Background: Chronic ankle instability (CAI) is a prevalent condition among Taekwondo athletes, often associated with pain, psychological factors, and impaired physical performance. However, few studies have investigated the relationship among ankle muscle strength, pain, kinesiophobia, and physical performance in Taekwondo athletes with CAI. Objects: This study aimed to examine the relationship between ankle muscle strength, pain, kinesiophobia, and physical performance in Taekwondo athletes with CAI. Methods: Forty Taekwondo athletes with CAI participated in the study. Pain was assessed using the Visual Analogue Scale (VAS), and kinesiophobia was measured with the Tampa Scale for Kinesiophobia-11 (TSK-11). Physical performance was evaluated using the single-leg vertical jump (SLVJ) and single-leg hop for distance. The strength of the ankle muscles is measured using a Smart KEMA strength sensor. Pearson’s correlation coefficients were calculated to determine relationships among variables. Results: SLVJ showed a significant negative correlation with VAS (r = –0.506, p < 0.01) and a positive correlation with strength of the ankle inversion with dorsiflexion (IDF) (r = 0.356, p < 0.05). VAS was negatively correlated with strength of the ankle eversion with plantarflexion (r = –0.365, p < 0.05), IDF (r = –0.371, p < 0.05) and inversion with plantarflexion (r = –0.370, p < 0.05). No significant correlations were found between TSK-11 and physical performance, pain, or ankle muscle strength outcomes. Conclusion: Pain intensity and ankle muscle strength in specific ankle positions are associated with SLVJ in Taekwondo athletes with CAI. These findings suggest that the intensity of pain and the strength of the ankle evertor and invertor at specific ankle joint positions should be considered when evaluating Taekwondo athletes with CAI. Furthermore, managing pain and implementing strengthening exercises for the ankle evertor and invertor can be recommended to improve SLVJ.

본 연구의 목적은 집단미술치료 프로그램이 만성 조현병 환자의 불안 민감성과 사회적 기술에 미치는 효과를 검증하기 위한 것이다. 연구대상 은 K시에 소재한 정신건강증진센터 회원인 만성 조현병 환자 9명이다. 연구기간은 2023년 5월 2일부터 2023년 6월 22일까지 주 2회, 90분씩 총 16회기의 집단미술치료 프로그램을 실시하였다. 연구도구로는 불안민 감성, 사회적 기술척도와 DAS, K-HTP 그림검사를 실시하였으며, 회기 및 단계별 변화양상을 기술하였다. 자료 분석은 SPSS 25.0을 사용하여 사전과 사후 검사의 변화를 대응표본 t검정으로 비교분석하였다. 본 연구 결과는 첫째, 집단미술치료 프로그램이 만성 조현병 환자의 불안민감성 에 통계적으로 유의미한 차이가 있었다. 둘째, 집단미술치료 프로그램이 만성 조현병 환자의 사회적 기술 전체, 자아통제, 협력 점수는 사전보다 는 증가하였으나 통계적으로 유의미한 차이는 없었다. 셋째, 질적 내용분 석 결과, 집단원 간의 상호작용을 통해 내재된 두려움의 정서를 수용하 는 긍정적인 변화를 보였다. 이상의 연구결과를 바탕으로 본 연구의 주 요 시사점과 제한점에 대해 논의하였다.

Background: Chronic nonspecific low back pain (CNLBP) is a common musculoskeletal condition among middle-aged adults, often causing physical limitations and reduced quality of life. Transcutaneous electrical nerve stimulation (TENS) is a widely used non-pharmacological method for pain relief and muscle modulation. Objectives: To compare the effects of two high-frequency, high-intensity TENS protocols on pain, muscle tone, and stiffness in individuals with CNLBP. Design: Single-blinded, randomized controlled trial. Methods: Twenty-eight individuals with CNLBP were randomly assigned to an experimental group (EG) or control group (CG). Both received 60 Hz, highintensity TENS twice weekly for four weeks. Pain equivalent current (PEC), visual analogue scale (VAS), pain degree (PD), muscle tone (Hz), and stiffness (N/m) were measured pre- and post-intervention by a blinded assessor. Results: The EG showed significant improvements in all outcomes (P<.05), while the CG showed significant change only in VAS scores. Between-group analysis showed greater reductions in pain and muscle-related variables in the EG. Conclusion: The EG protocol, with individualized intensity adjustments and targeted stimulation sites, was more effective than the CG protocol in improving pain, muscle tone, and stiffness in adults with CNLBP.

