korea Ministry of Environment. The purposes of this article were to discuss the sustainable development of indoor air pollution and to strengthen the importance of the sustainability of indoor air quality. Sustainable development is development that meets the needs of the present without compromising the ability future generations to meet their own needs and a new theory that grew out of the conservation / environmental movement of the 1970's. While the conservation/environmental movement asked questions about preserving the Earth's resources, sustainable development includes questions about how human decisions affect the Earth's environment. Sustainable development of environmental pollution has been discussed over the last 20 year in most countries, but an important health problems of indoor air pollution became a social issues in recent years. We must develop global perspectives and maintain effective balance between available resources and human needs. The further understanding of the sustainable development of indoor air pollution is extremely useful in defining the components of healthful indoor air in major indoor environments. Additional information concerning more detailed housing characteristics, daily activity patterns, and seasonal factors which may influence indoor pollutants should provide important information on sustainable development in indoor air pollution.

국내 6개 주요도시에서 조사된 어패류 오염도 현황을 토대로 우리나라 사람들의 어패류 섭취를 통한 유기주석화합물 인체노출량을 예측하고, 이에 따른 위해도를 추계하였다. 본 연구결과를 살펴보면 갈치의 경우, 성인이 식품수급표에서 제시하는 일일섭취량 3.02g/day를 평생 섭취한다는 노출시나리오하에 평균일일노출량은 확률분포로 나타냈을 때 그 중간값이 6.48$\times$ $10^{-7}$ mg/kg/day, 상한치 95th percentile값이 8.78$\times$$10^{-7}$ mg/kg/day로 나타났음을 알 수 있다. 본 연구에서는 비발암독성영향을 평가하기 위하여 BMD$_{10}$ 을 활용한 참고치(Reference dose)를 예측하였다. 이 때 BMD$_{10}$은 10% 비교변화를 BMR으로 하였을때 해당하는 용량의 95% 하한치이다. 본 연구에서 활용한 BMD는 digestion에 의한 근육내의 IgE titer, T.spiraris larvae와 조직학에 의한 근육내 T.spiraris larvae에 근거하여 예측된 것으로 0.03 mg/kg/day이다. 참고치는 BMD$_{10}$ 0.03 mg/kg/day에 불확실성 계수 100을 고려한 값으로 0.003 mg/kg/day이며, 이 때 활용한 불확실성계수는 실험동물에서 인체로의 외삽과정에서 고려한 계수 10과 인구집단 내 민감그룹 고려를 위한 계수 10을 적용한 것이다. 각 어패류의 위험지수(50th percentile)를 살펴보면 고등어에서 2.04$\times$ $10^{-2}$으로 가장 높게 나타났으며, 소라에서 2.70$\times$ $10^{-5}$으로 가장 낮은 값을 나타냈다.

본 연구는 건강검진 목적으로 시행된 관상동맥 CT에서의 성별, 연령에 따른 관상동맥질환 발견율에 대 한 유용성과 글루코스, 총 콜레스테롤, 내장지방, 체질량지수, 중성지방, 고밀도지단백질(HDL), 저밀도지단백질(LDL) 각각의 인자들과 관상동맥질환과의 관련성에 대해 알아보았다. 총 299명의 수검자를 대상으로 후향적 분석을 실시한 결과 관상동맥질환 발견율에 대해서는 남성, 50세 이상에서의 유병율이 높은 것으로 나타났으며, 통계적으로 유의성을 보였다. 특히 남성의 유병율(37.9％)은 여성의 유병율(17.0%) 보다 약 ２배가 높은 것으로 확인되었다. 또한 관상동맥질환과 관계되는 혈액학적 요인으로는 글루코스와 고밀도 지단백질(HDL)이 통계적으로 유의성을 보였다. 관상동맥질환의 예방 및 관리를 위해서는 글루코스와 고밀도지단백질(HDL)의 조절이 필요할 것으로 보이며, 다른 혈액학적 인자들과는 통계적으로 유의성은 낮았지만, 관상동맥질환에 대한 관리의 필요성이 확인되었다. 주요 결과로서 선별검사 목적으로 관상동맥 CT의 사용은 방사선 피폭 등의 문제점으로 인해 수검자의 성별, 나이를 고려하여 시행하는 것이 좋을 것으로 생각되며, 관상동맥 CT 시행 이전에 비침습적인 방법들의 선행검사를 통한 관상동맥 질환 검사가 필요함을 제안한다．