Purpose: This study evaluated the impact of a nursing simulation learning module for caring for patients with chronic obstructive pulmonary disease (COPD) on nursing knowledge, clinical competence, team psychological safety, and learning satisfaction among nursing students. Methods: A non-equivalent control-group pretest–posttest quasi-experimental design was used with 36 students (18 per group) assigned to either a simulation group or a lecture group. Data collected from June 8 to July 13, 2024, were analyzed using SPSS 27.0. Results: Nursing knowledge showed no significant between-group difference (F=1.32, p=.260) but improved over time (F=8.24, p=.007). Clinical competence showed a significant group-by-time interaction (F=58.33, p<.001). Team psychological safety (t=2.70, p=.012) and learning satisfaction (t=2.27, p=.030) were higher in the simulation group. Conclusion: These findings provide foundational data for developing simulation-based educational strategies in nursing curricula. The module may also be applied to the training of novice nurses in clinical settings, thereby contributing to enhanced nursing education and improved clinical practice.

목적 : 본 연구는 지역사회 만성 뇌졸중 환자를 대상으로 원격동작관찰훈련이 상지 기능과 근 활성도에 미치는 영향을 알아보고자 실시하였다. 연구방법 : 2023년 8월부터 2024년 2월까지 대전광역시 소재의 재활병원에서 외래재활을 받지 않고 다른 기관에서도 치료를 계획하지 않은 대상자 6명을 실험군으로, 병원 내에서 외래재활치료를 받는 대상자 5명을 대조군으로 선정하였다. 실험군은 원격재활을 기반으로 한 원격동작관찰훈련을 하였고, 대조군은 실험군과 동일한 과제를 수행하는 외래재활치료를 진행하였다. 치료에 대한 중재는 1일 1회 30분, 주 3회, 총 4주간 실시하였고, 치료 중재 전과 후의 상지 기능을 측정하기 위해 ARAT 평가척도(Action Research Arm Test)와 MFT 평가척도(Manual Function Test)를 사용하였고, 근 활성도를 평가하기 위해 표면 근활성도 평가척도인 sEMG (Surface Electromyography)를 사용하였다. 결과 : 두 집단 각각의 중재 전과 후 결과 상지기능과 근 활성도 일부 항목에서 유의한 차이를 보였으며(p < 0.05), 중재 후 두 집단 간에서는 상지기능과 근 활성도에서 유의한 차이를 보이지 않았다(p < 0.05). 결론 : 본 연구에서의 결과로 원격동작관찰훈련이 지역사회 만성 뇌졸중 환자에게 외래재활치료와 유사하게 기능 향상을 시킬 수 있는 중재방법이자, 접근성과 경제적인 이점이 있어 지역사회 만성 뇌졸중 환자에게는 효율적인 방법으로 제시될 수 있다.

Background: Chronic low back pain (CLBP) is associated with trunk and lower extremity muscle weakness. Kneeling squat (KS) is a hip-focused exercise commonly used in the activities of daily living. However, research on trunk and lower extremity muscle activity across movement phases (ascending, holding, and descending) during KS remains limited and warrants further investigation. Objects: To determine the muscle activity of transversus abdominis/internal oblique (TrA/IO), erector spinae, gluteus maximus (Gmax), gluteus medius (Gmed), rectus femoris (RF) in the contraction phases of KS in individuals with CLBP. Methods: Surface electromyography data were recorded during KS across the ascending, holding, and descending phases on the side with CLBP. A 60-bit metronome was used to control the exercise speed. Results: The muscle activity of the TrA/IO was significantly higher during the holding phase than during the ascending and descending phases. The Gmax and Gmed were significantly higher during the holding phase than during the descending phase, whereas, RF was significantly higher during the ascending phase than during the holding and descending phases. Conclusion: The holding phase of KS may be recommended as a trunk and lower extremity exercise to increase in TrA/IO, Gmax, and Gmed muscle activity. Additionally, the ascending phase activates RF muscle in individuals with CLBP.

Background: Chronic low back pain (CLBP) is a common health problem among female caregivers. In Korea, 70.4% of caregivers experience LBP after caregiving. The prevalence of LBP was higher in female caregivers of patients who required physical assistance with transfer than in those caring for patients who did not require physical assistance. Lifting movements, such as patient transfer and positioning, are associated with lumbopelvic stability (LPS) and knee muscle strength. However, no studies have investigated the differences in LPS and knee muscle strength between female caregivers with and without CLBP. Objects: This study was conducted to investigate the differences of the LPS, knee extension strength (KES) and knee flexion strength (KFS) between female caregivers with and without CLBP. Methods: Thirty-one female caregivers participated in this study. Participants were divided into two groups: (1) caregivers without CLBP (n = 13) and (2) caregivers with CLBP (n = 18). LPS, KES, and KFS levels were measured. An independent t-test was used to compare the LPS, KES, and KFS between caregivers with and without CLBP. The statistical significance was set at α of 0.05. Results: The LPS and KES scores were significantly lower in caregivers with CLBP than those without. In contrast, the KFS did not differ significantly between the groups. Conclusion: This study observed associations of both LPS and KES with CLBP among female caregivers.

Background: Stroke often results in impaired postural control and asymmetric weight distribution, which negatively affect balance and functional mobility. Previous research has demonstrated that balance training interventions incorporating proprioceptive stimulation and visual feedback can enhance postural stability in stroke survivors. However, there remains debate regarding the relative effectiveness of these two approaches. While proprioception-based training emphasizes sensory input from mechanoreceptors to improve postural control, visual feedback-based training leverages external cues to facilitate balance adjustments. Objectives: To investigation the effects of proprioception-based trunk exercise and visual-auditory feedback-based trunk exercise on sitting balance in patients with chronic stroke. Design: Randomized controlled trial. Methods: A total of 24 participants diagnosed with chronic stroke were randomly assigned to two groups: the proprioception-based trunk exercise group (PTG, n=10) and the visual-auditory feedback-based trunk exercise group (VTG, n=11). Both groups participated in a 6-week intervention program, five sessions per week, lasting 25 minutes per session. Outcome measures included the Limitation of Stability (LOS), the Korean version of the Trunk Impairment Scale (K-TIS), and the Postural Assessment Scale for Stroke (PASS). Pre- and post-intervention assessments were analyzed using paired t-tests and independent t-tests to evaluate within-group and between-group differences. Results: Both PTG and VTG groups demonstrated significant improvements in LOS, K-TIS, and PASS scores following the intervention (P<.05). However, there were no statistically significant differences between the two groups in the amount of change observed. Conclusion: The findings suggest that both proprioception-based and visualauditory feedback-based trunk exercises are effective in improving sitting balance in chronic stroke patients. The lack of a significant difference between the groups indicates that both approaches provide comparable benefits. Future research should explore long-term effects and investigate potential differences in various functional domains beyond sitting balance.

Chronic enteropathy (CE) in dogs presents with persistent symptoms such as vomiting, diarrhea, weight loss, and changes in appetite. Traditional diagnostic methods, including blood tests, ultrasound, and endoscopy, often fail to assess the entire small intestine. Capsule endoscopy offers a non-invasive approach, enabling comprehensive visualization of the gastrointestinal tract and enhancing diagnostic accuracy. In case 1, a 10-year-old Maltese with chronic diarrhea and significant weight loss underwent capsule endoscopy, revealing severe lacteal dilation and moderate gastric erythema, leading to a diagnosis of severe intestinal lymphangiectasia and moderate enteritis. Despite initial corticosteroid therapy and dietary changes, clinical improvement was limited. In case 2, an 11-year-old mixed-breed dog with chronic vomiting, anorexia, and weight loss was assessed. Capsule endoscopy detected moderate gastric erythema, severe small intestinal irregularities, and jejunal bleeding, diagnosing mild esophagitis, moderate gastritis, and severe enteritis with hemorrhage. Treatment with a hypoallergenic diet, corticosteroids, and acid suppressants resulted in gradual symptom relief. This report demonstrates that capsule endoscopy can be utilized as a screening tool for evaluating the mucosal status in patients with CE.

Background: Chronic ankle instability (CAI) is very common disease. Strength exercise, balance exercise, and proprioceptive exercise were used to improvement of function for CAI. Isokinetic strength and balance are related to functional movement of lower extremity. Objectives: The purpose was to analyze the effect of muscle strengthening exercise, balance exercise, and proprioceptive exercise on isokinetic strength and balance in young adults with CAI. Design: Randomized controlled trial. Methods: The subjects were 30 young adults with CAI. The subjects randomly divided into three groups: strengthening exercise, balance exercise, and proprioceptive exercise. They performed each exercise for 20 minutes, three times a week for four weeks. They measured isokinetic strength of dorsiflexor and plantar flexor of 60°/sec and 120°/sec, static and dynamic balance before and after exercise. Results: The isokinetic strengths of dorsiflexor and plantar flexor of 60°/sec and 120°/sec were significantly higher in the strengthening exercise group than in the balance exercise group. The static and dynamic balance was significantly higher in the balance exercise group than in other two groups. Conclusion: Strengthening exercise, balance exercise, proprioceptive exercise can improve the muscle strength for CAI. Strengthening exercise and balance exercise can more improve balance than proprioceptive exercise for CAI.

Background: For patients with neck pain, a taping method has been used to promote thoracic spine extension. To induce thoracic spine extension without back pain, a neutral lumbo-pelvic position must be established. The spiral trunk taping method can induce a neutral lumbo-pelvic position and thoracic spine extension. Objectives: To determine the effectiveness of spiral trunk taping in inducing thoracic spine extension and neutral lumbo-pelvic position in patients with neck pain. Design: A randomized controlled trial. Methods: Thirty patients with neck pain were randomly assigned to groups. The experimental group received spiral trunk taping and the control group received sham taping. The resting position visual analogue scale (VAS) and VAS during painful movement were measured and compared pre and post treatment. Results: Significant within-subjects changes were resting position VAS (F=59.823, P=0.001) and VAS during painful movement (F=76.128, P=0.001). Significant between-subject changes were resting position VAS (F=10.402, P=0.003) and VAS during painful movement (F=7.657, P=0.01). Conclusion: Spiral trunk taping, which can induce thoracic spine extension and a neutral lumbo-pelvic position, was effective for neck pain. This study demonstrates the potential of a systemic taping approach in the management of neck pain, and provides important clues for future clinical applications.

Background: In Taekwondo athletes, ankle sprain is the most common risk factor for injury. Repeated ankle injuries lead to weakness and imbalance of the ankle muscles, resulting in chronic ankle instability (CAI). Both the ankle and toe muscles contribute to the inversion and eversion of the foot at the subtalar joint. Therefore, it is necessary to consider the ankle and toe joint positions when measuring ankle invertor and evertor strength. Objects: This study aimed to compare the muscle strength and ratio differences of the ankle invertor and evertor muscles in both the toe and ankle positions between the CAI and uninjured sides in Taekwondo athletes. Methods: Fifteen Taekwondo athletes participated in this study. The isometric strengths of both the ankle invertor and evertor were determined in different ankle and toe positions (dorsiflexion with toe extension, dorsiflexion with toe flexion, plantarflexion with toe extension, and plantarflexion with toe flexion). Paired t-tests were used to determine the differences between the ankle invertor and evertor in strength and ratio according to toe and ankle positions between the ankle CAI side and the uninjured side. Results: The results demonstrated that ankle evertor strength significantly decreased in all ankle and toe positions on the CAI side (p < 0.05). In addition, significant differences were observed in the ratios of the ankle invertor and evertor strengths in the dorsiflexion with toe flexion, plantarflexion with toe extension, and plantarflexion with toe flexion positions (p < 0.05). Conclusion: The findings of this study suggest that athletes, trainers, and clinicians should consider ankle and toe positions when measuring invertor and evertor strength and develop ankle rehabilitation protocols for Taekwondo athletes with CAI.

Background: Most patients with chronic stroke have difficulty walking, and various exercise methods are used clinically to improve the disability. Among them, various methods are being applied to improve walking through torso movement. Objectives: This study was conducted to determine the effect of Maitland vertebra joint mobilization exercise and Evjenth trunk muscle stretching exercise on the walking ability of patients with hemiparesis due to chronic stroke. Design: A randomized controlled trial. Methods: In this study, 30 chronic stroke patients with hemiplegia were divided into 15 patients in the Maitland vertebra joint mobilization group (MVJMG) and 15 in the Evjenth trunk muscle stretching exercise group (ETMSEG), and the intervention was conducted for 3 weeks, 5 times a week, 30 minutes a day. After the intervention, walking ability was measured using a gait analyzer. Results: In terms of walking ability, there was a significant increase in walking rate, walking speed, and stride length following the intervention in both the MVJMG and ETMSEG groups (P<.05). When comparing the difference in walking ability between the two groups, there was no significant difference in walking rate. Conclusion: The study found that both Maitland vertebra joint mobilization and Evjenth trunk muscle stretching exercises were effective for improving walking function in chronic stroke patients. However, there was no significant difference in effectiveness between the two interventions.

현대사회에서 스트레스와 긴장감은 피할 수 없는 요인이다. 다양한 피부질환은 스트레스를 일 으키는 중요한 요인으로 언급되고 있다. 피부질환을 가진 환자들은 수면상태가 원활하지 않아 전반적으로 수면 효율이 낮다. 또한 피부질환으로 인해 심리적 스트레스 수치가 높아지고, 이와 같은 과정은 반복적으 로 발생하고 있다. 피부질환과 스트레스는 상호적으로 연관되어 있으며, psychodematology에 대한 연구가 증가하고 있다. 이에 본 연구에서는 피부질환을 저하 시킬 수 있는 호박, 작약, 타트체리 복합물을 활용하 여 피부 각질 형성 세포에서 스트레스로 인한 만성 피부질환을 개선할 수 있는 소재를 개발하고 효능을 입 증하고자 하였다. HaCaT 각질형성세포에 복합 추출물은 12.5, 25, 50, 100 μg/mL 농도 의존적으로 TNF-α, IL-1β, IL-6, MDC, TARC 발현량이 저해되었으며 특히 IL-1β의 경우, 100 μg/mL의 농도 에서 40% 이상 저해하는 우수한 효능을 확인하였다. 또한 AQP-3, HA, filaggrin의 생성량 농도 의존적으 로 유의미한 증가를 보이며 TNF-α/IFN-γ로 증가된 p-ERK, p-JNK, p-p38의 단백질 발현은 복합 추 출물의 처리로 유의하게 감소시 키는 것으로 나타났다. 이를 통하여 해당 복합 추출물은 피부질환을 치료 및 예방할 수 있는 소재로서 활용가치가 있는 것으로 판단되며, 이는 피부질환과 스트레스 간의 상호 관계 의 악영향을 낮춰 줄 것으로 판단된다.

만성췌장염은 췌장암 발생의 위험인자 중 하나로, 췌장암 감시가 주목을 받고 있다. 유전자 변이 여부에 따라 유전성 만성췌장염과 산발성 만성췌장염으로 분류할 수 있다. PRSS1 변이 유전성 만성췌장염의 경우 췌장암 발생 위험이 매우 높아 40세 이후 선별 검사 및 추적 감시가 필요하다. 그 외의 유전성 만성췌장염 및 산발성 만성췌장염에서 췌장암의 발생률은 상대적으로 낮아 선별 검사 및 추적 감시를 권고하지 않는다. 췌장암 선별검사의 방법으로 복부컴퓨터단층촬영 또는 췌장자기공명영상이 적합하다. 내시경초음파는 췌장실질의 염증, 섬유화 및 석회화로 인하여 권유하지 않는다. 산발성 만성췌장염에서도 다양한 췌장암 위험인자가 동반되는 경우 췌장암의 발생 빈도가 상당히 증가하고 만성췌장염 진단 후 5년 동안은 췌장암 발생률이 지속적으로 높아 환자의 증상 및 개별적 상황에 따른 췌장암 선별 검사 시행 및 추적 감시를 고려할 수 있다. 만성췌장염은 영양실조 발생이 높으므로 관심, 영양상태 평가 및 적극적인 영양요법이 필요하다. 필수 영양소 공급뿐만 아니라 미량영양소 공급을 놓치지 않도록 한다. 그리고 만성췌장염 환자에서 골다공증 또는 골감소증의 위험이 높음을 인지하고 이의 진단, 예방 및 치료에 관심을 둘 필요가 있다. 각 기관의 영양지원팀에 의뢰하여 적극적으로 영양요법을 시행하는 것도 도움이 되겠다.

Background: Various treatments are being tried for lumbar neuropathy. Among them, neural mobilization aims to reduce peripheral nerve sensitivity by stimulating them directly. Similarly, applying kinesiotape stimulates skin and joint receptors around the nerves, thereby affecting nerve function and movement. Objectives: To investigated the effect of low back pain on the neural mobilization and kinesiotaping. Design: Randomized controlled trial. Methods: Thirty patients with chronic low back pain were randomly allocated to three groups: the neural mobilization exercise with kinesiotaping group (NEKTG, n=10), the neural mobilization exercise group (NEG, n=10), and the kinesiotaping group (KTG, n=10). Each group performed six intervention sessions over two weeks. The results were analyzed by measuring the numeric pain rating scale (NPRS) and straight leg raise (SLR) before and after the intervention in each group. Results: NEKTG, NEG, and KTG all indicated a significant decrease in the back pain index before and after the intervention. However, there were no differences observed between the three groups. The SLR angles before the experiment were identical across the three groups. The SLR angles before and after the intervention were as follows: the SLR angle significantly increased in NEKTG. Furthermore, there was a significant increase in the SLR angle in NEKTG compared to both NEG and KTG. Conclusion: Neural mobilization combined with kinesiotaping provided better therapeutic effects regarding pain reduction and neurodynamic improvement compared to alone kinesiotaping and mobilization with chronic low back pain.

Background: Chronic back pain not only causes physical discomfort and decreased functionality but also affects emotional well-being, resulting in feelings of anxiety, depression, and other psychological issues. Studies have indicated that cognitive functional therapy and motor control exercises can alleviate chronic low back pain and associated psychological issues. Objectives: To investigated the effect of chronic low back pain on the cognitive functional therapy (CFT) and motor control exercises (MCE). Design: Quaxi-experimental study. Methods: Forty patients with chronic low back pain were randomly assigned and divided into 20 cognitive functional therapy group with motor control exercises group (CFTMG) and 20 patients in motor control exercises group (MCEG). After applying CFT with motor control exercises and motor control exercises for 8 weeks, changes in numeric pain rating scale (NPRS), Oswestry disability index (ODI) and Fear-avoidance beliefs questionnaire (FABQ) were observed. Results: In the CFTMG, statistically significant changes were observed in NPRS, ODI, and FABQ before and after the intervention. In the MCEG, statistically significant changes were observed in VAS and ODI before and after the intervention. Conclusion: The application of CFTM and MCE in patients suffering from chronic low back pain has demonstrated effectiveness in alleviating pain, enhancing back function, and reducing kinesiophobia associated with the condition.

Background: Ankle sprains occur frequently among humans who undertake various body movements. Diverse walking environments and dual tasks, that can affect ankle sprains, have been studied. However, there is a lack of research on inter-trial variability according to the changes in gait speed. Objects: The purpose of this study was to compare the adaptive ability of walking between the subjects with chronic ankle instability and healthy adults while performing a walking task with different walking speeds. Methods: In this study, 24 people in the chronic ankle instability group and 24 people in the healthy ankle group were selected as subjects. The length of the pre-measurement and the actual walking measurement were both set to 4.6 m. Once the subjects entered the measurement section, they changed their gait speed according to the randomly assigned speed change. Gait was measured twice and the average value was used for the analysis. Results: The coefficient of variation (CV) of cycle time in subjects with chronic ankle instability showed a significant difference in all cases except when the subjects changed their speed from preferred to slow and from slow to preferred. The CV of step length demonstrated a significant difference in all cases except for the change from slow to preferred and from preferred to fast. The cycle time and step length differential showed a significant difference only when the subjects changed the speed from slow to fast. Conclusion: The subjects with chronic ankle instability were found to have significantly reduced walking adaptability while performing inter-trial variability tasks with different gait speeds compared to healthy subjects.

Potentillae Chinensis Herba 추출물의 항산화 효능 평가를 위해 DPPH 자유라디칼 소거 활성 과 ABTS 양이온 라디칼 활성 평가를 시행하였다. 세포 실험에서 항염증 평가를 위해 호흡기 점막 상피세 포 NCI,H292와 RAW264.7 세포 대상으로 항염증 효능을 평가하였다. 그 결과, DPPH 자유라디칼 소거 활성과 ABTS 양이온 라디칼 활성 모두 농도 의존적으로 항산화 활성이 증가하는 것으로 나타났다. 세포 MTT 분석 결과, 각 농도 100 μg/ml로 처리한 경우 NCI-H292 세포의 생존율이 70% 미만으로 감소하 였고, 이후 실험은 50 μg/ml로 진행하였다. 항염증 효능 평가에서는 NO생성, TNF-α, IL-1β, PGE2가 감소하였고, COX-2도 50 μg/ml에서 유의하게 감소하였다. Potentillae Chinensis Herba 추출물과 생물 전환 추출물의 뮤신 단백질 발현은 MUC5AC 발현이 유의하게 감소하는 것으로 관찰되었다. 이상의 결과 는 Potentillae Chinensis Herba의 호흡기 점액 단백질 발현을 도와 염증을 억제하는 기능성 소재로 활용하 는데 가치가 있음을 알 수 있다.

본 연구는 일회성 발목가동성 운동프로그램이 만성적인 발목불안정성(CAI)에 나타나는 발목가 동범위와 통증 수준에 미치는 영향을 확인하는데 목적이 있다. 연구 대상자는 발목불안정성 설문지 검사에 서 좌, 우측 평균 점수가 24점 이하인 성인여성 20명을 선정 하였으며 집단은 일회성 발목 가동성 운동프 로그램 집단(Ankle mobility exercise program, AE, n=10)과 대조군(CON, n=10)으로 구분하였다. AE 처 치는 일회성 운동에 대한 반응을 확인하기 위해 좌·우측 발목을 각각 1회(20분) 실시하였으며 처치 전후 발목불안정성 검사, 통증 및 발목가동범위를 확인하였다. 먼저 AE 프로그램을 실시한 AE 집단의 통증 수 준은 사전과 비교하여 사후 유의하게 감소하는 것으로 나타났다(p<.01). 또한 AE 프로그램 처치한 AE 집 단에서 배측굴곡이 사전과 비교하여 증가하는 것으로 나타났다(p<.05). 이러한 결과를 종합해 보면 일회성 발목 가동성 운동 프로그램은 CAI에서 나타나는 발목 통증과 발목의 가동범위를 개선시켜 결과적으로 발 목 불안정성을 완화시킬 수 있는 효과적인 운동 중재 방법이라고 생각된다.